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    PERMANENTLY WETTABLE SUPERABSORBENT FIBERS
    3.
    发明申请
    PERMANENTLY WETTABLE SUPERABSORBENT FIBERS 审中-公开
    永久耐用的超吸收纤维

    公开(公告)号：WO0170287A3

    公开(公告)日：2002-01-31

    申请号：PCT/US0108472

    申请日：2001-03-16

    Applicant: KIMBERLY CLARK CO

    Inventor： QIN JIAN ,  ZHANG XIAOMIN ,  RANGANATHAN SRIDHAR ,  LI YONG

    IPC: A61F13/53 ,  A61F5/44 ,  A61F13/15 ,  A61F13/49 ,  A61L15/60 ,  B01J20/32 ,  C08J7/12

    CPC classification number: C08J7/12 ,  A61F2013/530613 ,  A61L15/60 ,  B01J20/261 ,  B01J20/264 ,  B01J20/267 ,  B01J20/28014 ,  B01J20/28023 ,  B01J20/28035 ,  B01J20/3071 ,  B01J20/321 ,  B01J20/3217 ,  B01J20/3251 ,  B01J20/3287 ,  B01J20/3297 ,  B01J2220/68 ,  C08J2300/14

    Abstract: Methods of making permanently wettable superabsorbent material are provided. The permanently wettable superabsorbent materials made by the method have a floating time less than 30 seconds and cause a reduction in surface tension of saline less than about 30%. The methods involve treating the superabsorbent material with a surfactant solution. A surfactant is used that has at least one functional group that is reactive with the superabsorbent material and at least one non-reactive and hydrophilic functional group. The surfactant is applied to the superabsorbent material when the functional groups on the surface of the superabsorbent material areactivated. Permanently wettable superabsorbent materials, such as fibers, made by the method and disposable absorbent products comprising the permanently wettable superabsorbent material are also provided.

    Abstract translation: 提供永久润湿超吸收材料的制备方法。 通过该方法制备的永久可润湿的超吸收材料具有小于30秒的浮动时间，并且导致盐水的表面张力降低小于约30％。 所述方法包括用表面活性剂溶液处理超吸收材料。 使用具有至少一个与超吸收材料和至少一个非反应性和亲水性官能团反应的官能团的表面活性剂。 当超吸收材料的表面上的官能团被活化时，表面活性剂被施加到超吸收材料上。 还提供了通过该方法制造的永久可润湿的超吸收材料，例如纤维，以及包含永久可润湿的超吸收材料的一次性吸收产品。

    COATED MEDIA FOR CHROMATOGRAPHY
    5.
    发明申请
    COATED MEDIA FOR CHROMATOGRAPHY 审中-公开
    用于色谱的涂层介质

    公开(公告)号：WO1991011241A1

    公开(公告)日：1991-08-08

    申请号：PCT/US1991000325

    申请日：1991-01-16

    Applicant: PURDUE RESEARCH FOUNDATION

    Inventor： PURDUE RESEARCH FOUNDATION ,  VARADY, Laszlo ,  YANG, Yan, Bo ,  COOK, Steven, E. ,  REGNIER, Fred, E.

    IPC: B01D15/08

    CPC classification number: B01D67/0088 ,  B01D67/0093 ,  B01D2323/30 ,  B01J20/321 ,  B01J20/3212 ,  B01J20/3272 ,  B01J20/3276 ,  B01J20/3282 ,  B01J20/3285 ,  B01J20/3287 ,  B01J39/17 ,  B01J39/20 ,  B01J41/14 ,  Y10T428/2996 ,  Y10T428/31544

    Abstract: Disclosed are pellicular materials useful in contact with proteins and as chromatography media. Rigid, inert, hydrophobic, polymeric materials are exposed to a solution comprising a solute defining plural interspersed hydrophobic and hydrophilic domains. The solute molecules adsorb onto the surface of the substrate by hydrophobic - hydrophobic interaction with their hydrophilic domains extending outwardly away from the surface into the solution. The molecules are then crosslinked in place to produce a solvent and pH resistant coating which presents a hydrophilic surface sufficient to mask hydrophobic regions therebeneath. The multidomain adsorbing compounds may comprise reactive groups which subsequently can be derivatized using conventional techniques to produce chromatography materials useful for conducting affinity, size exclusion, cationic exchange, anionic exchange, neutral hydrophobic interaction, and other forms of chromatographic separations.

    Abstract translation: 公开了可用于与蛋白质和色谱介质接触的胶体材料。 将刚性，惰性，疏水的聚合材料暴露于包含限定多个疏水疏水和亲水结构域的溶质的溶液中。 溶质分子通过与其亲水畴的疏水 - 疏水相互作用吸附到衬底的表面上，所述亲水畴从表面向外延伸离开溶液。 然后将分子交联到适当位置以产生溶剂和耐酸性涂层，其提供足以掩蔽其下的疏水区域的亲水表面。 多畴吸附化合物可以包含反应性基团，其随后可以使用常规技术衍生化，以产生用于进行亲和力，尺寸排阻，阳离子交换，阴离子交换，中性疏水相互作用和其它形式的色谱分离的色谱材料。

    METHOD FOR THE CAPTURE OR REMOVAL OF AMYLOIDOGENIC PROTEINS
    9.
    发明申请
    METHOD FOR THE CAPTURE OR REMOVAL OF AMYLOIDOGENIC PROTEINS 审中-公开
    捕获或去除淀粉样蛋白的方法

    公开(公告)号：WO2013189991A1

    公开(公告)日：2013-12-27

    申请号：PCT/EP2013/062759

    申请日：2013-06-19

    Applicant: PRIONATIS AG

    Inventor： RUINATSCHA, Reto ,  HAGEN, Alexander

    IPC: B01J20/282 ,  C07K14/47 ,  G01N33/68

    CPC classification number: B01J20/28014 ,  B01J20/02 ,  B01J20/3204 ,  B01J20/3287 ,  C07K14/4711 ,  G01N33/6896 ,  G01N2333/4709

    Abstract: The present invention relates to methods for isolating, removing, concentrating, purifying and/or detecting amyloids, amyloidogenic proteins, fragments and/or derivatives thereof, and in particular to a method for the selective capture of amyloids, such as PrP sc . Another aspect of the invention is directed to devices for carrying out these inventive methods.

    Abstract translation: 本发明涉及用于分离，去除，浓缩，纯化和/或检测淀粉样蛋白，淀粉样蛋白形成蛋白，其片段和/或衍生物的方法，特别涉及用于选择性捕获淀粉样蛋白的方法，例如PrPsc。 本发明的另一方面涉及用于实施这些发明方法的装置。

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