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    SYSTEM FOR DETERMINING THE CLEANLINESS OF MASS SPECTROMETER ION OPTICS
    3.
    发明申请
    SYSTEM FOR DETERMINING THE CLEANLINESS OF MASS SPECTROMETER ION OPTICS 审中-公开

    公开(公告)号：WO2022043695A1

    公开(公告)日：2022-03-03

    申请号：PCT/GB2021/052222

    申请日：2021-08-26

    Applicant: MICROMASS UK LIMITED

    Inventor： GORDON, David ,  LUMLEY, Nicola ,  BOOTH, Alastair ,  MOULDS, Richard

    IPC: H01J49/00

    Abstract: A mass spectrometer is disclosed comprising: an ion detector; ion optics for guiding ions to the ion detector; one or more voltage supply for supplying voltages to said ion optics; control circuitry for controlling the one or more voltage supply so as to switch the ion optics between operating in a first mode in which the ion optics are unable to transmit ions having a first mass to charge ratio or first polarity to the ion detector and a second mode in which the ion optics are able to transmit ions having said first mass to charge ratio or first polarity to the ion detector for a time period; and to repeatedly switch between the first and second modes a plurality of times; and a processor and circuitry configured to: (i) determine the intensity of an ion signal detected by the detector at a first time in each of the time periods that the ion optics are in the second mode; and (ii) determine the intensity of the ion signal detected by the detector at a second, later time in each of the time periods that the ion optics are in the second mode.

    A METHOD OF PERFORMING A ROUTINE ON A MASS SPECTROMETER
    6.
    发明申请
    A METHOD OF PERFORMING A ROUTINE ON A MASS SPECTROMETER 审中-公开

    公开(公告)号：WO2019229449A1

    公开(公告)日：2019-12-05

    申请号：PCT/GB2019/051490

    申请日：2019-05-31

    Applicant: MICROMASS UK LIMITED

    Inventor： BOOTH, Alastair ,  CHUA, Alvin ,  CHEN, Carl ,  DRABBLE, Darren ,  JONES, Rhys ,  ONG, Dennis ,  ROCHA, Steven

    IPC: H01J49/00

    Abstract: A method of performing a routine on a mass spectrometer, comprising: providing a reference sample having known chemical properties; generating a test mass spectrum from the reference sample using the mass spectrometer; comparing predetermined characteristics of the test mass spectrum to predetermined performance criteria; performing an autotune procedure on the mass spectrometer if a first characteristic of the test mass spectrum is deemed not to meet corresponding predetermined performance criteria; performing a resolution adjustment and calibration procedure on the mass spectrometer if a second characteristic of the test mass spectrum is deemed not to meet corresponding predetermined performance criteria.

    ION GUIDE
    7.
    发明申请
    ION GUIDE 审中-公开

    公开(公告)号：WO2019229448A1

    公开(公告)日：2019-12-05

    申请号：PCT/GB2019/051489

    申请日：2019-05-31

    Applicant: MICROMASS UK LIMITED

    Inventor： BOOTH, Alastair ,  CHUA, Alvin ,  CHEN, Carl ,  ONG, Dennis ,  TYLDESLEY-WORSTER, Richard

    IPC: H01J49/06

    Abstract: An ion guide (10) comprising an inlet (11) having a first longitudinal axis (12), a middle section (15) and an outlet (13) having a second longitudinal axis (14), wherein the inlet, middle section and outlet together define an ion path, the first axis is substantially co-axial with the second axis, and the middle section is non-linear.

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