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    ANTIBACTERIAL COMPOSITIONS COMPRISING COPPER OXO-HYDROXIDE NANOPARTICLES AND THEIR USES AS BIOCIDAL AGENTS
    5.
    发明申请
    ANTIBACTERIAL COMPOSITIONS COMPRISING COPPER OXO-HYDROXIDE NANOPARTICLES AND THEIR USES AS BIOCIDAL AGENTS 审中-公开
    包含铜氧化物纳米粒子的抗菌组合物及其作为生物化学剂的用途

    公开(公告)号：WO2016170152A1

    公开(公告)日：2016-10-27

    申请号：PCT/EP2016/059074

    申请日：2016-04-22

    申请人： MEDICAL RESEARCH COUNCIL

    发明人： BASTOS, Carlos André Passos ,  BRUGGRABER, Sylvaine Francoise Aline ,  FARIA, Nuno, Jorge, Rodrigues ,  POWELL, Jonathan, Joseph

    IPC分类号： A61K31/30 ,  A61P31/00

    CPC分类号： A61K31/30 ,  A61K9/0017 ,  A61K9/0024 ,  A61P31/04

    摘要： Antibacterial compositions comprising nanoparticles formed from copper oxo-hydroxide are described that are capable of delivering biocidal concentrations of copper, typically in the form of free copper ions (Cu 2+ ). The nanoparticle compositions generally comprise small particles, typically having mean diameters in the range of 1-100nm, having comparatively high surface area-to-volume ratio and enhanced reactivity compared to the corresponding bulk counterpart materials and which are sufficiently labile to release the free copper efficiently.

    摘要翻译： 描述了包含由氧羰基氢氧化物形成的纳米颗粒的抗菌组合物，其能够递送杀生物浓度的铜，通常为游离铜离子（Cu 2+）的形式。 纳米颗粒组合物通常包含通常具有在1-100nm范围内的平均直径的小颗粒，具有相对较高的表面积 - 体积比并且与相应的大量对应材料相比具有增强的反应性，并且它们足够不稳定地释放游离铜 有效率的。

    TOPICAL COPPER ION TREATMENTS AND METHODS OF MAKING TOPICAL COPPER ION TREATMENTS FOR USE IN VARIOUS ANATOMICAL AREAS OF THE BODY
    6.
    发明申请
    TOPICAL COPPER ION TREATMENTS AND METHODS OF MAKING TOPICAL COPPER ION TREATMENTS FOR USE IN VARIOUS ANATOMICAL AREAS OF THE BODY 审中-公开
    局部铜离子处理及制备局部铜离子处理方法，用于各种不同的解剖学领域

    公开(公告)号：WO2014151350A1

    公开(公告)日：2014-09-25

    申请号：PCT/US2014/025530

    申请日：2014-03-13

    申请人： CDA RESEARCH GROUP, INC. ,  ABBOTT, Chun, Lim ,  ABBOTT, Dominic, C.

    发明人： ABBOTT, Chun, Lim ,  ABBOTT, Dominic, C.

    IPC分类号： A61K31/30

    CPC分类号： A61K9/0034 ,  A61K9/0031 ,  A61K9/02 ,  A61K9/06 ,  A61K9/08 ,  A61K9/12 ,  A61K9/7084 ,  A61K33/34 ,  A61L17/005 ,  A61L24/02

    摘要： A topical copper ion treatment in basic form comprises a copper ion- containing solution composed of a biocompatible solution containing copper ions obtained by leaching of the copper ions from copper metal into the solution. The copper ion-containing solution can be combined with various carriers to form various forms of the copper ion treatment including creams, gels, lotions, foams, pastes, tampons, solutions, suppositories, body wipes, wound dressings, skin patches, and suture material. A method of making the copper ion-containing solution involves placing solid copper metal in a quantity of a biocompatible solution and maintaining the solution at a specified temperature for a predetermined period of time during which copper ions leach from the copper metal into the solution, and thereafter separating the solution from the solid copper metal.

    摘要翻译： 碱性形式的局部铜离子处理包括由含有铜离子的生物相容性溶液组成的含铜离子溶液，其通过将铜离子从铜金属浸出到溶液中而获得。 含铜离子的溶液可以与各种载体组合以形成各种形式的铜离子处理，包括乳膏，凝胶，洗剂，泡沫，糊剂，棉塞，溶液，栓剂，身体擦拭物，伤口敷料，皮肤贴片和缝合材料 。 制造含有铜离子的溶液的方法包括将固体铜金属置于一定量的生物相容性溶液中，并将溶液保持在规定温度下一定时间，在此期间铜离子从铜金属浸出到溶液中，以及 然后将溶液与固体铜金属分离。

    MINERAL COLLAGEN CHELATES AND METHODS OF MAKING AND USING SAME
    8.
    发明申请
    MINERAL COLLAGEN CHELATES AND METHODS OF MAKING AND USING SAME 审中-公开
    矿物胶原蛋白及其制备和使用方法

    公开(公告)号：WO2007044945A3

    公开(公告)日：2009-04-30

    申请号：PCT/US2006040298

    申请日：2006-10-13

    申请人： GU JENNIFER L ,  LEE EDWARD

    IPC分类号： A01N55/02 ,  A61K31/30

    CPC分类号： C12P21/06 ,  C07K14/78

    摘要： Collagen peptide chelated mineral products, pharmaceutical formulations thereof and methods for preparing same are provided. Also provided is a method for generating the optimal size of collagen peptide for optimum mineral chelation as well as optimum biological function for supporting bone health and joint health. Also disclosed are methods of increasing bone density/preventing osteoporosis, of reducing joint pain and/or joint deterioration from osteoarthritis, degenerative joint disease, joint defect, and rheumatoid arthritis.

    摘要翻译： 提供胶原肽螯合矿物产品，其药物制剂及其制备方法。 还提供了用于产生用于最佳矿物螯合的胶原肽的最佳尺寸以及用于支持骨骼健康和关节健康的最佳生物学功能的方法。 还公开了增加骨密度/预防骨质疏松症，减轻关节疼痛和/或骨关节炎，退行性关节病，关节缺损和类风湿性关节炎的关节恶化的方法。