公开(公告)号：WO2011029889A1

公开(公告)日：2011-03-17

申请号：PCT/EP2010/063266

申请日：2010-09-09

Applicant: SENSA BUES AB ,  PALMSKOG, Göran ,  BECK, Olof

Inventor： PALMSKOG, Göran ,  BECK, Olof

IPC: G01N33/497 ,  A61B5/097 ,  H01J49/04

CPC classification number: G01N21/658 ,  A61B5/082 ,  A61B5/412 ,  G01J3/44 ,  G01N33/497

Abstract: A portable system (10) is disclosed for collecting a sample from exhaled breath of a subject. Drug substance in the exhaled breath are detected or determined. The sample is collected for further analysis using mass-spectroscopy. The system comprises a sampling unit (14) and a housing (12) arranged to hold the sampling unit (14), the sampling unit (14) is adapted to collect non-volatile and volatile compounds of the at least one drug substance from the exhaled breath from the subject. The housing (12) has at least one inlet (15) for the subject to exhale into the housing (12) to the sampling unit (14) and at least one outlet (16) for the exhaled breath to exit through.

Abstract translation: 公开了一种便携式系统（10），用于从受试者的呼出气中收集样品。 检测或确定呼出气中的药物。 收集样品以进行质谱分析。 该系统包括一个采样单元（14）和一个布置成保持采样单元（14）的壳体（12），采样单元（14）适用于从该采样单元（14）收集至少一种药物的非挥发性和挥发性化合物 从主题呼出呼吸。 壳体（12）具有至少一个入口（15），用于受试者呼出到采样单元（14）的壳体（12）和用于呼出的呼吸的至少一个出口（16）通过。

公开(公告)号：WO2011029888A1

公开(公告)日：2011-03-17

申请号：PCT/EP2010/063265

申请日：2010-09-09

Applicant: SENSA BUES AB ,  PALMSKOG, Göran ,  BECK, Olof ,  ANDERSSON, Per Ola

Inventor： PALMSKOG, Göran ,  BECK, Olof ,  ANDERSSON, Per Ola

IPC: G01N21/65 ,  G01N33/497

CPC classification number: G01N21/658 ,  A61B5/082 ,  A61B5/412 ,  G01J3/44 ,  G01N33/497

Abstract: A sensor for detecting a drug substance (15) from exhaled breath of a subject in-situ. Its collecting surface has a Surface Enhanced Raman Spectroscopy (SERS)-active layer (14) of a SERS-active material. The collecting surface is arranged as an outer surface of a waveguide (12) for contact with exhaled breath, such that at least traces of said drug substance (15) in said exhaled breath can contact said SERS-active layer for read-out of a Raman shift spectrum.

Abstract translation: 一种用于从现场呼出的呼吸气体检测药物（15）的传感器。 其收集表面具有SERS活性材料的表面增强拉曼光谱（SERS）活性层（14）。 收集表面被布置为用于与呼出的呼吸接触的波导（12）的外表面，使得所述呼出的呼吸中的至少痕量的所述药物（15）可以接触所述SERS活性层以读出 拉曼位移谱。

公开(公告)号：WO2006033635A1

公开(公告)日：2006-03-30

申请号：PCT/SE2005/001411

申请日：2005-09-23

Applicant: ARTEMA MEDICAL AB ,  PALMSKOG, Göran

Inventor： PALMSKOG, Göran

IPC: G01N21/25

CPC classification number: G01N21/3504 ,  G01J3/10 ,  G01N21/314

Abstract: An arrangement for determining concentration of substances in a fluid comprising a light source (2) for generating primary light pulses within a wavelength interval, a light pulse splitter (5) adapted to split up the primary light pulses into a predetermined number of secondary light pulses to be transmitted through the fluid, the secondary light pulses being separated in time as well as wavelength to be differently absorbed upon passage of the fluid depending on the concentration of the substances, a detector (13) for detecting intensity of the differently absorbed secondary light pulses, and a comparator (14) for comparing the intensities of the differently absorbed secondary light pulses with different reference intensities corresponding to different substances to thereby determine the concentration of the substances in the fluid.

Abstract translation: 一种用于确定流体中物质浓度的装置，包括用于在波长间隔内产生初级光脉冲的光源（2），适于将初级光脉冲分裂成预定数量的次级光脉冲的光脉冲分离器（5） 通过流体传输，二次光脉冲在时间和波长上被分离，以根据物质的浓度在流体通过时被不同地吸收;检测器（13），用于检测不同吸收的次级光的强度 脉冲和比较器（14），用于将不同吸收的次级光脉冲的强度与对应于不同物质的不同参考强度进行比较，从而确定流体中的物质的浓度。