公开(公告)号：WO2021148064A1

公开(公告)日：2021-07-29

申请号：PCT/CZ2021/050007

申请日：2021-01-21

申请人： USTAV MAKROMOLEKULARNI CHEMIE AV CR, V.V.I. ,  BIOMOSAE

发明人： BENES, Hynek ,  BUJOK, Sonia ,  PARUZEL, Aleksandra ,  ZAJICOVA, Veronika ,  HNATKOVA, Tereza ,  BUSSCHER, Guuske Frederike ,  SCHMEETS, Alex Alois Joseph

IPC分类号： C08G18/16 ,  C08G18/18 ,  C08G18/24 ,  C08G18/32 ,  C08G18/40 ,  C08G18/42 ,  C08G18/64 ,  C08G18/66 ,  C08G18/73 ,  C08G18/79 ,  C08J9/08 ,  C12N1/20 ,  C12R1/00 ,  C12N9/42 ,  C12N11/093 ,  C12N9/24 ,  C08G18/165 ,  C08G18/1808 ,  C08G18/246 ,  C08G18/3218 ,  C08G18/4081 ,  C08G18/425 ,  C08G18/6484 ,  C08G18/6644 ,  C08G18/792 ,  C08G2110/0058 ,  C08G2230/00 ,  C08J2203/02 ,  C08J2300/16 ,  C08J2375/04 ,  C12N1/00 ,  C12N9/2411 ,  C12N9/2417 ,  C12N9/2442 ,  C12R2001/00

摘要： The present invention relates to a method of synthesis of a biodegradable polyurethane foam, comprising the following steps: i) mixing of at least one aliphatic isocyanate bearing at least two isocyanate groups with at least one saccharide in weight ratio of from 1:1 to 30:1 to form a saccharide-isocyanate precursor; ii) homogenization of the saccharide-isocyanate precursor from step i) with 20 to 70 % (w/w) of at least one biodegradable aliphatic polyester-ether polyol having molecular mass in the range of from 0 to 10 000 g/mol and hydroxyl number from 10 to 100 mgKOH/g, 1 to 5 % (w/w) of water, and 1 to 10 % (w/w) of at least one blowing agent other than water, related to the total weight of the resulting mixture; iii) foaming of the homogenized mixture from step ii) at the temperature of from 20 to 100 °C, resulting in the biodegradable polyurethane foam comprising incorporated saccharide. The invention further relates to a biodegradable polyurethane foam obtainable by this method, to a biodegradable polyurethane foam-based material for saccharide-cleaving enzyme production and to the use thereof.