公开(公告)号：WO2012173754A1

公开(公告)日：2012-12-20

申请号：PCT/US2012/039119

申请日：2012-05-23

申请人： TERUMO BCT, INC. ,  HOLMES, Brian M.

发明人： HOLMES, Brian M.

IPC分类号： A61M1/36 ,  B04B5/04

CPC分类号： A61M1/3693 ,  A61M1/30 ,  A61M1/303 ,  A61M1/308 ,  A61M1/3696 ,  B04B5/0442 ,  B04B2005/045 ,  B04B2005/0471

摘要： A disposable blood separation set and a centrifugal blood processing system comprising a blood processing chamber adapted to be mounted on a rotor of a centrifuge; a frustro-conical cell separation chamber in fluid communication with the processing chamber, the cell separation chamber having an inlet, and outlet and a side tap outlet adjacent the inlet. The inlet may protrude into the cell separation chamber forming a circumferential well surrounding the protruding inlet. The side tap outlet may connect to the well. The set and system comprise means for selectively drawing fluid from either the outlet or the side tap outlet.

摘要翻译： 一种一次性血液分离装置和离心血液处理系统，包括适于安装在离心机的转子上的血液处理室; 与处理室流体连通的截头圆锥形细胞分离室，细胞分离室具有入口，出口和邻近入口的侧出口出口。 入口可以突出到细胞分离室中，形成围绕突出入口的周向井。 侧面出水口可以连接到井。 该组件和系统包括用于从出口或侧面出口出口选择性地抽取流体的装置。

公开(公告)号：WO2018195508A3

公开(公告)日：2018-10-25

申请号：PCT/US2018/028695

申请日：2018-04-20

申请人： TERUMO BCT, INC.

发明人： FELT, Thomas J. ,  HLAVINKA, Dennis J. ,  HOLMES, Brian M. ,  O'BRIEN, Peter ,  POLODNA, Taylor

IPC分类号： A61M1/38 ,  A61M1/36 ,  A61M1/02

摘要： Described are embodiments that include devices for separating components from blood. Embodiments may involve the separation of plasma from whole blood. Also described are embodiments that include methods and devices for positioning portions, e.g., loops, of disposables in medical devices. Embodiments may involve use of surfaces for automatically guiding loops to position them into a predetermined position.

公开(公告)号：WO2018195508A2

公开(公告)日：2018-10-25

申请号：PCT/US2018/028695

申请日：2018-04-20

申请人： TERUMO BCT, INC.

发明人： FELT, Thomas J. ,  HLAVINKA, Dennis J. ,  HOLMES, Brian M. ,  O'BRIEN, Peter ,  POLODNA, Taylor

IPC分类号： A61M1/38 ,  A61M1/36 ,  A61M1/02

摘要： Described are embodiments that include methods and devices for separating components from multi-component fluids. Embodiments may involve use of separation vessels and movement of components into and out of separation vessels through ports. Embodiments may involve the separation of plasma from whole blood. Also described are embodiments that include methods and devices for positioning portions, e.g., loops, of disposables in medical devices. Embodiments may involve use of surfaces for automatically guiding loops to position them into a predetermined position.

公开(公告)号：WO2011071773A1

公开(公告)日：2011-06-16

申请号：PCT/US2010/058917

申请日：2010-12-03

申请人： CARIDIANBCT, INC. ,  KOLENBRANDER, Jeremy P. ,  HOLMES, Brian M. ,  FELT, Thomas J. ,  LADTKOW, James R.

发明人： KOLENBRANDER, Jeremy P. ,  HOLMES, Brian M. ,  FELT, Thomas J. ,  LADTKOW, James R.

IPC分类号： A61M1/36 ,  B04B5/04

CPC分类号： G01N21/51 ,  A61M1/3693 ,  A61M1/3696 ,  A61M2202/0439 ,  A61M2205/3306 ,  B04B13/00 ,  B04B2013/006 ,  G01N2035/00495 ,  A61M2202/0071

摘要： A centrifugal blood separation system comprising a rotor (21), a light source (12), an optical sensor (16), a control system (34), a separation vessel (20), and an optical cell (180) on the separation vessel. The optical cell has a first extraction port (182) extending radially outwardly into the optical cell, a red blood cell extraction port (186) downstream from the first extraction port and extending into the optical cell beyond the first extraction port; and a dam (192) between said first extraction port and said red blood cell extraction port, having an upper edge and a lower edge, wherein the first extraction port and the red cell extraction port are radially between the upper edge and the lower edge of the dam. Also, a first extraction port having a bore (216) having a first diameter, a lumen (212) having a second diameter smaller than the first diameter, and a frustro- conical passageway (214) coupling the bore to the lumen.

摘要翻译： 一种离心血液分离系统，包括转子（21），光源（12），光学传感器（16），控制系统（34），分离容器（20）和分离器 船只。 所述光学单元具有径向向外延伸到所述光学单元中的第一提取端口（182），所述第一提取端口下游并延伸到所述光学单元之外的红细胞提取端口（186）超出所述第一提取端口; 和位于所述第一提取口和所述红细胞提取口之间的坝（192），具有上边缘和下边缘，其中第一提取口和红细胞提取口径向地位于上边缘和下边缘之间 大坝 此外，具有第一直径的孔（216）和具有小于第一直径的第二直径的内腔（212）的第一抽取端口和将孔与腔连接的截头锥形通道（214）。

公开(公告)号：WO2008079611A1

公开(公告)日：2008-07-03

申请号：PCT/US2007/086454

申请日：2007-12-05

申请人： GAMBRO BCT, INC. ,  HOLMES, Brian M.

发明人： HOLMES, Brian M.

IPC分类号： A61M1/36

CPC分类号： A61M1/3693 ,  A61M1/3692 ,  A61M1/3695 ,  A61M1/3698 ,  C12M47/02

摘要： Method and apparatus for separating a volume of whole blood into at least a plasma component and a red blood cell component comprising centrifuging a separation bag (1) containing a volume of whole blood so as to separate therein at least a first component comprising plasma and a second component comprising red blood cells; transferring the first component into a plasma component bag (4) during centrifugation of the separation bag (1); transferring into the separation bag (1) a volume of wash solution from a wash solution bag (3) during centrifugation of the separation bag (1); mixing the volume of wash solution with the second component; centrifuging the separation bag (1) so as to separate therein a washed red blood cell component and a supernatant component; and transferring the supernatant component into a waste bag (2; 3) during centrifugation of the separation bag (1).

摘要翻译： 将全血体积分成至少血浆成分和红细胞成分的方法和装置，包括离心含有一定体积的全血的分离袋（1），以至少分离其中包含等离子体和 第二组分包含红细胞; 在离心分离袋（1）期间将第一组分转移到等离子体组分袋（4）中; 在分离袋（1）的离心过程中将洗涤溶液袋（3）的一定量的洗涤溶液转移到分离袋（1）中; 将洗涤溶液的体积与第二组分混合; 离心分离袋（1）以在其中分离洗涤的红细胞成分和上清液组分; 并在分离袋（1）的离心过程中将上清组分转移到废物袋（2; 3）中。