公开(公告)号：WO2016130569A4

公开(公告)日：2016-11-10

申请号：PCT/US2016017183

申请日：2016-02-09

申请人： MJ BIOLOGICS INC ,  PHIBRO ANIMAL HEALTH CORP

发明人： KIM BYOUNG KWAN ,  BROWN KAREN ,  MILLER LARRY

IPC分类号： A61K39/12

CPC分类号： A61K39/215 ,  A61K39/12 ,  A61K2039/5252 ,  A61K2039/54 ,  A61K2039/541 ,  A61K2039/543 ,  A61K2039/55 ,  A61K2039/552 ,  A61K2039/55511 ,  A61K2039/55555 ,  A61K2039/55566 ,  A61K2039/57 ,  C07K14/005 ,  C12N7/00 ,  C12N2770/20034 ,  C12N2770/20051 ,  C12N2770/20063

摘要： Disclosed herein are embodiments of an immunogenic composition for porcine epidemic diarrhea virus, and a method for making the immunogenic composition. Also disclosed is a method for administrating the immunogenic composition to a subject in need thereof. The immunogenic composition comprises PEDV proteins and/or antigens from one or more strains of PEDV, and may additionally comprise proteins and/or antigens from one or more additional porcine pathogens, such as PRRSV. Additionally disclosed in a combination comprising a PEDV immunogenic composition as disclosed herein, and an immunogenic composition or other therapeutic composition directed toward an additional porcine pathogen.

摘要翻译： 本文公开了猪流行性腹泻病毒的免疫原性组合物的实施方案，以及制备免疫原性组合物的方法。 还公开了将有针对性的受试者给予免疫原性组合物的方法。 免疫原性组合物包含来自一种或多种PEDV菌株的PEDV蛋白和/或抗原，并且还可以包含来自一种或多种另外的猪病原体如PRRSV的蛋白质和/或抗原。 另外公开在包含本文公开的PEDV免疫原性组合物和免疫原性组合物或针对另外的猪病原体的其它治疗组合物的组合中。