公开(公告)号：WO2013032984A1

公开(公告)日：2013-03-07

申请号：PCT/US2012/052451

申请日：2012-08-27

申请人： THE GENERAL HOSPITAL CORPORATION ,  REDMOND, Robert, W. ,  YUN, Seok-Hyun

发明人： REDMOND, Robert, W. ,  YUN, Seok-Hyun

IPC分类号： A61N5/06 ,  A61B1/07 ,  G02B6/02

CPC分类号： A61N5/0601 ,  A61B1/00165 ,  A61B1/07 ,  A61N5/062 ,  A61N2005/063 ,  A61N2005/0643 ,  G02B6/0003 ,  G02B6/0036 ,  G02B6/02033

摘要： A system and method for establishing optical communication between the depths of the biological tissue, optionally exceeding 1 cm, and the ambient environment with the use of an optical waveguide device that includes biodegradable material. The waveguide device is configured to deliver light from the outside into the biological tissue and/or vice versa. The light delivered from the biological tissue is informative about the status of the tissue. A specific waveguide device includes a mesh of biodegradable optical waveguides, is configured for insertion into the tissue, and does not require to be removed from the tissue after the irradiation of the tissue has been accomplished.

摘要翻译： 一种利用包括可生物降解材料的光波导装置在生物组织的深度（可选地超过1cm）和周围环境之间建立光学通信的系统和方法。 波导装置被配置为将光从外部输送到生物组织和/或反之亦然。 从生物组织传递的光对组织的状态有信息。 具体的波导装置包括可生物降解的光波导的网格，被配置为插入到组织中，并且在组织的照射已经完成之后不需要从组织中移除。

公开(公告)号：WO2009137793A1

公开(公告)日：2009-11-12

申请号：PCT/US2009/043340

申请日：2009-05-08

申请人： THE GENERAL HOSPITAL CORPORATION ,  KOCHEVAR, Irene, E. ,  REDMOND, Robert, W. ,  O'NEILL, Anne, C. ,  RANDOLPH, Mark

发明人： KOCHEVAR, Irene, E. ,  REDMOND, Robert, W. ,  O'NEILL, Anne, C. ,  RANDOLPH, Mark

IPC分类号： A61B17/08

CPC分类号： A61B17/1128

摘要： The present invention relates to a field of biocompatible membranes, tubes and conduits which comprising a photosensitizer which is capable of being crosslinked to form a three dimensional structure which can be implanted into a subject to assist in tissue bonding and nerve maintenance and development. Methods of making such membranes, tubes and conduits and kits comprising them are also described.

摘要翻译： 本发明涉及生物相容性膜，管和导管领域，其包含能够交联以形成三维结构的光敏剂，该三维结构可被植入受试者以辅助组织粘合和神经维持和发育。 还描述了制造这种膜，管和导管以及包括它们的试剂盒的方法。

公开(公告)号：WO2014015274A1

公开(公告)日：2014-01-23

申请号：PCT/US2013/051333

申请日：2013-07-19

申请人： THE GENERAL HOSPITAL CORPORATION

发明人： AUSTEN, William, G. ,  MC CORMACK, Michael ,  REDMOND, Robert, W. ,  KOCHEVAR, Irene, E.

IPC分类号： A61L27/50 ,  A61L27/14 ,  A61N5/06 ,  A61F2/07

CPC分类号： A61F2/06 ,  A61K41/0057 ,  A61L27/3604 ,  A61L27/3633 ,  A61L27/50 ,  A61L27/505 ,  A61L27/54 ,  A61L31/005 ,  A61L31/14 ,  A61L31/16 ,  A61L2300/418 ,  A61L2300/424 ,  A61L2300/442 ,  A61L2400/18 ,  A61L2430/04 ,  A61L2430/22 ,  A61L2430/34 ,  A61N5/0601 ,  A61N5/0603 ,  A61N5/062 ,  A61N5/0624

摘要： Methods of tissue passivation are described herein for use in preserving normal tissue architecture, reducing post-surgical inflammation, and reducing or preventing the development of pathogenic collagen bundles and adhesions following surgical procedures (e.g., grafting, implanting).

摘要翻译： 组织钝化的方法在本文中描述用于保存正常组织结构，减少手术后炎症，以及减少或防止外科手术后的病原性胶原蛋白束和粘连的发展（例如移植，植入 ）。

公开(公告)号：WO2010065026A3

公开(公告)日：2010-06-10

申请号：PCT/US2008/078639

申请日：2008-10-02

申请人： THE GENERAL HOSPITAL CORPORATION ,  TEARNEY, Guillermo ,  BOUMA, Brett ,  REDMOND, Robert, W. ,  KOCHEVAR, Irene, E.

发明人： TEARNEY, Guillermo ,  BOUMA, Brett ,  REDMOND, Robert, W. ,  KOCHEVAR, Irene, E.

IPC分类号： A61B18/18

摘要： The exemplary embodiments of the present invention provides exemplary methods for adhering biological membranes to luminal anatomical structures using photosensitizing agents and electromagnetic energy. The exemplary embodiments of the present invention also provides method for stabilizing luminal anatomical structures. Further, exemplary embodiments of the present invention provide arrangements for coupling to a luminal anatomical structure.