METHOD FOR DIAGNOSING AND DISTINGUISHING TRAUMATIC BRAIN INJURY AND DIAGNOSTIC DEVICES FOR USE THEREIN
    1.
    发明申请
    METHOD FOR DIAGNOSING AND DISTINGUISHING TRAUMATIC BRAIN INJURY AND DIAGNOSTIC DEVICES FOR USE THEREIN 审中-公开
    诊断和鉴别创伤性脑损伤的方法和用于其中的诊断装置

    公开(公告)号:WO03019181A3

    公开(公告)日:2003-09-04

    申请号:PCT/CA0201299

    申请日:2002-08-23

    CPC classification number: G01N33/6896 A61B6/501 G01N2333/988

    Abstract: Methods of implementing rapid assessment of patients presenting with brain trauma injury in humans are provided. These methods comprise presenting a subject possibly suffering from traumatic brain injury, selecting one or more markers to detect injury, tracking evolution of injury by tracking marker concentration over time, and determining repetitive injury by the correlation of molecular weight markers appearing over the course of time.

    Abstract translation: 提供了对人类脑外伤损伤患者进行快速评估的方法。 这些方法包括呈现可能患有创伤性脑损伤的受试者,选择一个或多个标记物以检测损伤,通过追踪标记物浓度随时间追踪损伤的进展,并通过随时间推移出现的分子量标记物的相关性确定重复性损伤 。

    METHOD FOR MONITORING AND VALIDATING STRESS INDUCTION OF DISEASE STATE
    2.
    发明申请
    METHOD FOR MONITORING AND VALIDATING STRESS INDUCTION OF DISEASE STATE 审中-公开
    监测和确定疾病状态诱发应激的方法

    公开(公告)号:WO02088709A3

    公开(公告)日:2003-05-01

    申请号:PCT/CA0200621

    申请日:2002-04-29

    CPC classification number: C40B30/04 G01N33/6845

    Abstract: The present invention provides a biochemically-based methodology for ascertaining the presence and/or verifying the historical release of biopolymers, which have been shown to be indicative of a disease state or are predictive of the development of said disease state.

    Abstract translation: 本发明提供了用于确定存在和/或验证生物聚合物的历史释放的基于生物化学的方法,其已被证明是指示疾病状态或预示出所述疾病状态的发展。

    CONJUNCTIVE ANALYSIS OF BIOLOGICAL MARKER EXPRESSION FOR DIAGNOSING ORGAN FAILURE
    3.
    发明申请
    CONJUNCTIVE ANALYSIS OF BIOLOGICAL MARKER EXPRESSION FOR DIAGNOSING ORGAN FAILURE 审中-公开
    用于诊断有机体失败的生物标记表达的连续分析

    公开(公告)号:WO03020123A2

    公开(公告)日:2003-03-13

    申请号:PCT/CA0201298

    申请日:2002-08-23

    Abstract: A diagnostic tool is disclosed for accurately and rapidly diagnosing the condition of an ailing organ. Although applicable to numerous organ and organ systems, this application particularly illustrates the concept of conjunctive marker utilization as it relates to diagnosing and distinguishing congestive heart failure. The invention particularly relates to the conjunctive utilization of cardiac Troponin I (cTn-I) and natriuretic peptide, e.g. ANP, pro-ANP, BNP, pro-BNP and CNP as a retrospective tool for diagnosing the underlying mechanism of heart failure and as a prospective analytical device for monitoring disease progression and efficacy of therapeutic agents.

    Abstract translation: 公开了一种诊断工具,用于准确快速地诊断有害器官的状况。 虽然适用于许多器官和器官系统,但是该应用特别说明了与诊断和区分充血性心力衰竭有关的联合标记利用的概念。 本发明特别涉及心肌肌钙蛋白I(cTn-1)和利尿钠肽的联合利用。 ANP,pro-ANP,BNP,pro-BNP和CNP作为诊断心力衰竭潜在机制的回顾性工具,以及作为监测治疗剂疾病进展和功效的前瞻性分析仪器。

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