专利检索 ap:("RENSSELAER POLYTECH INST" OR "SALERNO JOHN C" OR "SMITH SUSAN M E") AND inv:"SMITH SUSAN M E" 第 1 页

1.

发明申请
CALMODULIN INDEPENDENT ACTIVATION OF NITRIC OXIDE SYNTHASE 审中-公开
标题翻译：硝酸氧化酶合成酶的钙调素独立活化

公开(公告)号：WO2005115407A3

公开(公告)日：2009-04-09

申请号：PCT/US2005018379

申请日：2005-05-25

申请人： RENSSELAER POLYTECH INST , SALERNO JOHN C , SMITH SUSAN M E

发明人： SALERNO JOHN C , SMITH SUSAN M E

IPC分类号： A61K31/675 , A61K31/7052

CPC分类号： A61K31/7052 , A61K31/675 , G01N2333/90245 , G01N2500/02

摘要： Methods for activation of a constitutive nitric oxide synthase are described, as are agents which activate a constitutive nitric oxide synthase (e.g., NADPH analogs), methods of identifying such agents, and methods of treatment of diseases or conditions associated with nitric oxide production by a constitutive nitric oxide synthase, by administering an agent which activates the constitutive nitric oxide synthase.

摘要翻译： 描述了激活组成型一氧化氮合成酶的方法，活化组成型一氧化氮合酶（例如NADPH类似物）的试剂，鉴定这些试剂的方法，以及治疗与一氧化氮产生有关的疾病或病症的方法通过施用激活组成型一氧化氮合酶的试剂来构成一氧化氮合酶。

2.

发明申请
CALMODULIN INDEPENDENT ACTIVATION OF NITRIC OXIDE SYNTHASE BY NADPH ANALOGS 审中-公开
标题翻译： NADPH类似物对钙调素一氧化氮合酶的独立活化作用

公开(公告)号：WO2004044194A3

公开(公告)日：2004-07-08

申请号：PCT/US0335570

申请日：2003-11-07

申请人： RENSSELAER POLYTECH INST , SALERNO JOHN C , SMITH SUSAN M E

发明人： SALERNO JOHN C , SMITH SUSAN M E

IPC分类号： A61K31/7052 , A61K38/00 , C12N9/02

CPC分类号： C12N9/0075 , A61K31/7052 , A61K38/00 , C12Y114/13039

摘要： Methods for activation of a constitutive nitric oxide synthase are described, as are agents which activate a constitutive nitric oxide synthase (e.g., NADPH analogs), methods of identifying such agents, and methods of treatment of diseases or conditions associated with nitric oxide production by a constitutive nitric oxide synthase, by administering an agent which activates the constitutive nitric oxide synthase.

摘要翻译： 描述了活化组成型一氧化氮合酶的方法，以及活化组成型一氧化氮合酶（例如NADPH类似物）的试剂，鉴定此类试剂的方法以及治疗与由一氧化氮产生一氧化氮相关的疾病或病症的方法组成型一氧化氮合酶，通过施用激活组成性一氧化氮合酶的试剂。