IMAGING PROBE FOR ANGIOGENIC ACTIVITY IN PULMONARY ARTERIAL HYPERTENSION
    1.
    发明申请
    IMAGING PROBE FOR ANGIOGENIC ACTIVITY IN PULMONARY ARTERIAL HYPERTENSION 审中-公开
    影像学检查在肺动脉高压中的作用

    公开(公告)号:WO2017079473A1

    公开(公告)日:2017-05-11

    申请号:PCT/US2016/060383

    申请日:2016-11-03

    CPC classification number: A61K51/103 A61B6/032 A61B6/037 C07K16/22

    Abstract: A method of detecting a disease associated with pulmonary vascular remodeling. The method includes administering a radioisotope-conjugated antibody against vascular endothelial growth factor (VEGF). The method further includes imaging said antibody using positron emission tomography (PET), computed tomography (CT), or magnetic resonance imaging (MIR). Retention of said antibody reflects vascular remodeling.

    Abstract translation: 检测与肺血管重塑有关的疾病的方法。 该方法包括施用抗血管内皮生长因子(VEGF)的放射性同位素缀合的抗体。 该方法还包括使用正电子发射断层摄影术(PET),计算机断层摄影术(CT)或磁共振成像(MIR)对所述抗体进行成像。 所述抗体的保留反映血管重塑。

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