公开(公告)号：WO2010030630A1

公开(公告)日：2010-03-18

申请号：PCT/US2009/056313

申请日：2009-09-09

Applicant: NEW YORK UNIVERSITY

Inventor： TEIXEIRA, Christina C. ,  ALIKHANI, Mani

IPC: A61C5/00

CPC classification number: A61C17/20 ,  A61C8/0006 ,  A61H13/00 ,  A61H23/02

Abstract: The present invention relates to a method for increasing bone growth in teeth and/or other craniofacial regions of a subject. This method includes administering to the jaw and/or teeth of the subject a mechanical vibration having a frequency of 10 to 1000 Hz with an acceleration peak of 0.1 to 2.00 g and that can produce a low magnitude strain of 1 to 50 microstrain in the jaw and/or teeth. The present invention also relates to devices that deliver high frequency, low magnitude force to the teeth.

Abstract translation: 本发明涉及一种用于增加受试者的牙齿和/或其他颅面部区域中的骨生长的方法。 该方法包括向受试者的颌和/或牙齿施用频率为10至1000Hz的机械振动，加速峰值为0.1至2.00g，并且可产生钳口中1至50微应变的低幅值应变 和/或牙齿。 本发明还涉及向牙齿传递高频，低幅度力的装置。

公开(公告)号：WO2017156294A2

公开(公告)日：2017-09-14

申请号：PCT/US2017/021608

申请日：2017-03-09

Applicant: NEW YORK UNIVERSITY

Inventor： ALIKHANI, Mani ,  TEIXEIRA, Cristina ,  OLIVEIRA, Serafim ,  SANGSUWON, Chinapa

IPC: A61C7/14

Abstract: The present invention relates to an orthodontic bracket device and, in particular, a bracket that provides for enhanced adjustability such that a force or moment may be activated by the orthodontic bracket device. The bracket may comprise a housing portion having a first channel extending from a first end to a second end through the housing portion. The first channel is configured to slidably receive an arch wire therethrough. The bracket also comprises a body portion configured to be received within the housing portion. The housing portion is configured to rotatably mount to the body portion about a first axis and a second axis. The first axis may be in an apico-coronal direction of the tooth, and the second axis may be in a buccopalatal direction of the tooth. The bracket further comprises a base portion configured to attach to a surface of the tooth. The body portion is configured to slidably mount on the base portion along the apico- coronal direction of the tooth.

Abstract translation: 本发明涉及一种正畸托架装置，特别涉及一种提供增强的可调节性的托架，使得正畸托架装置可以启动力或力矩。 支架可以包括壳体部分，该壳体部分具有第一通道，该第一通道从第一端延伸穿过壳体部分到达第二端。 第一通道被构造成可滑动地接收穿过其中的弓丝。 支架还包括构造成容纳在壳体部分内的主体部分。 壳体部分构造成围绕第一轴线和第二轴线可旋转地安装到本体部分。 第一轴线可以处于牙齿的尖顶 - 冠状方向，并且第二轴线可以处于牙齿的颊骨方向。 支架还包括构造成附接到牙齿的表面的基部。 主体部分被配置为沿着牙齿的尖顶方向可滑动地安装在基部上。

公开(公告)号：WO2019036609A1

公开(公告)日：2019-02-21

申请号：PCT/US2018/046900

申请日：2018-08-17

Applicant: NEW YORK UNIVERSITY

Inventor： ALIKHANI, Mani ,  TEIXEIRA, Cristina ,  SANGSUWON, Chinapa ,  ALANSARI, Sarah ,  OLIVEIRA, Serafim ,  ROQUE, Candido

IPC: A61M37/00

CPC classification number: A61M37/0015 ,  A46B11/002 ,  A61B17/205 ,  A61B17/3472 ,  A61C19/06 ,  A61C19/063 ,  A61M2037/0023

Abstract: The present invention relates to a device. The device includes an elongate handle having a proximal end and a distal end; a head portion extending from the proximal end of the elongate handle, the head portion having a first interior-facing surface and an opposing second exterior-facing surface; and a plurality of microneedles extending from, and perpendicular to, the first interior-facing surface of the head portion. Each of the plurality of microneedles has a base connected to the first interior-facing surface of the head portion and a free tip end. The present invention also relates to a method for stimulation of cortical bone formation using the device of the present invention.

公开(公告)号：WO2017156294A3

公开(公告)日：2017-09-14

申请号：PCT/US2017/021608

申请日：2017-03-09

Applicant: NEW YORK UNIVERSITY

Inventor： ALIKHANI, Mani ,  TEIXEIRA, Cristina ,  OLIVEIRA, Serafim ,  SANGSUWON, Chinapa

IPC: A61C7/12 ,  A61C7/28

Abstract: The present invention relates to an orthodontic bracket device and, in particular, a bracket that provides for enhanced adjustability such that a force or moment may be activated by the orthodontic bracket device. The bracket may comprise a housing portion having a first channel extending from a first end to a second end through the housing portion. The first channel is configured to slidably receive an arch wire therethrough. The bracket also comprises a body portion configured to be received within the housing portion. The housing portion is configured to rotatably mount to the body portion about a first axis and a second axis. The first axis may be in an apico-coronal direction of the tooth, and the second axis may be in a buccopalatal direction of the tooth. The bracket further comprises a base portion configured to attach to a surface of the tooth. The body portion is configured to slidably mount on the base portion along the apico- coronal direction of the tooth.

公开(公告)号：WO2018009848A1

公开(公告)日：2018-01-11

申请号：PCT/US2017/041170

申请日：2017-07-07

Applicant: NEW YORK UNIVERSITY

Inventor： ALIKHANI, Mani ,  TEIXEIRA, Cristina ,  OLIVEIRA, Serafim ,  SANGSUWON, Chinapa

IPC: A61C7/28 ,  A61C7/14 ,  A61C7/22 ,  A61C7/24 ,  A61C7/30 ,  F16H19/04

CPC classification number: A61C7/14 ,  A61C7/008 ,  A61C7/22 ,  A61C7/28 ,  A61C7/30 ,  F16H19/04

Abstract: An orthodontic device and, in particular, an orthodontic bracket that is slidable along a wire without external forces is provided. The device may include a first and second gear, each of which are independently movable between a locked position in which the gear is prevented from rotation, and a released configuration in which the gear extends into the channel to engage a wire received within the channel and is rotatable to move the device along the wire. The first gear may be rotatable to move the device in a first direction while the second gear may be rotatable to move the device in a second direction opposite the first direction. Thus, the first and second gears have the ability to move along the wire in short or long distances, as desired.

Abstract translation: 提供了一种正畸装置，特别是一种可在没有外力的情况下沿导线滑动的正畸托架。 该装置可以包括第一和第二齿轮，它们中的每一个都可以在防止齿轮旋转的锁定位置和齿轮延伸进入通道中以接合通道内容纳的金属丝的释放构型之间独立地移动，以及 是可旋转的以沿装置移动装置。 第一齿轮可以是可旋转的以沿第一方向移动装置，而第二齿轮可以是可旋转的以沿与第一方向相反的第二方向移动装置。 因此，第一和第二齿轮能够根据需要在短距离或长距离上沿着导线移动。

公开(公告)号：WO2011019382A1

公开(公告)日：2011-02-17

申请号：PCT/US2010/002202

申请日：2010-08-11

Applicant: NEW YORK UNIVERSITY ,  TEIXEIRA, Cristina, C. ,  ALIKHANI, Mani

Inventor： TEIXEIRA, Cristina, C. ,  ALIKHANI, Mani

IPC: A61C3/00

CPC classification number: A61C7/00 ,  A61B17/1604 ,  A61C3/00

Abstract: The present invention provides methods for moving a tooth to a desired position within a patient's mouth using orthodontics including perforating tissue in the oral cavity sufficient to induce an inflammatory response. The perforations may be made in any area of the maxilla or mandible, and any number of perforations may be made that are preferably 05 to 1 5 mm diameter, and preferably 1 to 3mm deep. The invention also provides a device that may be used in conjunction with slow-speed rotary instruments or with manual drivers for providing the perforations. The device has a drill that makes the perforations and a stop that prevents the drill from penetrating the jaw bone beyond a predetermined depth. The invention also provides a kit that supplies the professional with the necessary components in a sealed container to carry out the osteoperforations.

Abstract translation: 本发明提供了使用正畸治疗将牙齿移动到患者口腔内期望位置的方法，其包括在口腔中穿孔足以引起炎症反应的组织。 穿孔可以在上颌骨或下颌骨的任何区域中制造，并且可以制造任何数量的穿孔，其优选直径为直径为05至1mm，优选为1至3mm。 本发明还提供了一种可以与慢速旋转仪器一起使用的装置，或者与用于提供穿孔的手​​动驱动器一起使用的装置。 该装置具有钻孔，其使穿孔和阻止钻头穿过颚骨超过预定深度的止挡件。 本发明还提供了一种工具，其向专业人员提供必要的部件在密封容器中以进行骨形成。