公开(公告)号：WO2016187319A1

公开(公告)日：2016-11-24

申请号：PCT/US2016/033104

申请日：2016-05-18

Applicant: VARIAN MEDICAL SYSTEMS, INC. ,  VARIAN MEDICAL SYSTEMS

Inventor： BACH, Markus ,  HUTH, Isabel ,  HEESE, Juergen ,  PISKULICH, Franko ,  DONG, Lei

IPC: A61N5/10

CPC classification number: A61N5/1081 ,  A61N5/1037 ,  A61N5/1044 ,  A61N5/1049 ,  A61N5/1067 ,  A61N5/1068 ,  A61N2005/1087

Abstract: To overcome the difficulties inherent in conventional proton therapy systems, new techniques are described herein for synchronizing the application of proton radiation with the periodic movement of a target area. In an embodiment, a method is provided that combines multiple rescans of a spot scanning proton beam while monitoring the periodic motion of the target area, and aligning the applications of the proton beam with parameters of the periodic motion. For example, the direction(s) and frequency of the periodic motion may be monitored, and the timing, dose rate, and/or scanning direction and spot sequence of the beam can be adjusted to align with phases in the periodic motion.

Abstract translation: 为了克服常规质子治疗系统中固有的困难，本文描述了用于使质子辐射的应用与目标区域的周期性运动同步的新技术。 在一个实施例中，提供了一种组合点扫描质子束的多个重新扫描的方法，同时监视目标区域的周期性运动，并且将质子束的应用与周期性运动的参数对准。 例如，可以监视周期性运动的方向和频率，并且可以调整光束的定时，剂量率和/或扫描方向和点序列以与周期运动中的相位对准。