-
公开(公告)号：WO2014150563A1
公开(公告)日：2014-09-25
申请号：PCT/US2014/023624
申请日：2014-03-11
Applicant: MJN U.S. HOLDINGS LLC
Inventor： HONDMANN, Dirk, , VAN TOL, Eric A.F. , GROSS, Gabriele , SCHOEMAKER, Marieke H. , LAMBERS, Teartse Tim
CPC classification number: A61K38/018 , A23J3/344 , A23L33/18 , A23L33/40 , A23V2002/00 , A61K31/202 , A61K45/06 , A23V2200/326 , A23V2200/332 , A23V2250/1862 , A23V2250/1868 , A23V2250/28 , A23V2250/54246 , A23V2250/55
Abstract: The present disclosure provides a method for activating adiponectin by administering a composition comprising peptides selected from a casein hydrolysate. Such a composition may reduce risk of heart attack and help in maintaining healthy weight. Preferably, the hydrolysate consists of peptides with a molecular weight of more than 500 Da.
Abstract translation: 本公开提供了通过施用包含选自酪蛋白水解产物的肽的组合物来激活脂联素的方法。 这样的组合物可以降低心脏病发作的风险并有助于保持体重。 优选地，水解产物由分子量大于500Da的肽组成。
-
Patent Agency Ranking2.发明申请NUTRITIONAL COMPOSITIONS COMPRISING LACTOBACILLUS RHAMNOSUS GG, AS WELL AS DIETARY BUTYRATE AND/OR A COMPOUND FOR STIMULATING FORMATION OF ENDOGENOUS BUTYRATE 审中-公开包含乳酸乳杆菌GG和营养丁酸盐和/或促进内源丁酸盐形成的化合物的营养组合物
公开(公告)号：WO2017083068A1
公开(公告)日：2017-05-18
申请号：PCT/US2016/057644
申请日：2016-10-19
Applicant: MJN U.S. HOLDINGS LLC
Inventor： LAMBERS, Teartse Tim , VAN TOL, Eric A.F. , GONZALEZ, Juan M.
CPC classification number: A23L33/10 , A23L33/12 , A23L33/135 , A23L33/18 , A23L33/19 , A23L33/21 , A23V2002/00 , A23Y2220/00 , A23V2200/30 , A23V2200/304 , A23V2200/32 , A23V2200/3202 , A23V2200/3204 , A23V2250/00 , A23V2250/1884 , A23V2250/284 , A23V2250/5116 , A23V2250/54246 , A23V2250/55 , A23Y2220/73
Abstract: Provided are nutritional compositions comprising a combination of the probiotic Lactobacillus rhamnosus GG, dietary butyrate and/or a component for stimulating endogenous butyrate production, e.g. the combination of polydextrose and galactooligosaccharides, in the human gut. Further disclosed are methods of accelerating tolerance to cow's milk in a pediatric subject by providing said nutritional compositions to a target subject.
Abstract translation: 提供营养组合物，其包含益生菌鼠李糖乳杆菌GG，饮食丁酸盐和/或用于刺激内源性丁酸盐产生的组分（例如， 聚葡萄糖和低聚半乳糖的组合，在人类肠道中。 还公开了通过向目标对象提供所述营养组合物来加速儿科患者对牛奶的耐受性的方法。
-
3.发明申请NUTRITIONAL COMPOSITIONS FOR PROMOTING GUT BARRIER FUNCTION AND AMELIORATING VISCERAL PAIN 审中-公开促进肠屏障功能和消除内脏痛的营养组合物
公开(公告)号：WO2017078907A1
公开(公告)日：2017-05-11
申请号：PCT/US2016/056207
申请日：2016-10-10
Applicant: MJN U.S. HOLDINGS LLC
Inventor： ZHONG, Yan , LAMBERS, Teartse Tim , GROSS, Gabriele , MANURUNG, Sarmauli , VAN TOL, Eric A.F. , WAWORUNTU, Rosaline
IPC: A23L33/00 , A61K35/747 , A23L33/135
CPC classification number: A61K35/747 , A23L29/065 , A23L33/135 , A23L33/40 , A23V2002/00 , A23Y2220/73 , A61K38/40 , A61K2035/115 , A61K2300/00
Abstract: The present disclosure is directed to methods for i) promoting gut regeneration, ii) promoting gut maturation and/or adaptation, iii) supporting gut barrier resistance and/or iv) protecting gut barrier function in a pediatric subject comprising administering to the pediatric subject a composition comprising an effective amount of a soluble mediator preparation derived from a late-exponential growth phase of a probiotic batch-cultivation process, such as Lactobacillus rhamnosus GG (LGG). The present methods advantageously provide the gut-protection benefits of LGG soluble mediators without introducing live bacterial culture to individuals with impaired gut barrier function. In some embodiments, the pediatric subject has impaired gut barrier function and/or short bowel syndrome. The present disclosure in other embodiments, directed methods for reducing visceral pain in a pediatric subject comprising administering to the pediatric subject a composition comprising an effective amount of a soluble mediator preparation from a late-exponential growth phase of a probiotic batch-cultivation process, such as LGG.
Abstract translation: 本公开涉及用于i）促进肠再生，ii）促进肠成熟和/或适应，iii）支持肠屏障耐受性和/或iv）保护儿科中的肠屏障功能的方法 包括向儿科对象施用包含有效量的衍生自益生菌分批培养过程的指数生长后期阶段的可溶性介质制剂（例如鼠李糖乳杆菌GG（LGG））的组合物。 本发明方法有利地提供LGG可溶性介质的肠道保护益处，而不会将活细菌培养物引入具有受损肠功能障碍的个体。 在一些实施方案中，儿科对象的肠道屏障功能和/或短肠综合征受损。 在其它实施方案中，本公开内容的用于减少儿科患者内脏疼痛的定向方法包括向儿科患者给药包含有效量的来自益生菌批培养过程的指数生长期后期的可溶性介质制剂的组合物，例如 作为LGG。
-
4.发明申请NUTRITIONAL COMPOSITION CONTAINING A PEPTIDE COMPONENT WITH ADIPONECTIN SIMULATING PROPERTIES AND USES THEREOF 审中-公开含有肽组分与ADIPONECTIN模拟性质的营养组合物及其用途
公开(公告)号：WO2014150557A1
公开(公告)日：2014-09-25
申请号：PCT/US2014/023600
申请日：2014-03-11
Applicant: MJN U.S. HOLDINGS LLC
Inventor： HONDMANN, Dirk , VAN TOL, Eric A.F. , GROSS, Gabriele , SCHOEMAKER, Marieke H. , LAMBERS, Teartse Tim
CPC classification number: A61K38/08 , A23J3/344 , A23L33/12 , A23L33/135 , A23L33/18 , A23L33/40 , A23V2002/00 , A61K35/745 , A61K35/747 , A61K38/018 , A61K38/07 , A23V2200/332 , A23V2250/55
Abstract: The present disclosure relates to nutritional compositions including a protein equivalent source that includes a peptide component comprising selected peptides. The protein equivalent source may further include intact protein, hydrolyzed protein, including partially hydrolyzed protein, or combinations thereof. The disclosure further relates to methods of promoting healthy body weight in a target subject by stimulating adiponectin levels by providing the nutritional compositions disclosed herein to a target subject, which includes a pediatric subject.
Abstract translation: 本公开涉及包括蛋白质当量源的营养组合物，其包含包含选定肽的肽组分。 蛋白质当量源可以进一步包括完整蛋白质，水解蛋白质，包括部分水解的蛋白质，或其组合。 本公开还涉及通过将本文公开的营养组合物提供给包括儿科受试者的目标受试者来刺激脂联素水平来在目标受试者中促进健康体重的方法。
-
公开(公告)号：WO2017083067A1
公开(公告)日：2017-05-18
申请号：PCT/US2016/057641
申请日：2016-10-19
Applicant: MJN U.S. Holdings LLC
Inventor： GONZALEZ, Juan M. , LAMBERS, Teartse Tim. , VAN TOL, Eric A.F.
CPC classification number: A23L33/10 , A23L33/12 , A23L33/135 , A23L33/18 , A23L33/19 , A23L33/21 , A23V2002/00 , A23Y2220/00 , A23V2200/30 , A23V2200/304 , A23V2200/32 , A23V2200/3202 , A23V2200/3204 , A23V2250/00 , A23V2250/1884 , A23V2250/284 , A23V2250/5116 , A23V2250/54246 , A23V2250/55 , A23Y2220/73
Abstract: Provided are nutritional compositions containing dietary butyrate. The nutritional compositions may exhibit additive or synergistic beneticial health effects when consumed. Further provided are methods for improving the shelf-stability and/or organoleptic properties of nutritional compositions including dietary butyrate.
Abstract translation: 提供了含有膳食丁酸盐的营养组合物。 当食用时营养组合物可表现出加和或协同的特殊健康效应。 进一步提供了用于改善营养组合物的储存稳定性和/或感官特性的方法，所述营养组合物包括丁酸盐饮食。
-
6.发明申请
公开(公告)号：WO2016073126A1
公开(公告)日：2016-05-12
申请号：PCT/US2015/054383
申请日：2015-10-07
Applicant: MJN U.S. HOLDINGS LLC
Inventor： VAN TOL, Eric A.F. , SCHOEMAKER, Marieke H. , GROSS, Gabriele , LAMBERS, Teartse Tim , WIELINGA, Peter , KLEEMANN, Robert
IPC: A23L33/18 , A23L33/135 , A23L33/115
CPC classification number: A61K38/08 , A23L33/115 , A23L33/12 , A23L33/135 , A23L33/18 , A23V2002/00 , A23Y2220/73 , A61K31/202 , A61K35/747 , A61K38/06 , A61K2035/115 , A23V2200/328 , A23V2200/332 , A23V2250/186 , A23V2250/1862 , A23V2250/1868 , A23V2250/1882 , A23V2250/54 , A23V2250/55
Abstract: The present disclosure relates to nutritional supplement including a peptide component. The nutritional supplement further includes a source of long-chain polyunsaturated fatty acids and Lactobacillus rhamnosus GG. The disclosure further relates to methods of protecting against obesity and its related metabolic disorders and inflammatory diseases in a target subject by providing the nutritional supplement(s) disclosed herein to a target subject, which includes a pediatric subject.
Abstract translation: 本公开涉及包含肽组分的营养补充剂。 营养补充剂还包括长链多不饱和脂肪酸源和鼠李糖乳杆菌GG。 本公开进一步涉及通过将本文公开的营养补充剂提供给包括儿科受试者的目标受试者来防止目标受试者中的肥胖及其相关的代谢紊乱和炎性疾病的方法。
-
-
-
-
-
Search Results
6
records
(took 0.021 seconds)
