公开(公告)号：WO2014092861A1

公开(公告)日：2014-06-19

申请号：PCT/US2013/065555

申请日：2013-10-18

Applicant: MJN U.S. HOLDINGS LLC

Inventor： POELS, Eduard K. ,  RUDOLPH, Colin ,  VAN DAEL, Peter ,  WITTKE, Anja ,  MCMAHON, Robert J.

IPC: A23L1/29

CPC classification number: A23L1/296 ,  A23L33/17 ,  A23L33/40 ,  A23V2002/00 ,  A23V2200/332

Abstract: Provided herein are nutritional compositions comprising a protein source, a fat source, a carbohydrate source, and at least one nucleotide, wherein the protein source comprises at least one free amino acid, wherein the at least one free amino acid comprises a glutamate salt, glutamic acid, taurine, glutamine, alanine, or any combination thereof. Also provided herein are methods of promoting satiety, preventing or reducing the incidence of overweight or obesity, or preventing or reducing the incidence of diabetes in a subject comprising administering to a subject a nutritional composition comprising a protein source, a fat source, a carbohydrate source, and at least one nucleotide, wherein the protein source comprises at least one free amino acid, wherein the at least one free amino acid comprises a glutamate salt, glutamic acid, taurine, glutamine, alanine, or any combination thereof.

Abstract translation: 本文提供了包含蛋白质源，脂肪源，碳水化合物源和至少一个核苷酸的营养组合物，其中所述蛋白质来源包含至少一种游离氨基酸，其中所述至少一种游离氨基酸包含谷氨酸盐，谷氨酸 酸，牛磺酸，谷氨酰胺，丙氨酸或其任何组合。 本文还提供了促进饱腹感，预防或减少超重或肥胖的发生率或预防或减少受试者中糖尿病发病率的方法，包括向受试者施用包含蛋白质来源，脂肪来源，碳水化合物来源的营养组合物 和至少一个核苷酸，其中所述蛋白源包含至少一种游离氨基酸，其中所述至少一种游离氨基酸包含谷氨酸盐，谷氨酸，牛磺酸，谷氨酰胺，丙氨酸或其任何组合。

公开(公告)号：WO2016195888A1

公开(公告)日：2016-12-08

申请号：PCT/US2016/030500

申请日：2016-05-03

Applicant: MJN U.S. HOLDINGS LLC

Inventor： KUANG, Chenzhong ,  XIAO, Yan ,  RUDOLPH, Colin ,  HONDMANN, Dirk

IPC: A23L33/00 ,  A23L33/10 ,  A23L33/125

CPC classification number: A61K31/047 ,  A23L33/40 ,  A23V2002/00 ,  A23V2200/322 ,  A23V2250/641 ,  A61K31/715 ,  A61K47/12 ,  A61K47/26 ,  A61K47/42

Abstract: A method for enhancing neurological health and development in a subject involving administering to the subject a nutritional composition including no greater than about 7 g/100 kcal of a fat or lipid source; no greater than about 7 g/100 kcal of a protein or protein equivalent source; at least about 5 g/100 kcal of a carbohydrate; and at least about 9 mg/100 kcal of inositol, wherein the ratio of exogenous inositol to inherent inositol is at least 50:50.

Abstract translation: 一种用于增强受试者的神经系统健康和发育的方法，包括对受试者施用包含不超过约7g / 100kcal脂肪或脂质来源的营养组合物; 不超过约7g / 100kcal的蛋白质或蛋白质当量来源; 至少约5g / 100kcal的碳水化合物; 和至少约9mg / 100kcal的肌醇，其中外源肌醇与固有肌醇的比例为至少50:50。

公开(公告)号：WO2017011132A1

公开(公告)日：2017-01-19

申请号：PCT/US2016/037772

申请日：2016-06-16

Applicant: MJN U.S. HOLDINGS LLC

Inventor： AO, Zihua ,  BERSETH, Carol Lynn ,  COBB, Patricia ,  GONZALEZ, Juan M. ,  KAHN, Johanna ,  LIU, Bryan Yanwen ,  LONDON, Elisha ,  NGUYEN, Minhthy ,  RICHARDS, James David ,  RUDOLPH, Colin

IPC: A23L33/00 ,  A23L33/115 ,  A23L33/19 ,  A23L33/20

CPC classification number: A23L33/15 ,  A23L33/115 ,  A23L33/12 ,  A23L33/17 ,  A23L33/19 ,  A23L33/40 ,  A23V2002/00

Abstract: A method for enhancing cognitive development in a pediatric subject involving administering to the subject a nutritional composition which includes up to 7 g/100 Kcal of a fat or lipid; up to 5 g/100 Kcal of a protein or protein equivalent source; 0.06 g/100 Kcal to 1.5 g/100 Kcal of an enriched milk product; 5 mg/100 Kcal to 90 mg/100 Kcal of a source of long chain polyunsaturated fatty acid; and 0.015 g/100 Kcal to 1.5 g/100 Kcal of a prebiotic.

Abstract translation: 一种用于增强儿科受试者认知发展的方法，包括对受试者施用包含高达7g / 100Kcal脂肪或脂质的营养组合物; 高达5 g / 100 Kcal的蛋白质或蛋白质当量来源; 0.06g / 100Kcal至1.5g / 100Kcal的富集奶制品; 5 mg / 100 Kcal至90 mg / 100 Kcal长链多不饱和脂肪酸源; 和0.015g / 100Kcal至1.5g / 100Kcal的益生元。