公开(公告)号：WO2014158940A1

公开(公告)日：2014-10-02

申请号：PCT/US2014/021011

申请日：2014-03-06

Applicant: THE CLEVELAND CLINIC FOUNDATION

Inventor： GRESKOVICH, John, Jr

IPC: A61N5/10 ,  A61M25/00 ,  A61M25/10

CPC classification number: A61N5/1002 ,  A61N2005/1003 ,  A61N2005/1005 ,  A61N2005/1094

Abstract: A system for delivery of radiation to a target portion of a native tissue is provided. The system includes a catheter having a main catheter body. The main catheter body includes an outer catheter surface and an inner catheter surface that defines a longitudinally oriented lumen. The lumen extends between longitudinally spaced proximal and distal catheter face surfaces extending laterally between the inner and outer catheter surfaces. A sheath covers at least a portion of the outer catheter surface. The sheath includes a tapered portion protruding substantially longitudinally distally from a portion of the distal catheter face surface. A plurality of tubes extends through the lumen towards the distal catheter face surface. Each tube of the plurality of tubes is configured to selectively guide exposure of a radiation source to the target portion of the native tissue.

Abstract translation: 提供了用于将辐射递送到天然组织的目标部分的系统。 该系统包括具有主导管主体的导管。 主导管主体包括外导管表面和限定纵向定向内腔的内导管表面。 内腔在纵向间隔开的在导管内表面和外导管表面之间横向延伸的近端和远端导管面表面延伸。 护套覆盖外导管表面的至少一部分。 护套包括从远端导管面表面的一部分基本上纵向远端突出的锥形部分。 多个管延伸穿过内腔朝向远端导管面表面。 多个管中的每个管被配置成选择性地引导辐射源暴露于天然组织的目标部分。