公开(公告)号：WO2018067359A1

公开(公告)日：2018-04-12

申请号：PCT/US2017/053756

申请日：2017-09-27

Applicant: VERILY LIFE SCIENCES LLC

Inventor： OTTS, Daniel, B.

IPC: A61F2/16 ,  G02B26/00 ,  G02C7/08

CPC classification number: A61F2/1635 ,  A61F2/1627 ,  A61F2/1648 ,  A61F2/1675 ,  A61F2002/16905 ,  A61F2210/0076 ,  A61F2250/0001 ,  A61F2250/0002 ,  A61F2250/0091 ,  A61F2250/0092 ,  A61F2250/0096 ,  G02B26/005 ,  G02C7/085

Abstract: An open, seal-less intraocular lens is disclosed herein. An example intraocular lens may include an annular substrate (102) including an oil electrode (104) disposed in or on an inner sidewall of the annular substrate to electrostatically manipulate a volume of electrowetting oil, an optical window (106) coupled to the substrate, where a side of the optical window adjacent to the inner sidewall and the inner sidewall of the annular substrate define a region for constraining the volume of electrowetting oil, and a saline electrode (116) coupled to the annular substrate, the saline electrode positionable within an aqueous humor of an eye upon implantation.

Abstract translation: 本文公开了一种开放的无密封眼内晶状体。 一个示例的人工晶状体可以包括环形衬底（102），光学窗口（106）包括设置在环形衬底的内侧壁中或上的油电极（104）以静电操纵一定体积的电润湿油，光学窗口（106） 其中光学窗口的与环形衬底的内侧壁和内侧壁相邻的一侧限定用于约束电润湿油的体积的区域，以及耦合到环形衬底的盐水电极（116），盐水电极可定位在 植入后眼睛的房水。

公开(公告)号：WO2017083315A1

公开(公告)日：2017-05-18

申请号：PCT/US2016/061012

申请日：2016-11-08

Applicant: HOYA CORPORATION ,  ZHANG, Xiao, Xiao

Inventor： ZHANG, Xiao, Xiao

IPC: A61F2/16

CPC classification number: A61F2/1648 ,  A61F2/1602 ,  A61F2002/1696 ,  A61F2250/0053

Abstract: An optical device (2300) including a partial or incomplete optic (2320) configured operatively as an add-on (e.g., supplemental lens/optic) for an (existing) optical element or system, the partial or incomplete optic having an active area configured in relation to the optical element or system such that the partial or incomplete optic controls or changes foci of light incident upon or provided to the active area, but does not control or change foci of light bypassing optically relevant portions of the partial or incomplete optic, and associated methods for enhancing vision.

Abstract translation: 包括可操作地配置为用于（现有）光学元件或系统的附加（例如，补充透镜/光学器件）的部分或不完全光学器件（2320）的光学器件（2300），部分 或不完整的光学器件，其具有相对于光学元件或系统配置的有源区域，使得部分或不完全光学器件控制或改变入射到或提供给有源区域的光的焦点，但不控制或改变光的焦点，从而绕过光学相关 部分或不完整的光学部件，以及增强视力的相关方法。

公开(公告)号：WO2017015328A1

公开(公告)日：2017-01-26

申请号：PCT/US2016/043068

申请日：2016-07-20

Applicant: ELWHA LLC

Inventor： CHEATHAM, Jesse R., III ,  HYDE, Roderick A. ,  MARSHALL, John ,  TEGREENE, Clarence T. ,  WOOD, Lowell L., Jr. ,  ZALDIVAR, Roberto ,  ZALDIVAR, Roger

IPC: A61F2/16 ,  A61F2/48

CPC classification number: A61F2/1627 ,  A61B3/103 ,  A61F2/16 ,  A61F2/1648 ,  A61F2/1659 ,  A61F2250/0002

Abstract: Embodiments disclosed herein are directed to intraocular lens systems includes at least one intraocular lens device and methods of using the same. The at least one intraocular lens device includes one or more photodetectors and an intraocular lens exhibiting a modifiable focal length. The one or more photodetectors are configured to detect light that is used to determine a presence of the object or the apparent object distance. The focal length of the intraocular lens can be modified depending on the determined presence of the object or the apparent object distance.

Abstract translation: 本文公开的实施例涉及眼内透镜系统，其包括至少一个眼内透镜装置及其使用方法。 所述至少一个眼内透镜装置包括一个或多个光电检测器和呈现可修改焦距的眼内透镜。 一个或多个光电检测器被配置为检测用于确定物体的存在或表观物体距离的光。 可以根据确定的物体的存在或表观物体距离来修改眼内透镜的焦距。

公开(公告)号：WO2016093896A1

公开(公告)日：2016-06-16

申请号：PCT/US2015/044015

申请日：2015-08-06

Applicant: NOVARTIS AG ,  DOLLA, William J.S. ,  GUPTA, Parag ,  LIANG, Liezhi

Inventor： DOLLA, William J.S. ,  GUPTA, Parag ,  LIANG, Liezhi

IPC: A61F2/16

CPC classification number: A61F2/1635 ,  A61F2/1648 ,  A61F2002/1682 ,  A61F2002/16901

Abstract: The present disclosure concerns a curvature-changing, accommodative intraocular lens (IOL) that may be implanted in the capsular bag of a patients eye and is configured to harness the energy of the movement of the capsular bag upon contraction and relaxation of the ciliary muscles. In certain embodiments, the IOL includes a fluid optic body defining a cavity for containing an optical fluid, the cavity at least partially defined by a first optical membrane configured to extend across an optical axis of the patients eye. The IOL further includes a plurality of lever arms extending from the optic body and configured to be in contact with the capsular bag such that axial compression of the capsular bag causes each of the plurality of lever arms to rotate about a corresponding pivot so as to modify a curvature of the first optical membrane.

Abstract translation: 本公开涉及可以植入患者眼睛的囊袋中的曲率改变的调节性眼内透镜（IOL），并且被构造成在睫状肌收缩和松弛时利用囊袋的移动能量。 在某些实施例中，IOL包括限定用于容纳光学流体的空腔的流体光学主体，所述空腔至少部分地由配置成延伸穿过患者眼睛的光轴的第一光学膜限定。 IOL还包括多个杠杆臂，其从光学主体延伸并被构造成与囊袋接触，使得囊袋的轴向压缩使得多个杠杆臂中的每一个绕相应的枢轴旋转，以便修改 第一光学膜的曲率。

公开(公告)号：WO2016062503A3

公开(公告)日：2016-06-16

申请号：PCT/EP2015072457

申请日：2015-09-29

Applicant: IMPLANDATA OPHTHALMIC PRODUCTS GMBH

Inventor： OSTERMEIER MAX ,  MEYER STEFAN

IPC: A61F2/16 ,  A61B3/16

CPC classification number: A61F2/1675 ,  A61B3/16 ,  A61F2/1648 ,  A61F2/1694 ,  A61F2220/0025 ,  A61F2220/0033 ,  A61F2220/0083

Abstract: The invention relates to a combined eye implant (1) for implantation into a capsular bag (6) of the human or animal eye, in particular in the course of a cataract operation, the implant comprising: a substantially annular sensor implant (11), which surrounds a central cut-out section (3) and which has a pressure sensor (7) for measuring the intraocular pressure and microelectronics (8) for converting signals of the pressure sensor (7) into digital data and for transmitting this data to an external read-device via an antenna (9); and a lens implant (12), which, when implanted, at least partially covers the central cut-out section (3) of the sensor implant (11). In order to avoid mutual functional interference between the lens implant (12) and the sensor implant (11), according to the invention, the eye implant is improved by the provision of one or more retaining elements (13, 14) which secure the relative position of the sensor implant (11) to the lens implant (12) in an axial direction (2), allowing at least a minor relative displacement of the sensor implant (11) in relation to the lens implant (12) in a radial direction running orthogonally to the axial direction (2).

Abstract translation: 的组合的眼植入物（1）用于植入在囊袋中（6）的人或动物的眼，尤其是在白内障手术中，具有基本上环形的，中央凹槽（3）包围的，传感器植入物（11）包括压力传感器（7 ），用于测量所述眼压，微电子器件（8），用于压力传感器的信号转换（7）转换成数字数据，并经由天线（9），以将该数据传送给外部读取器，和一个透镜植入物（12），其是在 植入状态下的中央凹部（3）的传感器植入物（11）至少部分地覆盖的，根据本发明，以避免透镜植入物（12）和传感器植入物（11）的相互损伤是由于这样的事实改善的一个或多个保持元件（13，14）被提供，其 沿轴向（2）固定传感器植入物（11）相对于晶状体植入物（12）的相对位置， 允许传感器植入物（11）在轴向方向（2）的正交径向上的透镜植入物（12）相对的至少轻微的相对位移。

公开(公告)号：WO2016076714A1

公开(公告)日：2016-05-19

申请号：PCT/NL2015/050785

申请日：2015-11-10

Applicant: AKKOLENS INTERNATIONAL B.V.

Inventor： SIMONOV, Aleksey Nikolaevich ,  ROMBACH, Michiel Christiaan

IPC: A61F2/16 ,  G02C7/02

CPC classification number: A61F2/1648 ,  A61F2/1637 ,  A61F2230/0084 ,  G02C7/02

Abstract: The present invention provides an ophthalmic lens adapted to provide extended depth of field and adapted to be positioned anywhere between the object and the retina of the eye, the lens comprising at least one optical element (1) having a first optical surface (2) adapted to be positioned on the anterior side of the optical element and a second optical surface (3) adapted to be positioned on the posterior side of the optical element, wherein said optical surfaces include at least one optical shape according to a polynomial of the fourth degree, wherein the arrangement is adapted to provide an optical function for a polynomial of the third degree providing said extension of depth of field.

Abstract translation: 本发明提供了一种眼镜片，其适于提供延长的景深并适于定位在眼睛的物体和视网膜之间的任何位置，透镜包括至少一个光学元件（1），该光学元件具有适于 位于光学元件的前侧上，第二光学表面（3）适于定位在光学元件的后侧，其中所述光学表面包括根据第四度的多项式的至少一种光学形状 ，其中所述装置适于为提供所述景深延伸的所述第三度的多项式提供光学功能。

公开(公告)号：WO2016058051A1

公开(公告)日：2016-04-21

申请号：PCT/AU2015/050634

申请日：2015-10-15

Applicant: CORONEO, Minas Theodore

Inventor： CORONEO, Minas Theodore

IPC: A61F2/16

CPC classification number: A61F2/1656 ,  A61B3/12 ,  A61F2/1451 ,  A61F2/1648 ,  A61F2002/16902 ,  A61F2002/1696 ,  G02B1/041 ,  G02C7/04 ,  G02C7/14

Abstract: An intraocular lens, and use thereof, the lens configured to reduce or eliminate oblique incident light photic disturbances in the eye, said lens comprising anterior and posterior surfaces defining a central lens optic extending from said anterior to said posterior surfaces and a peripheral portion outside of the central lens optic, wherein the peripheral portion is a prismatic lens which redirects oblique incident light on the peripheral portion forward of the nasal retina in the eye and onto the ciliary body/pars plana region.

Abstract translation: 眼内透镜及其用途，所述透镜被配置为减少或消除眼睛中的倾斜入射光线干扰，所述透镜包括前表面和后表面，所述透镜包括从所述前部延伸到所述后表面的中心透镜光学元件， 中心透镜光学元件，其中周边部分是棱镜透镜，其将倾斜的入射光重定向在眼睛中的鼻视网膜前方的周边部分上并且到睫状体/平面平面区域。

公开(公告)号：WO2016049005A1

公开(公告)日：2016-03-31

申请号：PCT/US2015/051415

申请日：2015-09-22

Applicant: CADY, Kevin J.

Inventor： CADY, Kevin J.

IPC: A61F2/16

CPC classification number: A61F2/1602 ,  A61F2/1648 ,  A61F2/1694 ,  A61F9/0017 ,  A61F2002/1681 ,  A61F2002/16902 ,  A61F2220/0016

Abstract: Various intraocular pseudophakic contact lenses (100, 400, 800, 900, 1600, 1700, 1800, 1900, 2000) are disclosed. For example, an intraocular pseudophakic contact lens can include a first optical lens (102, 402, 802, 902, 1602, 1702, 1802, 1902, 2002, 2100, 2102, 2200, 2250, 2300, 2400) and multiple anchors (106a-106b, 406a-406b, 1500). The first optical lens is configured to at least partially correct a residual refractive error in an eye (1300). The anchors are configured to be inserted through an anterior surface of an intraocular lens (1000) into lens material (1006) forming a second optical lens (1002) of the intraocular lens in order to secure the intraocular pseudophakic contact lens to the intraocular lens. The anchors can be configured to couple the intraocular pseudophakic contact lens to different types of intraocular lenses, including intraocular lenses not specifically designed to be coupled to or receive the intraocular pseudophakic contact lens. The intraocular pseudophakic contact lens could also include at least one drug-eluting device (1706, 1806, 1906) located on the first optical lens and configured to deliver at least one medication.

Abstract translation: 公开了各种眼内假晶状隐形眼镜（100,400,800,900,1600,1700,1800,1900,2000）。 例如，眼内假晶状隐形眼镜可以包括第一光学透镜（102,402,802,902,1602,1702,1802,1902,2200,2100,210,2200,22250,2300,200400）和多个锚定部（106a） -106b，406a-406b，1500）。 第一光学透镜被配置为至少部分地校正眼睛中的残余折射误差（1300）。 锚固件被配置为通过眼内透镜（1000）的前表面插入形成眼内透镜的第二光学透镜（1002）的透镜材料（1006）中，以将眼内假晶状隐形眼镜固定在眼内透镜上。 锚固件可被配置成将眼内假晶状隐形眼镜连接到不同类型的人工晶状体，包括未被专门设计为偶联或接收眼内假晶状隐形眼镜的眼内透镜。 眼内假晶状隐形眼镜还可以包括位于第一光学透镜上的至少一个药物洗脱装置（1706,1806,1906），并且构造成输送至少一种药物。

公开(公告)号：WO2016038470A2

公开(公告)日：2016-03-17

申请号：PCT/IB2015/002398

申请日：2015-03-10

Applicant: AMO GRONINGEN B.V.

Inventor： ROSEN, Robert ,  WEEBER, Hendrik, A. ,  VIDAL, Carmen, Canovas ,  VAN DER MOOREN, Marrie ,  SELLITRI, Dora ,  PIERS, Patricia, Ann

IPC: A61F2/16

CPC classification number: A61F2/1637 ,  A61B3/0025 ,  A61B3/028 ,  A61B3/1005 ,  A61B3/103 ,  A61B3/107 ,  A61B3/14 ,  A61F2/1602 ,  A61F2/1605 ,  A61F2/1613 ,  A61F2/1618 ,  A61F2/164 ,  A61F2/1645 ,  A61F2/1648 ,  A61F2/1654 ,  A61F2/1656 ,  A61F2/1659 ,  A61F2002/1681 ,  A61F2240/002

Abstract: Systems and methods are provided for improving overall vision in patients suffering from a loss of vision in a portion of the retina (e.g., loss of central vision) by providing a dual optic intraocular lens which redirects and/or focuses light incident on the eye at oblique angles onto a peripheral retinal location. The intraocular lens can include a redirection element (e.g., a prism, a diffractive element, or an optical component with a decentered GRIN profile) configured to direct incident light along a deflected optical axis and to focus an image at a location on the peripheral retina. Optical properties of the intraocular lens can be configured to improve or reduce peripheral errors at the location on the peripheral retina. One or more surfaces of the intraocular lens can be a toric surface, a higher order aspheric surface, an aspheric Zernike surface or a Biconic Zernike surface to reduce optical errors in an image produced at a peripheral retinal location by light incident at oblique angles.

Abstract translation: 提供了系统和方法，用于通过提供双眼光学眼镜片来改善患有视网膜部分视力丧失（例如，中心视觉丧失）的患者的总体视力，所述双光学眼内镜片重定向和/ 或将以斜角入射到眼睛上的光聚焦到周边视网膜位置上。 眼内透镜可以包括被配置为沿着偏转的光轴引导入射光并将图像聚焦在周边视网膜上的位置的重定向元件（例如，棱镜，衍射元件或具有偏心GRIN轮廓的光学部件） 。 可配置人工晶状体的光学特性以改善或减少周边视网膜上的位置处的周边误差。 人工晶状体的一个或多个表面可以是复曲面，高阶非球面，非球面泽尼克面或双锥形泽尼克面，以减少由倾斜入射的光在周边视网膜位置处产生的图像中的光学误差。 / p>

公开(公告)号：WO2015177651A1

公开(公告)日：2015-11-26

申请号：PCT/IB2015/001588

申请日：2015-04-21

Applicant: AMO GRONINGEN B.V.

Inventor： ROSEN, Robert ,  WEEBER, Hendrik, A. ,  VIDAL, Carmen, Canovas ,  VAN DER MOOREN, Marrie, H. ,  STATE, Mihai ,  PIERS, Patricia, Ann ,  HEREDIA, Aixa, Alarcon

IPC: A61F2/16

CPC classification number: A61F2/164 ,  A61F2/1613 ,  A61F2/1618 ,  A61F2/1648

Abstract: The present disclosure relates to devices, systems, and methods for improving or optimizing peripheral vision. In particular, methods are disclosed which include utilizing particular characteristics of the retina in improving or optimizing peripheral vision. Additionally, various IOL designs, as well as IOL implantation locations, are disclosed which improve or optimize peripheral vision.

Abstract translation: 本公开涉及用于改善或优化周边视觉的装置，系统和方法。 具体地，公开了包括利用视网膜的特征来改善或优化周边视觉的方法。 此外，公开了改善或优化周边视觉的各种IOL设计以及IOL植入位置。