公开(公告)号：WO2020243368A1

公开(公告)日：2020-12-03

申请号：PCT/US2020/035001

申请日：2020-05-28

申请人： MONSANTO TECHNOLOGY LLC

发明人： CARGILL, Edward James ,  EUDY, Douglas Michael ,  KOURANOV, Andrei Y. ,  LAWRENCE, Richard Joseph ,  SLEWINSKI, Thomas L. ,  SHULTZ, Randy ,  TO, PokChun Jennnifer ,  YANG, Samuel Sukhwan ,  ZHANG, Yuanji

IPC分类号： C12N15/113 ,  A61K48/00 ,  C12N5/10 ,  C07K14/415 ,  C12N15/102 ,  C12N15/1137 ,  C12N15/8213 ,  C12N15/8216 ,  C12N15/8218 ,  C12N15/8223 ,  C12N15/8226 ,  C12N15/8261 ,  C12N15/8262 ,  C12N15/8286 ,  C12N15/8297 ,  C12N15/902 ,  C12N2310/11 ,  C12N2310/127 ,  C12N2310/141 ,  C12N2310/20 ,  C12N2320/34 ,  C12N9/0071 ,  C12N9/22 ,  A40

摘要： The present disclosure provides methods and compositions for generating dominant alleles using targeted editing techniques. Also provided are modified chromosomes, cells, tissues, and plants comprising modified dominant allele.