公开(公告)号：WO2013173524A2

公开(公告)日：2013-11-21

申请号：PCT/US2013/041252

申请日：2013-05-15

Applicant: WELLSTAT DIAGNOSTICS, LLC

Inventor： COOK, Richard, Alan ,  CHO, Sang ,  DAVIS, Charles, Quentin ,  DORSEY, Kevin, E. ,  HARLEY, Jason, Charles ,  LELAND, Jonathan ,  MATIKYAN, Rober, Krikor ,  OTTEN, Sjef ,  PETERMAN, Jeffrey, Howard ,  THOMAS, Brian, B.

IPC: G01N21/66 ,  F04B49/06 ,  H05B1/02 ,  F04B49/10

CPC classification number: B01L3/527 ,  B01L2200/10 ,  B01L2200/16 ,  B01L2300/042 ,  B01L2300/0861 ,  B01L2300/105 ,  B65B1/04 ,  B65B3/04 ,  B65B5/04 ,  B65B55/00 ,  F04B49/065 ,  F04B49/106 ,  G01N21/66 ,  G01N27/3273 ,  G01N33/50 ,  G01N33/536 ,  G01N33/543 ,  G01N33/58 ,  G01N33/582 ,  G01N35/1079 ,  H05B1/025 ,  Y10T436/25 ,  Y10T436/2575

Abstract: In embodiments disclosed herein, a diagnostic system is provided having a cartridge comprising at least one needle; at least one reservoir; at least one fluidic seal; and at least one fluidic channel of a fluidic pathway, wherein the cartridge is configured to store at least one reagent and at least one waste material on the cartridge. The diagnostic system is provided also having a diagnostic instrument comprising the fluidic pathway; an electrochemiluminescence (ECL) detection system; and a pump, wherein the fluidic pathway begins and ends in the cartridge and has a substantially single direction of flow in a pathway fluidically connecting the diagnostic instrument and the cartridge.

Abstract translation: 在本文公开的实施例中，提供了具有包括至少一个针的药筒的诊断系统; 至少一个水库; 至少一个流体密封; 以及至少一个流体通道的流体通道，其中所述筒被构造成在所述筒上存储至少一种试剂和至少一种废料。 该诊断系统还具有包括流体通路的诊断仪器; 电化学发光（ECL）检测系统; 和泵，其中流体通道在药筒中开始和结束，并且在流体连接诊断​​仪器和药筒的通路中具有基本上单一的流动方向。

公开(公告)号：WO2013173525A1

公开(公告)日：2013-11-21

申请号：PCT/US2013/041255

申请日：2013-05-15

Applicant: WELLSTAT DIAGNOSTICS, LLC

Inventor： COOK, Richard Alan ,  CHO, Sang ,  DAVIS, Charles Quentin ,  DORSEY, Kevin E. ,  HARLEY, Jason Charles ,  LELAND, Jonathan ,  MATIKYAN, Rober Krikor ,  OTTEN, Sjef ,  PETERMAN, Jeffrey Howard ,  THOMAS, Brian B.

IPC: G01N27/327 ,  C12M1/00 ,  G01N33/533 ,  C12Q1/00 ,  G01N21/76 ,  G01N33/566 ,  G01N33/58 ,  G01N33/543 ,  G01N27/30 ,  G01N21/66 ,  G01N27/416 ,  G01N33/536 ,  G01N21/00 ,  C12M1/34 ,  G01N33/53

CPC classification number: B01L3/527 ,  B01L2200/10 ,  B01L2200/16 ,  B01L2300/042 ,  B01L2300/0861 ,  B01L2300/105 ,  B65B1/04 ,  B65B3/04 ,  B65B5/04 ,  B65B55/00 ,  F04B49/065 ,  F04B49/106 ,  G01N21/66 ,  G01N27/3273 ,  G01N33/50 ,  G01N33/536 ,  G01N33/543 ,  G01N33/58 ,  G01N33/582 ,  G01N35/1079 ,  H05B1/025 ,  Y10T436/25 ,  Y10T436/2575

Abstract: A diagnostic system is provided herein that includes an instrument comprising an electrochemiluminescence (ECL) detector, and a cartridge configured to fit within a portion of the instrument, wherein the cartridge includes at least one reagent including an ECL label and a blood collection holder. Also provided herein is a system that includes a diagnostic instrument, which includes a pump, an ECL detector, an incubator, a magnet, and an output device, and a cartridge configured to fit within a portion of the diagnostic instrument, a sample holder configured to fit within the cartridge, and a closed fluidic loop between the diagnostic instrument and the cartridge when the cartridge is fit within a portion of the diagnostic instrument, wherein the cartridge is configured to accept a sample from the sample holder and place the sample in fluidic communication with the diagnostic instrument via the closed fluidic loop.

Abstract translation: 本文提供了一种诊断系统，其包括包括电化学发光（ECL）检测器的仪器和被配置为装配在仪器的一部分内的盒，其中所述盒包括至少一种包括ECL标签和采血支架的试剂。 本文还提供了一种系统，其包括诊断仪器，该诊断仪器包括泵，ECL检测器，培养箱，磁体和输出装置，以及被配置为装配在诊断仪器的一部分内的药筒，配置 以及当所述盒安装在所述诊断仪器的一部分内时，在所述诊断仪器和所述药筒之间封闭的流体回路，其中所述药筒被配置为接受来自所述样品保持器的样品并将所述样品置于流体状态 通过封闭的流体回路与诊断仪器进行通讯。