公开(公告)号：WO2014144685A3

公开(公告)日：2014-12-04

申请号：PCT/US2014029201

申请日：2014-03-14

Applicant: UNIV CALIFORNIA

Inventor： RAY ANANDASANKAR ,  BOYLE SEAN MICHAEL ,  MACWILLIAM DYAN ,  TAUXE GENEVIEVE MITCHELL

IPC: G01N33/00

CPC classification number: G01N33/5058 ,  A01N31/02 ,  A01N31/06 ,  A01N33/04 ,  A01N35/02 ,  A01N35/06 ,  A01N35/08 ,  A01N37/02 ,  A01N37/42 ,  A01N41/10 ,  A01N43/08 ,  A01N43/10 ,  A01N43/36 ,  G01N33/5032 ,  A01N35/04 ,  A01N43/78

Abstract: Provided herein are screening methods for identifying compounds for use as an arthropod repellent based on the masking or inhibition of the detection of the skin odor by a cpA neuron. Provided herein are also screening methods for identifying compounds for use as an arthropod attractant based on activation of the cpA neuron. Further provided are one or more compounds identified using the screening methods described herein, and compositions containing such compounds.

Abstract translation: 本文提供了基于通过cpA神经元掩蔽或抑制皮肤气味的检测来鉴定用作节肢动物驱避剂的化合物的筛选方法。 本文还提供了基于cpA神经元的活化鉴定用作节肢动物引诱剂的化合物的筛选方法。 还提供了一种或多种使用本文所述的筛选方法鉴定的化合物和含有这些化合物的组合物。