公开(公告)号：WO2023036881A1

公开(公告)日：2023-03-16

申请号：PCT/EP2022/075018

申请日：2022-09-08

Applicant: TOFWERK AG

Inventor： GONIN, Marc

IPC: H01M10/05 ,  G01M3/00 ,  G01N27/00 ,  H01M10/42 ,  H01M50/10 ,  H01M50/20 ,  H01J49/00 ,  H01M10/48 ,  G01M3/20 ,  G01M3/22

Abstract: The invention relates to a method for detecting one or more leaks in a battery enclosure (101) of a battery (100), the battery (100) including at least one electrochemical cell (102) enclosed in the battery enclosure (101), or detecting one or more leaks in the at least one electrochemical cell (102) being in the battery enclosure (101) or separate from the battery enclosure (101). The method comprises the steps of obtaining gas, in particular air, from a surrounding of the battery (100) or from a surrounding of the at least one electrochemical cell (102) being in the battery enclosure (101) or separate from the battery enclosure (101), respectively, obtaining an analysis of the gas by analysing the gas with an analysis method and determining on the basis of the analysis whether the gas includes a signature of at least one constituent part of the at least one electrochemical cell (102), the signature indicating a presence of the at least one constituent part of the at least one electrochemical cell (102) in the gas. In case it is determined on the basis of the analysis that the gas includes the signature of the at least one constituent part of the at least one electrochemical cell (102), a leak in the battery enclosure (102) of the battery (100) or in the at least one electrochemical cell (102) being in the battery enclosure (101) or separate from the battery enclosure (101), respectively, is detected. In the analysis method, the gas is ionised by an ionisation source (31) with an ionisation method to ions and the ions are analysed in an analyser (32) by being separated according to one or more physical properties, wherein the ionisation source (31) is a chemical ionisation source and the ionisation method is a chemical ionisation method. The invention further relates to an apparatus (1) for detecting one or more leaks in a battery enclosure (101) of a battery (100) with the method according to the invention.

公开(公告)号：WO2019149903A1

公开(公告)日：2019-08-08

申请号：PCT/EP2019/052533

申请日：2019-02-01

Applicant: TOFWERK AG

Inventor： GONIN, Marc ,  LOPEZ-HILFIKER, Felipe ,  HUTTERLI, Manuel ,  ERB, Matthias ,  PFANDER, Marc

IPC: H01J49/04

Abstract: The invention relates to an autosampler (1) for obtaining mass spectra from a plurality of fluid samples, in particular gaseous samples. This autosampler (1) comprises a plurality of containers (2.1, 2.2, 2.3, 2.4, 2.5, 2.6) comprising sample sources (3.1, 3.2, 3.3, 3.4, 3.5, 3.6) providing the samples, wherein each one of the containers (2.1, 2.2, 2.3, 2.4, 2.5, 2.6) provides a docking port (4.1, 4.2, 4.3, 4.4, 4.5, 4.6) for being connected with a connector (5) for enabling access to an inside of the respective container (2.1, 2.2, 2.3, 2.4, 2.5, 2.6) via the connector (5) when the connector (5) is connected to the respective docking port (4.1, 4.2, 4.3, 4.4, 4.5, 4.6) in order to obtain the respective sample from the respective container (2.1, 2.2, 2.3, 2.4, 2.5, 2.6) via said connector (5). Thereby, the connector (5) is connectable to and detachable from each docking port (4.1, 4.2, 4.3, 4.4, 4.5, 4.6). The autosampler (1) further comprise an ionisation source (6) for ionising at least a part of the samples to ions, wherein the ionisation source (6) is fluidly coupled to the connector (5) for receiving the samples from the containers (2.1, 2.2, 2.3, 2.4, 2.5, 2.6) via the connector (5). Furthermore, the autosampler (1) comprises a mass analyser (7) for obtaining the mass spectra from the ions, the mass analyser (7) being fluidly coupled to the ionisation source (6) for receiving the ions from the ionisation source (6) for obtaining the mass spectra from the ions. The ionisation source (6) is moveable with the connector (5) within the autosampler (1) sequentially to each one of the plurality of said containers (2.1, 2.2, 2.3, 2.4, 2.5, 2.6) for connecting the connector (5) to the docking port (4.1, 4.2, 4.3, 4.4, 4.5, 4.6) of the respective container (2.1, 2.2, 2.3, 2.4, 2.5, 2.6) for collecting the sample from the respective container (2.1, 2.2, 2.3, 2.4, 2.5, 2.6) for ionising at least a part of the sample to ions and obtaining the mass spectra from the ions. Furthermore, the invention relates to a method for operating the autosampler (1).

公开(公告)号：WO2018046083A1

公开(公告)日：2018-03-15

申请号：PCT/EP2016/071120

申请日：2016-09-07

Applicant: TOFWERK AG

Inventor： LOPEZ-HILFIKER, Felipe ,  GONIN, Marc ,  CUBISON, Mike

IPC: H01J49/04 ,  H01J49/16 ,  G01N33/00

Abstract: The invention relates to an apparatus (1) and a method for analysing a chemical composition of aerosol particles. The apparatus (1) comprises an extractive electronspray ionisation source (2) for extracting components, in particular organic compounds, from the aerosol particles and for ionising the components to ions, and a mass analyser (3), in particular a time-of-flight mass analyser, for analysing the ions, the mass analyser (3) fluidly coupled to the extractive electronspray ionisation source (2). The method includes the steps of extracting components, in particular organic compounds, from the aerosol particles with an extractive electronspray ionisation source (2) and ionising the components with the extractive electronspray ionisation source (2) to ions, transferring the ions to a mass analyser (3), in particular a time-of-flight mass analyser, the mass analyser (3) being fluidly coupled to the extractive electronspray ionisation source (2), and analysing the ions with the mass analyser (3).

Abstract translation: 本发明涉及用于分析气溶胶颗粒的化学组成的设备（1）和方法。 该装置（1）包括用于从气溶胶颗粒中提取组分特别是有机化合物并用于将组分离子化的萃取电子喷射离子源（2），以及质量分析器（3），特别是时间 - 飞行质量分析器，用于分析离子，质量分析器（3）流体耦合到提取电子喷射离子源（2）。 该方法包括以下步骤：用萃取电子喷射离子源（2）从气溶胶粒子萃取组分，特别是有机化合物，并用萃取电子喷射离子源（2）将组分离子化成离子，将离子转移到质量分析仪 （3），特别是飞行时间质量分析器，所述质量分析器（3）流体耦合到所述提取电子喷射离子源（2），并且利用所述质量分析器（3）分析所述离子。

公开(公告)号：WO2018046619A1

公开(公告)日：2018-03-15

申请号：PCT/EP2017/072510

申请日：2017-09-07

Applicant: TOFWERK AG

Inventor： LOPEZ-HILFIKER, Felipe ,  GONIN, Marc ,  CUBISON, Mike

IPC: H01J49/04 ,  H01J49/16 ,  G01N33/00

Abstract: The invention relates to an apparatus (1) and a method for analysing a chemical composition of aerosol particles. The apparatus (1) comprises an extractive electronspray ionisation source (2) for extracting components, in particular organic compounds, from the aerosol particles and for ionising the components to ions, and a mass analyser (3), in particular a time of flight mass analyser, for analysing the ions, the mass analyser (3) fluidly coupled to the extractive electronspray ionisation source (2). The method includes the steps of extracting components, in particular organic compounds, from the aerosol particles with an extractive electronspray ionisation source (2) and ionising the components with the extractive electronspray ionisation source (2) to ions, transferring the ions to a mass analyser (3), in particular a time of flight mass analyser, the mass analyser (3) being fluidly coupled to the extractive electronspray ionisation source (2), and analysing the ions with the mass analyser (3).

Abstract translation: 本发明涉及用于分析气溶胶颗粒的化学组成的设备（1）和方法。 装置（1）包括用于从气溶胶颗粒中提取组分特别是有机化合物并用于将组分离子化的萃取电子喷射离子源（2），以及质量分析器（3），特别是飞行时间质量 分析器，用于分析离子，质量分析器（3）流体耦合到提取电子喷射离子源（2）。 该方法包括以下步骤：用萃取电子喷射离子源（2）从气溶胶粒子萃取组分，特别是有机化合物，并用萃取电子喷射离子源（2）将组分离子化成离子，将离子转移到质量分析仪 （3），特别是飞行时间质量分析器，质量分析器（3）流体耦合到提取电子喷射离子源（2），并用质量分析器（3）分析离子。

公开(公告)号：WO2016150875A1

公开(公告)日：2016-09-29

申请号：PCT/EP2016/056030

申请日：2016-03-18

Applicant: TOFWERK AG

Inventor： TANNER, Christian ,  TANNER, Martin ,  GONIN, Marc

IPC: H01J49/04 ,  H01J49/10

CPC classification number: H01J49/0463 ,  H01J49/0445 ,  H01J49/105

Abstract: An apparatus for mass spectrometry comprises a portion generator (10) for creating localized analyte portions in synchronization with trigger pulses, a transfer system (20) coupled to the portion generator (10) for transporting the localized analyte portions, a plasma ionizer unit (30) coupled to the transfer system (20) for atomizing, vaporizing and ionizing received analyte portions with plasma, a mass analyzer (41) coupled to the plasma ionizer unit (30) for analyzing received analyte portions, the mass analyzer (41) comprising at least one detector, and a data acquisition electronics (50) connected to the at least one detector for acquiring signals (43) generated by the at least one detector. The apparatus further includes a signal delay device (60) for receiving the trigger pulses (11) and delivering delayed signals (61) corresponding to the trigger pulses to account for a delay experienced by the particles to be analyzed between portion generation and detection.

Abstract translation: 用于质谱的装置包括用于与触发脉冲同步地产生局部分析物部分的部分发生器（10），耦合到用于传送局部分析物部分的部分发生器（10）的传送系统（20），等离子体离子发生器单元 ，其耦合到所述传输系统（20），用于用等离子体雾化，蒸发和电离所接收的分析物部分;质量分析器（41），其耦合到所述等离子体离子发生器单元（30），用于分析所接收的分析物部分，所述质量分析器（41） 至少一个检测器和连接到所述至少一个检测器的数据采集电子器件（50），用于获取由所述至少一个检测器产生的信号（43）。 该装置还包括用于接收触发脉冲（11）并传送与触发脉冲对应的延迟信号（61）的信号延迟装置（60），以解决在部分产生和检测之间待分析的颗粒所经历的延迟。

公开(公告)号：WO2016004542A8

公开(公告)日：2016-01-14

申请号：PCT/CH2015/000101

申请日：2015-07-09

Applicant: TOFWERK AG

Inventor： GONIN, Marc ,  ROHNER, Urs ,  TANNER, Christian ,  TANNER, Martin ,  KIMMEL, Joel

IPC: H01J49/00

Abstract: A device for mass spectrometry comprises an ionization source, a mass analyzer fluidly coupled to the ionization source and an electronic data acquisition system for processing signals provided by the mass analyzer. The electronic data acquisition system comprises at least one analog-to-digital converter ( 10) producing digitized data from the signals obtained from the mass analyzer and a fast processing unit (47) receiving the digitized data from said analog-to-digital converter ( 10). The fast processing (47) unit is programmed to continuously, in real time inspect the digitized data for events of interest measured by the mass spectrometer; and the electronic data acquisition system is programmed to forward (23) the digitized data representing mass spectra relating to events of interest for further analysis and to reject the digitized data representing mass spectra not relating to events of interest. The device allows for maintaining efficiency at high speed by eliminating all processing times (idle time in acquisition) for data segments that do not contain information about events.

Abstract translation: 用于质谱分析的装置包括电离源，与电离源流体耦合的质量分析器以及用于处理由质量分析器提供的信号的电子数据采集系统。 该电子数据采集系统包括至少一个模数转换器（10），其从由质量分析器获得的信号中产生数字化数据，以及快速处理单元（47），其接收来自所述模数转换器的数字化数据 10）。 快速处理（47）单元被编程为连续地实时检查由质谱仪测量的感兴趣事件的数字化数据; 并且电子数据采集系统被编程为将表示与感兴趣事件相关的质谱的数字化数据转发（23）以用于进一步分析并且拒绝表示与感兴趣事件无关的质谱的数字化数据。 该设备通过消除不包含有关事件信息的数据段的所有处理时间（采集空闲时间），可以高速保持效率。