公开(公告)号：WO2021196469A1

公开(公告)日：2021-10-07

申请号：PCT/CN2020/105697

申请日：2020-07-30

Applicant: 鲁南厚普制药有限公司

Inventor： 张贵民 ,  关永霞 ,  范建伟

IPC: A61K36/889 ,  A61P29/00 ,  A61P1/14 ,  A61P31/14 ,  A61P11/00 ,  A61P31/16 ,  A61P31/20 ,  A61K2236/331 ,  A61K2236/39 ,  A61K2236/51 ,  A61K2236/53 ,  A61K35/64 ,  A61K36/31 ,  A61K36/346 ,  A61K36/428 ,  A61K36/634 ,  A61K36/73 ,  A61K36/734 ,  A61K36/752

Abstract: 小儿消积止咳制剂在制备治疗食积发热证药物中的应用及其制备方法，所述的小儿消积止咳制剂由山楂、槟榔、枳实、枇杷叶、全瓜蒌、连翘、莱菔子、葶苈子、蝉蜕和桔梗制成。具清热肃肺、消积止咳功效，具有退热和促进胃蛋白酶原分泌作用，有助于食物消化吸收，对食积发热证患者能达到消积退热、调理脾胃的治疗效果。

公开(公告)号：WO2022011322A1

公开(公告)日：2022-01-13

申请号：PCT/US2021/041190

申请日：2021-07-09

Applicant: CLEAN IMAGINEERING LLC ,  JACKSON, David, P. ,  JACKSON, Mackenzle, A. ,  LEE, John, J.

Inventor： JACKSON, David, P. ,  JACKSON, Mackenzle, A. ,  LEE, John, J.

IPC: E03F1/00 ,  E03F5/10 ,  E03F7/10 ,  A23L2/385 ,  A23L2/52 ,  A23L33/105 ,  A23V2002/00 ,  A61K2236/331 ,  A61K2236/333 ,  A61K2236/37 ,  A61K2236/51 ,  A61K2236/53 ,  A61K36/185 ,  B01D11/028 ,  B01D11/0288 ,  B01D11/0292 ,  B01D2011/007 ,  C12H3/00 ,  G01N1/4022 ,  G01N1/4055 ,  G01N11/00 ,  G01N2001/4061

Abstract: A semi-aqueous method for extracting a substance. The method involves combining a first liquid or solid substance containing an extract with a semi- aqueous solution containing a water-soluble or water-emulsifiable (WSWE) compound. Said WSWE compound selectively dissolves extract during a dense phase CO2 expansion and salting-out process, which is simultaneously co-extracted using said dense phase CO2, and desolvated to produce a CO2 salted- out solvent mixture containing extract. Said CO2 salted-out solvent mixture is treated using various secondary processes. The present invention is useful for producing extracts for use as additives in pharmaceuticals, nutraceuticals, cosmetics, beverages, or foods, and for quantitative analysis.

公开(公告)号：WO2022006367A2

公开(公告)日：2022-01-06

申请号：PCT/US2021/040036

申请日：2021-07-01

Applicant: RAMBUHEALTH CORP.

Inventor： ROJAS, Hider

IPC: A23L33/105 ,  A61K36/77 ,  A01N3/00 ,  A23L2/52 ,  A61K2236/15 ,  A61K2236/331 ,  A61K2236/51 ,  A61K2236/55

Abstract: A formulation for delivering one or more health benefits to a human post-consumption and a method to create the formulation are described. The formulation comprises a shell extract of Nephelium lappaceum in a form of a powder or a liquid and at least one material. The at least one material comprises a polysaccharide, a protein, a lipid, and/or a food grade compound. The one or more health benefits to the human include support or regulation of blood sugar, blood pressure, body weight, performance/recovery from sports, immune health, anti-aging, pain management, and/or joint health.

公开(公告)号：WO2021128232A1

公开(公告)日：2021-07-01

申请号：PCT/CN2019/128981

申请日：2019-12-27

Applicant: 广东省中医院

Inventor： 林爱华 ,  刘奕明 ,  王永刚 ,  陈宝婷

IPC: A61K36/8968 ,  A61P3/10 ,  A61P3/06 ,  A61P39/06 ,  A61P9/10 ,  A61K2236/331 ,  A61K2236/39 ,  A61K2236/51 ,  A61K2236/53

Abstract: 一种具有更高降糖活性的麦冬降解提取物。制备方法为：药材按液料比5～20，水提取1～3次，每次提取0.5～2小时，滤过，滤液浓缩至原料含量为0.5～2g/ml的浸膏，加乙醇使含醇量达75％～90％，沉淀蒸干得麦冬粗多糖；采用Sevage法脱蛋白纯化；纯化后加水充分溶解至透明状态，按料液比10:1加入2mol/L的酸，降解4～6h，加碱溶液至中性，超滤截留得分子量范围在500－2500之间的降解物，浓缩冷冻干燥，即得。与现有技术相比，上述提取物在降血糖方面具有更高的活性，明显优于麦冬粗多糖及其他现有方法获得的麦冬小分子多糖。产率可以高达95％以上，且方法简单易行，可规模化生产。