利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

11 条记录 (耗时 0.025 秒)

    METHODS OF PROGNOSIS AND TREATMENT
    1.
    发明申请
    METHODS OF PROGNOSIS AND TREATMENT 审中-公开
    预后和治疗方法

    公开(公告)号：WO2018060998A1

    公开(公告)日：2018-04-05

    申请号：PCT/IL2017/051088

    申请日：2017-09-27

    申请人： MEMED DIAGNOSTICS LTD.

    发明人： EDEN, Eran ,  OVED, Kfir ,  COHEN-DOTAN, Assaf ,  NAVON, Roy ,  BOICO, Olga ,  PAZ, Meital

    IPC分类号： G01N33/68

    摘要： A method of determining a management course for treating a subject showing symptoms of a disease is disclosed. The method comprises measuring the TRAIL protein level in a blood sample of the subject, wherein when the TRAIL level is below a predetermined amount, the subject is treated as a high-risk patient.

    摘要翻译： 公开了确定用于治疗显示疾病症状的受试者的管理过程的方法。 该方法包括测量受试者的血液样品中的TRAIL蛋白质水平，其中当TRAIL水平低于预定量时，该受试者被视为高风险患者。

    METHODS OF RISK ASSESSMENT AND DISEASE CLASSIFICATION
    4.
    发明申请
    METHODS OF RISK ASSESSMENT AND DISEASE CLASSIFICATION 审中-公开
    风险评估和疾病分类方法

    公开(公告)号：WO2018060999A1

    公开(公告)日：2018-04-05

    申请号：PCT/IL2017/051089

    申请日：2017-09-27

    申请人： MEMED DIAGNOSTICS LTD.

    发明人： OVED, Kfir ,  EDEN, Eran ,  COHEN-DOTAN, Assaf ,  NAVON, Roy ,  MASTBOIM, Niv Steven ,  BOICO, Olga ,  PAZ, Meital

    IPC分类号： G01N33/68

    摘要： A method of measuring risk assessment in a patient is disclosed. The method comprises: (a) measuring the TRAIL protein level in a blood sample of the patient; (b) measuring the level of at least one disease-associated parameter in the patient; and (c) providing a risk assessment based on the combination of said TRAIL protein level and said disease-associated parameter level.

    摘要翻译： 公开了一种测量患者风险评估的方法。 该方法包括：（a）测量患者血液样品中的TRAIL蛋白质水平; （b）测量患者中至少一种疾病相关参数的水平; 和（c）基于所述TRAIL蛋白质水平和所述疾病相关参数水平的组合提供风险评估。

    COMPUTATIONAL ANALYSIS OF BIOLOGICAL DATA USING MANIFOLD AND A HYPERPLANE
    5.
    发明申请
    COMPUTATIONAL ANALYSIS OF BIOLOGICAL DATA USING MANIFOLD AND A HYPERPLANE 审中-公开
    生物数据的计算分析使用歧管和高压

    公开(公告)号：WO2016024278A1

    公开(公告)日：2016-02-18

    申请号：PCT/IL2015/050823

    申请日：2015-08-12

    申请人： MEMED DIAGNOSTICS LTD.

    发明人： EDEN, Eran ,  OVED, Kfir ,  NAVON, Roy ,  COHEN-DOTAN, Assaf ,  BOICO, Olga

    IPC分类号： G01N33/569

    CPC分类号： G06F19/12 ,  G06F17/18 ,  G06F19/00 ,  G06F19/18 ,  G06F19/20 ,  G06F19/24 ,  G16H50/50 ,  Y02A90/26

    摘要： A method of analyzing biological data containing expression values of a plurality of polypeptides in the blood of a subject. The method comprises: calculating a distance between a segment of a curved line and an axis defined by a direction, the distance being calculated at a point over the curved line defined by a coordinate along the direction. The method further comprises correlating the distance to the presence of, absence of, or likelihood that the subject has, a bacterial infection. The coordinate is defined by a combination of the expression values, wherein at least 90% of the segment is between a lower bound line and an upper bound line.

    摘要翻译： 一种分析含有受试者血液中多种多肽表达值的生物数据的方法。 该方法包括：计算曲线段和由方向限定的轴之间的距离，所述距离在由沿着该方向的坐标定义的曲线上的点处计算。 该方法还包括将距离与受试者的存在，不存在或可能性相关联的细菌感染。 坐标由表达值的组合定义，其中该段的至少90％在下限线和上限线之间。

    SYSTEM AND METHOD FOR ANALYSIS OF BIOLOGICAL DATA
    6.
    发明申请
    SYSTEM AND METHOD FOR ANALYSIS OF BIOLOGICAL DATA 审中-公开
    用于分析生物数据的系统和方法

    公开(公告)号：WO2018029690A1

    公开(公告)日：2018-02-15

    申请号：PCT/IL2017/050886

    申请日：2017-08-10

    申请人： MEMED DIAGNOSTICS LTD.

    发明人： OVED, Kfir ,  EDEN, Eran ,  NAVON, Roy ,  COHEN-DOTAN, Assaf ,  KRONENFELD, Gali ,  BOICO, Olga

    IPC分类号： G01N33/569

    摘要： A method of analyzing biological data is disclosed. The method comprises obtaining biological data containing at least an expression level of MX dynamin-like GTPase 1 (MX1) and an expression level of C-reactive protein (CRP) in the blood of a subject, calculating a distance between a segment of a curved line and an axis defined by a direction, the distance being calculated at a point over the curved line defined by a coordinate along the direction, and correlating the distance to the presence of, absence of, or likelihood that the subject has, a bacterial infection.

    摘要翻译： 公开了一种分析生物数据的方法。 该方法包括获得至少包含受试者血液中MX发动蛋白样GTP酶1（MX1）表达水平和C-反应蛋白（CRP）表达水平的生物学数据，计算曲线的一段 线和由方向定义的轴，所述距离在由沿着该方向的坐标定义的曲线上方的点处计算，并且将该距离与受试者具有的细菌感染的存在，不存在或可能性相关联

    ANALYZING RNA FOR DIAGNOSING INFECTION TYPE
    8.
    发明申请
    ANALYZING RNA FOR DIAGNOSING INFECTION TYPE 审中-公开
    分析RNA用于诊断感染类型

    公开(公告)号：WO2017149547A1

    公开(公告)日：2017-09-08

    申请号：PCT/IL2017/050270

    申请日：2017-03-02

    申请人： MEMED DIAGNOSTICS LTD.

    发明人： EDEN, Eran ,  OVED, Kfir ,  COHEN-DOTAN, Assaf ,  NAVON, Roy ,  BOICO, Olga ,  KRONENFELD, Gali ,  SIMON, Einav

    IPC分类号： C12Q1/00 ,  C12Q1/68 ,  G01N33/569

    摘要： A method of selecting an exon of an RNA whose expression level is informative with respect to infection type of a subject is disclosed. The method comprises comparing the expression level of the RNA in a sample derived from a bacterially- infected subject and a sample derived from a virally-infected subject at a plurality of exons, wherein the exon that provides a differential expression between the bacterially- infected subject and the virally-infected subject above a predetermined level is selected as the exon of the RNA whose expression is informative with respect to infection type.

    摘要翻译： 公开了一种选择RNA表达水平对受试者的感染类型提供信息的RNA的外显子的方法。 该方法包括比较来自细菌感染对象的样品中的RNA和来自病毒感染对象的样品在多个外显子中的表达水平，其中在细菌感染对象之间提供差异表达的外显子 并选择超过预定水平的病毒感染对象作为其表达对感染类型有信息的RNA的外显子。