MICROARRAY SLIDES THAT ENHANCE FLUORESCENT SIGNALS VIA PLASMONIC INTERACTION
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    发明申请
    MICROARRAY SLIDES THAT ENHANCE FLUORESCENT SIGNALS VIA PLASMONIC INTERACTION 审中-公开
    通过等离子体相互作用增强荧光信号的微光滑块

    公开(公告)号:WO2016148951A1

    公开(公告)日:2016-09-22

    申请号:PCT/US2016/021140

    申请日:2016-03-07

    申请人: PLASMONIX, INC.

    发明人: BAUMGOLD, Jesse

    摘要: The invention describes generating and use of a multi-layer plasmonic slide, wherein the plasmonic slide comprises at least 6 layers of metallic nanoparticles that can enhance the detection of fluorescent signals and wherein the plasmonic slide can be printed as a microarray of any size. The microarray containing the plasmonic slide can further be printed with a protein, a glycan, or an antibody. The multi-layer plasmonic slide is capable of detecting proteins, polynucleotides, and/or glycans at orders of magnitude lower concentration than non-plasmonic substrates.

    摘要翻译: 本发明描述了生成和使用多层等离子体激动载玻片,其中等离子体激动载玻片包括至少6层金属纳米颗粒,其可以增强荧光信号的检测,并且其中等离子体激动载玻片可以作为任何尺寸的微阵列印刷。 含有等离子体激动载玻片的微阵列还可以用蛋白质,聚糖或抗体印刷。 多层等离子体激动载玻片能够检测比非等离子体激元底物更低浓度的蛋白质,多核苷酸和/或聚糖。