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公开(公告)号：WO2023091552A1
公开(公告)日：2023-05-25
申请号：PCT/US2022/050216
申请日：2022-11-17
IPC分类号： A61M60/13 , A61M60/237 , A61M60/857
摘要： A percutaneous circulatory support device includes a housing, a cannula coupled to the housing, the cannula having a first portion and a second portion, and wherein the cannula includes at least one slot disposed along at least the first portion of the cannula, the at least one slot configured such that the first portion of the cannula is defined by a first stiffness and a second portion of the cannula is defined by a second stiffness, the first stiffness being different than the second stiffness.
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公开(公告)号：WO2023091463A1
公开(公告)日：2023-05-25
申请号：PCT/US2022/050068
申请日：2022-11-16
发明人： GIESE, Troy , KOUDELA, Christopher , EGGERT, Joel
摘要： An introducer assembly is adapted for deploying a medical device. The introducer assembly includes an introducer body that is adapted to accommodate a volume of blood therein. An antechamber is coupled with the introducer body. A first hemostasis valve is disposed proximal of the antechamber and fluidly couples the introducer body with the antechamber. A second hemostasis valve is disposed distal of the antechamber and is adapted to allow the medical device to pass therethrough.
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公开(公告)号：WO2023086863A1
公开(公告)日：2023-05-19
申请号：PCT/US2022/079602
申请日：2022-11-10
摘要： Methods of treating a substrate, e.g., forming a coating on the substrate, are described. The method may include applying a solution comprising a multifunctional molecule or a multifunctional-polymer molecule to at least a portion of a surface of the substrate. The surface may comprise a metal or metal alloy and the multifunctional molecule or a multifunctional-polymer molecule may bond to the surface via at least one sulfur group of a plurality of sulfur groups of the multifunctional molecule. The method may include combining the multifunctional molecule with a polymer molecule to form the multifunctional polymer molecule before or after applying the solution. The polymer molecule may bond to an internal carbon group or a terminal sulfur group of the multifunctional molecule.
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公开(公告)号：WO2023086808A1
公开(公告)日：2023-05-19
申请号：PCT/US2022/079524
申请日：2022-11-09
摘要： A medical device including a handle and a flexible member controlled by the handle, the handle including one or more knobs, each of the one or more knobs having a plurality of protrusions spaced circumferentially from one another, wherein the medical device comprises one or more grip-enhancing features configured to be removably coupled to the one or more knobs.
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公开(公告)号：WO2023086285A1
公开(公告)日：2023-05-19
申请号：PCT/US2022/049080
申请日：2022-11-07
发明人： INOUYE, Joshua Mark
摘要： An occlusive implant may include an expandable framework configured to shift between a collapsed configuration and an expanded configuration. The expandable framework includes a plurality of anchor members extending radially outward from the expandable framework in the expanded configuration, each anchor member including at least one base portion fixedly secured to the expandable framework and a plurality of anchor tips extending from each base portion. Each base portion extends longitudinally along the expandable framework. A method of making the occlusive implant may include forming the expandable framework, forming the plurality of anchor members, and fixedly attaching each base portion to the expandable framework such that each anchor member extends radially outward from the expandable framework in the expanded configuration and each base portion extends longitudinally along the expandable framework.
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公开(公告)号：WO2023069674A1
公开(公告)日：2023-04-27
申请号：PCT/US2022/047369
申请日：2022-10-21
发明人： CLEVELAND, Benjamin , MOREY, Subodh , BAVISKAR, Nitesh Ghananil , SHAIKH, Junaid Mohammed , GRAFFAM, Richard Earl , HERNANDEZ, Joseph , WATSON, Christopher , KOLSTE, Kolbein , BHOWMICK, Nabarun , SUKHATME, Mihir , GOLE, Nachiket , SINGH, Rajivkumar
摘要： The system can include a multi-lumen chamber can removably connected to and in fluid communication with a proximal end of a mixing lumen and include a first lumen aligned with a second lumen. The first lumen can be configured to include a first constituent in a first cavity. A first plunger can be internally positioned within the first lumen to control flow of the first constituent from the first cavity into the mixing lumen. The first cavity can terminate in a first port in fluid communication with the proximal end of the mixing lumen. The second lumen can be configured to include a second constituent. A second plunger can be internally positioned within the second lumen. The second lumen can terminate in a second port adjacent the first port and in fluid communication with the proximal end of the mixing lumen.
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公开(公告)号：WO2023069672A1
公开(公告)日：2023-04-27
申请号：PCT/US2022/047362
申请日：2022-10-21
发明人： CLEVELAND, Benjamin , MOREY, Subodh , BAVISKAR, Nitesh Ghananil , SHAIKH, Junaid Mohammed , GRAFFAM, Richard Earl , HERNANDEZ, Joseph , WATSON, Christopher , KOLSTE, Kolbein , BHOWMICK, Nabarun , SUKHATME, Mihir , GOLE, Nachiket , SINGH, Rajivkumar , DESANTIS, Nicholas , KIM, Eric , AMEND, Mei Lee
摘要： A system includes a connector with a central lumen. A multi-lumen chamber is removably connected to and in fluid communication with a proximal end of the central lumen. The multi-lumen chamber includes a first lumen aligned and adjacent a second lumen. The first lumen includes a first fluid in a proximal portion of the first lumen and a hydrophilic polymer in a distal portion of the first lumen, a first plunger rod within the first lumen to control flow of the first fluid into the distal portion to mix with the hydrophilic polymer in a first state to form a first mixture, and a first port. The second lumen includes a second fluid, a second plunger rod within the second lumen to distally move the second fluid and the first mixture in a second state, and a second port.
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公开(公告)号：WO2023069188A1
公开(公告)日：2023-04-27
申请号：PCT/US2022/041263
申请日：2022-08-23
IPC分类号： A61B17/3207 , A61B34/00
摘要： An atherectomy system includes a user interface that an operator engages with in order to indicate requested movement of a drive assembly. One or more sensors are adapted to ascertain one or more conditions of the drive assembly and to output one or more condition signals to a controller that is operably coupled with the operator assembly and the drive assembly. The controller is adapted to receive the request signal from the operator assembly and the one or more condition signals, to determine a command signal in response to the received request signal and the received one or more condition signals, and provide the command signal to the drive assembly. The drive assembly is adapted to move relative to the advancer assembly in accordance with the command signal.
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公开(公告)号：WO2023064262A1
公开(公告)日：2023-04-20
申请号：PCT/US2022/046260
申请日：2022-10-11
摘要： A device for radially compressing a stent may include a housing including a central opening and a first iris positioned adjacent the housing. The first iris includes a first circumferential ring and a first plurality of arms extending radially inward from the first circumferential ring to define a first central opening. The device may include a second iris axially offset from the first iris and including a second circumferential ring and a second plurality of arms extending radially inward from the second circumferential ring to define a second central opening. Rotation of the circumferential ring(s) relative to the housing changes a size of their respective central opening(s). The plurality of arms may shift between a first configuration and a second configuration via rotation of the circumferential ring(s) relative to the housing.
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公开(公告)号：WO2023028414A1
公开(公告)日：2023-03-02
申请号：PCT/US2022/074505
申请日：2022-08-04
摘要： A laser system includes a first laser configured to generate a laser light, the first laser light including a first wavelength, a second laser configured to generate a second laser light, the second laser light including a second wavelength different from the first wavelength, and a laser fiber operatively coupled to each of the first laser and the second laser to emit at least one of the first laser light or the second laser light at a target site.
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