公开(公告)号：WO2023006854A1

公开(公告)日：2023-02-02

申请号：PCT/EP2022/071146

申请日：2022-07-28

Applicant: URGO RECHERCHE INNOVATION ET DEVELOPPEMENT ,  SZCZEPANIAK, Julie

Inventor： PEYNY, Emmanuelle ,  DUMEIX, Camille

IPC: A61K31/07 ,  A61K31/197 ,  A61K31/375 ,  A61K31/4188 ,  A61K31/455 ,  A61K31/51 ,  A61K31/519 ,  A61K31/525 ,  A61K31/593 ,  A61K31/714 ,  A61K33/04 ,  A61K33/24 ,  A61K33/26 ,  A61K33/30 ,  A61K33/32 ,  A61K33/34 ,  A61K36/258 ,  A61K31/355 ,  A61K36/355

Abstract: La présente invention a pour objet un produit de combinaison comprenant à titre de substances actives, au moins de la vitamine A, B1, B2, B3, B5, B8, B9, B12, C, D3, E, du zinc, du fer, du molybdène, du sélénium, du manganèse, du chrome, du cuivre et du ginseng, pour aider à retrouver la forme.

公开(公告)号：WO2022162667A1

公开(公告)日：2022-08-04

申请号：PCT/IL2022/050122

申请日：2022-01-27

Applicant: AMORPHICAL LTD.

Inventor： BEN, Yossi ,  BLUM, Yigal ,  ILLOS, Roni Antoine ,  ASHKENAZI, Ben

IPC: A61K9/14 ,  A61K9/16 ,  A61K9/10 ,  A61K47/02 ,  C01F11/18 ,  C01F5/24 ,  C08K3/26 ,  C08K3/10 ,  A61K33/10 ,  A61K33/26 ,  A61K33/32 ,  A61K33/34 ,  C08K3/08 ,  C08K3/22

Abstract: The present invention provides a composition including a particle, the particle includes a carbonate species of a first divalent metal and carbonate specie of a second divalent metal; wherein the particle is amorphous; wherein the first divalent metal and the second divalent metal are in an oxidation state of +2; and wherein the first divalent metal and the second divalent metal is each independently selected from: Ca, Zn, Fe, Cu, Co, Ni, Mn, Mg and Cr. Further provided is a composition including a divalent metal carbonate including any derivative thereof, and at least one stabilizing agent, wherein the divalent metal is selected from: Zn, Cu, Co, Mn, Mg, and Ni, optionally being characterized by BET between 20 and 200 m2/g. Pharmaceutical or nutraceutical compositions including the composition of particles disclosed, are also provided.

公开(公告)号：WO2022013743A1

公开(公告)日：2022-01-20

申请号：PCT/IB2021/056300

申请日：2021-07-13

Applicant: ADIFEED SP. Z O. O.

Inventor： IWINSKI, Hubert ,  ROZANSKI, Henryk

IPC: A61K33/24 ,  A61K33/26 ,  A61K33/30 ,  A61K33/32 ,  A61K33/245 ,  A61K36/54 ,  A61K36/882 ,  A61K36/8895 ,  A61K36/48 ,  A61K36/23 ,  A61K36/28 ,  A61K36/61 ,  A61K36/53 ,  A61K36/79 ,  A61K31/19 ,  A61K31/60 ,  A61K45/06 ,  A61P33/02 ,  A61K33/34

Abstract: The subject of invention is a veterinary composition comprising an essential oil, characterised in that the essential oil is selected from the group comprising anise oil, cinnamon oil, tarragon oil, clove oil, dill oil, Balsam of Peru, Ballota oil, star anise oil, calamus oil, and wherein the said essential oil is present in the form of a complex with a mixture of organic acids comprising four acids selected from the group comprising: valeric acid, isovaleric acid, lactic acid, butyric acid, acetic acid, propionic acid, formic acid, benzoic acid, pelargonic acid, salicylic acid, malonic acid, citric acid, phthalic acid, tartaric acid, oxalic acid, malic acid, shikimic acid, fumaric acid, mandelic acid, cinnamic or derivatives thereof and a metal selected from the group comprising molybdenum, cobalt, nickel, chromium, zinc, bismuth, copper, manganese, selenium, iron, their salts or oxides, for use in the treatment and/or prevention of protozoan diseases in animals. Another subject of invention is a method of manufacturing a veterinary composition for the treatment and/or prevention of protozoan diseases in animals, comprising an essential oil according to invention.

公开(公告)号：WO2022006426A1

公开(公告)日：2022-01-06

申请号：PCT/US2021/040135

申请日：2021-07-01

Applicant: AMERICAN REGENT, INC.

Inventor： ANYARAMBHATLA, Gopal ,  LAWRENCE, Richard ,  MARINKOVIC, Jasmina

IPC: A61K9/00 ,  A61K47/02 ,  A61K31/7004 ,  A61K33/00 ,  A61K33/04 ,  A61K33/06 ,  A61K33/22 ,  A61K33/24 ,  A61K33/30 ,  A61K33/32 ,  A61K33/34 ,  A61K47/10 ,  A61K47/20 ,  A61K9/0029 ,  A61P3/02

Abstract: Injectable compositions that can be added to parenteral nutrition are provided. In particular, a stable injectable composition is provided which includes water, and at least one of about 800 μg to about 4,000 μg of zinc, about 40 μg to about 400 μg of copper, from about 4 μg to about 90 μg of selenium, or from about 1 μg to about 80 μg of manganese per 1 mL of the injectable composition. Methods of preparing and using of the stable injectable composition are also provided.

公开(公告)号：WO2021195785A1

公开(公告)日：2021-10-07

申请号：PCT/CA2021/050447

申请日：2021-04-01

Applicant: THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO

Inventor： CHENG, Hai-Ling Margaret ,  SZULC, Daniel Andrzej ,  CHENG, Hai-Ying Mary

IPC: A61K49/14 ,  A61K49/08 ,  C12Q1/02 ,  C12Q1/6897 ,  C07K14/47 ,  C12N5/10 ,  G01R33/50 ,  A61B5/055 ,  A61K33/32 ,  B82Y5/00 ,  G01R33/5601

Abstract: The invention relates to the field of MRI imaging, particularly, to cellular tracking utilizing T1-weighted MRI, using overexpression of ferritin and a manganese – based contrast agent. The invention relates to a method of imaging a cell, comprising: overexpressing ferritin in said cell; subjecting the cell to a metal based magnetic resonance imaging (MRI) contrast agent; and imaging the cell utilizing T1-weighted MRI.

公开(公告)号：WO2021105361A1

公开(公告)日：2021-06-03

申请号：PCT/EP2020/083631

申请日：2020-11-27

Applicant: SOCIÉTÉ DES PRODUITS NESTLÉ S.A.

Inventor： SAMUEL, Tinu,Mary

IPC: A61K35/747 ,  A61K33/26 ,  A61K33/06 ,  A61K33/32 ,  A61K31/355 ,  A61K45/06

Abstract: The invention provide a mix or a nutritional compostion comprising a probiotic Lactobacillus Fermentum CECT-5716 and a n-3 fatty acid selected from the group consisting of docosahexaenoic acid (DHA) and 18:3 n-3 octadecatrienoic acid (alpha-linolenic acid); and optional a further nutrient or mineral selected from the group consisting of iron, manganese and magnesium, or combination of two of more thereof; for use in treating or preventing mastitis in a subject, preferably a pregnant or lactating woman.

公开(公告)号：WO2021007610A1

公开(公告)日：2021-01-21

申请号：PCT/AU2020/050710

申请日：2020-07-07

Applicant: CHEMVET AUSTRALIA PTY LTD

Inventor： GRANT, Murray, Graham

IPC: A61K31/714 ,  A61K31/198 ,  A61K33/24 ,  A61K33/30 ,  A61K33/32 ,  A61K33/34 ,  A61K47/10 ,  A23K50/10 ,  A23K20/20 ,  A23K20/174

Abstract: An aqueous injectable nutritional supplement composition for livestock, comprising: an EDTA complex of one or more trace elements; vitamin B 12 ; and a water-soluble liquid selected from glycols, glycol ethers and mixtures thereof.

公开(公告)号：WO2020247170A1

公开(公告)日：2020-12-10

申请号：PCT/US2020/033525

申请日：2020-05-19

Applicant: L'OREAL ,  BERNARD, Anne-Laure, Suzanne

Inventor： BERNARD, Anne-Laure, Suzanne ,  CHEN, Rebecca ,  PAN, Zhi

IPC: A61K8/19 ,  A61K8/27 ,  A61K8/22 ,  A61K8/92 ,  A61K33/32 ,  A61K33/30 ,  A61K33/34 ,  A61K33/40 ,  A61K47/06 ,  A61P17/02 ,  A61Q19/02

Abstract: A skin treatment system is disclosed including an oxygenate composition having at least one peroxide in a first aqueous phase and an activator composition, the activator composition including at least one alkaline booster in a second aqueous phase and at least one water-soluble peroxide decomposition catalyst in the second aqueous phase. Intermixing the oxygenate composition and the activator composition at least partially decomposes the at least one peroxide, liberating O 2 , and the skin treatment system in contact with keratinous tissue induces reduced irritation to the keratinous tissue relative to a comparative skin treatment system which is identical to the skin treatment system except for lacking the at least one water-soluble peroxide decomposition catalyst.

公开(公告)号：WO2020158607A1

公开(公告)日：2020-08-06

申请号：PCT/JP2020/002541

申请日：2020-01-24

Applicant: 学校法人同志社

Inventor： 人見　穣 ,  奥田　夏未

IPC: A61K31/409 ,  A61P39/06 ,  C08G65/337 ,  A61K47/60 ,  A61K33/32

Abstract: 新規な親水性ポリマー架橋網目ヒドロゲルを提供するとともに、過剰にROSが存在する場所にてROSを感受して抗酸化剤を放出する活性酸素抑制剤を提供する。マンガンテトラキス(4-カルボキシフェニル)ポルフィリンと、マンガンテトラキス(4-カルボキシフェニル)ポルフィリン同士を接続するポリエチレングリコール鎖を有するリンカーLと、を含み、マンガンテトラキス(4-カルボキシフェニル)ポルフィリンを網目内に有する親水性ポリマー架橋網目ヒドロゲルである。

公开(公告)号：WO2019172739A1

公开(公告)日：2019-09-12

申请号：PCT/MX2018/000034

申请日：2018-04-09

Applicant: INSTITUTO TECNOLÓGICO JOSÉ MARIO MOLINA PASQUEL Y HENRIQUEZ

Inventor： TORRES ÁVALOS, Gerardo Alonso ,  LOZANO GONZÁLEZ, Edith Ariadna

IPC: A61K8/26 ,  A61K8/27 ,  A61K8/28 ,  A61K31/28 ,  A61K31/262 ,  A61K31/30 ,  A61K31/315 ,  A61K31/32 ,  A61K33/06 ,  A61K33/24 ,  A61K33/30 ,  A61K33/32 ,  A61K33/34 ,  A61P31/12

Abstract: La presente invención consiste en una suspensión antiviral para tratamiento de fibras que comprende por lo menos una sal orgánica de un metal mono, di o trivalente con actividad antiviral suspendida en una solución reguladora del pH ácido; el proceso para obtenerla; y el proceso para obtener fibras antivirales empleando dicha suspensión antiviral.