公开(公告)号：WO2020191301A1

公开(公告)日：2020-09-24

申请号：PCT/US2020/023882

申请日：2020-03-20

Applicant: PULSE BIOSCIENCES, INC.

Inventor： EBBERS, Edward, A. ,  UECKER, Darrin, R. ,  NUCCITELLI, Richard, L.

IPC: A61B18/14 ,  A61B17/00 ,  A61N5/06 ,  A61B18/20 ,  A61N7/02 ,  A61N1/04

Abstract: Described herein are methods and apparatuses for the application of electric energy treatment(s) to skin tissue to alter pigmentation, and in particular to remove a tattoo. These methods and apparatuses may deliver pulsed electrical energy having a pulse duration in submicrosecond pulse range to provide high-field strength pulses that may effectively release tattoo ink and allow removal of tattoo ink regardless of ink color or composition.

公开(公告)号：WO2019032474A1

公开(公告)日：2019-02-14

申请号：PCT/US2018/045433

申请日：2018-08-06

Applicant: PULSE BIOSCIENCES, INC.

Inventor： DANITZ, David, J. ,  HINMAN, Cameron, D. ,  EBBERS, Edward ,  NUCCITELLI, Richard, L. ,  MOSS, Kevin, L. ,  UECKER, Darrin, R.

IPC: A61B18/14 ,  A61N1/04 ,  A61N1/32

Abstract: Methods and apparatuses for treating a tissue with an electric treatment by rotating a pattern of electrodes partway through a treatment is disclosed. Also described herein are methods and apparatuses to treat tissue, including treating skin disorders, by selectively de-nucleating epidermal cells without provoking a significant inflammatory response, e.g., without increasing the density of leukocytes in the treated skin, and without affecting the non-cellular components of the dermis.