公开(公告)号：WO2014005094A1

公开(公告)日：2014-01-03

申请号：PCT/US2013/048719

申请日：2013-06-28

Applicant: TAXON BIOSCIENCES, INC.

Inventor： KUNIN, Victor ,  ASHBY, Matthew ,  SCHERER, Stewart ,  PATIN, Nasstasia

IPC: C12Q1/04 ,  C12Q1/68 ,  C12N1/20 ,  G06F17/00

CPC classification number: C12Q1/689 ,  C12Q1/04 ,  C12Q1/6809 ,  G06F19/18 ,  G06F19/26 ,  C12Q2535/122 ,  C12Q2537/165

Abstract: In alternative embodiments, the invention provides computational algorithms, computer programs, software and other methods, systems and products of manufacture (e.g., computers, devices or apparatus) for identifying members of microbial communities, their abundance and distribution from amplicon sequence data, and comparing microbial communities and consortia. In alternative embodiments, the invention provides computer- implemented methods comprising a subset of, substantially all, or all of the steps as set forth in the flow chart of Figure 1, Figure 3 or Figure 4. In alternative embodiments, the invention provides methods for identification of consortia, optionally followed by construction of artificial microbial consortia from pure strains or enrichment cultures.

Abstract translation: 在替代实施例中，本发明提供用于识别微生物群落成员的计算算法，计算机程序，软件和其他方法，系统和产品（例如计算机，设备或设备），其丰度和从扩增子序列数据的分布，以及比较 微生物群落和财团。 在替代实施例中，本发明提供计算机实现的方法，其包括图1，图3或图4的流程图中阐述的步骤的子集，基本上全部或全部。在替代实施例中，本发明提供了用于 识别联合体，随后可以从纯菌株或富集培养物中构建人造微生物菌群。