METHOD OF PROTECTING ACTIVE INGREDIENT FROM DEGRADATION DURING PELLETING
    2.
    发明申请
    METHOD OF PROTECTING ACTIVE INGREDIENT FROM DEGRADATION DURING PELLETING 审中-公开
    保护活性成分在剥离过程中降解的方法

    公开(公告)号:WO2014022761A2

    公开(公告)日:2014-02-06

    申请号:PCT/US2013053395

    申请日:2013-08-02

    IPC分类号: A23K1/00 A61K9/50

    摘要: A system for the protection against degradation during pelleting of one or more physiologically or pharmacologically active substances, comprising compositions in the form of micro particles or granules, particularly for use in the zootechnical and/or veterinary field. The micro particles include a core which contains one or more substances having a pharmacological action, food supplements or diagnostic media, said one or more substances being characterized by the presence, within their chemical structure, of a basic functional group, specifically including an amine functional group. The core comprises also one or more carboxylic acids and/or their salts and eventually one or more excipients. Said core is coated by an outer layer of fats or waxes, and preferably by a mixture of glyceride of fatty acids.

    摘要翻译: 一种用于防止在一种或多种生理或药理学活性物质造粒期间降解的系统,其包含微粒或颗粒形式的组合物,特别是用于畜牧和/或兽医领域。 微粒包括含有一种或多种具有药理作用的物质的核心,食物补充剂或诊断介质,所述一种或多种物质的特征在于在其化学结构内存在碱性官能团,特别包括胺官能团 组。 核心还包括一种或多种羧酸和/或其盐,最后还包括一种或多种赋形剂。 所述芯由脂肪或蜡的外层,优选由脂肪酸的甘油酯的混合物包衣。