公开(公告)号：WO2016176240A1

公开(公告)日：2016-11-03

申请号：PCT/US2016/029425

申请日：2016-04-27

Applicant: THE PROCTER & GAMBLE COMPANY

Inventor： LANT, Neil, Joseph ,  WOOD, Rebecca, Louise ,  GUMMEL, Jeremie, Robert Marcel

IPC: C11D3/386

CPC classification number: C11D3/38618 ,  C11D3/38627 ,  C11D3/38636 ,  C11D3/38645 ,  C11D11/0017 ,  C12Y301/21001 ,  C12Y301/30002 ,  C12Y302/01052

Abstract: A method of treating a textile in which a textile is contacted with an aqueous solution comprising a nuclease enzyme, preferably a deoxyribonuclease or ribonuclease enzyme and low levels of alkyl benzene sulphonate surfactant, and optionally rinsing and drying the textile.

Abstract translation: 一种处理纺织品的方法，其中织物与包含核酸酶，优选脱氧核糖核酸酶或核糖核酸酶和低水平烷基苯磺酸盐表面活性剂的水溶液接触，并任选地漂洗和干燥纺织品。

公开(公告)号：WO2017214244A1

公开(公告)日：2017-12-14

申请号：PCT/US2017/036307

申请日：2017-06-07

Applicant: THE PROCTER & GAMBLE COMPANY

Inventor： LANT, Neil, Joseph ,  HOLLINGSHEAD, Judith, Ann ,  FRANKENBACH, Gayle, Marie

IPC: C11D3/386 ,  C11D1/14 ,  C11D3/00 ,  C11D3/18 ,  C11D3/20 ,  C11D3/50

CPC classification number: C11D3/38636 ,  C11D1/143 ,  C11D1/22 ,  C11D1/29 ,  C11D3/0068 ,  C11D3/184 ,  C11D3/2034 ,  C11D3/2068 ,  C11D3/2072 ,  C11D3/2079 ,  C11D3/2093 ,  C11D3/2096 ,  C11D3/50 ,  C11D11/0017 ,  C12Y301/21001 ,  C12Y301/30002 ,  C12Y302/01052

Abstract: Cleaning compositions that include a nuclease enzyme and one or more malodor reduction materials. Methods of making and using such cleaning compositions. Use of malodor reduction materials.

Abstract translation: 包含核酸酶和一种或多种恶臭还原物质的清洁组合物。 制造和使用这种清洁组合物的方法。 使用恶臭减少材料。

公开(公告)号：WO2016176280A1

公开(公告)日：2016-11-03

申请号：PCT/US2016/029479

申请日：2016-04-27

Applicant: THE PROCTER & GAMBLE COMPANY

Inventor： LANT, Neil, Joseph ,  WOOD, Rebecca, Louise ,  GUMEL, Jeremie, Robert Marcel

IPC: C11D3/386

CPC classification number: C11D3/38636 ,  C12Y301/21001 ,  C12Y301/30002 ,  C12Y302/01052

Abstract: Method for treating a hydrophobically-modified textile with an aqueous solution of a nuclease enzyme, preferably a deoxyribonuclease or ribonuclease enzyme, rinsing and drying the textile. Use of the finishing step for improved cleaning with an aqueous solution of a nuclease enzyme, preferably a deoxyribonuclease or ribonuclease enzyme

Abstract translation: 用核酸酶，优选脱氧核糖核酸酶或核糖核酸酶的水溶液处理疏水改性纺织品的方法，漂洗和干燥纺织品。 使用整理步骤来改进用核酸酶酶，优选脱氧核糖核酸酶或核糖核酸酶的水溶液的清洗

公开(公告)号：WO2016065192A1

公开(公告)日：2016-04-28

申请号：PCT/US2015/056993

申请日：2015-10-22

Applicant: ROKA BIOSCIENCE, INC.

Inventor： BECKER, Michael, McClellan

IPC: C07H21/04 ,  C12Q1/68 ,  C12N9/16 ,  C12N9/22 ,  C12P19/34

CPC classification number: C12Q1/6823 ,  C12P19/30 ,  C12Q1/6818 ,  C12Q1/6834 ,  C12Q1/6837 ,  C12Y301/30002 ,  C12Q2521/301 ,  C12Q2563/131

Abstract: The present invention provides methods for detecting a target nucleic acid in a sample by, for example, incubating the target nucleic acid with a detection probe containing a nucleic acid sequence complementary to at least a portion of the target nucleic acid and a nuclease enzyme that specifically cleaves double-stranded nucleic acids. Hybridization between the detection probe and the target nucleic acid thereby leads to cleavage of the detection probe, releasing a portion of the probe attached to a detectable agent. The portions of the digested probes attached to the detectable agent can be separated from unbound probe and detected in order to determine the presence of the target nucleic acid in the sample. Thus, the invention enables rapid and accurate analysis of a sample for the presence of desired nucleic acid biomarkers.

Abstract translation: 本发明提供了通过例如将靶核酸与含有与目标核酸的至少一部分互补的核酸序列的检测探针和特异性的核酸酶来检测样品中的靶核酸的方法 切割双链核酸。 检测探针与目标核酸之间的杂交从而导致检测探针的裂解，释放附着于可检测试剂的探针的一部分。 连接到可检测试剂上的消化探针的部分可以与未结合的探针分离并检测，以便确定样品中靶核酸的存在。 因此，本发明可以快速准确地分析样品中所需核酸生物标志物的存在。

公开(公告)号：WO2019125804A1

公开(公告)日：2019-06-27

申请号：PCT/US2018/064718

申请日：2018-12-10

Applicant: BASF SE ,  TAN, Xuqiu

Inventor： TAN, Xuqiu ,  BARRETT, Kenneth ,  DENNIS, Jared ,  REN, Dongmei ,  DODGE, Corey ,  ZHANG, Bin

IPC: C12N9/22 ,  C12N15/10

CPC classification number: C12Y301/30002 ,  C12N9/22

Abstract: Disclosed herein are polypeptides having nuclease activity. Some of the polypeptides having nuclease activity were generated by an improved gene site mutagenesis ("GSSM") method or the tailored multi-site combinatorial assembly ("TMCA") method. Also disclosed are compositions and kits comprising the polypeptides having nuclease activity, and methods for making and using these polypeptides, compositions and kits.

公开(公告)号：WO2016176241A1

公开(公告)日：2016-11-03

申请号：PCT/US2016/029427

申请日：2016-04-27

Applicant: THE PROCTER & GAMBLE COMPANY

Inventor： LANT, Neil, Joseph ,  WOOD, Rebecca, Louise ,  GUMMEL, Jeremie, Robert Marcel

IPC: C11D3/386

CPC classification number: C11D3/38636 ,  C11D1/29 ,  C11D1/83 ,  C11D1/86 ,  C11D1/94 ,  C11D11/0017 ,  C12Y301/21001 ,  C12Y301/30002 ,  C12Y302/01052

Abstract: A cleaning composition comprising a nuclease enzyme, preferably a deoxyribonuclease and/or ribonuclease enzyme and a surfactant system comprising an anionic surfactant and a nonionic surfactant wherein the weight ratio of anionic to non-ionic surfactant is from 1.5:1 to 1:10.

Abstract translation: 一种包含核酸酶，优选脱氧核糖核酸酶和/或核糖核酸酶的清洁组合物和包含阴离子表面活性剂和非离子表面活性剂的表面活性剂体系，其中阴离子与非离子表面活性剂的重量比为1.5:1至1:10。