公开(公告)号：WO2012034202A3

公开(公告)日：2012-12-27

申请号：PCT/BR2011000328

申请日：2011-09-13

Applicant: VALE SA ,  DONG JIE ,  XU MANQUI ,  SCHOLEY KENNETH ERWIN

Inventor： DONG JIE ,  XU MANQUI ,  SCHOLEY KENNETH ERWIN

IPC: C02F1/28 ,  B01D15/02 ,  B01D15/36 ,  C02F1/42 ,  C02F1/62 ,  C02F101/20 ,  C02F103/10 ,  C02F103/16 ,  C22B3/24

CPC classification number: C02F1/281 ,  B01J20/165 ,  B01J20/28059 ,  B01J20/2808 ,  B01J39/14 ,  C02F1/42 ,  C02F1/62 ,  C02F1/683 ,  C02F11/004 ,  C02F2001/425 ,  C02F2101/20 ,  C02F2101/22 ,  C02F2101/303 ,  C02F2101/38 ,  C02F2103/10 ,  C02F2103/16 ,  C02F2209/06 ,  C02F2301/024 ,  C02F2303/16 ,  C02F2303/18 ,  C22B3/24 ,  Y02P10/234

Abstract: The present invention refers to a method to remove organic chemicals and organometallic complexes (organic heavy metal complexes) using zeolite from process water or tailings streams of a mineral processing plant where diethylenetriamine (DETA) or triethylenetetramine (TETA) is used as a flotation reagent and DETA-metal complexes are found in process water or tailings streams. In a preferred embodiment, the process water or slurry tailings streams of a mineral processing plant containing DETA, DETA-metal complexes and residual heavy metals are contacted with natural zeolite. This can be carried out by adding the natural zeolite to the process streams (slurries) while mixing with a mechanical mixer to efficiently adsorb DETA, DETA-metal complexes and heavy metals from the process streams (slurries) on the zeolite. The loaded zeolite is then discarded with the flotation tailings.

Abstract translation: 本发明涉及使用二氧化三胺（DETA）或三亚乙基四胺（TETA）作为浮选试剂的矿物加工厂的工艺用水或尾矿料流中除去有机化学物质和有机金属络合物（有机重金属络合物）的方法， DETA金属络合物存在于工艺用水或尾矿料流中。 在优选的实施方案中，含有DETA，DETA-金属络合物和残余重金属的矿物加工设备的工艺水或浆料尾矿料流与天然沸石接触。 这可以通过将天然沸石加入到工艺流（浆料）中，同时与机械混合器混合，以有效地从沸石上的工艺流（浆料）中吸附DETA，DETA-金属络合物和重金属来进行。 然后用浮选尾矿弃去负载的沸石。

公开(公告)号：WO2012034202A8

公开(公告)日：2012-05-18

申请号：PCT/BR2011000328

申请日：2011-09-13

Applicant: VALE SA ,  DONG JIE ,  XU MANQUI ,  SCHOLEY KENNETH ERWIN

Inventor： DONG JIE ,  XU MANQUI ,  SCHOLEY KENNETH ERWIN

IPC: C02F1/42

CPC classification number: C02F1/281 ,  B01J20/165 ,  B01J20/28059 ,  B01J20/2808 ,  B01J39/14 ,  C02F1/42 ,  C02F1/62 ,  C02F1/683 ,  C02F11/004 ,  C02F2001/425 ,  C02F2101/20 ,  C02F2101/22 ,  C02F2101/303 ,  C02F2101/38 ,  C02F2103/10 ,  C02F2103/16 ,  C02F2209/06 ,  C02F2301/024 ,  C02F2303/16 ,  C02F2303/18 ,  C22B3/24 ,  Y02P10/234

Abstract: The present invention refers to a method to remove organic chemicals and organometallic complexes (organic heavy metal complexes) using zeolite from process water or tailings streams of a mineral processing plant where diethylenetriamine (DETA) or triethylenetetramine (TETA) is used as a flotation reagent and DETA-metal complexes are found in process water or tailings streams. In a preferred embodiment, the process water or slurry tailings streams of a mineral processing plant containing DETA, DETA-metal complexes and residual heavy metals are contacted with natural zeolite. This can be carried out by adding the natural zeolite to the process streams (slurries) while mixing with a mechanical mixer to efficiently adsorb DETA, DETA-metal complexes and heavy metals from the process streams (slurries) on the zeolite. The loaded zeolite is then discarded with the flotation tailings.

Abstract translation: 本发明涉及一种使用来自矿物加工厂的工艺用水或尾矿流的沸石去除有机化学品和有机金属络合物（有机重金属络合物）的方法，其中使用二亚乙基三胺（DETA）或三亚乙基四胺（TETA）作为浮选试剂并且 DETA-金属络合物存在于工艺用水或尾矿流中。 在一个优选实施方案中，含有DETA，DETA-金属络合物和残余重金属的矿物加工设备的工艺用水或泥浆尾矿流与天然沸石接触。 这可以通过将天然沸石加入到工艺流（浆料）中同时与机械混合器混合以有效地吸附来自沸石上的工艺流（浆料）的DETA，DETA-金属络合物和重金属来实施。 然后用浮选尾矿废弃负载的沸石。

公开(公告)号：WO2007118431A1

公开(公告)日：2007-10-25

申请号：PCT/CN2007001246

申请日：2007-04-16

Applicant: INST BASIC MED SCIENCES PLA ,  HAINAN GT UNIPUL PHARMACEUTICA ,  YANG GUANG ,  SHAO NINGSHENG ,  GAO YAPING ,  LIU YU ,  DONG JIE ,  LI SHAOHUA ,  LIU CHUAN ,  SHEN BEIFEN ,  FAN MING

Inventor： YANG GUANG ,  SHAO NINGSHENG ,  GAO YAPING ,  LIU YU ,  DONG JIE ,  LI SHAOHUA ,  LIU CHUAN ,  SHEN BEIFEN ,  FAN MING

IPC: A61K38/16 ,  A61K39/085 ,  A61P31/04

CPC classification number: A61K38/164

Abstract: Use of TRAP protein as active ingredient for manufacturing a medicament for the treatment of Staphylococcus aureus infection is provided.

Abstract translation: 提供使用TRAP蛋白作为活性成分制备用于治疗金黄色葡萄球菌感染的药物。

公开(公告)号：WO2005007683A8

公开(公告)日：2006-06-15

申请号：PCT/CN0300827

申请日：2003-09-27

Applicant: LITARY MEDICAL SCIENCES INST O ,  HAINAN GT UNIPUT PHARMACEUTICA ,  SHAO NINGSHENG ,  YANG GUANG ,  LIU CHUAN ,  GAO YAPING ,  DONG JIE ,  DING HONGMEI ,  SHEN BEIFEN

Inventor： SHAO NINGSHENG ,  YANG GUANG ,  LIU CHUAN ,  GAO YAPING ,  DONG JIE ,  DING HONGMEI ,  SHEN BEIFEN

IPC: A61K38/16 ,  A61K39/085 ,  A61P31/04 ,  C07K7/08 ,  C07K14/31 ,  C07K14/315

CPC classification number: C07K14/315

Abstract: This invention relates to two antigen epitopes of regulatory protein TRAP of virulence factor in staphylococcus aureus and their mimotopes. The sequence of the antigen epitope is NPTHQLFQFSASDT or SYFERYLYPIKE. The sequence of the mimotope is XPXHHQHXTGFT or SWFDXXLYPXXX, in which X is any one of 21 kinds of natural L type amino acids D type isomer. The antigen epitopes and their mimotope in this invention can be used to prepare a vaccine or medicine to resist staphylococcus aureus infection.

Abstract translation: 本发明涉及金黄色葡萄球菌及其模拟表位的毒力因子调节蛋白TRAP的两个抗原表位。 抗原表位的序列是NPTHQLFQFSASDT或SYFERYLYPIKE。 模拟表达的序列是XPXHHQHXTGFT或SWFDXXLYPXXX，其中X是21种天然L型氨基酸D型异构体中的任一种。 本发明中的抗原表位及其模拟表位可用于制备抵抗金黄色葡萄球菌感染的疫苗或药物。