公开(公告)号：WO2018130629A1

公开(公告)日：2018-07-19

申请号：PCT/EP2018/050707

申请日：2018-01-12

Applicant: KRUI AB

Inventor： KNUTSSON, Per

IPC: A61M5/31 ,  A61M5/50 ,  A61M5/315

CPC classification number: A61M5/3134 ,  A61M5/5013 ,  A61M5/502 ,  A61M5/5066 ,  A61M2005/3132 ,  A61M2005/31516 ,  A61M2005/5073 ,  A61M2205/273

Abstract: A syringe is provided. The syringe (10) comprises a barrel (11) with a lumen, said barrel (11) being adapted to contain a drug, the barrel (11) having a distal end wall portion (13) and a tubular wall (12) extending proximally from said distal end wall 5 portion (13). The barrel (11) extending along an axis (100), whereby the distal end wall portion (13) has an opening (14) extending into a syringe head (40) adapted to receive a syringe needle, said syringe head (40) having a lumen smaller in transversal cross- section than the barrel lumen. The syringe (10) further comprises a plunger shaft (96) extending along the axis (100), said plunger shaft being displaceable along the axis (100) within said barrel (11) and a plunger (30) attached to a distal end of said plunger shaft (96); the plunger (30) being adapted to be in fluid-tight engagement with the tubular wall (12) of the barrel (11). The plunger (30) further has a protrusion (33) adapted to fit in fluid-tight engagement in the lumen of the syringe head (40). The syringe head (40) comprising at least one axial passage (42) in fluid communication with the barrel (11), said axial passage (42) being located laterally of the protrusion (33) when the protrusion (33) is positioned in the lumen of the syringe head (40).

公开(公告)号：WO2016172396A3

公开(公告)日：2016-12-01

申请号：PCT/US2016028723

申请日：2016-04-21

Applicant: SAAB IHAB

Inventor： SAAB IHAB

IPC: A61M5/31

CPC classification number: A61M5/31596 ,  A61M5/284 ,  A61M5/502 ,  A61M2005/1787 ,  A61M2005/31506 ,  A61M2005/31598

Abstract: It is known that fluids, for example, drugs, may be administered via a syringe. It is further known that in some instances, a second fluid must be administered following the administration of a first fluid in order to flush the first fluid. There are numerous reasons for why such flushing may be required and/or desirable. For example, flushing ensures that a patient has received the entirety of a dose of the first fluid (e.g., a drug), that the first fluid does not mix and/or react with a subsequently administered (third) fluid that may be incompatible with the first fluid, and/or that the infusion lines are clean and/or primed for a subsequent infusion, to cite a few examples. The present invention is a novel syringe design that houses the flushing solution as part of the syringe to streamline the fluid delivery (drug) and the flushing solution subsequently.

Abstract translation: 已知流体，例如药物可以通过注射器施用。 还已知在一些情况下，必须在施用第一流体之后施用第二流体以冲洗第一流体。 为什么可能需要和/或需要这种冲洗有很多原因。 例如，冲洗确保患者已经接收到第一流体（例如药物）的整体剂量，第一流体不与以下给药的（第三）流体混合和/或与下列物质不相容的第三流体反应 第一流体和/或输液管线是干净的和/或引发用于随后的输注，引用了一些例子。 本发明是一种新颖的注射器设计，其将冲洗溶液作为注射器的一部分容纳以便随后流体输送（药物）和冲洗液。

公开(公告)号：WO2016172396A2

公开(公告)日：2016-10-27

申请号：PCT/US2016/028723

申请日：2016-04-21

Applicant: SAAB, Ihab

Inventor： SAAB, Ihab

IPC: A61M5/19

CPC classification number: A61M5/31596 ,  A61M5/284 ,  A61M5/502 ,  A61M2005/1787 ,  A61M2005/31506 ,  A61M2005/31598

Abstract: It is known that fluids, for example, drugs, may be administered via a syringe. It is further known that in some instances, a second fluid must be administered following the administration of a first fluid in order to flush the first fluid. There are numerous reasons for why such flushing may be required and/or desirable. For example, flushing ensures that a patient has received the entirety of a dose of the first fluid (e.g., a drug), that the first fluid does not mix and/or react with a subsequently administered (third) fluid that may be incompatible with the first fluid, and/or that the infusion lines are clean and/or primed for a subsequent infusion, to cite a few examples. The present invention is a novel syringe design that houses the flushing solution as part of the syringe to streamline the fluid delivery (drug) and the flushing solution subsequently.

Abstract translation: 已知可以通过注射器施用流体，例如药物。 进一步已知，在一些情况下，必须在施用第一流体之后施用第二流体以冲洗第一流体。 为什么需要和/或需要这种冲洗有许多原因。 例如，冲洗确保患者已经接收到第一流体（例如药物）的全部剂量，第一流体不会混合和/或与后续施用的（第三）流体可能不相容 第一流体和/或输注管线是干净的和/或准备用于随后的输注，举几个例子。 本发明是一种新颖的注射器设计，其容纳作为注射器的一部分的冲洗溶液以随后使流体输送（药物）和冲洗溶液流线化。

公开(公告)号：WO2015026423A1

公开(公告)日：2015-02-26

申请号：PCT/US2014/041389

申请日：2014-06-06

Applicant: INFUSION MEDICAL, INC.

Inventor： DAVIDIAN, Daniel, K. ,  NEWNAM, Scott, G. ,  NICHOLS, Eli, B. ,  MOSLER, Theodore, J.

IPC: A61J1/20 ,  A61M5/178

CPC classification number: A61J1/2096 ,  A61J1/201 ,  A61J1/2055 ,  A61J1/2075 ,  A61J1/22 ,  A61M5/001 ,  A61M5/1782 ,  A61M5/2425 ,  A61M5/2448 ,  A61M5/3137 ,  A61M5/31586 ,  A61M5/31591 ,  A61M5/31593 ,  A61M5/502 ,  A61M2202/048 ,  A61M2205/75

Abstract: A syringe fill system is described, which is useful for filling syringes for dental anesthetic applications. The system incorporates capability for "push-pull", "pull-push", "push-push", and "pull-pull" modes of operation, for loading syringes with compositions comprising multiple fluid components. A syringe fillable by such syringe fill systems is described, providing haptic and audible feedback to a user, to aid in administering precise amounts of therapeutic compositions. Also disclosed are cassette assemblies for use in such syringe fill systems. Such cassette assemblies may be formed of plastic and elastomeric materials of construction, as disposable or single -use components of the syringe fill system.

Abstract translation: 描述了注射器填充系统，其用于填充用于牙科麻醉应用的注射器。 该系统具有“推拉”，“推拉式”，“推动式”和“拉式”操作模式的功能，用于将包含多种流体组分的组合物装入注射器。 描述了可由这种注射器填充系统填充的注射器，向使用者提供触觉和可听见的反馈，以帮助施用精确量的治疗组合物。 还公开了用于这种注射器填充系统的盒组件。 这种盒式组件可以由塑料和弹性材料构成，作为注射器填充系统的一次性或单独使用的部件。

公开(公告)号：WO2014194918A1

公开(公告)日：2014-12-11

申请号：PCT/DK2014/050161

申请日：2014-06-04

Applicant: MEDIJECT APS

Inventor： HETTING, Mikkel

IPC: A61M5/315

CPC classification number: A61M5/3202 ,  A61M5/31513 ,  A61M5/502 ,  A61M2005/3109

Abstract: The present invention relates to piston for use in an injector comprising a cylinder having a longitudinal axis and an inner wall, which piston has a deformable sealing element with a convex surface, which deformable sealing element when the piston is inserted in the cylinder abuts the inner wall of the cylinder at an abutting interface and seals an annular gap between the piston and the inner wall of the cylinder, the abutting interface and the deformable sealing element having axial dimensions parallel with the longitudinal axis, characterised in that the ratio between the axial dimension of the abutting interface and the axial dimension of the deformable sealing element is in the range between 0.01 and 0.2. In other aspects the invention relates to an injector comprising the piston and to the use in a disposable syringe of the piston. The piston can prevent refilling of a syringe.

Abstract translation: 本发明涉及用于喷射器的活塞，其包括具有纵向轴线和内壁的气缸，该活塞具有可变形的密封元件，该活塞具有凸形表面，当活塞插入气缸中时，该可变形密封元件邻接内部 圆柱体的邻接界面处的壁，并且密封活塞和气缸的内壁之间的环形间隙，邻接界面和可变形密封元件具有与纵向轴线平行的轴向尺寸，其特征在于，轴向尺寸 的可接合界面和可变形密封元件的轴向尺寸在0.01和0.2之间的范围内。 在其它方面，本发明涉及一种包括活塞和用于活塞的一次性注射器中的注射器。 活塞可以防止注射器重新注入。

公开(公告)号：WO2014088993A1

公开(公告)日：2014-06-12

申请号：PCT/US2013/072728

申请日：2013-12-03

Applicant: BECTON, DICKINSON AND COMPANY

Inventor： YEVMENENKO, Yan ,  WONG, Andrew

IPC: A61M5/50

CPC classification number: A61M5/5066 ,  A61M5/502 ,  A61M2005/5073

Abstract: Syringe assemblies having a passive disabling system to prevent reuse are provided. According to one or more embodiments, the syringe assembly comprises a barrel, plunger rod and detachable thumb press wherein the plunger rod further comprises flexible locking petals that lock the plunger rod within the barrel and one or more frangible connection or break point at the proximal end of the plunger rod disposed either inside the thumb press or immediately adjacent to the thumb press to separate the thumb press from the main body of the plunger rod when a user applies sufficient proximal force to the plunger rod after it has been locked within the barrel.

Abstract translation: 提供了具有防止重复使用的被动禁用系统的注射器组件。 根据一个或多个实施例，注射器组件包括筒体，柱塞杆和可拆卸拇指按压器，其中柱塞杆还包括将柱塞杆锁定在筒内的柔性锁定瓣和近端的一个或多个易碎连接或断裂点 的柱塞杆设置在拇指压力机内部或紧邻拇指压力机，以在使用者在柱塞杆锁定在枪管内之后向柱塞杆施加足够的近侧力时将拇指按压器与柱塞杆的主体分开。

公开(公告)号：WO2013140380A2

公开(公告)日：2013-09-26

申请号：PCT/IB2013052303

申请日：2013-03-22

Applicant: WOLFE TORY MEDICAL INC

Inventor： DENTON MARSHALL T ,  CROLL PERRY W ,  CHRISTENSEN MARK A ,  TRAN HUY N

IPC: A61M5/50

CPC classification number: A61M5/5066 ,  A61M5/31501 ,  A61M5/502 ,  A61M2005/5073

Abstract: A syringe structured to permit multiple filling and emptying cycles with a single syringe, but then to automatically disable that syringe to resist syringe reuse subsequent to a final dose-ejecting cycle. The syringe includes a plunger with a distal tip carrying capture structure that protrudes from the dispensing aperture of the syringe at a fluid fully-expelled position. A fluid discharge attachment can be coupled to the syringe to guide dispensing one or more dose of treatment substance. A first locking element, typically carried by the fluid discharge attachment, couples with the capture structure to resist retraction of the fully-depressed plunger, and thereby resists reciprocation of the plunger to prevent reuse of the syringe. Effectively, the discharge aperture of the syringe is pinned between an internally disposed stopper and the external capture structure. A stem of the plunger may optionally be structured to detach, leaving the stopper behind inside the syringe body, to further frustrate reuse of the syringe. Sometimes, a second locking element may be included to also resist unscrewing a fluid discharge device from a syringe.

Abstract translation: 一种注射器，其构造为允许用单个注射器进行多次填充和排空循环，然后自动禁用该注射器以抵抗在最终剂量 - 喷射循环之后的注射器重复使用。 注射器包括具有远端的携带捕获结构的柱塞，所述捕获结构在流体完全排出位置处从注射器的分配孔突出。 流体排放附件可以联接到注射器以引导分配一个或多个剂量的治疗物质。 通常由流体排放附件携带的第一锁定元件与捕获结构耦合以阻止完全凹陷的柱塞的缩回，从而抵抗柱塞的往复运动以防止注射器的再次使用。 有效地，将注射器的排出孔钉在内部设置的塞子和外部捕获结构之间。 柱塞的杆可以可选地被构造成分离，使塞子留在注射器主体内部，以进一步阻止注射器的重新使用。 有时，可以包括第二锁定元件，以抵抗从注射器旋转流体排出装置。

公开(公告)号：WO2012012631A1

公开(公告)日：2012-01-26

申请号：PCT/US2011/044841

申请日：2011-07-21

Applicant: BECTON, DICKINSON AND COMPANY ,  ZIVKOVIC, Ivan ,  BATTLES, Christopher A. ,  GLEASON, James ,  RADZIUNAS, Jeffrey

Inventor： ZIVKOVIC, Ivan ,  BATTLES, Christopher A. ,  GLEASON, James ,  RADZIUNAS, Jeffrey

IPC: A61M5/32 ,  A61M5/50

CPC classification number: A61M5/5066 ,  A61M5/3213 ,  A61M5/3232 ,  A61M5/3276 ,  A61M5/347 ,  A61M5/502 ,  A61M2005/3227

Abstract: Embodiments of a retractable syringe assembly are provided that include a dual syringe barrel configuration. One or more embodiments include reuse prevention features and features that prevent premature activation of the retraction mechanism. Methods for aspirating and expelling liquid from medical devices are also provided.

Abstract translation: 提供了包括双注射器筒构造的可缩回注射器组件的实施例。 一个或多个实施例包括防止缩回机构过早激活的防止重新使用的特征和特征。 还提供了从医疗设备中抽吸和排出液体的方法。

公开(公告)号：WO2010062393A1

公开(公告)日：2010-06-03

申请号：PCT/US2009/006287

申请日：2009-11-25

Applicant: BECTON, DICKINSON AND COMPANY ,  BURNS, Steven ,  COLE, Russell ,  LUM, Chee, Leong ,  MARTINEZ LLANOS, David ,  SOLTZ, Michael ,  ARAZO URRACA, Ramon ,  SALDANA, Luis

Inventor： BURNS, Steven ,  COLE, Russell ,  LUM, Chee, Leong ,  MARTINEZ LLANOS, David ,  SOLTZ, Michael ,  ARAZO URRACA, Ramon ,  SALDANA, Luis

IPC: A61M5/00

CPC classification number: A61M5/502 ,  A61M5/3146 ,  A61M5/3202 ,  A61M5/3213 ,  A61M2005/5026 ,  A61M2005/5033 ,  A61M2205/581 ,  A61M2205/582 ,  Y10T29/49268

Abstract: A single-use auto-disable syringe device of reduced size utilizes a locking element to prevent re-use of the syringe by locking the plunger rod with respect to the barrel upon completion of an injection stroke. The plunger rod includes a plurality of teeth and an intermediate tooth provided on a distal-most tooth to prevent the user from repeatedly drawing in doses too small to activate the safety mechanism and a breakable section configured to break upon the application of excessive force. The breakable section is preferably provided at a distal end of the plunger rod so that a proximal end of the locking element engages the syringe barrel and plunger rod at a position more proximal than the breakable section. In this way, the locking element resists some of the force that would otherwise be applied to the breakable section if the plunger rod were twisted.

Abstract translation: 减小尺寸的一次性自动禁用注射器装置利用锁定元件来防止在注射冲程完成时通过将柱塞杆相对于枪管锁定来重新使用注射器。 柱塞杆包括多个齿和设置在最远齿上的中间齿，以防止使用者反复地以不足以启动安全机构的剂量抽取，以及构造成打破施加过度力的可破裂部分。 可破裂部分优选地设置在柱塞杆的远端处，使得锁定元件的近端在更接近可断裂部分的位置处接合注射器筒和柱塞杆。 以这种方式，如果柱塞杆被扭转，则锁定元件抵抗否则将施加到可断裂部分的一些力。

公开(公告)号：WO2008019514A8

公开(公告)日：2009-03-12

申请号：PCT/CH2007000389

申请日：2007-08-10

Applicant: TECPHARMA LICENSING AG ,  HIRSCHEL JUERG ,  MOSER ULRICH ,  SCHRUL CHRISTIAN ,  TSCHIRREN MARKUS

Inventor： HIRSCHEL JUERG ,  MOSER ULRICH ,  SCHRUL CHRISTIAN ,  TSCHIRREN MARKUS

IPC: A61M5/24 ,  A61M5/315

CPC classification number: A61M5/2448 ,  A61M5/20 ,  A61M5/3146 ,  A61M5/31501 ,  A61M5/31511 ,  A61M5/31541 ,  A61M5/31553 ,  A61M5/31563 ,  A61M5/31583 ,  A61M5/31595 ,  A61M5/502 ,  A61M2005/2073 ,  A61M2005/2451 ,  A61M2005/3125

Abstract: The invention relates to an injection device comprising a housing (10) and an operating element (1) or coupling element. The operating element (1) or coupling element is mounted in the housing (10) in such a way that the operating element (1) or coupling element can be retained in a first position by a first holding connection (3e, 10b) and can be displaced into a second position that is axially offset relative to the first position after introducing an ampoule (13). The operating element (1) or coupling element can be retained by a second holding connection (3d, 10b) in the second position.

Abstract translation: 本发明涉及一种在注射装置，包括壳体（10）和操作元件（1）或耦合元件，其中所述操作元件（1）或在所述壳体（10）联接元件被安装成使得其从第一保持连接（3E，10b）的 第一位置可以被保持在第二引入管形瓶（13）的轴向偏移到第一位置，其中它（，10b的3D）可通过第二保持连接被保持在第二位置之后被移位。