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公开(公告)号：WO2016200775A1
公开(公告)日：2016-12-15
申请号：PCT/US2016/036157
申请日：2016-06-07
Applicant: TOKITAE LLC
Inventor： CHOU, Fong-Li , ECKHOFF, Philip A. , FOWLER, Lawrence Morgan , LIU, Shieng , NATARAJAN, Krishnan , PETERSON, Nels R. , WOOD, Lowell L., Jr.
CPC classification number: A61J1/16 , A61J1/1406 , A61J2205/30 , B65B5/045 , B65B5/06 , B65B5/067 , B65B31/00 , B65B51/10 , B65B51/146 , B65B61/04 , B65B63/04 , B65B2220/16
Abstract: Methods and devices are described for packaging a multi-monodose container including covering a molded structure with a hermetically-sealable overwrap, the molded structure including a first portion and a second portion, the first portion including a row of interconnected monodose pharmaceutical vials, each of the interconnected monodose pharmaceutical vials enclosing a dose of at least one pharmaceutical agent, the second portion affixed to the first portion and including a textured surface pattern positioned to direct gas flow between the first portion and a region adjacent to the second portion; evacuating at least a portion of air from around the molded structure, the evacuated air at least partially flowing over the textured surface pattern of the second portion; forming a hermetic seal around the row of interconnected monodose pharmaceutical vials; and separating the second portion of the molded structure from the first portion of the molded structure.
Abstract translation: 描述了用于包装多单体容器的方法和装置，包括用可密封的外包装覆盖模制结构，所述模制结构包括第一部分和第二部分，所述第一部分包括一排互连的单糖药物小瓶，每个 所述相互连接的单糖药瓶包围剂量的至少一种药剂，所述第二部分固定在所述第一部分上，并且包括纹理表面图案，其被定位成引导所述第一部分与邻近所述第二部分的区域之间的气流; 从模制结构周围抽空至少一部分空气，抽空的空气至少部分地流过第二部分的纹理表面图案; 围绕相互连接的单糖药瓶的一排形成气密密封; 以及将模制结构的第二部分与模制结构的第一部分分开。
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公开(公告)号：WO2017100408A1
公开(公告)日：2017-06-15
申请号：PCT/US2016/065534
申请日：2016-12-08
Applicant: TOKITAE LLC
Inventor： CHOU, Fong-Li , ECKHOFF, Philip A. , FOWLER, Lawrence Morgan , LIU, Shieng , NATARAJAN, Krishnan , PETERSON, Nels R. , WOOD, Lowell L., Jr.
CPC classification number: A61J1/18 , A61J1/067 , A61J1/1481 , A61J2200/70 , A61J2200/72 , B65B5/06 , B65B31/048 , B65B63/04
Abstract: Methods are described for packaging a foldable container including covering a multi-monodose container in an expanded configuration with a hermetically-sealable overwrap, the multi-monodose container including a row of interconnected monodose pharmaceutical vials, each of the monodose pharmaceutical vials enclosing at least one pharmaceutical agent, the interconnected monodose pharmaceutical vials connected to one another by one or more articulating joints sufficiently flexible to form a folded configuration of the multi-monodose container; exerting a force on at least one of the monodose pharmaceutical vials; bending the one or more articulating joints to form the folded configuration of the multi-monodose container in response to the exerted force; and sealing the hermetically-sealable overwrap to form a hermetic seal around the folded configuration of the multi-monodose container.
Abstract translation: 描述了用于包装可折叠容器的方法，所述方法包括用可密封外包装覆盖处于展开构型的多单一剂量容器，所述多单一剂量容器包括一排相互连接的单剂药品小瓶，每一个 所述单剂药物小瓶包封至少一种药剂，所述互连的单剂药剂小瓶通过一个或多个铰接接头相互连接，所述一个或多个铰接接头足够柔性以形成所述多单剂容器的折叠构造; 对至少一个单剂量药瓶施加作用力; 响应于所施加的力而弯曲所述一个或多个铰接接头以形成所述多单剂容器的折叠构造; 并且密封可密封的外包裹物以围绕多单体容器的折叠构型形成气密密封。
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公开(公告)号：WO2016200771A1
公开(公告)日：2016-12-15
申请号：PCT/US2016/036151
申请日：2016-06-07
Applicant: TOKITAE LLC
Inventor： CHOU, Fong-Li , ECKHOFF, Philip, A. , FOWLER, Lawrence, Morgan , LIU, Shieng , NATARAJAN, Krishnan , PETERSON, Nels, R. , WOOD, Lowell, L., Jr.
CPC classification number: A61J1/16 , A61J1/1406 , A61J1/1412 , A61J1/18 , A61J2200/70 , A61J2200/72 , A61J2205/30
Abstract: Multi-monodose containers are described including a row of at least two vials, a first vial connected to an adjacent second vial through an articulating joint, the articulating joint sufficiently flexible to reversibly mate a planar outer surface of the first vial with a planar outer surface of the adjacent second vial; wherein the row of the at least two vials is configured to form a first rectangular packing cross-sectional area in an expanded configuration and configured to form a second rectangular packing cross-sectional area in a folded configuration, the second rectangular packing cross-sectional area smaller than the first rectangular packing cross-sectional area.
Abstract translation: 描述了包含一行至少两个小瓶的多单容器容器，通过铰接接头连接到相邻的第二小瓶的第一小瓶，所述铰接接头足够柔软以使第一小瓶的平面外表面与平面外表面 的相邻第二小瓶; 其中所述至少两个小瓶的所述行被配置为形成膨胀构型中的第一矩形填充横截面积并且构造成在折叠构型中形成第二矩形填充横截面积，所述第二矩形填充横截面积 小于第一矩形填料横截面积。
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公开(公告)号：WO2015195736A1
公开(公告)日：2015-12-23
申请号：PCT/US2015/036129
申请日：2015-06-17
Applicant: TOKITAE LLC
Inventor： BOOMGARD, John , CHOU, Fong-Li , ECKHOFF, Philip A. , LARUSSON, Fridrik , SHIENG, Liu , NATARAJAN, Krishnan , PETERSON, Nels R. , WOOD, Lowell L., Jr.
IPC: A61J1/00
CPC classification number: A61J1/16 , A61J1/065 , A61J1/1406 , A61J1/1412 , A61J2205/10 , A61J2205/30 , A61J2205/60 , B65D1/095 , B65D21/0201
Abstract: In some embodiments, an affixed group of pharmaceutical vials with frangible connectors includes: a plurality of pharmaceutical vials arranged as a group of pharmaceutical vials, each of the plurality of pharmaceutical vials shaped and positioned to minimize a total volume of the group of pharmaceutical vials, each of the pharmaceutical vials including at least one external side with a surface configured to reversibly mate with a corresponding external side and a surface of an adjacent pharmaceutical vial; and a plurality of frangible connectors, wherein at least one frangible connector is affixed to the surface of at least two of the plurality of pharmaceutical vials within the group of pharmaceutical vials, and at least one frangible connector is affixed to each of the plurality of pharmaceutical vials.
Abstract translation: 在一些实施方案中，具有易碎连接器的固定的药物小瓶组包括：多个药物小瓶，其布置成一组药物小瓶，所述多个药物小瓶中的每一个成形并定位成使得该组药瓶的总体积最小化， 每个药瓶包括至少一个外表面，其表面被配置为可逆地与相应的药物瓶的相应外侧和表面配合; 以及多个易碎连接器，其中至少一个易碎连接器固定到药物小瓶组内的多个药物小瓶中的至少两个的表面上，并且至少一个易碎连接器固定到多个药物 小瓶。
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