公开(公告)号：WO2012058231A1

公开(公告)日：2012-05-03

申请号：PCT/US2011/057727

申请日：2011-10-25

Applicant: NXSTAGE MEDICAL, INC. ,  BURBANK, Jeffrey, H. ,  BRUGGER, James, M. ,  TURK, Joseph, E.

Inventor： BURBANK, Jeffrey, H. ,  BRUGGER, James, M. ,  TURK, Joseph, E.

IPC: A61M5/158

CPC classification number: A61M1/3659 ,  A61M1/3653 ,  A61M1/3656 ,  A61M1/3661 ,  A61M5/158 ,  A61M5/1582 ,  A61M5/3243 ,  A61M5/365 ,  A61M2005/1586 ,  A61M2005/1587 ,  A61M2005/1588 ,  A61M2005/3256 ,  A61M2207/00 ,  B29C65/48 ,  B29C66/1122 ,  B29C66/5221 ,  Y10T29/49879

Abstract: The disclosed subject matter includes a structure and method for making a dual-lumen needle from single lumen needles to take advantage of the much higher economies of scale. Variations include two needles joined by a flow junction and one needle and a single cannula joined by a flow junction. In addition disclosed are methods of using a dual-lumen needle in a two needle access for blood treatment is disclosed in which at least venous flow is provided through a dual-lumen needle with arterial flow just sufficient to provide air infiltration detection in the event of withdrawal of the dual-lumen needle.

Abstract translation: 所公开的主题包括用于从单腔针制造双腔针的结构和方法，以利用高得多的规模经济。 变化包括通过流动接头连接的两个针和一个针和通过流动接头连接的单个插管。 另外公开了在双针通路中使用双腔针进行血液处理的方法，其中至少通过具有动脉流的双腔针提供静脉血流，足以在发生下列情况时提供空气渗透检测 撤回双腔针。

公开(公告)号：WO2016057982A1

公开(公告)日：2016-04-14

申请号：PCT/US2015/055031

申请日：2015-10-09

Applicant: NXSTAGE MEDICAL, INC.

Inventor： BURBANK, Jeffrey, H. ,  TREU, Dennis, M. ,  RUBERY, Daniel, J. ,  NEWELL, Scott, W. ,  BRUGGER, James, M. ,  SCHNELL, William, J. ,  WEIGEL, William ,  WHITE, Steve ,  WYETH, Mark, T. ,  JAMES, Jerome ,  DESOUZA, David ,  TURK, Joseph, E. ,  CASEY, Garrett

IPC: A61M1/14 ,  A61M1/34

CPC classification number: A61M1/1605 ,  A61M1/14 ,  A61M1/1613 ,  A61M1/1615 ,  A61M1/1647 ,  A61M1/165 ,  A61M1/34 ,  A61M1/3403 ,  A61M1/341 ,  A61M1/3434 ,  A61M1/3437 ,  A61M1/3441 ,  A61M1/3444 ,  A61M1/3448 ,  A61M1/3607 ,  A61M1/3609 ,  A61M1/3635 ,  A61M2205/058 ,  A61M2205/15 ,  A61M2205/3331 ,  A61M2205/3334 ,  A61M2205/3341 ,  A61M2205/3351 ,  A61M2205/3355 ,  A61M2205/3365 ,  A61M2205/3368 ,  A61M2205/502 ,  A61M2205/702

Abstract: The disclosed subject matter relates to extracorporeal blood processing or other processing of fluids. Volumetric fluid balance, a required element of many such processes, may be achieved with multiple pumps or other proportioning or balancing devices which are to some extent independent of each other. This need may arise in treatments that involve multiple fluids. Safe and secure mechanisms to ensure fluid balance in such systems are described.

Abstract translation: 所公开的主题涉及流体的体外血液处理或其它处理。 体积流体平衡是许多这样的过程的必需元件，可以通过在一定程度上彼此独立的多个泵或其它配比或平衡装置来实现。 这种需要可能在涉及多种流体的治疗中出现。 描述了确保这种系统中的液体平衡的安全和可靠的机构。

公开(公告)号：WO2014160370A1

公开(公告)日：2014-10-02

申请号：PCT/US2014/026410

申请日：2014-03-13

Applicant: NXSTAGE MEDICAL, INC.

Inventor： WEIGEL, William, K. ,  TURK, Joseph, E. ,  STANGE, Jan ,  TREU, Dennis, M

IPC: A61M1/14

CPC classification number: A61M1/3663 ,  A61M1/1603 ,  A61M1/1633 ,  A61M1/1645 ,  A61M1/1676 ,  A61M1/1694 ,  A61M1/3403 ,  A61M1/3417 ,  A61M1/3679

Abstract: Methods, systems, and devices are disclosed, embodiments of which provide single pass dialysis to remove water and uremic toxins is performed simultaneously with the albumin dialysis therapy by passing the albumin solution through a dialysis filter which dialyses it before the solution is returned to the cycler. In embodiments, the single pass dialysis stage is upstream of the albumin filtering stage.

Abstract translation: 公开了方法，系统和装置，其实施方案提供单次透析以除去水和尿毒症毒素，其与白蛋白透析治疗同时进行，通过使白蛋白溶液通过透析过滤器，在透析过滤器将溶液返回到循环仪 。 在实施方案中，单次透析阶段在白蛋白过滤阶段的上游。