SYNTHESIS OF POLYSACCHARIDE COVERED SUPERPARAMAGNETIC OXIDE COLLOIDS
    2.
    发明申请
    SYNTHESIS OF POLYSACCHARIDE COVERED SUPERPARAMAGNETIC OXIDE COLLOIDS 审中-公开
    多糖覆盖超氧化物胶体的合成

    公开(公告)号:WO1995005669A1

    公开(公告)日:1995-02-23

    申请号:PCT/US1993007682

    申请日:1993-08-12

    CPC classification number: H01F1/445 A61K49/1809 A61K49/1863

    Abstract: In a method for the synthesis of a colloid including a superparamagnetic metal oxide coated with a polymer, an acidic solution of a metal salt and a polymer may be cooled, and then neutralized by the controlled addition of a cool solution of a base, and may then be converted, by the application of heat, to a homogenous superparamagnetic metal oxide colloid. According to a preferred embodiment, the polymer may be a polysaccharide. In a further embodiment of the invention, the polysaccharide may be dextran and the metal salt may be ferrous and ferric salts, which produces, according to the methods of the invention, a superparamagnetic iron oxide colloid with an extended plasma half-line.

    Abstract translation: 在合成包含用聚合物涂覆的超顺磁金属氧化物的胶体的方法中,可以将金属盐和聚合物的酸性溶液冷却,然后通过控制加入碱的冷溶液中和,并且可以 然后通过加热转化成均匀的超顺磁金属氧化物胶体。 根据优选的实施方案,聚合物可以是多糖。 在本发明的另一个实施方案中,多糖可以是葡聚糖,并且金属盐可以是亚铁和铁盐,其根据本发明的方法产生具有延长的等离子体半线的超顺磁性氧化铁胶体。

    SUPERPARAMAGNETIC LIQUID COLLOIDS
    4.
    发明申请
    SUPERPARAMAGNETIC LIQUID COLLOIDS 审中-公开
    超级液体胶囊

    公开(公告)号:WO1990015423A1

    公开(公告)日:1990-12-13

    申请号:PCT/US1990003177

    申请日:1990-06-05

    CPC classification number: H01F1/442 H01F1/44

    Abstract: Electrically-conductive superparamagnetic liquid colloids and methods for making and using them are described. The magnetic liquid colloids contain magnetic particles coated with a conductive, organo-metallic compound, which impart the magnetic and conductive characteristics to the fluid. The coated magnetic particles are dispersed in a carrier fluid that gives the fluid viscosity, flow and vapor pressure properties.

    Abstract translation: 介绍了导电超顺磁性液体胶体及其制备和使用方法。 磁性液体胶体含有涂覆有导电性有机金属化合物的磁性颗粒,其赋予流体磁性和导电特性。 涂覆的磁性颗粒分散在载体流体中,其赋予流体粘度,流动和蒸气压特性。

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