公开(公告)号：WO2022149063A1

公开(公告)日：2022-07-14

申请号：PCT/IB2022/050044

申请日：2022-01-04

Applicant: JUBILANT DRAXIMAGE INC.

Inventor： BAIDA, Chadi ,  SIEWKO, Dominic

IPC: G21F5/06 ,  A61J1/20 ,  A61M36/08

Abstract: Provided are systems for filling containers with radioactive and/or other types of potentially hazardous materials. In some aspects, the systems include a shielding material that substantially defines a chamber and, preferably, substantially blocks radioactivity, a conduit extending from outside to into the chamber, and a unit that is disposed in the chamber proximal to the conduit and is adapted to receive a capsule through the conduit. The systems of the present disclosure can further comprise a syringe, a syringe controller that is disposed in the dispensing chamber and adapted to meter an aliquot from a radioactive stock solution and inject the aliquot into the capsule or a vial.

公开(公告)号：WO2020252564A1

公开(公告)日：2020-12-24

申请号：PCT/CA2020/050790

申请日：2020-06-10

Applicant: JUBILANT DRAXIMAGE INC.

Inventor： SIEWKO, Dominic ,  KAUFMAN, James A. ,  BISSONNETTE, Suzanne ,  SANTOPIETRO, Riccardo ,  DONNELLY, Paul

IPC: A61M36/08 ,  A61M36/04 ,  A61M5/142

Abstract: Syringe shield for a syringe containing a radioactive solution and infusion pump system for delivering the radioactive solution to a patient. The syringe includes a barrel containing the radioactive solution, a plunger comprising a plunger flange and a plunger stem, and a tip. The syringe shield is made from a radiation-shielding material and includes: a shield body having a first open end and a second open end. The syringe is insertable in the syringe shield such that the plunger is extendable through the first open end and the tip is adjacent the second open end.

公开(公告)号：WO2011124780A2

公开(公告)日：2011-10-13

申请号：PCT/FR2011/000168

申请日：2011-03-24

Applicant: ISP SYSTEM ,  SAUVAGEOT, Paul ,  BRESCON, David

Inventor： SAUVAGEOT, Paul ,  BRESCON, David

IPC: G21F5/018 ,  A61M5/178 ,  B65B3/00 ,  A61M36/08

CPC classification number: G21F5/018 ,  A61M5/1782 ,  A61M5/1785 ,  B65B3/003

Abstract: L'invention concerne un dispositif (1) de préparation d'une seringue (S) équipée d'une aiguille (7), ladite seringue (S) étant logée dans un fourreau (F) de protection et de préhension, ledit dispositif étant intégré dans une enceinte blindée (3) munie d'une ouverture (4, 5, 6) d'accès à l'intérieur de celle-ci, ledit dispositif comprenant en outre un bâti (2) en liaison avec un poste (P) de mise en place ou d'enlèvement de la seringue et de son fourreau, le bâti (2) étant en liaison avec un poste de remplissage (8) de la seringue par un fluide radioactif, caractérisé en ce que ledit dispositif comprend un organe de transfert (T) de la seringue (S) commandé en translation horizontale et en rotation par rapport au bâti (2), l'organe de transfert entraînant la seringue (S) disposée dans son fourreau (F) depuis sa position initiale au poste (P) dans au moins une position de remplissage au poste (8) de remplissage et la ramenant dans la position initiale au poste (P) de mise en place ou d'enlèvement.

Abstract translation: 本发明涉及一种用于制备装有针（7）的注射器（S）的装置（1），所述注射器（S）容纳在用于保护和夹紧的护套（F）中，所述装置集成在金属 - 具有用于接近其内部的开口（4,5,6）的所述包层壳体（3），所述装置还包括连接到站（P）的框架（2），用于放置或移除注射器及其护套 ，所述框架（2）连接到用于向所述注射器填充放射性流体的加注站（8），其特征在于，所述装置包括用于注射器（S）的转移构件（T），被控制在水平平移中 驱动相对于所述框架（2）的转动构件，所述传递构件驱动设置在其护套（F）中的注射器（S）从其在工位（P）的初始位置到位于加油站（8）处的至少一个填充位置 ）并将其返回到站（P）的初始位置以进行放置或移除。

公开(公告)号：WO2012061348A3

公开(公告)日：2012-07-26

申请号：PCT/US2011058727

申请日：2011-11-01

Applicant: CIVATECH ONCOLOGY ,  HOEDL SETH A

Inventor： HOEDL SETH A

IPC: A61N5/00 ,  A61M36/04 ,  A61M36/06 ,  A61M36/08

CPC classification number: A61N5/1001 ,  A61N2005/1005 ,  A61N2005/1094

Abstract: A brachytherapy device includes a sealed housing having a radioactive material therein, and at least one shielding member extending away from the housing and configured to provide radiation shielding on at least one side of the housing.

Abstract translation: 近距离放射治疗装置包括其中具有放射性材料的密封壳体，以及至少一个屏蔽构件，该屏蔽构件远离壳体延伸并且构造成在壳体的至少一侧上提供辐射屏蔽。

公开(公告)号：WO2009124257A3

公开(公告)日：2010-01-07

申请号：PCT/US2009039482

申请日：2009-04-03

Applicant: MOLECULAR INSIGHT PHARM INC ,  YOKELL DANIEL L

Inventor： YOKELL DANIEL L

IPC: A61M36/08

CPC classification number: A61M5/1407 ,  A61M5/007 ,  A61M5/1415 ,  A61M5/1785 ,  A61M2209/08 ,  G21F5/015 ,  G21G1/0005 ,  G21H5/02

Abstract: Described herein are methods and devices for infusion of a radioactive compound, such as yttrium-90 radiolabeled somatostatin peptide or analog. A radiation shield defining a shielded cavity suitable for storing a radioactive substance includes a first aperture providing external access to the shielded cavity and a second aperture suitable for transferring a dosage vial into and out of the shielded cavity. A removable shielded plug and panel are adapted to shield respective apertures of the radiation shield. At least one dose of a radiolabeled compound stored in a vial in the radiation shield is delivered through a fluid communication channel at a rate of about 500 mL/hour. The fluid communication channel is washed after delivery, such that the process substantially reduces radiation exposure during infusion of the radiolabeled compound into a patient.

Abstract translation: 本文描述了用于输注放射性化合物的方法和装置，例如钇-90放射性标记的生长抑素肽或类似物。 限定适于存储放射性物质的屏蔽空腔的辐射屏蔽包括提供对屏蔽空腔的外部通路的第一孔和适于将剂量小瓶转入和移出屏蔽腔的第二孔。 可拆卸屏蔽插头和面板适于屏蔽辐射屏蔽的各个孔。 储存在辐射屏蔽中的小瓶中的至少一剂放射性标记化合物以约500mL /小时的速率通过流体连通通道输送。 流体连通通道在输送后洗涤，使得该过程在将放射性标记的化合物输注入患者期间显着降低辐射暴露。

公开(公告)号：WO03088269A2

公开(公告)日：2003-10-23

申请号：PCT/GB0205604

申请日：2002-12-11

Applicant: AMERSHAM PLC ,  WEISNER PETER STEWART ,  FORREST TERENCE ROBERT FREDERI

Inventor： WEISNER PETER STEWART ,  FORREST TERENCE ROBERT FREDERI

IPC: G21G1/00 ,  A61M36/08 ,  G21G4/08

CPC classification number: G21G4/08

Abstract: A device for producing a fluid containing a radioactive constituent, comprising a shielded chamber (5) with an opening for receiving an isotope container (6) housing a radioactive isotope (7); a chamber closure (18) adapted for cooperating with and closing the chamber opening; a first fluid port comprising a first hollow needle projecting into the shielded chamberfrom the chamber closure for fluid communication with the isotope container; a second fluid port comprising a second hollow needle projecting into the shielded chamber from the closed end of the chamber opposite the chamber closure for fluid communication with the isotope container; first and second compressible buffers (28, 29) mounted so as to surround at least partially the respective first and second hollow needles (12, 13), each buffer providing an outer surface for contact with opposed ends of the isotope container; and a spacer of a predetermined thickness associated with one or each of the first and second compressible buffers for determining the positioning of the isotope container within the shielded chamber.

Abstract translation: 一种用于产生含有放射性成分的流体的装置，包括带有用于容纳放射性同位素（7）的同位素容器（6）的开口的屏蔽室（5）; 腔室封闭件（18），其适于与腔室开口协作并且关闭腔室开口; 第一流体端口，所述第一流体端口包括第一中空针头，所述第一中空针头从所述腔室闭合件伸入所述屏蔽室中以与所述同位素容器流体连通; 第二流体端口，所述第二流体端口包括第二中空针头，所述第二中空针头从与所述腔室闭合件相对的所述腔室的封闭端伸入所述屏蔽腔室中， 第一和第二可压缩缓冲器（28,29），其安装成至少部分地围绕相应的第一和第二中空针（12,13），每个缓冲器提供用于与同位素容器的相对端接触的外表面; 以及与第一和第二可压缩缓冲器中的一个或每一个相关联的预定厚度的间隔件，用于确定同位素容器在屏蔽室内的定位。

公开(公告)号：WO01010487A1

公开(公告)日：2001-02-15

申请号：PCT/US2000/021427

申请日：2000-08-04

IPC: A61M5/178 ,  A61M36/08 ,  A61N5/10

CPC classification number: A61M5/1785 ,  A61N5/1007 ,  Y10S128/919 ,  Y10S604/905

Abstract: An infuser for transferring hazardous treatment fluids to and from a medical application includes a spill containing housing having a medical application connecting element and a syringe seat. The syringe seat of the infuser leads to a syringe connecting element that provides a fluid coupling between the syringe and a fluid passage leading to the medical application connecting element. The interior of the housing can be sealed against leaks, for example, by providing the housing in two portions with a gasket provided between the portions. A fluid tight coupling between the syringe and the interior of the housing may be created by integrally forming a septum with the gasket and coupling the syringe with the syringe connecting element through the septum. The infuser can also be provided with two syringe seats so that two different fluids can be transferred. In one embodiment, a second syringe connecting element is provided in fluid-tight communication with a second fluid passage. A method for transferring fluids to and from a medical application is also disclosed.

Abstract translation: 用于向医疗应用传送危险处理液的输液器包括具有医疗应用连接元件和注射器座的溢出容纳壳体。 注射器的注射器座通向注射器连接元件，其提供注射器与通向医疗应用连接元件的流体通道之间的流体联接。 壳体的内部可以被密封以防止泄漏，例如通过将壳体设置在两部分之间，垫圈设置在这些部分之间。 注射器和外壳内部之间的流体紧密联接可以通过用垫圈一体地形成隔膜并将注射器与注射器连接元件通过隔膜联接而形成。 输液器还可以设置两个注射器座，以便可以传送两种不同的流体。 在一个实施例中，第二注射器连接元件设置成与第二流体通道流体密封连通。 还公开了将流体输送到医疗应用的方法。

公开(公告)号：WO2020061705A1

公开(公告)日：2020-04-02

申请号：PCT/CA2019/051381

申请日：2019-09-26

Applicant: KAMEN, Robert

Inventor： KAMEN, Robert ,  SEGRT, Mico ,  PETROVIC, Rasho

IPC: A61M36/08 ,  A61M5/32

Abstract: A shield for a syringe containing biohazardous material includes an elongate body comprising a compartment extending longitudinally therethrough from a body cold end to a body hot end, the compartment dimensioned to receive a syringe barrel; a cold end cover dimensioned to receive and enclose a syringe plunger extending beyond the body cold end, the cold end cover attachable at the body cold end for enclosing the compartment and the syringe plunger at the body cold end thereby to shieldingly contain the biohazardous material in the syringe at the body cold end; and a hot end cover attachable at the body hot end for at least enclosing the compartment at the body hot end thereby to shieldingly contain the biohazardous material in the syringe at the body hot end.

公开(公告)号：WO2018132891A1

公开(公告)日：2018-07-26

申请号：PCT/CA2017/050689

申请日：2017-06-06

Applicant: KAMEN, Robert

Inventor： KAMEN, Robert

IPC: G21F5/12 ,  A61J1/20 ,  A61M36/08 ,  G21F5/14

Abstract: A pig for transporting a container of biohazardous material, wherein the container comprises a bottle and a bottle closure. The pig includes a body comprising a compartment dimensioned to receive the container; a cap attachable to the body for closing the compartment thereby to shieldingly contain the biohazardous material in the container, the cap including: a collar sealingly engageable with the body and having an opening therethrough in communication with the compartment thereby to provide access to the bottle closure; a cap closure sealingly engageable within the opening of the collar to sealingly close the opening and cause the bottle closure to be gripped within the cap, wherein when the collar is disengaged from the body while the cap closure is engaged within the opening of the collar, the container remains gripped within the cap. A system for transporting and providing access to a biohazardous material includes the pig and an insert sealingly engageable within the opening of the collar while the cap closure is removed, the insert comprising an injection port extending fully therethrough in axial alignment with the compartment thereby to guide insertion of a syringe centrally through the container closure and into the container. A compression member for insertion into a pig for transporting a container of biohazardous materials is also provided. The compression member includes a flange; and spaced apart fingers supported by the flange and together forming a circle, the fingers each having a substantially vertical component extending upwards from the flange and a substantially horizontal component extending inwards from an end of the substantially vertical component distal from the flange, the spaced apart fingers resiliently compressible inwardly against the container by compressive engagement of a complementary annulus of the pig into which the compression member is dimensioned to be inserted.

公开(公告)号：WO2018112625A1

公开(公告)日：2018-06-28

申请号：PCT/CA2017/051547

申请日：2017-12-20

Applicant: THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING / MCGILL UNIVERSITY

Inventor： ENGER, Shirin Abbasi Nejad ,  FAMULARI, Gabriel

IPC: A61M36/04 ,  A61M36/08 ,  A61N5/10

Abstract: A delivery system and method for radiation shielded brachytherapy comprises a drive assembly, and a plurality of shield assemblies, pivotally mounted to the drive assembly, each having a tubular body defining an outer surface and a bore longitudinally extending between opposite ends of the tubular body. Each of the shield assemblies comprises radiation shielding material extending about a circumferential portion of the tubular body and disposed between the outer surface and the cavity. An interlocking system is operatively mounted to the rotating assembly, and engages a group of the plurality of shield assemblies. The interlocking system is configured for transmitting a rotational input received from a driving mechanism to the group of shield assemblies, for synchronously rotating each shield assembly of the group about their respective longitudinal axis.