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    METHOD FOR ADDING AN APPARENT NON-SIGNAL LINE TO A RAPID DIAGNOSTIC ASSAY
    1.
    发明申请
    METHOD FOR ADDING AN APPARENT NON-SIGNAL LINE TO A RAPID DIAGNOSTIC ASSAY 审中-公开
    一种将非信号线附加到快速诊断方法

    公开(公告)号：WO03023371A9

    公开(公告)日：2003-09-04

    申请号：PCT/US0228846

    申请日：2002-09-10

    Applicant: QUIDEL CORP

    Inventor： JEROME JEREMY ,  DAQUIPA MARK ,  JACONO BRUCE ,  BOEHRINGER HANS ,  LAMBOTTE PAUL ,  LAWRENCE PAUL J

    IPC: G01N21/86 ,  G01N33/543 ,  G01N33/558 ,  G01N21/00 ,  C12M1/34

    CPC classification number: G01N21/8483 ,  B01L3/5023 ,  G01N33/54386 ,  G01N33/558 ,  Y10S435/805 ,  Y10S435/823 ,  Y10S436/807 ,  Y10S436/81 ,  Y10S436/823 ,  Y10T436/25125

    Abstract: A test device and method for determining the presence or absence of one or more analytes in a fluid sample, the test device including a support (14) or member bearing a mark (46)thereon, and a matrix (18) or member containing a capture zone (40). In operation, an observation area (38) in the test device becomes transparent, thereby allowing the user to view a mark that is present on a support that is disposed beneath the observation area. Typically, the mark on the underlying support is configured as a minus (-) sign. In the absence of analyte in the sample, the test device presents a negative result as a minus (-) signal. In the presence of analyte in the sample, however, the mark operates in concert with a perpendicular test line on the observation area to present a positive result as a plus (+) signal that is visible to the user.

    Abstract translation: 一种用于确定流体样品中一种或多种分析物的存在或不存在的测试装置和方法，所述测试装置包括支撑件（14）或在其上具有标记（46）的构件，以及基体（18）或包含 捕获区（40）。 在操作中，测试装置中的观察区域（38）变得透明，从而允许用户观看存在于设置在观察区域下方的支撑体上的标记。 通常，底层支持上的标记被配置为减号（ - ）。 在样品中没有分析物的情况下，测试装置呈负值（-1）信号。 然而，在样品中存在分析物的情况下，标记与观察区域上的垂直测试线一致，以将正的结果呈现为使用者可见的加号（+）信号。

    ICONIC COLORIMETRIC TEST DEVICE WITH REDUCED SUSCEPTIBILITY TO FALSE POSITIVE AND FALSE NEGATIVE READINGS
    3.
    发明申请
    ICONIC COLORIMETRIC TEST DEVICE WITH REDUCED SUSCEPTIBILITY TO FALSE POSITIVE AND FALSE NEGATIVE READINGS 审中-公开
    具有降低可靠性以假阳性和虚假负面阅读的图标彩色测试设备

    公开(公告)号：WO2005029068A2

    公开(公告)日：2005-03-31

    申请号：PCT/US2004030564

    申请日：2004-09-17

    Applicant: QUIDEL CORP ,  LAWRENCE PAUL J ,  CHAUDHURI AULENA

    Inventor： LAWRENCE PAUL J ,  CHAUDHURI AULENA

    IPC: G01N33/00 ,  G01N33/48 ,  G01N33/52

    CPC classification number: G01N33/521 ,  Y10T436/17 ,  Y10T436/173845

    Abstract: Laminated test devices in which positive results are detected by the appearance of a symbol on the surface of the device due to a color change in an indicator in the device are improved by placing the indicator lamina on one side of a light-transmissive substrate sheet and a pigment lamina on the other side, the indicator lamina forming the icon and the pigment lamina forming the background, the pigment being the color of the indicator prior to the color change. This arrangement reduces false positive readings by obscuring the outlines of the symbol prior to the color change. False negative readings are reduced by further changes in the arrangement of the laminae.

    Abstract translation: 通过将装置中的指示器的颜色变化由于装置的指示器的颜色变化而由装置的表面上的符号的外观检测出正面结果的层叠试验装置通过将指示剂层放置在透光性基板的一侧而得到改善， 在另一侧的颜料层，形成图标的指示剂层和形成背景的颜料层，颜料是在颜色变化之前指示剂的颜色。 这种布置通过在颜色变化之前遮蔽符号的轮廓来减少假阳性读数。 通过薄片布置的进一步变化减少假阴性读数。

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