公开(公告)号：WO2012016215A3

公开(公告)日：2012-02-02

申请号：PCT/US2011/046015

申请日：2011-07-29

Applicant: TAXON BIOSCIENCES, INC. ,  ASHBY, Matthew ,  DIMSTER-DENK, Dago

Inventor： ASHBY, Matthew ,  DIMSTER-DENK, Dago

IPC: C12N15/11 ,  C12Q1/68

Abstract: In alternative embodiments, the invention provides products of manufacture and compositions, e.g., nucleic acid probes, for use as identifying agents or indicators to detect the presence of a hydrocarbon in a sample, e.g., in marine sediments, muds, sands and the like, or in a solution, e.g., an aqueous solution, such as a production water, fresh water, underground water or seawater. In alternative embodiments, the invention provides compositions, e.g., nucleic acid probes or primers or primer pairs, for use as sensors and/or identifying agents to detect the presence of a hydrocarbon in a sample (e.g., in fresh water, underground water or seawater, or a marine mud, sand or sediment), where the presence of the hydrocarbon indicates e.g., the presence of a subsurface oil, petroleum or gas accumulation or deposit. In alternative embodiments, the invention provides compositions and methods for use as tools for offshore oil exploration activities.

公开(公告)号：WO2011159924A3

公开(公告)日：2011-12-22

申请号：PCT/US2011/040742

申请日：2011-06-16

Applicant: TAXON BIOSCIENCES, INC. ,  ASHBY, Matthew ,  WOOD, Ladonna ,  LIDSTRÖM, Ulrika ,  CLARKE, Christine ,  GOULD, Alison ,  STRAPOC, Dariusz ,  LAMBO, Adewale ,  HUIZINGA, Bradley, James

Inventor： ASHBY, Matthew ,  WOOD, Ladonna ,  LIDSTRÖM, Ulrika ,  CLARKE, Christine ,  GOULD, Alison ,  STRAPOC, Dariusz ,  LAMBO, Adewale ,  HUIZINGA, Bradley, James

IPC: C12Q1/68 ,  C12Q1/02 ,  C12N15/31 ,  C12N1/20 ,  C12P7/00

Abstract: This invention generally relates to natural gas and methylotrophic energy generation, bio-generated fuels and microbiology. In alternative embodiments, the invention provides nutrient amendments and microbial compositions, e.g., consortia, that are both specifically optimized to stimulate methanogenesis, or for "methylotrophic" or other conversions. In alternative embodiments, the invention provides methods to develop nutrient amendments and microbial compositions that are both specifically optimized to stimulate methanogenesis in a given reservoir. The invention also provides methods for the evaluation of potentially damaging biomass formation and scale precipitation resulting from the addition of nutrient amendments. In other embodiments, the invention provides methods for simulating biogas in sub-surface conditions using a computational model.

公开(公告)号：WO2014005094A1

公开(公告)日：2014-01-03

申请号：PCT/US2013/048719

申请日：2013-06-28

Applicant: TAXON BIOSCIENCES, INC.

Inventor： KUNIN, Victor ,  ASHBY, Matthew ,  SCHERER, Stewart ,  PATIN, Nasstasia

IPC: C12Q1/04 ,  C12Q1/68 ,  C12N1/20 ,  G06F17/00

CPC classification number: C12Q1/689 ,  C12Q1/04 ,  C12Q1/6809 ,  G06F19/18 ,  G06F19/26 ,  C12Q2535/122 ,  C12Q2537/165

Abstract: In alternative embodiments, the invention provides computational algorithms, computer programs, software and other methods, systems and products of manufacture (e.g., computers, devices or apparatus) for identifying members of microbial communities, their abundance and distribution from amplicon sequence data, and comparing microbial communities and consortia. In alternative embodiments, the invention provides computer- implemented methods comprising a subset of, substantially all, or all of the steps as set forth in the flow chart of Figure 1, Figure 3 or Figure 4. In alternative embodiments, the invention provides methods for identification of consortia, optionally followed by construction of artificial microbial consortia from pure strains or enrichment cultures.

Abstract translation: 在替代实施例中，本发明提供用于识别微生物群落成员的计算算法，计算机程序，软件和其他方法，系统和产品（例如计算机，设备或设备），其丰度和从扩增子序列数据的分布，以及比较 微生物群落和财团。 在替代实施例中，本发明提供计算机实现的方法，其包括图1，图3或图4的流程图中阐述的步骤的子集，基本上全部或全部。在替代实施例中，本发明提供了用于 识别联合体，随后可以从纯菌株或富集培养物中构建人造微生物菌群。