US10982303B2
There is provided a coated steel product having a steel product and a coating layer including a Zn—Al—Mg alloy layer disposed on a surface of the steel product, in which the Zn—Al—Mg alloy layer has a Zn phase, the Zn phase contains a Mg—Sn intermetallic compound phase, and the coating layer consists of Zn: more than 65.0%, Al: from more than 5.0% to less than 25.0%, Mg: from more than 3.0% to less than 12.5%, Sn: 0.1% to 20.0% in terms of percent (%) by mass, given amounts of optional elements, and impurities, and has a chemical composition that satisfies the following Formulas 1 to 5: Bi+In
US10982296B2
An aluminium-zinc-hot-dipped and colour-coated steel plate having yield strength of ≥500 MPa and a high elongation and a manufacturing method thereof, with the chemical components in mass percentage of a substrate of the steel plate being: 0.07-0.15% of C, 0.02-0.5% of Si, 1.3-1.8% of Mn, N≤0.004%, S≤0.01%, Ti≤0.15%, Nb≤0.050%, and the balance being Fe and other inevitable impurities, and meanwhile satisfying the conditions of: (C+Mn/6)≥0.3%; Mn/S≥150; Nb satisfying 0.01%≤(Nb-0.22C-1.1N)≤0.05% where no Ti is contained; Ti satisfying 0.5≤Ti/C≤1.5 where no Nb is contained; and 0.04%≤(Ti+Nb)≤0.2% where Ti and Nb are added in combination. The steel plate has a tensile strength of ≥550 MPa, an elongation after fracture of ≥15%, a good strength and toughness and an excellent corrosion resistance.
US10982295B2
The present invention discloses a strain S. cerevisiae M 2016785 producing high concentration of β-phenylethanol and application thereof, and belongs to the technical field of industrial microorganisms. The strain S. cerevisiae M 2016785 producing high concentration of β-phenylethanol according to the present invention was deposited in China Center for Type Culture Collection (CCTCC) on Dec. 26, 2016 with the accession number OF CCTCC NO: M 2016785. The strain of the present invention has the high β-phenylethanol production capacity, and is applied in the fermentation of Huangjiu, the fermentation of cooking wine, the brewing of vinegar, the fermentation of soybean sauce and the fermentation of Baijiu, in which the content of β-phenylethanol can reach 410 mg/L, 450 mg/L, 300 mg/L, 200 mg/L, 110 mg/L and 370 mg/L respectively, and effectively increases the concentration of the flavor substance such as 2-phenylethyl acetate. The yeast strain of the present invention has good fermentation performance, obviously improves the β-phenylethanol content in the fermented product, and improves the quality of the fermented product, and thus has broad application prospects.
US10982292B2
This invention is intended to develop many DNA markers in plants of the genus Fragaria and to evaluate anthracnose resistance with high accuracy with the use of such many DNA markers. The markers associated with anthracnose resistance in plants of the genus Fragaria each comprise a continuous nucleic acid region sandwiched between the nucleotide sequence as shown in SEQ ID NO: 1 and the nucleotide sequence as shown in SEQ ID NO: 10 in the chromosome of a plant of the genus Fragaria.
US10982291B2
The specification relates generally to methods of detecting, diagnosing, and/or identifying pathogens, e.g., infectious disease pathogens and determining their drug sensitivity and appropriate methods of treatment. This invention also relates generally to methods of monitoring pathogen infection in individual subjects as well as larger populations of subjects.
US10982284B2
Disclosed are compositions and methods for assessing the apoptosis and survival BAD phosphorylation pathway (BAD pathway); and/or (2) the cell cycle role of APC in cell cycle regulation pathway (APC pathway); and/or (3) the transcription CREB pathway (CREB pathway) and for using these pathways to assess, treat, monitor, prognose, diagnose, etc. subjects with cancer. Also disclosed are compositions and methods for identifying molecular pathways that are common to one or more chemotherapeutic agents for the treatment of an oncological disorder, for screening for compounds or agents that can be used to treat ovarian cancer, and for selecting for compounds or agents that can enhance the cytotoxic response of cisplatin, carboplatin, and/or paclitaxel against a cancer cell, such as an ovarian cancer cell or cell line.
US10982282B2
Disclosed herein are compositions and methods useful for the diagnosis, assessment, and characterization of endometriosis in a subject in need thereof, based upon the expression level of at least one miRNA that is associated with endometriosis.
US10982278B2
The present disclosure generally relates to methods and compositions of linking, amplifying, and sequencing nucleic acid molecules. Also disclosed is the use of 5′-5′linked oligonucleotides for linking nucleic acid molecules for sequencing of the ends of long nucleic acid template molecules, or for sequencing polymorphism or different target genes or different RNAs simultaneously.
US10982277B2
Some embodiments described herein relate to modified nucleotide and nucleoside molecules with novel 3′-hydroxy protecting groups. Also provided herein are methods to prepare such modified nucleotide and nucleoside molecules and sequencing by synthesis processes using such modified nucleotide and nucleoside molecules.
US10982270B2
The invention concerns a method for detecting isothermal loop-mediated (LAMP) amplification of a target nucleic acid sequence which is based on the fluorescence resonance energy transfer (FRET) mechanism. The invention also concerns a set of oligonucleotides and a kit adapted for carrying out the LAMP-FRET method of the invention.
US10982260B2
Systems and methods for nucleic acid sequencing are provided. Nucleic acid is fixed in double-stranded linearized stretched form on a test substrate before being denatured into to single stranded form on the substrate to obtain adjacent fixed first and second strands of the nucleic acid. The strands are exposed to a respective pool of a respective oligonucleotide probe in a set of probes under conditions allowing for probes to form a heteroduplex with a corresponding complementary portion of the fixed first or second strand thereby giving rise to a respective instance of optical activity. An imager measures a location and duration on the substrate of this optical activity. The exposing and measuring is repeated for probes in the set of probes thereby obtaining a plurality of sets of positions. The nucleic acid sequence is determined from the plurality of sets of positions through compilation of the positions in the sets.
US10982252B2
Bacterial systems for analyzing ubiquitination of proteins is disclosed herein. Kits for analyzing the ubiquitination and methods for carrying out the analysis are also disclosed.
US10982251B2
A method of making an electrochemical sensor strip that includes: depositing a first electrode on a base; depositing a second electrode on the base; applying a first layer onto the first electrode; and applying a second layer onto the second electrode. The first layer includes an oxidoreductase and a mediator. The second layer includes a soluble redox species.
US10982248B2
Disclosed are methods for amplifying a nucleic acid target region using an amplification oligomer comprising a target-binding segment and a heterologous displacer tag situated 5′ to the target-binding segment. Initiation of an amplification reaction from the tagged amplification oligomer produces an amplicon comprising the displacer tag, such that once the complement of the displacer tag has been incorporated into a second amplicon, a displacer oligonucleotide having a sequence substantially corresponding to the displacer tag sequence is used to participate in subsequent rounds of amplification for displacement of an extension product primed from a site within the second amplicon 5′ to the displacer priming site. Also disclosed are related kits and reaction mixtures comprising the displacer-tagged amplification oligomer and corresponding displacer oligonucleotide.
US10982247B2
This invention relates to mutant DNA polymerases having an enhanced template discrimination activity compared with the corresponding unmodified DNA polymerase counterparts, wherein the amino acid sequence of the mutant DNA polymerase includes at least one substitution at residue positions structurally and functionally homologous or orthologous positions 783 or 784 of an unmodified Taq DNA polymerase.
US10982242B2
The present invention relates to an optimized fermentation process of coenzyme Q10, particularly to a fermentation process of coenzyme Q10 via flow feeding based on cooperative control of changes of online oxygen consumption rate and conductivity. During the fermentation process of coenzyme Q10 production strains, the oxygen consumption rate is controlled between 30-150 mmol/L·h and the conductivity is maintained between 3.0-30.0 ms/cm via flow feeding, so as to facilitate strain growth and the start of coenzyme Q10 synthesis and accumulation. The present invention can substantially increase output of coenzyme Q10 and greatly reduce the production cost with simple process control and strong operability, thus being applicable to large-scale industrial production.
US10982234B2
Microorganisms that co-consume glucose with non-glucose carbohydrates, such as xylose, and methods of using same. The microorganisms comprise modifications that reduce or ablate the activity of a phosphoenolpyruvate (PEP):carbohydrate phosphotransferase system (PTS) protein or modifications that reduce or ablate the activity of a phosphoglucose isomerase and a GntR. The PTS protein may be selected from an enzyme I (EI), an HPr, an FPr, and an enzyme IIGlc (EIIGlc). Additional modifications include reduction or ablation of the activity of a pyruvate formate lyase, a lactate dehydrogenase, and a fumarate reductase and inclusion of recombinant pyruvate decarboxylase and alcohol dehydrogenase genes. The microorganisms are particularly suited to co-consuming glucose and xylose in media containing these substrates and producing ethanol therefrom.
US10982233B2
A process and system for treating biodegradable waste is described that utilizes serial thermophilic and mesophilic microbial digestion to product fuel gas and a stable solid product at high efficiencies.
US10982230B2
The present disclosure provides a DNA-targeting RNA that comprises a targeting sequence and, together, with a modifying polypeptide, provides for site-specific modification of a target DNA and/or a polypeptide associated with the target DNA. The present disclosure further provides site-specific modifying polypeptides. The present disclosure further provides methods of site-specific modification of a target DNA and/or a polypeptide associated with the target DNA The present disclosure provides methods of modulating transcription of a target nucleic acid in a target cell, generally involving contacting the target nucleic acid with an enzymatically inactive Cas9 polypeptide and a DNA-targeting RNA. Kits and compositions for carrying out the methods are also provided. The present disclosure provides genetically modified cells that produce Cas9; and Cas9 transgenic non-human multicellular organisms.
US10982216B2
A method of generating a cell that enhances functional myelin production is provided, the method including genetically modifying the cell such that: (i) an endogenous PLP1 gene is modified to decrease its ability to inhibit myelin production; (ii) an endogenous PLP1 genetic regulatory element is modified to decrease its ability to promote PLP1 expression; (iii) an endogenous PLP1 genetic regulatory element is modified to increase its ability to inhibit PLP1 expression; or (iv) an endogenous PLP1 gene product or a PLP1 regulatory element gene product that promotes PLP1 expression is modified to decrease the PLP1 expression level, wherein the cell produces functional myelin.
US10982215B2
The invention relates to polynucleotide agents targeting programmed cell death 1 ligand 1 (PD-L1) gene, and methods of using such polynucleotide agents to inhibit expression of PD-L1 and to treat subjects having a PD-L1-associated disorder.
US10982212B2
Conserved consensus sequences from known hepatitis B virus strains and known hepatitis C virus strains, which are useful in inhibiting the expression of the viruses in mammalian cells, are provided. These sequences are useful to silence the genes of HBV and HCV, thereby providing therapeutic utility against HBV and HCV viral infection in humans.
US10982207B2
The invention is a novel method of isolating long nucleic acids from samples suitable for nucleic acid sequencing. The method is especially suitable for isolating low-concentration nucleic acids, e.g., viral nucleic acids, from clinical samples.
US10982202B2
To provide a method for producing a horseshoe crab recombinant Factor C. The horseshoe crab recombinant Factor C is produced through expression thereof by use of mammalian cells such as CHO DG44 and HEK293 as host cells.
US10982189B2
Provided herein are methods for enhancing the transduction efficiency of vectors into cells, e.g., primary human T lymphocytes.
US10982188B2
The invention provides a method of producing a synthetic retina, comprising: i) providing a three dimensional stem cell culture throughout the differentiation time course, ii) differentiating the three dimensional stem cell culture for a first time period in a first neural cell culture medium comprising: a) L-glutamine; b) B27 supplement; and c) an IGF-1 receptor agonist, iii) subsequently differentiating the three dimensional stem cell culture for a second time period in a second neural cell culture medium comprising: a) L-glutamine; b) B27 supplement; c) N2 supplement; and d) an IGF-1 receptor agonist, wherein said synthetic retina contains laminated retinal tissue comprising.
US10982181B2
Devices and systems for cell culture that include one or more hollow fibers or channels integrated into a chamber are provided. The hollow fibers or channels and/or the chamber are seeded with one or more cell types. Methods of co-culturing two or more cell types in the devices are also provided.
US10982179B2
Provided is a dietary fiber characterized in that bitterness and unpleasant aftertaste are restrained. The dietary fiber has terminal sugars and is characterized in that the ratio of aldoses relative to the total of the terminal sugars is 10% or less. Such a dietary fiber may be, for example, indigestible dextrin, polydextrose or the like. The dietary fiber may be used as a food additive (for example, a beverage additive).
US10982174B2
Synergistic surfactant blends are disclosed. In one aspect, the blend comprises an anionic surfactant and a metathesis-based cationic surfactant comprising a quaternized derivative. The quaternized derivative is a quaternized fatty amine, quaternized fatty amidoamine, imidazoline quat, or esteramine quat made from a metathesis-derived C10-C17 monounsaturated acid or its ester derivative. Also disclosed are synergistic surfactant blends comprising a cationic surfactant and a metathesis-based anionic surfactant comprising a sulfonated derivative. The sulfonated derivative is a fatty ester sulfonate, fatty acid sulfonate, sulfoestolide, fatty amide sulfonate, sulfonated fatty ester alkoxylate, imidazoline quat sulfonate, sulfonated amidoamine oxide, or sulfonated amidoamine betaine. The synergistic blends have a negative β value or a reduced interfacial tension (IFT) when compared with an expected IFT value calculated from the individual surfactant components. Blends of the invention also exhibit surprisingly favorable solubility profiles. The surfactant blends are useful for laundry detergents, dish detergents, household or industrial cleaners, personal care products, agricultural products, building materials, oil recovery compositions, emulsion polymers, and other practical applications.
US10982172B2
The present invention relates to novel compounds and their use as fragrance materials.
US10982171B2
The present disclosure provides compositions and methods for enzymatic oil degumming.
US10982169B2
A lubricant composition includes: an oil selected from among polyalkylene glycols (PAG); and a nitrogen compound selected from among amine phosphates or amine tungstates. The lubricant composition is particularly suitable for lubricating a vehicle engine, preferably a motor vehicle engine. Also disclosed is an engine lubrication method utilizing such composition.
US10982167B2
A viscosity index improver comprising a copolymer having a unit (a) derived from a maleimide monomer and a unit (b) derived from a macromonomer, wherein viscosity measured by the following method is 8000 mPa·s or less. Viscosity measurement method: A solution composed of 78 mass % of a Group III base oil (viscosity index: 122, kinematic viscosity at 40° C.: 19.6 mm2/s) on the American Petroleum Institute (API) classification and 22 mass % of the copolymer is measured with a viscometer (TVB-10 manufactured by Toki Sangyo Co., Ltd., rotor: SPINDLE No. M3, rotation speed: 6 rpm) at 25° C.
US10982165B2
Disclosed are materials that possess both low adhesion and the ability to absorb water. The material passively absorbs water from the atmosphere and then expels this water upon impact with debris, to create a self-cleaning layer. The lubrication reduces friction and surface adhesion of the debris (such as an insect), which may then slide off the surface. The invention provides a material comprising a continuous matrix including a polymer having a low surface energy (less than 50 mJ/m2) and a plurality of inclusions, dispersed within the matrix, each comprising a hygroscopic material. The continuous matrix and the inclusions form a lubricating surface layer in the presence of humidity. The material optionally contains porous nanostructures that inject water back onto the surface after an impact, absorbing water under pressure and then releasing water when the pressure is removed. The material may be a coating or a surface, for example.
US10982164B2
A device for starting and maintaining a campfire includes an inner combustible structure formed from a plurality of inner combustible members having bottom end portions separated and secured to a top planar wall of a combustible lower support member. The device further includes an outer combustible structure formed from a plurality of outer combustible members having bottom end portions separated and secured to edge portions of the combustible lower support member. A fire accelerant is disposed in an inner portion of the inner combustible structure to promote a faster starting campfire.
US10982161B2
This invention provides processes and systems for converting biomass into high carbon biogenic reagents that are suitable for a variety of commercial applications. Some embodiments employ pyrolysis in the presence of an inert gas to generate hot pyrolyzed solids, condensable vapors, and non-condensable gases, followed by separation of vapors and gases, and cooling of the hot pyrolyzed solids in the presence of the inert gas. Additives may be introduced during processing or combined with the reagent, or both. The biogenic reagent may include at least 70 wt %, 80 wt %, 90 wt %, 95 wt %, or more total carbon on a dry basis. The biogenic reagent may have an energy content of at least 12,000 Btu/lb, 13,000 Btu/lb, 14,000 Btu/lb, or 14,500 Btu/lb on a dry basis. The biogenic reagent may be formed into fine powders, or structural objects. The structural objects may have a structure and/or strength that derive from the feedstock, heat rate, and additives.
US10982159B2
The present invention relates to a method for reducing the content of monoglycerides (MG), also called monoacylglycerides (MAG), especially of saturated monoglycerides (SMG), in a crude biodiesel (CB).
US10982157B2
The present invention is based on the use of a two-step hydrocracking process for the production of naphtha, comprising a step of hydrogenation placed upstream of the second hydrocracking step, the hydrogenation step treating the unconverted liquid fraction separated in the distillation step in the presence of a specific hydrogenation catalyst. Furthermore, the hydrogenation step and a second hydrocracking step are carried out under specific operating conditions and in particular under temperature conditions that are very specific with respect to one another.
US10982155B2
Asphaltene may be effectively broken into smaller molecules by first elucidating the structure of the asphaltene and then developing a catalyst system based on the elucidated structure. The structure may be determined based on a series of analytical techniques including NMR, FTIR, Raman spectroscopy, XPS, and LDI. The most probable structure is determined using computational methods based on quantum mechanics and classical molecular dynamics and the catalyst system is developed for the most probable structure.
US10982152B2
Methods, processes, systems, or apparatus are provided to remove contaminants such as metals and chlorine present in a pyrolysis stream to form reduced-contaminant liquid biomass. In certain embodiments, for example, a metal chelating agent is dissolved into a metal-containing pyrolysis stream condensate to form metal chelate complex, followed by filtering to obtain the reduced-contaminant liquid biomass.
US10982147B2
The present invention relates to a liquid crystal aligning agent composition for forming a liquid crystal alignment film exhibiting excellent alignment and electrical characteristics and simultaneously having excellent film strength, a method for preparing a liquid crystal alignment film using the same, and a liquid crystal alignment film and a liquid crystal display device using the same.
US10982144B2
Provided are a silicon nitride layer etching composition, and more specifically, a silicon nitride layer etching composition, capable of etching the silicon nitride layer at a high selectivity ratio relative to a silicon oxide layer by comprising a polysilicon compound in the etching composition, an etching method of a silicon nitride layer using the same, and a method of manufacturing a semiconductor device.
US10982136B2
Embodiments relate generally to lanthanide nanocrystals as ultraviolet downconverters.
US10982132B2
Method of fracturing a subterranean formation by injecting an aqueous fracturing fluid comprising an aqueous base fluid, a polysaccharide and/or polysaccharide derivative, a crosslinker, which is a water-soluble, layered silicate and a proppant. Aqueous fracturing fluid comprising an aqueous base fluid, a polysaccharide and/or polysaccharide derivative, a crosslinker, which is a water-soluble, layered silicate and a proppant and to the use of water-soluble, layered silicates as crosslinker for aqueous fracturing fluids comprising polysaccharides and/or polysaccharide derivatives.
US10982131B2
Provided are a phase transition material fluid and a proppant formed therefrom, wherein the components for preparing the phase transition material fluid comprise in percentages by mass: a supramolecular building block 10 to 60 wt %, a supramolecular functional unit 20 to 50 wt %, a dispersant 0.1 to 2 wt %, an inorganic co-builder 0.1 to 1 wt %, an initiator 0.1 to 1 wt %, the balance being a solvent. The supramolecular building block comprises a melamine-based substance and/or a triazine-based substance; the supramolecular functional unit comprises a dicyclopentadiene resin; and the dispersant includes a hydroxyl-bearing polysaccharide substance and a surfactant. After the phase transition material fluid enters the reservoir, it may form a solid substance to prop the fracture under the action of supramolecular chemistry and physics.
US10982130B2
A composition for an environmentally friendly hydrofracturing friction reducer product can be synthesized. A method for synthesis of a friction reducer emulsion can include using gas-to-liquid synthesized oil as a continuous phase in invert emulsion polymerization. The composition can be optimized by using a suitable amount of salt tolerant monomer for the best performance with salt tolerant features. Various inverting agents can be utilized for the self-inverting in brine with good product stability. The optimized friction reducer can be used in weighted brine hydrofracturing.
US10982127B2
A method including introducing a well cementing composition into a wellbore, the cementing composition including a pumpable slurry of cement comprising a liquid anti-shrinkage additive including: an aqueous base fluid; a calcined magnesium oxide; and an anti-hydration agent; and allowing at least a portion of the cementing composition to harden. A liquid anti-shrinkage additive for cement including an aqueous base fluid, a calcined magnesium oxide, and an anti-hydration agent.
US10982124B2
The present application provides a drill-in slurry containing an aqueous base fluid; a solid particulate material; a hygroscopic chelating agent; optionally an alkali formate; and optionally an additional ingredient such as a defoamer, a viscosity modifier, a stabilizer, soda ash or sodium bicarbonate. Methods for making the drill-in slurry and methods of using the drill-in slurry for drilling into a reservoir section or a producing section of a subterranean formation are also provided.
US10982116B2
Adhesives including a polyester at 20 to 50 weight percent, a first tackifier at 30 to 60 weight percent, and a first olefin-styrene block copolymer at 5 to 30 weight percent are described. The polyester has a glass transition temperature between −40° C. and −10° C., and the adhesive has a heat activation temperature between 20° C. and 100° C. Damping films including at least one layer of the adhesive and including a foamed layer are described. The foamed layer includes a second olefin-styrene block copolymer at 30 to 80 weight percent and a second tackifier at 15 to 60 weight percent.
US10982115B2
An adhesive composition according to the present invention contains a polymerizable monomer (A) and a block copolymer (B) including a polymer block (a) which includes structural units derived from a styrene compound and from a maleimide compound, and an acrylic polymer block (b), in which the polymer block (a) and the acrylic polymer block (b) have a solubility parameter of 10.0 or more and 9.0 or more, respectively; the polymer block (a) contains the structural unit derived from a maleimide compound at a concentration from 30% by mass to 99% by mass with respect to the total mass of the polymer block (a); the polymer block (a) has a glass transition temperature of 150° C. or higher; and the polymer block (b) has a glass transition temperature of 20° C. or lower.
US10982114B2
A composition including a carrier comprising a liquid, an abrasive particulate contained in the carrier, an accelerant contained in the carrier, the accelerant including at least one free anion selected from the group of iodide (I−), bromide (Br−), fluoride (F−), sulfate (SO42−), sulfide (S2−), sulfite (SO32−), chloride (Cl−), silicate (SiO44−), phosphate (PO43−), nitrate (NO3−), carbonate (CO32−), perchlorate (ClO4−), or any combination thereof, and a buffer contained in a saturated concentration in the carrier, the buffer including a compound selected from MaFx, NbFx, MaNbFx, MaIx, NbIx, MaNbIx, MaBrx, NbBrx, MaNbBrx, Ma(SO4)x, Nb(SO4)x, MaNb(SO4)x, MaSx, NbSx, MaNbSx, Ma(SiO4)x, Nb(SiO4)x, MaNb(SiO4)x, Ma(PO4)x, Nb(PO4)x, MaNb(PO4)x, Ma(NO3)x, Nb(NO3)x, MaNb(NO3)x, Ma(CO3)x, Nb(CO3)x, MaNb(CO3)x, or any combination, wherein M represents a metal element or metal compound; N represents a non-metal element; and a, b, and x is 1-6.
US10982112B2
A hydrophobic silicone coating composition includes a trialkoxysilane with trialkoxy functionality, a polyfluorinated trialkoxysilane, and an organometallic cure catalyst. A coating on a substrate is provided that includes a cured film produced by the cure of the coating composition. The coating has a contact angle of at least 93 degrees after 500 hours of exposure to UV-A exposure in ASTM D 4329 QUV using UVA 340 bulbs, cycle B exposure of alternate cycles of UV exposure and condensing humidity all at elevated temperature.
US10982111B2
A coating composition comprising a resin material comprising polyester imide polymer one or more titanate material; and one or more OH reactive cross linking material.
US10982107B2
A metal nanoparticle ink composition comprises an ink vehicle and a plurality of metal nanoparticles dispersed in the ink vehicle. The metal nanoparticles including both a first organic stabilizing group and a second organic stabilizing group attached thereto, the first organic stabilizing group being different from the second organic stabilizing group, the first organic stabilizing group being selected from the group consisting of decylamine, undecylamine, dodecylamine, tridecylamine, tetradecylamine and mixtures thereof, and the second organic stabilizing group being selected from group consisting of butylamine, pentylamine, hexylamine, heptylamine, octylamine, nonylamine, decylamine and mixtures thereof.
US10982104B2
To provide an inkjet printing apparatus that improves the smoothness of the ink layer surface and improves the image quality. Provided is an inkjet printing apparatus that prints with a UV curable ink, the inkjet printing apparatus including: an ejection unit configured to eject the UV curable ink onto the surface of a print medium; and a control unit configured to control the ejection of the UV curable ink from the ejection unit, the UV curable ink containing a thixotropy-imparting agent, and the control unit setting the viscosity of the UV curable ink to 1 mPa·s to 20 mPa·s at the time of ejection and to at least 80 mPa·s within five seconds of landing on the print medium.
US10982103B2
The present invention relates to the field of low energy radically curable inks for offset or letterpress printing of security documents. In particular, the invention relates to low energy radically curable offset or letterpress printing inks for offset or letterpress printing on a substrate or security document, said low energy radically curable inks having a viscosity in the range of about 2.5 to about 25 Pa s at 40° C. and 1000 s−1 and comprising radically curable (meth)acrylate compounds, one or more one or more photoinitiators of formula (I), one or machine readable materials and one or more fillers and/or extenders.
US10982100B2
A self-healing, scratch resistant slippery surface that is manufactured by wicking a chemically-inert, high-density liquid coating over a roughened solid surface featuring micro and nanoscale topographies is described. Such a slippery surface shows anti-wetting properties, as well as exhibits significant reduction of adhesion of a broad range of biological materials, including particles in suspension or solution. Specifically, the slippery surfaces can be applied to medical devices and equipment to effectively repel biological materials such as blood, and prevent, reduce, or delay coagulation and surface-mediated clot formation. Moreover, the slippery surfaces can be used to prevent fouling by microorganisms such as bacteria.
US10982098B2
The present invention provides for a method for modifying a covalent organic framework (COF), the method comprising: contacting a COF comprising an imine group with a phenylacetylene in, or to form, a mixture, in a suitable reaction condition for converting the imine group into a quinoline group, and COF comprising a quinoline group. The present invention also provides for a superhydrophobic surface comprising a solid surface coated with or comprising the covalent organic framework (COF).
US10982097B2
A coating system and related methods for an airfield surface or a roadway is described. The coating system may include a stable cationic emulsion for application to the airfield surface or the roadway. The stable cationic emulsion may include a) an asphalt blend comprising gilsonite, wherein the gilsonite is modified to possess a positive charge, b) one or more polymers, and c) one or more surfactants not including a cationic surfactant. The coating system may also include a fine aggregate material for application to the stable cationic emulsion applied to the airfield surface or the roadway.
US10982096B2
Crumb rubber obtained from recycled tires is subjected to an interlinked substitution process. The process utilizes a reactive component that interferes with sulfur bonds. The resulting treated rubber exhibits properties similar to those of the virgin composite rubber structure prior to being granulated, and is suitable for use in fabricating new tires, engineered rubber articles, and asphalt rubber for use in waterproofing and paving applications.
US10982093B2
The present invention provides a low-dielectric resin composition comprising (A) a urethane resin obtained by reacting a polycarbonate diol and an isocyanate, (B) an epoxy resin, and (C) a filler, wherein the (A) urethane resin has a carboxyl group equivalent weight of 1,100 to 5,700 g/eq; the epoxy equivalent weight of the (B) epoxy resin is 0.3 to 4.5 equivalents per 1.0 equivalent of the carboxyl group of the (A) urethane resin, the (A) urethane resin has a weight-average molecular weight of 5,000 to 80,000; the (A) urethane resin has a polycarbonate content of 35% by mass or lower; the resin composition comprises 50 parts by mass or less of the (C) filler per 100 parts by mass of the (A) urethane resin; and the resin composition comprises substantially no imido group.
US10982086B1
The present invention relates to a resin guardrail consisting of a resin composition containing polyvinyl chloride (PVC) and acrylonitrile-butadiene-styrene (ABS) and fixed to a vertical post (P) and, more particularly, relates to a resin guardrail having improved durability and impact resistance, the resin guardrail being produced through extrusion molding of the resin composition containing polyvinyl chloride (PVC) and acrylonitrile-butadiene-styrene (ABS) and made by mixing 1 to 10 parts by weight of microcapsules containing acrylic acid (CH2=CHCOOH), hydrogen peroxide (H2O2), lithium nitrate trihydrate (LiNO33H2O), and acrylonitrile (CH2CHCN), based on 100 parts by weight of resin mixture containing the PVC compound and the ABS compound mixed at a weight ratio of 50:50 to 90:10.
US10982074B2
The invention provides natural rubbers having improved processability and/or abrasion resistance, rubber compositions containing the natural rubbers, and pneumatic tires formed from the rubber compositions. The invention relates to a natural rubber which shows a 1H-NMR spectrum where the sum of peak intensities at about 4.17, 3.94, 3.84, 3.73, 3.50, and 3.41 ppm, normalized to 10,000 for the peak intensity at about 5.11 ppm, is 8.0 or less.
US10982070B2
A crystalline pigment or colorant composition having high color intensity and/or low sugar content, and methods and processes of preparation. The composition may comprise purified fruit and/or vegetable color juices.
US10982069B2
An article comprising a carbon composite containing carbon microstructures having interstitial spaces among the carbon microstructures; and a binder disposed in at least some of the interstitial spaces; wherein the carbon microstructures comprise unfilled voids within the carbon microstructures; and the binder comprises one or more of the following: polytetrafluoroethylene; polyvinyl fluoride; polyvinylidene fluoride; polychlorotrifluoroethylene; perfluoroalkoxy alkane; fluorinated ethylene propylene; ethylene tetrafluoroethylene; ethylene chlorotrifluoroethylene; a peroxide cured copolymer of tetrafluoroethylene and propylene; a fluorocarbon rubber; perfluorocarbon rubber; or a perfluoropolyether.
US10982066B2
Molded polymer foam articles are described as having a novel a foam structure. The polymer foam articles include a continuous polymer matrix defining a plurality of pneumatoceles therein which is present throughout the entirety of the article, including in the surface region extending 500 microns beneath the surface of the article. The surface region is further characterized as having compressed pneumatoceles. The novel foam structure is achieved even when molding polymer foam articles comprising a thickness of more than 2 cm, a volume of more than 1000 cm3; or both a volume of more than 1000 cm3 and a thickness of more than 2 cm. Methods of making the molded polymer foam articles are also described.
US10982065B2
An optical film including: a film base material; and a matte layer formed on one surface of the film base material, wherein the matte layer is formed from a resin composition containing a polyol resin (A), an isocyanate-based curing agent (B) and an antistatic agent having a hydroxyl group (C).
US10982059B2
A fiber-reinforced polymer composition that comprises a polymer matrix that contains a propylene polymer is provided. The polymer matrix constitutes from about 30 wt. % to about 80 wt. % of the composition, and a plurality of long reinforcing fibers that are distributed within the polymer matrix. The fibers constitute from about 20 wt. % to about 70 wt. % of the composition. The polymer composition exhibits a spiral flow length of about 450 millimeters or more as determined in accordance with ASTM D3123-09, and after aging at a temperature of 150° C. for 1,000 hours, a Charpy unnotched impact strength greater than about 15 kJ/m2 as determined at a temperature of 23° C. in accordance with ISO Test No. 179-1:2010.
US10982046B2
Reaction products of an optionally alkoxylated alcohol, a polyalkylene alcohol and a linker can be used in various applications such as defoamers. Methods of making the reaction products and defoamer compositions including the reaction products, and methods of using the reaction products to reduce or prevent foam in a composition are also disclosed. The reaction products can be used with an organic solvent or without an organic solvent to provide low VOC compositions.
US10982031B2
The present invention is related to the application of terpolymers based on alkyl acrylates as defoamers of gasified crude oils, with densities between 10 and 40° API. The evaluation of terpolymers based on alkyl acrylates at conditions similar to those of gas-liquid separators has shown that the terpolymers are efficient as inhibitors of the foam formation in heavy and super-heavy crude oil, abating the foam between 15 and 50% faster than in non-dosed crude oil (blank). Even some acrylic terpolymers exhibited a greater efficiency as defoamers than that of commercial silicon-based polymers, which promoting the defoaming only 20-25% faster than the blank collapse. The employ of silicones as defoamers presents serious problems as the formation of deposits and the deactivation of catalysts in the refining processes. This situation has provoked that refineries in Mexico and a worldwide ban the application of this kind of inorganic polymers, and new silicon-free defoaming agents are required. Therefore, the new silicon free defoamers object of this invention represent an advantageous option to replace the silicon based defoamers employed nowadays by the petroleum industry.
US10982029B2
Provided are an acrylic rubber composition having higher tensile properties and higher heat resistance and a vulcanizate thereof. An acrylic rubber composition includes 1 to 25 parts by mass of a layered clay mineral relative to 100 parts by mass of an acrylic rubber. The acrylic rubber is a copolymer of a (meth)acrylic acid alkyl ester and a curesite monomer.
US10982023B2
Catalyst support-activator for olefin polymerization catalysts, and processes for making, the support-activator comprising an intercalated, modified and calcined smectite clay comprising (a) pillars comprising aluminum and optionally: (i) at least one rare earth or lanthanide group metal; or (ii) at least one rare earth or lanthanide group metal and gallium; and (b) at least one ion-exchanged metal ion selected from the group consisting of aluminum, barium, beryllium, calcium, cerium, cesium, copper, chromium, gadolinium, gallium, germanium, hafnium, holmium, iron (II and III), lanthanum, lithium, magnesium, manganese, neodymium, potassium, praseodymium, rubidium, samarium, silver, selenium, sodium, strontium, tellurium, terbium, thallium, thorium, tin, titanium, uranium, ytterbium, yttrium, zinc and zirconium. The pillared clay exhibits a basal d100 spacing of: (A) 9 to 18 angstroms; or (B) equal to or greater than about 18.5 angstroms. Use of the modified clays, with metallocene catalyst precursor components, provides active olefin polymerization catalysts, preferably in the substantial absence of aluminoxanes or boron-containing compounds.
US10982021B2
A flame retardant with which fire retardancy is improved and the fire retardancy is able to be secured stably for a long time is provided. An internal layer 11 containing a polymer and a flame retardant factor layer 12 that is formed outside of the internal layer 11 and that contains a polymer to which at least one of a sulfonate group and a sulfonate base is bonded are included. Thereby, compared to a case that the flame retardant factor layer 12 is not included, moisture is hardly absorbed, and respective particles of the flame retardant are inhibited from being adhered to each other. Accordingly, blocking is inhibited.
US10982020B2
There is provided a resin-treated pigment that is useful as a coloring agent for color filters or inkjet inks, that can expand a hue range and improve performances such as color density, color developability, and transparency, and that is excellent in properties such as dispersibility and dispersion stability of pigments, re-dissolvability, and alkali-solubility. An A-B block copolymer 90% by mass or more of which is constituted by a methacrylate-based monomer or methacrylate-based monomers, in which the block A has a carboxy group-containing methacrylate as a constituent, and the block B has an ionic bond moiety represented by formula (1) as a constitutional unit, the ionic bond moiety containing a methacrylate, and an organic coloring matter having one or more sulfonate ions each being bonded thereto and each being a counter ion of a nitrogen cation of a quaternary ammonium salt.
US10982017B2
A process of manufacturing a polyolefin drag reducing agent comprises: injecting a catalyst and a drag reducing agent forming component comprising (i) at least one olefin monomer, or (ii) at least one olefin oligomer, or a combination of (i) and (ii) into a temporary container comprising a container material, sealing the temporary container; allowing the drag reducing agent forming component to polymerize in the sealed temporary container to form the polyolefin drag reducing agent; and at least partially dissolving the container material. The container material includes an ethylene vinyl acetate copolymer, an ethylene vinyl alcohol copolymer, a polyvinylpyrrolidone, an ethylene vinylpyrrolidone copolymer, a vinylpyrrolidone vinyl acetate copolymer, a polyvinyl acetate, a polyvinyl alcohol, a polyethylene glycol, a polysaccharide or its derivative, or a combination comprising at least one of the foregoing, provided that when the container material comprises polyvinyl acetate or polyvinyl alcohol, the temporary container is coated or has two or more layers.
US10982012B2
A process for dissolving modified cellulose is disclosed. The process includes contacting modified cellulose with a solvent in a mixture to form swelled modified cellulose and then contacting the mixture with a salt to dissolve the swelled modified cellulose.
US10982007B2
A bivalent binding agent having a first monovalent binder that binds to a polypeptide epitope of a target polypeptide, a second monovalent binder that binds to a posttranslational polypeptide modification on the target polypeptide and a linker. Further disclosed are methods for the detection of a posttranslationally modified target polypeptide, for making the disclosed bivalent binding agent, and for use of the disclosed bivalent binding agent in histological staining procedures.
US10981992B2
The present invention is directed to bispecific, heterodimeric immunomodulatory antibodies.
US10981975B2
The present invention describes a simple purification process for recombinant human serum albumin. The process results in highly purified protein with limited number of purification steps. The broth containing human albumin is clarified by centrifugation and microfiltration, diafiltered and captured by cation exchange chromatography by a process that allows 140-230 mg of albumin to be captured per ml of resin. Product related impurities are removed by hydrophobic interaction chromatography, optimised to allow 87-97% recovery in flow through mode. The final series of processes are so combined that there is easy transition from one step to the next with minimal interventions and adjustments. The entire process of purification is completed within two days from harvest to final product. Thus a cost-effective process with improved recovery of protein at each step is developed. The purified human serum albumin is analyzed for purity and shows physicochemical characteristics that are similar to standard albumin.
US10981969B2
The present invention relates generally to a fusion protein that when displayed on a cell can convert a negative signal into a positive signal in the cell. The fusion protein is a chimeric protein in that the protein comprises at least two domains, wherein the first domain is a polypeptide that is associated with a negative signal and the second domain is a polypeptide that is associated with a positive signal. Thus, the invention encompasses switch receptors that are able to switch negative signals to positive signals for enhancement of an immune response.
US10981966B2
The application relates to compositions or formulations comprising variant IL-10 molecules, fusion proteins, and chimeric proteins thereof useful for the treatment of cancer, inflammatory diseases or disorders, and autoimmune diseases or disorders.
US10981963B2
This invention relates to an alpha-1-microglobulin derived protein for medical use.
US10981959B2
Compositions comprising a mixture of proteins derived from MaSP, nucleic acids encoding same and method for the preparation of synthetic dragline spider silk are provided. The compositions of the invention comprise a mixture of proteins of differing molecular weight, wherein each protein of said mixture comprises, independently, multiple repeats of a repetitive region of a MaSP (major ampullate spidroin) protein or a functional homolog, variant, derivative or fragment thereof.
US10981953B2
A method for promoting expression of calreticulin in at least one kind of eukaryotic cell, and a synthetic peptide useful in this method are provided. In the method provided by the present invention, a culture of target cells is prepared, and a calreticulin expression-promoting peptide having calreticulin expression-promoting activity is supplied at least once to that culture.
US10981952B2
The present invention regards specific IBAT inhibitors useful in the prophylaxis and/or treatment of a liver disease. It also relates to compositions comprising these IBAT inhibitors, a method for treatment of the disorders and a kit comprising the substances or the compositions.
US10981947B2
The invention relates to a container holder 10, comprising a main body 12 which in turn comprises a gas inlet 16; a solution liquid outlet 18; a gas control valve 20 through which a gas enters the container 100 from the gas inlet; and a sealing means 22 for the container, which sealing means includes a passageway 24 for the input of gas and output of a solution in the container via an egress tube 19; wherein when the container is connected to the container holder through the sealing means, the gas control valve opens automatically, and when the container is disconnected the gas control valve is closed automatically. The invention further relates to a container panel 50 which includes two or more container holders. Also disclosed are methods of using these containers and container panels for synthesizing a polypeptide.
US10981944B2
Compounds that modulate the conversion of AMP to adenosine by 5′-nucleotidase, ecto, and compositions containing the compounds and methods for synthesizing the compounds, are described herein. The use of such compounds and compositions for the treatment and/or prevention of a diverse array of diseases, disorders and conditions, including cancer- and immune-related disorders, that are mediated by 5′-nucleotidase, ecto is also provided.
US10981943B2
Antimicrobial compounds and compositions of Formula (I) and methods of use are disclosed.
US10981940B2
The invention is to develop a protecting group that does not solidify or insolubilize a compound in which a functional group has been protected, and facilitates separation and purification after a reaction. Disclosed is a trityl compound represented by General Formula (1): wherein Y represents a hydroxy group or a halogen atom; at least one of R1 to R15 represents a group represented by Formula (2): —O—R16—X-A (2) while the other groups each represent a hydrogen atom, a halogen atom, an alkyl group having 1 to 4 carbon atoms, or an alkoxy group having 1 to 4 carbon atoms; R16 represents a linear or branched alkylene group having 1 to 16 carbon atoms; X represents O or CONR17 (here, R17 represents a hydrogen atom or an alkyl group having 1 to 4 carbon atoms); and A represents a group represented by, for example, Formula (3): wherein R18, R19, and R20, which may be identical or different, each represent a linear or branched alkyl group having 1 to 6 carbon atoms, or an aryl group which may have a substituent.
US10981938B2
Disclosed are polycyclic aromatic compounds that can be employed in various organic layers of organic electroluminescent devices. Also disclosed are organic electroluminescent devices including the polycyclic aromatic compounds. The organic electroluminescent devices are highly efficient and long lasting and have greatly improved luminous efficiency.
US10981936B2
Oligomeric compounds useful as organic conjugated materials in electronic devices. Oligomeric compounds contain three or more or four or more of certain PDI units bonded to an organic core. The organic core contains one, two or more thiophene rings. The organic core can contain two or more thiophene rings separated by a linker group; two or more thiophene rings directly fused to each other or indirectly fused to each other through an optionally substituted aromatic or non-aromatic carbocylic ring system or an optionally substituted aromatic heterocyclic or non-aromatic heterocyclic ring system; or each of two or more thiophene rings is fused to an aromatic or non-aromatic carbocylic ring system or an aromatic heterocyclic or non-aromatic heterocyclic ring system and the resulting fused rings containing a thiophene ring are each separated by a linker group M. Methods for making oligomeric compounds by direct heteroarylation are provided.
US10981909B2
Provided herein is a synthetic process for preparing a compound of Formula (1). The disclosure also provides useful intermediates and salts, amorphous and polymorph forms of the compound of Formula (1). These compounds are useful for various disease including cancer, abnormal cellular proliferation, angiogenesis, Alzheimer's disease, and osteoarthritis as well as Wnt-related diseases.
US10981906B2
The present invention relates to new pyrrolopyridine compounds and compositions and their application as pharmaceuticals for the treatment of disease. Methods of inhibition of JAK1 and JAK3 kinase activity in a human or animal subject are also provided for the treatment diseases such as pruritus, alopecia, androgenetic alopecia, alopecia areata, vitiligo and psoriasis.
US10981902B2
The present invention is directed to 5-(pyridine-3-yl)oxaxole compounds which are allosteric modulators of the M4 muscarinic acetylcholine receptor. The present invention is also directed to uses of the compounds described herein in the potential treatment or prevention of neurological and psychiatric disorders and diseases in which M4 muscarinic acetylcholine receptors are involved. The present invention is also directed to compositions comprising these compounds. The present invention is also directed to uses of these compositions in the potential prevention or treatment of such diseases in which M4 muscarinic acetylcholine receptors are involved.
US10981901B1
Disclosed are compounds having the formula: wherein q, r, s, A, B, C, RA1, RA2, RB1, RB2, RC1, RC2, R3, R4, R5, R6, R14, R15, R16, and R17, are as defined herein, or a tautomer thereof, or a salt, particularly a pharmaceutically acceptable salt, thereof.
US10981899B2
Provided are 6-amino substituted 2,6-diamino-4-chloropyrimidine compounds which are specific inhibitors of soluble adenylyl cyclase. The compounds can be formulated with pharmaceutical carriers and used for reducing cyclic AMP levels. The compositions can be used for treatment of various conditions including ocular hypotony.
US10981895B2
The present invention relates to crystalline forms of (1aS,5aS)-2-(4-oxy-pyrazin-2-yl)-1a,2,5,5a-tetrahydro-1H-2,3-diaza-cyclopropa[a]pentalene-4-carboxylic acid ((S)-1-hydroxymethyl-2,2-dimethyl-propyl)-amide (Compound 1) and pharmaceutical compositions thereof that modulate the activity of the cannabinoid CB2 receptor and are therefore useful in the treatment of CB2 receptor-mediated disorders, for example, osteoarthritis; pain; hyperalgesia; allodynia; inflammatory hyperalgesia; neuropathic hyperalgesia; acute nociception; osteoporosis; multiple sclerosis-associated spasticity; autoimmune disorders; allergic reactions; CNS inflammation for example; atherosclerosis; undesired immune cell activity, and inflammation associated with a disorder selected from: osteoarthritis, anaphylaxis, Behcet's disease, graft rejection, vasculitis, gout, spondylitis, viral disease, bacterial disease, lupus, inflammatory bowel disease, autoimmune hepatitis, and type 1 diabetes mellitus; age-related macular degeneration; cough; leukemia; lymphoma; CNS tumors; prostate cancer; Alzheimer's disease; stroke-induced damage; dementia; amyotrophic lateral sclerosis; and Parkinson's disease.
US10981890B2
The invention discloses compounds of Formula (I), wherein A1, R1, R2, R3, R4, and n are as defined herein. The present invention relates to compounds and their use in the treatment of cystic fibrosis, methods for their production, pharmaceutical compositions comprising the same, and methods of treating cystic fibrosis by administering a compound of the invention.
US10981888B2
Methods for preparing compounds of formula (I) Wherein R1 to R5 and A1 to A4 are as defined in the application.
US10981882B1
A compound for inhibiting IDO represented by the following general formula I, wherein a bond represented by a wavy line “” indicates the structure which represents independently a cis-isomer, a trans-isomer, or a mixture of cis- and trans-isomers; R1 and R2 are each independently selected from the group consisting of H, halogen, alkyl, alkoxyl, and haloalkyl; R3 is selected from the group consisting of cyclopentyl, cyclohexyl, piperazinyl, and piperidyl; and the substitution positions of R3 are optionally substituted at 1,2 position, 1,3 position or 1,4 position; m and n are an integer number independently selected from 0 to 5. The compound has a strong inhibiting effect on IDO and can be used to manufacture an IDO inhibitor for the prevention and/or treatment of an IDO-mediated disease with the pathologic features of the tryptophan metabolic pathway.
US10981881B2
The present disclosure relates generally to compounds which bind to the NR1H4 receptor (FXR) and act as agonists of FXR. The disclosure further relates to the use of the compounds for the preparation of a medicament for the treatment of diseases and/or conditions through binding of said nuclear receptor by said compounds and to a process for the synthesis of said compounds.
US10981879B2
The present invention provides compounds of Formula (I): wherein A, X and Y are as defined in the specification, and compositions comprising any of such novel compounds. These compounds are myeloperoxidase (MPO) inhibitors and/or eosinophil peroxidase (EPX) inhibitors, which may be used as medicaments.
US10981876B2
The present specification provides a spiro structured compound represented by the following Chemical Formula 1 and an organic light emitting device including the same: wherein L1, n, Ar1, R1 to R7, p, q, r, s, and t are defined herein.
US10981874B2
The present disclosure relates to the use of a compound of formula (I) or anyone of its pharmaceutically acceptable salts, in the treatment and/or prevention of an inflammatory disease; wherein: means an aromatic ring wherein V is C or N and when V is N; Q is N or O, provided that R″ does not exist when Q is O; R′ independently represent a hydrogen atom or a group chosen among a (C1-C3)alkyl group, a halogen atom, a hydroxyl group, a —COOR1 group, a —NO2 group, a —NR1R2 group, a morpholinyl or a morpholino group, a N-methylpiperazinyl group, a (C1-C3)fluoroalkyl group, a —O—P(═O)—(OR3)(OR4) group, a (C1-C4)alkoxy group and a —CN group, and can further be a group chosen among:
US10981869B2
The invention provides bridged diindole compounds, related pharmaceutical compositions and methods of use thereof, for the prevention, palliation and/or treatment of nervous system disorders.
US10981861B1
The present disclosure provides a bromination method for m-diamide compounds comprising reacting a compound represented by formula I with a brominating reagent in the presence of an oxidant to obtain a brominated product represented by formula II. The method adopts a special design of brominating reagents and reaction conditions to introduce a bromine atom at a specific site of the m-diamide compound, with 87.9 to 99.5% yield of a brominated product obtained by the reaction and higher than 91.8% purity. Therefore, the bromination method has a simple route, mild reaction conditions, high efficiency, and does not require complicated and cumbersome post-treatment processes; furthermore, raw materials used for the bromination reaction are readily available, costs of the brominating reagent are low, and the brominated product finally obtained has high yield and high purity, thus the method is a novel one with a broad application prospect.
US10981848B2
A carbon dioxide electrolytic device includes: an electrolysis cell including a cathode, an anode, cathode and anode flow paths, and a separator; a carbon dioxide source to supply carbon dioxide to the cathode flow path; a solution source to supply an electrolytic solution containing water to the anode flow path; at least one sensor to acquire at least one data of a data indicating a discharge amount per unit time of a liquid containing water to be discharged from at least one flow path and a data indicating a concentration of at least one ion in the liquid; a refresh material source including a gas source to supply a gaseous substance to the at least one flow path; and a controller programmed to stop the supply of the carbon dioxide and the electrolytic solution, and start supply of a gaseous substance from the refresh material source, in accordance with the at least one data.
US10981842B2
A fertilizer product comprising an acid-carbonized microporous matrix derived from expanded biomass and a fertilizer reaction product of residual acid from the carbonizing process and at least one added fertilizer precursor. The biomass may include steam exploded wood powder. The expanded biomass may be carbonized with a combination of sulphuric and phosphoric acids, followed by ammoniation to produce ammonium sulphate and mono- or diammonium phosphate. The fertilizer reaction product adsorbs onto the carbon matrix, which results in a slow-release when the material is applied to the soil.
US10981841B1
A stabilized ammonium humate mixture including an amount of humic acid between about 7.0% to about 10% of the mixture and an amount of ammonia between about 1.0% to about 14% of the mixture, where the remainder of the mixture is water. The stabilized ammonium humate mixture has a pH between about 9 to about 11.
US10981834B2
A composite material containing carbon and a plastic includes: a) provision of a pulverulent composition with one or more components of amorphous carbon, graphite and mixed forms thereof, b) provision of a liquid binder, c) planar deposition of a layer consisting of the material provided in step a) and local deposition of droplets of material provided in step b) onto this layer and any number of repetitions of step c), the local deposition of the droplets in the successive repetitions of this step being adapted according to the desired shape of the component to be produced, d) at least partial curing or drying of the binder to obtain a green body that has the desired shape of the component, e) impregnation of the green body with a liquid synthetic resin and f) curing of the synthetic resin to produce a synthetic resin matrix.
US10981817B2
A technique for wastewater treatment involves ensuring that all paths for wastewater must pass through at least one porous microbial support to go from the inlet to the outlet, and allowing a biofilm to grow on the porous microbial support under microaerobic conditions (concentration of oxygen between 0.05 and 0.35 mg/L). The biofilm formed comprises a population of anaerobic microbes for digesting organics in the wastewater including methanogenic microbes, and an aerobic methanotrophic and heterotrophic population that catabolizes methane from the methanogenic microbes, and oxygen from the injector, to produce heat. The support may be an electrode, and the technique is applied in a microbial electrolysis cell, with substantial COD removal rates.
US10981815B1
A manufacturing process for a one piece tank that involves three steps results in a consistently watertight and structurally stronger unit than previous tanks. The three steps comprise a process for producing the body of the tank, a process for producing a preliminary lid, and a process for producing the final tank. An important step in the process for producing the body of the tank is extending reinforcing steel (rebar) a distance above the concrete walls of the tank. After the preliminary lid is placed into a groove of the tank, the rebar is bent over the lid and a water stop is applied between the walls of the tank and the preliminary lid. The water stop can be any of several forms. In one form, the water stop is in the form of butyl or rubber strip which projects from the walls of the tank above the walls with the rebar. In an alternate form, the water stop is in the form of a gasket of plastic or other suitable material inserted in a groove at the top of the tank. Once the preliminary lid is in place and the rebar bent over the preliminary lid, reinforcing steel (rebar) is bent over the preliminary lid and secured to proper locations. Then concrete is poured to the top and above the sidewalls of the tank until completely full. The resulting cured structure is a one piece water tight tank with an integral water stop.
US10981811B2
A wastewater treatment system and method for remediating wastewater and human waste that is self-contained and that has no connection to a municipal wastewater system and no connection to an electrical grid. The domestic toilet and wastewater treatment system can be powered by a photovoltaic panel as a source of electricity. The system includes an electrochemical cell that allows a waste stream to be disinfected in a few hours to a condition where no viable bacterial colonies can be cultured. The system produces a liquid stream that is suitable for system flushing or for uses in which non-potable water is acceptable. The system can generate hydrogen as a product that can be used to generate power. The system can generate nitrate, urea, ammonia and phosphate for use as fertilizer. The disinfected residual organic solids are also completely disinfected for potential use as an organic soil amendment for agriculture.
US10981793B2
A method for extracting metal ions from water is provided that includes disposing two electrically conductive electrodes in water, where the water includes a target ion species in solution, where at least one of the electrically conductive electrodes is a functionalized electrode having species-specific adsorption of the target ion species, and providing electrical current to the electrically conductive electrodes such that the one or more target ion species are deposited to metallic form or metal oxides at the functionalized electrode by one or more electrochemical reactions.
US10981789B2
The present invention provides a method for further uniformly drawing out a carbon nanotube web while inhibiting mixing of edge scraps. A carbon nanotube web is drawn out from a carbon nanotube array-in a state in which abutting members which abut on the carbon nanotube array are provided on respective outer sides of both edges of a boundary region between the carbon nanotube array and the carbon nanotube web.
US10981787B2
An oxygen generator includes a bag body and supporting components. The bag body is configured to contain a reactive liquid, a reactant and a catalyst, and the bag body includes a bag piece, a circumferential sealing part and separation parts. The circumferential sealing part is bound with a part of the periphery of the bag piece, so as to define a range of an inner space, and a range of the rest part of the periphery of the bag piece defines an opening. Both ends of each separation part are connected to the circumferential sealing part so as to separate the inner space into a plurality of separate spaces, and the plurality of separate spaces respectively contain the reactant and the catalyst. The supporting components are contained in one of the plurality of separate spaces, and the positions, corresponding to the supporting components, of the bag body are incompressible.
US10981776B2
An apparatus for upholstering a truss allows an operator to staple a fabric web to the truss, rotate the truss, further staple the semi-finished truss and cut the fabric web. The truss is fully upholstered after the end surfaces of the truss are wrapped up in fabric and the fabric stapled in place. The apparatus may accommodate different size trusses. A web of fabric is pulled around at least one roller in the apparatus by rotation of two vise mechanisms on opposite sides of the truss.
US10981767B1
An edge-breaking can opener includes a first clamping handle and a second clamping handle. The first clamping handle and the second clamping handle are rotatably connected by using a rivet. A round angle is set between a tray gear and a helical gear, which reduces a cutting height. A protrusion portion on an original cutter wheel is creatively changed to an elastically adjustable support wheel that acts on a can with different edge heights. It is convenient to perform occlusion during cutting, and a cut can cover can be directly and safely taken out, thereby preventing a hand from coming into contact with the can cover. The cutter wheel can easily perform cutting by using acting force of spring plate, which is suitable for cans with a certain material thickness.
US10981765B2
A pipe coil lifting device includes a superstructure with a central longitudinal member and at least two supports attached to opposite sides of the central longitudinal member, with two channels at the outside long-edges of the superstructure attached to the supports, with a convex upper surface attached to the supports of the superstructure.
US10981761B2
An apparatus for lifting and transporting loads, in particular corresponding containers, preferably in the form of empty containers, including a support chassis, for resting and movement means of the apparatus with respect to the ground, in particular including means, or front wheels, for resting and movement and means, or rear wheels, for resting and movement, in particular said front and/or rear means, or wheels, for resting and movement having a respective transversal, or horizontal, rotation axis; lifting and lowering means of the load, including a respective mast, in particular extending upwards, and gripping means of the load, which gripping means are mobile along said mast; said mast of said lifting and lowering means of the load being positioned at or posteriorly of the respective rotation axis of the front means, or wheels, for resting and movement of the apparatus with respect to the ground.
US10981760B2
A centrifugal brake mechanism for a controlled descent device, and a drum device employing it. The brake mechanism comprises a circular wheel configured and operable to rotate about an axis of rotation, an axle extending along and rotatable about the axis inside a central cavity of the wheel and having two or more parallel shaft rods extending inside the cavity substantially perpendicular to the axis of rotation, a gear system for transferring rotations of the wheel into counter-rotations of the axle, one or more brake elements each having two or more pass-through bores for slidably mounting over the two or more parallel shaft rods, two or more springs mounted over the parallel shaft rods between the brake element and the axle, and a friction enhancement mechanism for increasing friction forces between the brake elements and the inner wall the wheel responsive to increase in angular velocity of the wheel.
US10981755B2
Monitoring device (30) for monitoring a drive element (12) of a conveyor (1), in which the drive element (12) extends in a conveyance direction. The monitoring device (30) comprises a mechanism (39) attached to the drive element (12) and configured for mechanically monitoring a distance between two predetermined locations of the drive element (12) spaced apart in the conveyance direction. The monitoring device (30) is further configured for triggering an alarm signal in case the monitored distance exceeds a predetermined limit.
US10981746B2
A coating film transfer tool may include a casing that houses a feeding reel around which a transferable tape is wound and a winding reel; and a transfer head having a main body portion arranged in a front side which is one side of a front-rear direction of the casing to extend in a left-right direction perpendicular to the front-rear direction in a front end portion and provided with a pressing edge portion adapted for transferring the coating film to a transfer target surface. The casing or a base member housed in the casing may have a protruding tip that extends to the transfer head side and is connected to the transfer head. The protruding tip may press a part of an area including a center of the left-right direction of the main body portion to the transfer target surface side in the event of a transfer.
US10981734B2
A conduit access includes a base plate, a sensor, a motor, and a pivoting door plate. The base plate includes a pivot joint, a pass-through, and a stop. The pivot joint is at an edge of the base plate and extends toward a backside of the base plate. The pass-through is in a center of the base plate. The stop is on a rim of the base plate. The stop has a raised thickness on a frontside of the base plate. The sensor is in the pivot joint to detect motion. The motor is coupled to the pivot joint on the backside of the base plate. The motor activates on detection at the sensor. The pivoting door plate is parallel to the base plate. The pivoting door plate is coupled to the motor through the pivot joint to pivot across the frontside of the base plate to cover the pass-through.
US10981733B2
A product sorting apparatus includes a pallet station supporting a pallet on which a product is placed and moves up and down between a base position and a raised position, a transfer device transferring the product to a first area that is on a first side of the pallet station, a first cart movable between the first area and a second area that is on a second side of the pallet station, and a second cart movable between the first area and the second area and able to pass through the inside of the first cart. Through the inside of the pallet station set at the base position, the first cart is unable to pass and the second cart is able to pass, and through the inside of the pallet station set at the raised position, both the first and second carts are able to pass.
US10981732B2
A device for reliably sweeping or sorting an article from a main conveyor surface that is positioned above the main conveyor surface and includes a paddle assembly that can be adjusted for moving various different articles from the main conveyor.
US10981726B2
An appliance-support system in accordance with the present disclosure includes a truss and a positioning system coupled to the truss. The positioning system is adapted to support an appliance, such as a video display, light, speaker, or other device used during stage performances or events.
US10981723B2
An inventory handling system includes multiple shelving units for mounting over a horizontal floor. Each shelving unit contains a vertical array of shelves on which containers are placed. One or more floor robots travel among the shelving units along first paths on the floor. One or more lift robots move independently of the floor robots along second paths in a vertical plane over vertical faces of the shelving units, and transfer the containers between the shelves and the floor robots.
US10981717B2
A packaging product for packaging flat products (e.g., flat stock) such as abrasive articles, e.g., abrasive disks. The packaging product is designed to display flat stock products while maintaining the geometric properties and integrity of the products. The packaging product has a first component that is an engagement member, a second component that is a first retention portion and a third component that is a second retention portion. The engagement member engages with the first and second retention portions to secure a plurality of products between the retention portions.
US10981716B2
An insulating device can include an aperture having a waterproof closure which allows access to the chamber within the insulating device. The closure can help prevent any fluid leakage into and out of the insulating device if the insulating device is overturned or in any configuration other than upright. The closure may also prevent any fluid from permeating into the chamber if the insulating device is exposed to precipitation, other fluid, or submersed under water. This construction results in an insulating chamber that is substantially impervious to water and other liquids when the closure is sealed.
US10981714B2
A thermal conditioning wall panel 10 for use in a thermally insulating container comprises a panel body (22) having a channel (26) formed therein along one face thereof for receiving one or more thermal conditioning elements (12). At least one foot (32) is formed at the lower end of the body (22) for engagement within a socket provided on the thermally insulating container. The panel further comprises thermal conditioning element retaining elements (40) provided adjacent the longitudinal edges (29) of the channel (26), the retaining elements (40) projecting over a peripheral portion of the channel (26) for retaining the thermal conditioning elements (12) within the channel (26).
US10981712B2
A protective product, such as, e.g., an envelope or pouch, is provided that includes at least one expanded slit paper sheet in an expanded state, and an embossed paper sheet facing the expanded slit paper sheet and fixed to the expanded slit paper sheet along at least a portion of a length in an expansion direction of the expanded slit sheet paper. In the preferred embodiments, the embossed paper sheet has a plurality of embossings that increase the rigidity of the embossed paper sheet, thereby inhibiting deformation of the embossed paper sheet that is fixed to the expanded slit sheet paper.
US10981708B2
Methods of making packages from flexible material, wherein the packages include one or more self-folds formed by applying activation energy to the flexible material.
US10981705B2
A dual port dispenser button system which has an elastic receptacle button that includes a first latch receiver and a second latch receiver. The system includes a dispenser with a first dispensing port and a second dispensing port. The system includes a first valve including a first valve seal member and a first button latch and a second valve including a second valve seal member and a second button latch. When the button is depressed, the first valve seal member moves from a first position in which it seals the first dispensing port to a second position in which it does not seal the first dispensing port and the second valve seal member moves from a second position in which it seals the second dispensing port to a second position in which it does not seal the second dispensing port.
US10981704B2
A pressurised headspace beverage closure 1 that may be opened and reclosed in at least substantially a one-handed manner; comprising a drinking aperture, at least one headspace pressure lock mechanism 5, at least one controlled-rate headspace pressure equalisation valve arrangement 6 and a sealing system 7 suitable for multiple re-use, and whereby when the headspace pressure 10 is at least substantially above or below atmospheric pressure the headspace pressure lock mechanism 5 may employ the use of the headspace pressure 10 itself to ensure that the closure cannot freely be opened by a user, whereby the headspace pressure equalisation valve arrangement 6 may freely enable the headspace pressure 10 to be vented such that it may at least substantially equalise with atmospheric pressure at a pre-set and controlled rate preferably independent of a user thereby allowing safe and controlled venting of the headspace pressure 10, and whereby once the headspace pressure 10 has at least substantially equalised with atmospheric pressure the headspace pressure interlock system 5 may release its headspace pressure lock sufficiently to enable the one-handed closure to be fully and freely opened and reclosed as required.
US10981697B1
A stackable spray bottle assembly includes a top stackable spray bottle and a bottom stackable spray bottle detachably engaged therewith. Each of the top stackable spray bottle and the bottom stackable spray bottle include a reservoir having an open top portion and a closed bottom portion, and an accessory removably coupled to the open top portion. Advantageously, the accessory has a first silhouette, and the bottom portion has a second silhouette conforming to the first silhouette such that, during storage, the top stackable spray bottle is maintained at a substantially stable position when stacked on top of the bottom stackable spray bottle.
US10981696B2
The present disclosure concerns a coupling mechanism for detachably attaching two or more utility modules to one another, utility assembles, mobile carriers and other attachable modules and articles.
US10981694B2
A metallic container end closure is provided that generally comprises a dispensing opening and a vent opening. The vent opening improves pourability through the dispensing opening and provides an alternative option for consuming the contents of the container. The end closure may include features to ease opening of the vent opening, such as stiffeners and/or vent form features.
US10981691B2
A telescoping insulated box assembly, comprising: an outer box, the outer box comprising a side wall and a bottom wall, the side wall and the bottom wall of the outer box each defining an insulation cavity; and an inner box, the inner box comprising a side wall and a wall forming a portion of a top side of the box assembly, each wall of the inner box defining an insulation cavity, the inner box sized to fit into the outer box such that the each of the side walls of the inner box faces one of the side walls of the outer box.
US10981688B2
A packaging assembly including a sealing station for sealing a product with at least one film web, wherein a printer is provided upstream of the sealing station and configured to print information, in particular a product weight and an associated retail price, onto the film web or onto a label, which may already be present on the film web, wherein, upstream of the sealing station, a forward weighing device is provided and configured to detect a weight value of a product and forward it to a control unit. The packaging assembly is characterized in that the control unit controls the printer for printing-on the information depending on the detected weight value, and that, downstream of the sealing station, at least a first inspection device is provided to read the information on the imprint. A method for making the packaging assembly is also included.
US10981686B2
A machine for winding suture into a suture tray package includes a base platform with package nests, each nest including upwardly-extending locating pins. A workstation places an empty tray onto one nest. Another workstation feeds a needle with attached suture in the tray and parks the needle in the tray. A winding station for winding the suture into a tray winding channel includes a rotatable winding head with configurable suture guiding pins, a stripper plate pushing the wound suture off the guiding pins, a suture control arm with proximal and distal ends and top and bottom sides, the distal end having a front standoff and a rear standoff incorporating a suture guiding channel, and a base member mounting the arm to base platform. A lid placement station places a lid onto a nest, a lid attachment station attaches lid to tray and an offloading station removes trays from nests.
US10981679B2
A satellite dispenser door release mechanism is disclosed. In various embodiments, a satellite door dispenser as disclosed herein includes a wire or cable having a first end configured to be secured in a structure comprising or coupled to a dispenser body of a satellite dispenser and a second end configured to be secured in a structure comprising or coupled to a dispenser door of the satellite dispenser; and a pyrotechnic cutter configured to receive the wire or cable in a position to cut the wire or cable upon firing of the pyrotechnic cutter.
US10981673B2
A bond fixture includes a support structure and a first assembly coupled to the support structure. The first assembly includes a frame defining a chamber and a first pressure pad and second pressure pad coupled to the frame opposite one another and positioned within the chamber. The second pressure pad is movable to control a pressure applied by the first pressure pad and the second pressure pad.
US10981662B2
The present disclosure is directed to a method for determining an aircraft minimum low pitch setting for a propeller assembly and minimum gas generator idle speed for a gas generator, in which the propeller assembly and the gas generator together comprise a gas turbine engine. The method comprises determining, via one or more controllers, an operating condition of the aircraft based at least on a weight on wheels (WoW) signal and a throttle lever position. The WoW signal produces a first mode or a second mode different from the first mode, and the throttle lever position defines at least a takeoff position and an idle power position.
US10981660B2
Hybrid propulsion engines for aircraft are described herein. An example hybrid propulsion engine includes a propulsor and a gas turbine engine to drive the propulsor during a first mode of operation. The gas turbine engine has a core air intake. The hybrid propulsion engine also includes an electric motor to drive the propulsor during a second mode of operation and a damper disposed in the core air intake of the gas turbine engine to block airflow through the core air intake during the second mode of operation.
US10981656B2
A device to orient a riser of a parachute. The device can include a twist body that is includes a slot through which the riser passes. The slot includes a twist to change the orientation of the riser from a relatively high-profile orientation to a relatively low-profile orientation. The device can also include a link to connect the riser to the suspension lines on the canopy.
US10981655B2
A system for processing recirculation air recovered from an aircraft cabin includes a mixing chamber and a carbon dioxide removal system. The carbon dioxide removal system has an inlet for recovered recirculation air from the aircraft cabin, an outlet to the mixing chamber; at least two assemblies of carbon dioxide sorbent that are thermally linked, a CO2 outlet valve; and a controller for managing desorption of carbon dioxide from the sorbent depending on aircraft status. The mixing chamber has an inlet from the carbon dioxide removal system, an inlet from an environmental control system, and an outlet connected to the aircraft cabin.
US10981648B2
An aircraft includes a canard having a trailing edge, a forward swept and fixed wing having a horizontal plane and a trailing edge, and a plurality of tilt rotors. At least one of the plurality of tilt rotors is attached to the trailing edge of the canard and at least one of the plurality of tilt rotors is attached to the trailing edge of the forward swept and fixed wing. The aircraft also includes a T-tail having a horizontal plane, where the horizontal plane of the T-tail is at a height that is higher than the horizontal plane of the forward swept and fixed wing.
US10981646B2
A landing gear including an outer cylinder rotatably coupled to a frame of an aircraft about a trunnion axis of rotation, a shock strut assembly movably coupled to the outer cylinder so as to reciprocate along a longitudinal axis of the outer cylinder, and a shrink mechanism including a first shrink link member pivotally coupled to the outer cylinder, a second shrink link member coupling the first shrink link member to the shock strut assembly, a crank member pivotally coupled to the outer cylinder, a drive member coupling the crank member to a walking beam (a.k.a. retract actuator beam) of a landing gear retract mechanism, and a driven member coupling the crank member to the first shrink link member.
US10981642B2
A method for manufacturing a modular lifting surface from a standard lifting surface, the modular lifting surface includes a central support structure including an upper skin, a lower skin and at least a first spar. The method includes providing the upper skin and the lower skin which are suitable for any of various sizes of a modular lifting surface for the standard lifting surface, wherein the upper skin and lower skin correspond to a standard upper skin and the lower skin conforms to a standard lower skin.
US10981641B2
Methods and structures are disclosed. An example method includes: rotating a tubular mandrel about a longitudinal axis of the tubular mandrel; depositing a composite material on an inner surface of the tubular mandrel to form a composite tubular member on the inner surface of the tubular mandrel; inserting and expanding an inner expandable mandrel within the composite tubular member to cause the inner expandable mandrel to press the composite tubular member against the inner surface of the tubular mandrel; curing the composite tubular member; removing the inner expandable mandrel; placing a frame within the composite tubular member; and removing the tubular mandrel so as to obtain the composite tubular member with the frame placed therein.
US10981633B2
A surfboard with a surfboard body (1) extending along a longitudinal direction (L) and having an upper surface and a bottom surface. An electrical battery pack (2) is removably positioned in an upper compartment accessible from the upper surface. An electrically driven water-jet configured to propel the surfboard is provided with electrical power from the electrical battery pack. The electrically driven water-jet is provided in a propulsion module (3) that is removably positioned in a lower compartment accessible from the lower surface. The upper compartment and the lower compartment partly overlaps each other as seen along the longitudinal direction (L).
US10981631B2
A boat hook assembly includes a clamping assembly, which is attachable to a pole. The clamping assembly includes a mechanical clamp in one embodiment and a magnetic clamp in another embodiment adapted to temporarily secure a boat hook which is configured to connect to a receiving member on a boat dock. The boat hook is configured to receive a boat line extending from the boat. The temporary securement of the boat hook by the clamping assembly is overcome by an operator moving the pole in a manner to release the clamping assembly from the boat hook, wherein the boat remains connected to the dock by the boat hook and the extended boat line. The boat hook assembly includes structural element and arrangements to prevent unintentional release of the clamping assembly from the boat hook.
US10981622B2
The invention obtains a hydraulic pressure controller whose control of a braking force is suppressed from becoming unstable. The invention also obtains a hydraulic brake system that includes such a hydraulic pressure controller, and a bicycle. A hydraulic pressure controller 110 controls hydraulic pressure of a brake fluid that is at least supplied to a front-wheel braking section 17 of a bicycle 200, and includes: a base section that is formed with a channel, through which the brake fluid flows, therein; a valve that is attached to the base section and opens and closes the channel; and a coupling section that couples the base section to the bicycle 200. The coupling section is coupled to a turning section 10 of the bicycle 200, the turning section 10 turning about an axis of a head tube 1A.
US10981614B2
A seat structure includes a substrate structure and a pad structure affixed to a top surface of the substrate structure. The seat structure has a support region configured to provide a support for a user's buttocks, and a downwardly sloped nose portion. The seat structure is bump-less in that there is no raised portion at an area between the user's legs which would extend upwardly from adjacent laterally outward portions.
US10981609B2
A trailer truck is the combination of a truck and one or more trailers used to haul freight. A trailer attaches to the truck via a trailer coupling (hitch), with much of its weight borne by the truck. The result is that both the truck and the trailer will have a distinctly different design than a rigid truck and trailer. Exemplary vehicles are provided, such as heavy duty trucks having truck bodies with improved aerodynamic characteristics, including improved drag coefficients.
US10981606B2
A thermoplastic composite article comprising a porous core layer comprising a plurality of reinforcing fibers, a lofting agent and a thermoplastic material is provided. In certain instances, the article further comprises a skin layer disposed on the core layer and an adhesive layer between the core layer and the skin layer. In some configurations, the adhesive layer comprises a thermoplastic polymer and an effective amount of a thermosetting material to provide a post-molding peel strength between the skin layer and the post lofted core layer of at least 0.5 N/cm (in either or both of the machine direction or cross direction) as tested by DIN 53357 A dated Oct. 1, 1982.
US10981604B2
A vehicle bulkhead structure may include a dash panel; a pair of front side members spaced apart from each other and coupled to the dash panel; and a plurality of reinforcement members coupled to a front surface of the dash panel, wherein some of the plurality of reinforcement members support each front side member.
US10981600B2
A vehicle drive unit is supported by a vehicle frame of a vehicle. The vehicle drive unit includes a housing including a first case and a second case integrally joined together along a coupling plane to form a sealed space therein, a drive member accommodated in the sealed space to generate a travel driving force of the vehicle, and a mount member interposed between the housing and the vehicle frame to support the housing from the vehicle frame. The first case and the second case respectively include a first attachment portion and a second attachment portion to which the mount member is attached, and the first attachment portion and the second attachment portion are installed in a single region intersecting with the coupling plane.
US10981597B2
The purpose of the present invention is to perform mirror control as driving control when recognizing a mirror in front of the vehicle. By adopting this configuration, it is possible to perform appropriate driving control for automated driving. Another purpose of the present invention is to perform mirror processing as recognition processing when recognizing a mirror in front of a vehicle. By adopting this configuration it is possible to perform appropriate recognition processing in automated driving.
US10981589B1
A steering lever mechanism for a mower vehicle includes a lever assembly and a base which is fixed to the mower vehicle for mounting the lever assembly to the mower. The lever assembly includes a pivot assembly and a lever portion. The lever portion is pivotably mounted to the pivot assembly for rotation about a longitudinal axis between an inboard position and an outboard position. The pivot assembly is also pivotably mounted to the base for rotation of the pivot bracket portion and the lever portion about a transverse axis between a rear position, an intermediate neutral position and a forward position. A rotation-measuring device is associated with the base and the pivot assembly for measuring the forward and rear rotation of the lever assembly.
US10981577B1
A perception module receives frames of data from sensors onboard a vehicle and identifies objects surrounding the vehicle based on the data. A fault detection module determines semantic information associated with the data, generates a score for each of the identified objects based on a correlation of each of the identified objects with the semantic information, and generates a score for the frames based on the scores for the identified objects. The fault detection module determines that the perception module: is operating normally in response to the score for the frames being less than a first threshold, has a fault in response to the score for the frames being greater than a second threshold, and needs inspection in response to the score being between the first and second thresholds.
US10981576B2
A vehicle having a control element for the speed, acceleration or direction of the vehicle, a computing device to generate a command in autonomous driving of the vehicle, and a command controller coupled between the control element and the computing device. In response to the command, the command controller initiates a test of a portion of the memory of the computing device. If the portion of the memory passes the test, the command controller forwards the command for execution via the control element of the vehicle; otherwise, the command controller blocks the command and/or issues a replacement command for the vehicle.
US10981570B2
A machine is disclosed. The machine may include a continuously variable transmission, a location or movement module, and a controller. The controller may receive a first signal indicating a transmission output speed for the machine. The controller may receive, from the location or movement module, a second signal indicating location or movement information of the machine. The controller may determine a traction value based on the first signal and the second signal. The controller may determine a rimpull limit value based on the traction value. The controller may provide the rimpull limit value to the continuously variable transmission, wherein the continuously variable transmission is to determine a transmission output torque of the machine based on the rimpull limit value.
US10981568B2
Redundant environment perception tracking for automated driving systems. One example embodiment provides an automated driving system for a vehicle, the system including a plurality of sensors, a memory, and an electronic processor. The electronic processor is configured to receive, from the plurality of sensors, environmental information of a common field of view, generate, based on the environmental information, a plurality of hypotheses regarding an object within the common field of view, the plurality of hypotheses including at least one set of hypotheses excluding the environmental information from at least one sensor of a first sensor type, determine, based on a subset of the plurality of hypotheses, an object state of the object, wherein the subset includes the at least one set of hypotheses excluding the environmental information from the at least one sensor, and perform a vehicular maneuver based on the object state that is determined.
US10981564B2
A computing system can be programmed to determine a location, speed and direction for a first vehicle. The computer can be further programmed to determine probabilities for predicted locations, speeds and directions of the first vehicle based on identifying the first vehicle and the driving environment. The computer can be further programmed to operate a second vehicle based on the determined probabilities for predicted locations, speeds and directions of the first vehicle.
US10981544B2
A wiper assembly (100) is provided, comprising a wiper arm (110), a wiper blade (120), and a coupling device (130) configured to enable connection of the wiper blade (120) to the wiper arm (110), wherein the coupling device (130) comprises a first part (140) being connected to one of said wiper arm (110) or said wiper blade (120), and a second part (150) being connected to the other one of said wiper arm (110) or said wiper blade (120). The first part (140) comprises an engaging section (142) being configured to provide an axial fixation of the first part (140) relative the second part (150), and at least one recess (144) configured to provide a rotational fixation of the first part (140) relative the second part (150), and wherein the second part (150) comprises a receiving section (152) configured to receive the engaging section (142) of the first part (140), a locking device (160) arranged radially outwards of said first part (140) and comprising at least one radial protrusion (162) configured to fit with said recess (144) of the first part (140), and a wall (170) surrounding said locking device (160), wherein said wall (170) comprises a constricted section (172) whereby an inner wall (174) of said constricted section (172) is configured to press the radial protrusion (162) radially inwards when the constricted section (172) is axially aligned with the radial protrusion (162).
US10981540B2
A vehicle theft-prevention apparatus can include a locking mechanism, at least one computing device, and a cylindrical body including a first portion and a second portion. The first portion can be configured to rotate about the second portion. The at least one computing device can be configured to determine that the locking mechanism has transitioned from an unlocked state to a locked state. In response to determining that the locking mechanism has transitioned to the locked state, the at least one computing device can disable an engaging component of the locking mechanism. The at least one computing device can be configured to receive, via a network, a command to enable the engaging component. In response to receiving the command, the at least one computing device can enable the engaging component of the locking mechanism.
US10981537B2
A seatbelt height adjuster includes a track, a slider slidably coupled to the track, slots in one of the track and the slider and teeth on the other of the track and the slider. The teeth are selectively engageable with the slots. The seatbelt height adjuster includes a D-ring supported by the slider and leaf springs disposed on opposite sides of the slider. The leaf springs are each engaged with the track and biasing the slider in opposite directions.
US10981535B2
Provided is a gas generator including a housing including a top plate, a bottom plate, and a peripheral wall, the bottom plate being axially opposite the top plate, and the peripheral wall including a gas discharge port and being located between the top plate and the bottom plate. In the gas generator, an internal space of the housing is separated into a first combustion chamber and a second combustion chamber by a partition wall axially and radially partitioning the internal space of the housing, the first combustion chamber being formed to accommodate a first gas generating agent and being on the top plate side, and the second combustion chamber being formed to accommodate a second gas generating agent and being on the bottom plate side. A first igniter and a second igniter are disposed at the bottom plate, the first igniter being configured to burn the first gas generating agent, and the second igniter being configured to burn the second gas generating agent. The partition wall includes a cylindrical portion and an annular portion, the cylindrical portion being formed to surround the first igniter and include a communication hole for making the first combustion chamber and the second combustion chamber to communicate with each other, and the annular portion being formed extend radially outward from a second opening on the top plate side of the cylindrical portion. A first opening of the cylindrical portion axially opposite the second opening is in contact with the first igniter, and an outer periphery of the annular portion is in contact with the peripheral wall of the housing, and, thereby, the first combustion chamber and the second combustion chamber are separated from each other.
US10981528B2
An occupancy sensor is provided for detecting the occupancy status of a wheeled mobility device securement system. The occupancy sensor may additionally confirm adequate “tightness” of the wheeled mobility device securement system and/or provide an indication of the magnitude of “tightness.” In one embodiment, the occupancy sensor comprises a spring-loaded follower that breaks the straight-line path of a wheeled mobility device tie down as it travels between two touch points. The follower is displaceable from an extended position to a compressed position in response to the magnitude of tension applied to the tie down. Proximity sensors are used to detect the displacement distance of the follower, thereby providing an indication of occupancy, adequate securement, and/or the magnitude of tension.
US10981526B2
A system includes a first DCDC converter arranged to output electrical power only to a first battery and to first loads in a first specified set. The first specified set includes loads provided to control and perform steering and braking. The system further includes a second DCDC converter arranged to output electrical power to loads isolated from the first loads provided to control and perform steering and braking.
US10981525B2
A rotary connector device capable of reducing the number of components and enhancing assembly workability provided with: a stationary member; a rotary member to be attached to the stationary member to be capable of relative rotation with respect to the stationary member, the rotary member including a steering wheel insertion hole into which an insertion convex portion of a steering wheel is to be inserted; and an intermediate stationary member provided to be movable between a locked position and a lock released position with respect to the rotary member, wherein the intermediate stationary member is provided with a regulating portion, the regulating portion being configured to, at the locked position, regulate relative rotation of the rotary member when the regulating portion is engaged with the stationary member.
US10981513B2
A center console structure includes a columnar part erected on a vehicle interior floor surface between a driver seat and a passenger seat and extends upward to the vicinity of the cushion surfaces of the seats and an upper body that is disposed above the columnar part, extends in a front-rear direction, has an upper surface part forming a center console surface, and accommodates a shift operation mechanism, in which the upper body extends forward of the columnar part that is cantilevered and has an extension part that is bent and then rises forward and obliquely upward in the front part thereof, a surface part of the extension part close to a sitting occupant forms an outer surface continuous with the center console surface and a portion of the extension part close to the front of the vehicle is locked to a rear projecting part of an instrument panel.
US10981503B2
A warning system implemented in a vehicle includes a proximity warning module and a display module. The proximity warning module is configured to detect an object approaching the vehicle and generate a proximity warning signal. The display module is configured to display a signal in the side area when the proximity warning signal is generated, where a position of the signal is determined based on a relative direction of the object to the vehicle.
US10981502B2
A system for monitoring vehicle dynamics and detecting adverse events during operation is presented. Position sensors attached to a vehicle are configured to identify a vehicle orientation (heading) as well as the vehicle's direction of travel (trajectory). A system controller connected to these position sensors can detect the difference between these two measurements. When the difference between these two measurements exceeds a safety threshold, it can be an indication of a slip event. A slip event can be caused by compromised traction or stability and may lead to a loss of vehicle control. The system controller can be configured to monitor various vehicle dynamics to detect these slip events. The system controller may be configured to track geolocations of slip events to create a database of historical slip events for determining location-based risk factors and prevention of future events.
US10981494B2
A three dimensional truck or SUV cab marker light apparatus comprising a container having a right circular cylinder structure with a shape determined by the number of walls used during assembly, each wall being formed from a generally flat sheet of a rigid material and a transparent material, the walls being assembled to form a container enclosing an interior region for a light-transmission source and having a lower surface for attachment to a cab roof without drilling holes into the cab roof and without installing wires through the cab roof.
US10981491B2
An in-vehicle light apparatus for a vehicle is provided and includes lamp radar units. The lamp unit includes a light source and a reflector arranged around the light source and outputting light from an opening area of the reflector to a predetermined region including in a first direction. The radar unit is provided on a lower or upper side of the lamp unit and includes a circuit board having a board surface arranged in a substantially horizontal state and an antenna unit that transmits an electromagnetic wave and receives a reflected wave in a second direction. The opening area extends in a third direction different from the first direction and the second direction in plan view, and a direction perpendicular to the second direction on the board surface is a direction intersecting the first direction and non-parallel to the third direction.
US10981477B2
In a car seat configured to cover a surface of a urethane pad by a trim cover, the trim cover is formed by sewing up a plural number of trim cover members with each other by chain stitch sewing, and by joining a surface on the back side of a portion where the plural number of the trim cover members are sewn up with each other by chain stitch sewing to a flat surface of the surface of the urethane pad by an adhesive.
US10981476B2
A ventilation apparatus for a seat of a vehicle includes: a main duct configured such that a first end thereof is connected to a blower and a second end thereof is coupled to a seat frame so as to allow air to flow therebetween; and a connecting duct configured such that a first end thereof is connected to the second end of the main duct and a second end thereof is connected to a seat pad, and formed in a bellows shape having a variable length so as to allow air to flow between the seat frame and the seat pad even if a spacing distance between the seat frame and the seat pad is changed.
US10981470B2
A utility task vehicle (UTV) includes a frame having frame rails and a battery assembly positioned laterally between the frame rails. The battery assembly includes a battery housing and a battery array having a plurality of battery cells. The battery array is positioned within the battery housing and the battery assembly provides support for or is located under a floor of a cabin of the utility task vehicle.
US10981469B2
A desired departure temperature is determined for a battery, having a temperature, in a vehicle based at least in part on trip information associated with a trip. A temperature controlling system is used to bring the temperature of the battery towards the desired departure temperature, wherein the vehicle begins the trip with the battery at the desired departure temperature.
US10981463B2
A charging system for autonomous transport vehicles including at least one charging contact disposed on each pick floor level of a storage and retrieval system, each of the at least one charging contact being located at a transfer station, at least one power supply configured to supply power to the at least one charging contact, and a controller in communication with the transfer station and being configured to communicate information relating to a transfer of items between the transfer station and a predetermined one of the autonomous transport vehicles and to apply power from the power supply to the at least one charging contact for charging the predetermined autonomous transport vehicle corresponding to the transfer and located at the transfer station, wherein the controller is configured to supply power to the charging contacts simultaneously with the predetermined autonomous transport vehicle exchanging items related to the transfer at the transfer station.
US10981462B2
To provide a system of low cost and low loss capable of the supply of electric power according to characteristics of each of a plurality of motors from a single battery. A power supply system for a vehicle of the present invention includes: a high-voltage battery; a first inverter which connects with the high-voltage battery; a motor described later which connects with the first inverter; a high-voltage DCDC converter which is connected to the high-voltage battery and steps down the voltage of the high-voltage battery; a second inverter which connects with the high-voltage battery; and a motor described later which connects with the second inverter.
US10981461B2
A method and device or electrically charging electric vehicles, wherein a cooling unit makes available a cooling medium, wherein the cooling unit is designed to cool, with the cooling medium, at least two electric charging devices and at least two power electronics apparatuses which are designed to electrically charge electric vehicles.
US10981460B2
A vehicle charging device includes a charger to electrically charge a storage battery mounted in an electric vehicle. The vehicle charging device comprises: a housing in which the charger is housed; a charging cable having one end side and an opposite end side, the one end side including an end portion connected to the charger, the opposite end side including an end portion connected to a connector to be connected to the electric vehicle, the opposite end side including a portion pulled out from an inside of the housing to an outside of the housing; and a cable holder provided on one side surface of the housing, the cable holder holding an intermediate portion of the charging cable pulled out to the outside of the housing. The cable holder includes: a cable holder guide portion secured to the one side surface of the housing; and a cable holder movable portion attached to the cable holder guide portion such that the cable holder movable portion is movable in a height direction of the housing.
US10981448B2
A vehicle may include a CVT unit or a power source which requires ambient air. An air inlet for an air intake system coupled to the CVT unit or the power source which requires ambient air may be provided in a side of a cargo carrying portion of the vehicle. The vehicle may include a rear radius arm suspension.
US10981439B2
A glazing includes two contiguous windows, the glazing including on the one hand a single profiled body situated facing a part of the edge surface of the windows, without contact with the edge surfaces of the windows, and on the other hand, two curved exterior coverings that each include a portion situated farther toward the exterior than the profiled body and that has an exterior face that is situated in continuity with the exterior face of the window and a portion against a part of the edge surface of the windows, the exterior coverings being flexible, with a Shore A hardness between 45 and 90 inclusive.
US10981436B2
A ventilation system for a mobile structure, in particular a motor vehicle, includes: a variably adjustable filter device including at least one controllable, variable filter characteristic with regard to a pollutant class; means for collecting information about the air quality in the surroundings of the mobile structure and in particular information about the air quality in an interior of the mobile structure; and a control unit for varying filter characteristics of the filter device in a variable, in particular continuous, manner, on the basis of the information about the air quality.
US10981430B2
A roof-type air conditioner for vehicles may include an evaporator to discharge cold air to the internal of a vehicle, and a conveying unit to move the evaporator in a longitudinal direction of the vehicle on a ceiling of the vehicle such that the evaporator is disposed to the ceiling of the internal of the vehicle and positioned to a region required for cooling.
US10981424B2
There is provided a control arm comprising a shell-like shell of a first material and a reinforcement of a plastic material, wherein the reinforcement has a flex-element which protrudes therefrom and which can be supported or guided by means of a vehicle structure in order in the event of jounce and/or rebound of the suspension to produce a resilient action equivalent to a conventional spring.
US10981423B2
A system for mounting a housing and an insert to a tire includes a housing configured to be installed in a tire, wherein the housing has a top opening. The system also includes at least one anchor connected to a side of the housing in an un-deployed configuration. The system further includes an insert configured to be inserted into the top opening of the housing. The at least one anchor projects outward into the tire when the insert is inserted into the top opening of the housing.
US10981421B2
A tire comprises shoulder blocks and middle blocks having ground contacting surfaces respectively provided with narrow grooves and each including a circumferential groove portion. The tire further comprises bead apex rubbers each extending from respective one of bead cores and each of the bead apex rubbers includes an extended portion extending to a position on an inner side in a tire axial direction of a first reference line passing through the circumferential groove portion of each of the shoulder blocks.
US10981417B2
A pneumatic tire 1 comprises a carcass 6 comprising at least one carcass ply 6A extending between bead portions 4 via sidewall portions 3 and a tread portion 2. The carcass ply 6A comprises strip-shaped ply pieces 11 longer in a tire radial direction than in a tire circumferential direction arranged circumferentially. Each of the ply pieces 11 comprises a plurality of carcass cords 12 arranged in parallel in the tire radial direction and at least partly overlapping each other with the ply pieces 11 circumferentially adjacent. At least one of the carcass cords 12 arranged in at least one of side edge portions 11e in the tire circumferential direction of each of the ply pieces 11 having a diameter (Ce) smaller than a diameter (Cc) of at least one of the carcass cords 12 arranged in a center portion 11c of each of the ply pieces 11.
US10981402B2
A method for forming a Data Matrix Code or like two dimensional code on a beverage can tab uses a laser having a focal ratio of between 40 and 70 to produce spots having an average diameter of between 200 and 400 microns. The code is smaller than 6 mm by 6 mm, at least 12 modules by 12 modules, and smaller than 21 modules by 21 modules, thereby providing sufficient quantity of unique codes for use with commercial beverage can quantities. Preferably each module is formed by one laser spot. Alternatively, nine spots may be used to form a module.
US10981399B2
In an example, a media guide assembly includes a support structure, a first media guide, and a second media guide moveably coupled to the support structure. In that example, the second media guide includes a surface that generates a wedge effect to move the second media guide to a level when contacted by a force. In another example, an example print apparatus includes a support structure, a first media guide, and a second media guide substantially parallel to the first media guide with respect to a media advance direction. In that example, the second media guide includes a position control mechanism to place force on a media path surface of the second media guide towards a rest position where the media path surface of the second media guide is substantially parallel to the media path surface of the first media guide.
US10981395B2
A printer includes a printing portion configured to print on a print medium, a ribbon supply shaft configured to hold an ink ribbon to be supplied to the printing portion, and a ribbon roll up shaft configured to roll up the used ink ribbon, wherein the ribbon supply shaft is provided movably between a ribbon supply position where the ink ribbon is supplied to the printing portion, and a ribbon replacement position where the ribbon supply shaft is attachable to and detachable from the printer, and rotated in the direction in which the ink ribbon is rolled up in the middle of moving from the ribbon replacement position to the ribbon supply position.
US10981393B2
A liquid ejecting apparatus includes: a recording head that ejects liquid; a pressurizing mechanism that supplies the liquid under pressure; a valve-mechanism provided between the pressurizing mechanism and the recording head, the valve-mechanism including a liquid storage chamber storing the liquid supplied under pressure, a pressure chamber that is provided closer to the recording head than to the liquid storage chamber and stores the liquid, and a valve body that moves in a valve opening direction according to a negative pressure in the pressure chamber to communicate the liquid storage chamber with the pressure chamber; and a pressure control section controlling a pressure of the liquid supplied from the pressurizing mechanism to the valve-mechanism. The pressure control section controls the pressure of the liquid that is supplied under pressure by the pressurizing mechanism to the liquid storage chamber, to move the valve body in the valve opening direction.
US10981382B2
A liquid discharge head includes a plurality of nozzles from which a liquid is discharged, the plurality of nozzles arrayed in one direction, a plurality of pressure chambers communicating with the plurality of nozzles, respectively, the plurality of pressure chambers arrayed in the one direction, a common supply channel communicating with each of the plurality of pressure chambers, a common collection channel communicating with each of the plurality of pressure chambers, and a damper disposed outside an array of the plurality of pressure chambers in the one direction, and configured to form an inner surface of at least one of the common supply channel and the common collection channel.
US10981379B2
There is a provided a drive circuit including a power supply voltage control circuit that controls supply of a power supply voltage to a first device and a second device, a first drive signal output circuit that includes a first detection circuit detecting a voltage value of the power supply voltage, and outputs a first drive signal, a second drive signal output circuit that includes a second detection circuit detecting the voltage value of the power supply voltage, and outputs a second drive signal, a first fuse having one end electrically coupled to a first detection circuit and a first selection circuit, and the other end electrically coupled to the power supply voltage control circuit, and a second fuse having one end electrically coupled to a second detection circuit and a second selection circuit, and the other end electrically coupled to the power supply voltage control circuit.
US10981378B2
The disclosure provides an image-forming apparatus which can remove deposits on the filter. If there is input via operation buttons indicating that ink supply paths are closed off, a CPU drives a pump while a nozzle cleaning valve and an exhaust waste fluid valve are open, and an atmospheric valve and a nozzle waste fluid valve are closed. The pressure in an exhaust waste fluid flow path and inside an exhaust cap becomes negative, such that cleaning fluid flows from a cleaning fluid bottle into a cleaning fluid flow path, a nozzle cleaning valve, a cleaning fluid flow path, a nozzle cap, a filter, an ink supply flow path, and an exhaust flow path. Therefore, deposits adhered to the filter from the ink passing through the filter separate from the filter due to the cleaning fluid passing through the filter, and these deposits flow into the exhaust flow path.
US10981368B2
Provided are a decorative glass panel having a three-dimensional metal design and a manufacturing method for the decorative glass panel, the method exhibiting enhanced productivity. A decorative glass panel 10 includes: a glass substrate 15; an adhesive layer 11 formed on the glass substrate 15; a non-uniform pattern layer 12 formed on the adhesive layer 11; and a vapor-deposited metal layer 13 formed on the non-uniform pattern layer 12. In the glass substrate 15, a section that is a portion of a back surface of the glass substrate 15 and that is bent from a flat surface section 30 to an upright section 31 forms a curved surface 32. The non-uniform pattern layer 12 has, in a surface facing the vapor-deposited metal layer 13, which is a top surface thereof, a non-uniform pattern formed by depressions 40 and protrusions 41.
US10981366B2
An object is to provide an optical polyester film and a transparent conductive film that are superior in transparency, heat resistance, optical properties, and adhesion. The optical polyester film includes: a base material containing a polyester resin containing a unit (A) of the following formula (1); and at least one functional layer disposed on at least one surface of the base material, wherein the at least one functional layer is selected from the group consisting of a hard coat layer, a transparent conductive layer, an anti-reflection layer, a gas barrier layer, and an adhesive layer.
US10981362B2
A method to produce a veneered element, the method including applying a first layer on a substrate, applying a second layer on a veneer layer, applying the veneer layer with the second layer applied thereto on the first layer, such that the second layer is facing the first layer, pressing the first layer, the second layer and the veneer layer together to form a veneered element, thereby material originating from the second layer permeates into the veneer layer, and wherein, after pressing, the first layer is visible through a crack, cavity, hole and/or knot of the veneer layer. Also, a veneered element.
US10981359B2
A glazing, and in particular an automotive glazing, includes a laminated glazed element including an exterior glass sheet, an interior glass sheet and a plastic interlayer sheet that is located between the two glass sheets and including at least one light-emitting diode that is located under a peripheral edge of the interlayer face of the exterior glass sheet, wherein the emitting face of the light-emitting diode is located facing at least a part of the edge face of the interior glass sheet and wherein the glazing includes a profiled bead including an exterior lip an interior lip and a body, with the body being located a distance away from, and not in contact with, the emitting face of the light-emitting diode.
US10981357B2
A glass article includes a first outermost pane, a second outermost pane disposed opposite the first outermost pane, and a transparent interlayer disposed between the first and second outermost panes. The first outermost pane has a thickness of from 1.1 to 4.0 mm, and has a first glass transition temperature. The second outermost pane has a thickness of from 0.3 to 1.05 mm, and has a second glass transition temperature. The second glass transition temperature of the second outermost pane is from 1 to 40° C. greater than the first glass transition temperature of the first outermost pane.
US10981348B2
An apparatus for introducing transverse trapezoidal corrugations into a traveling web is provided, and includes a plurality of corrugating rollers for imparting corrugations to the web. In disclosed embodiments four such rollers are provided in a roller train defining respective first, second and third nips therebetween, wherein the teeth of the first and second rollers have rounded distal faces and those of the third and fourth rollers have flattened distal faces. Methods of yielding a trapezoidal corrugated web also are disclosed.
US10981341B2
The present invention relates to a molded object and a method for manufacturing the same. The molded object according to the present invention has high density and enhanced properties such as flexural strength or tensile strength, has a small weight change caused by moisture absorption even when used for a long period of time, and has small changes in flexural strength, tensile strength and the like, and therefore, is suited to be used as household materials, industrial materials or the like.
US10981337B2
A process for producing a component from a fiber-reinforced plastic with a thermoset matrix. The process includes the steps providing a first and second thermoset prepreg layer, producing a cutout in the first thermoset prepreg layer, providing a thermoplastic layer in the semifinished product between the first and the second thermoset prepreg layer in the region of the cutout, and manufacturing the component with a first and second thermoset layer and a thermoplastic layer in the region of the cutout, where the thermoplastic layer is locked between the two thermoset layers. The component may be used in a vehicle, where the component has been produced from a fiber-reinforced plastic with a thermoset matrix by the abovementioned process.
US10981321B2
Aspects disclosed herein relate to forming on a substrate fastener elements suitable for use in touch fastener by employing vibration forming methods. The processes described provide for a greater flexibility in manufacturing than prior methods and overcome certain limitations in prior forming techniques. Further, the product made can embody a variety of different configurations suitable for a given application. Employing vibration forming methods, such ultrasonic forming methods, allows for the use of a wider variety of substrate material than materials used with convention methods of touch fastener formation.
US10981317B2
A device for producing plastic pipes may include an extruder with a die head and a corrugator, into which a molten plastic tube is introduced by means of the die head to mold the plastic pipe. The corrugator has a molding section, in which molding jaws are guided in pairs in the production direction; in an inlet section of the corrugator, the molding jaws are brought together to form molding jaw pairs towards the start of the molding section; and in an outlet section of the corrugator, the molding jaw pairs are moved apart from each other from the end of the molding section. Each molding jaw has a first and second guide pins and the molding jaws are guided in the guiding apparatus in that the first and second guide pins engage, with respective free ends, in first and second guide grooves of the guiding apparatus.
US10981312B2
An injection unit for a molding machine includes a plasticizing cylinder having at least two grooves, and a carrier part having a notch. The plasticizing cylinder is arranged in the notch. The at least two grooves are spaced apart axially from each other. At least two engaging elements are provided, which engage with the at least two grooves, in order to create a positive-locking connection between the plasticizing cylinder and the carrier part, through which an axial movement of the plasticizing cylinder relative to the carrier part is inhibited.
US10981307B2
A method of producing a molded product includes preparing a mold for insert molding, setting an insert member, forming a cavity in a condition in which the insert member is disposed by closing the mold and injecting a molten resin into the cavity. The mold for insert molding includes first and second molds, and the first mold has a guide surface provided at a part corresponding to a trunk portion of the molded product within a wall surface defining a groove portion which constitutes a part of the cavity. The insert member is set at the groove portion of the first mold while the projecting portion being guided by the guide surface.
US10981304B2
A method of nanoscale patterning is disclosed. The method comprises: mixing predetermined amounts of a first solvent and a second solvent to generate a solvent, the first solvent and the second solvent being immiscible with each other; dissolving a solute material in the solvent to generate a coating material, the solute material having solubility that is higher in the first solvent than in the second solvent; and applying the coating material onto a substrate to form a plurality of pinholes in the coating material. The formation of the plurality of pinholes is associated with suspension drops mostly comprised of the second solvent, separated from the solute material dissolved in the first solvent, in the coating material. A method of making a stamp with a nanoscale pattern is also disclosed based on the above method.
US10981300B2
An induction heating system for molding a thermoplastic article includes a first mold and a second mold defining a mold cavity therebetween for molding the thermoplastic article, a first metallic susceptor as part of or adjacent to the first mold, a first armature-supported induction coil array in proximity to the first metallic susceptor, and a first induction generator electrically coupled with the first armature-supported induction coil array.
US10981297B2
A system and method for processing a supply of post-consumer scrap linear low density or low density polyethylene film into near-virgin quality blown film product. The method includes tearing the supply of film in a shredder, wherein the surface area of the film is exposed, including delaminating the film. The torn supply of film is washed in a water bath including a surfactant. The film is agitated in the bath containing the surfactant wherein contaminants on the film are removed from the film. The washed film is ground into smaller pieces and additional washing of the ground film in a rotating friction washer and a sink float tank occurs wherein additional contaminants are removed from the film. The ground film is then dried and compacted without addition of water into granulated objects of near-virgin quality blown film product.
US10981293B2
This document describes systems and processes for forming synthetic molded slabs, which may be suitable for use in living or working spaces (e.g., along a countertop, table, floor, or the like).
US10981286B2
A cutting member (1) for a shaving cartridge includes a front side, a back side opposing the front side, and a flat cutting portion (2) with a cutting edge portion (4). Further the cutting member includes a first bent portion (8), an intermediate portion (11), a second bent portion (9) and a base portion (10) that are made out of one single piece of material. The first bent portion is integral with the flat cutting portion. The first bent portion is convex on the back side of the cutting member, and the second bent portion is concave on the back side of the cutting member. The proposed shape of the cutting member resembles an “S” shape or a question mark shape.
US10981285B2
An electrically operable clipper has a body portion and a head portion, wherein the head portion includes a movable cutter and a fixed comb. The clipper includes an internally located electric motor operable to move the movable cutter. The clipper further includes an operating switch movable between an off position, an operating position and a reset position, wherein the reset position operates a motor reset module of the clipper.
US10981281B2
The present disclosure relates to a low mass system for releasably securing a robotic arm to a spacecraft and also securing various payloads to the robotic arm and to each other, permitting the robotic arm to be both moved from one location to another suitably equipped location on a spacecraft to another and to allow the free end of the robotic arm to be secured to any payload also similarly equipped such that this payload may be manipulated by the robotic arm.
US10981280B2
A retrieval device for retrieving items within a confined space with limited access, said device comprising: (a) an elongated body having a front and rear and a longitudinal axis; (b) a clamping mechanism comprising at least a set of jaws disposed at said front, said jaws being configured to actuate between closed and open positions, said clamping mechanism also comprising at least one actuating member connected to said jaws and at least partially disposed in said body; (c) an actuator laterally offset from said axis and beside said at least one actuating member, said actuator operatively connected to said at least one actuating member to actuate said jaws between said closed and opened positions; and (d) at least one camera disposed proximate said motor and offset from said axis, said at least one camera having a field of view of at least a portion of said jaws.
US10981264B2
A working head for a hydraulic power tool. The working head includes a head frame and a first moveable die head configured to move along the working head frame. The first moveable die head is configured to receive a first moveable die comprising a first body length and a second die head is adapted to receive a second die comprising a second body length. At least one of the moveable die or the stationary die comprises an elongated die.
US10981261B2
A clamping assembly includes a body defining a retaining area and at least one coupling element. The body further includes a first leg having an adjustable engagement member and a second leg positioned at an angle less than 90° relative to a horizontal axis. The clamping assembly further includes a rod having a first end coupled to the at least one coupling element of the body. The rod is operative to drive the body in a direction toward the first leg in response to a force directed toward a second end of the rod.
US10981260B2
An abrasive product having an abrasive surface, a belt of an abrasive product, a roll of an abrasive product and a method for manufacturing an abrasive product. An abrasive product includes a backing and an abrasive surface. The abrasive surface includes at least a first abrasive area and a second abrasive area, wherein abrasive properties of the first abrasive area are different from abrasive properties of the second abrasive area.
US10981258B2
An adjustable stroke mechanism for a random orbital machine including a housing having a wall enclosing a cavity, an adjuster ring surrounding the housing and having a first set of gear teeth along a first portion of an inner surface, and a second set of gear teeth along a second portion of the inner surface, a counterweight having gear teeth on an exterior surface disposed within the housing, and a bearing carriage having gear teeth disposed within the housing. At least one counterweight gear that meshes with the gear teeth of the counterweight and the first set of gear teeth of the adjuster ring, and at least one bearing carriage gear that meshes with the gear teeth of the bearing carriage and the second set of gear teeth of the adjuster ring, so that movement of the adjuster ring causes movement of both the counterweight and the bearing carriage.
US10981257B2
An optical fiber polisher includes a polishing mechanism, a platen, and a memory for storing operational parameters entered by a user. The optical fiber polisher includes a processor to control a pressure applied by the polishing mechanism and a rotational speed of the platen, including causing a ramping down of at least one of the pressure and the rotational speed based on the operational parameters.
US10981255B2
In a method for the documented tightening or tightening up of a heavily loaded screw connection of a threaded bolt and a nut screwed on the threaded bolt by using an axially operating tensioning device and a process control unit provided with a documentation module, the screw connection is identified by scanning an identification provided on the screw connection and data determined by scanning the identification is stored in the documentation module. The screw connection is lengthened by the tensioning device by axially pulling on a threaded end of the threaded bolt and a tightening force (FA) and/or a tightening pressure (PA) exerted by axially pulling on the threaded end is stored in the documentation module. After lengthening, the nut is turned by using a hand torque wrench and an actually exerted hand torque applied for turning the nut is stored in the documentation module.
US10981249B2
Provided is an epoch-making method in which an original sheet is continuously fed, and a rectangular electrode sheet with a tab can be cut out from the original sheet with a normal laser beam during the continuous feeding.
The original sheet 1 is continuously moved. An ear portion 1b is separated from an electrode portion 1a with a first laser beam L1 in an ear portion separating region provided in the middle of movement of the original sheet 1, is taken up at a position where the ear portion 1b is separated, in a direction separated from a running direction of the electrode portion 1a, and the laser beam L1 is moved in the ear portion separating step to cut out a tab 5 connected to the electrode portion 1a, from the ear portion 1b. Thereafter, in the next cutting region, while tension T in the running direction of the electrode portion 1a is applied to a cut portion of the electrode portion 1a, the electrode portion 1a is cut at a predetermined interval with a second laser beam L2 to continuously form an electrode sheet 3 with the tab 5. Thereafter, the electrode sheet 3 with the tab 5 and the separated ear portion 1b are collected.
US10981246B2
A laser welding method according to the present disclosure includes a step in which a third material is interposed between a first material and a second material, which are made of the same type of metal so as to be weldable to one another, and at least one of which is provided with a protruding portion, wherein the third material is difficult to weld to the first material and the second material and has a through-hole portion into which the protruding portion is inserted. The method also includes a step in which, when the third material is interposed between the first material and the second material, a region corresponding to the protruding portion is irradiated with a laser beam from the first material side, and the first material and the second material are welded via the through-hole portion. In the step in which the third material is interposed between the first material and the second material, a first gap is provided between the protruding portion and the inner peripheral face of the through-hole portion, and a second gap corresponding to the plate thickness of the first material is provided between the first material and the second material in the region corresponding to the protruding portion.
US10981240B2
A saw tooth for a saw including a square saw tooth body to be mounted on a holder and for receiving inserts fastened to inwardly sloping seating surfaces on the cutting end of the tooth body. The inserts are provided with cutting edges. Between seating surfaces, the cutting end of the tooth body defines recesses for receiving intermediate members fastened therein. The intermediate members are provided with cutting edges, and the intermediate members abut the adjoining inserts to form a cutting surface about the periphery of the cutting end of the saw tooth and help protect the saw tooth body from damage including washout.
US10981238B2
Fast-acting and low-inertia actuators useable in various applications where a high force must be applied very quickly are disclosed. Power tools with detection systems configured to detect a dangerous condition between a person and a cutting tool are disclosed. In power tools, for example in a woodworking machine, a fast-acting and low-inertial actuator as disclosed herein can be used to retract a blade upon detection of a dangerous condition by a detection system. The actuator includes a charge of pressurized fluid and one or more electromagnets to selectively retain or release the pressurized fluid.
US10981228B2
A high-quality porous aluminum sintered compact, which can be produced efficiently at a low cost; has an excellent dimensional accuracy with a low shrinkage ratio during sintering; and has sufficient strength, and a method of producing the porous aluminum sintered compact are provided.
The porous aluminum sintered compact is the porous aluminum sintered compact (10) that includes aluminum substrates (11) sintered to each other. The junction (15), in which the aluminum substrates (11) are bonded to each other, includes the Ti—Al compound (16) and the Mg oxide (17). It is preferable that the pillar-shaped protrusions projecting toward the outside are formed on outer surfaces of the aluminum substrates (11), and the pillar-shaped protrusions include the junction (15).
US10981221B2
A mold assembly for use in forming a component having an outer wall of a predetermined thickness includes a mold and a jacketed core. The jacketed core includes a jacket that includes a first jacket outer wall coupled against an interior wall of the mold, a second jacket outer wall positioned interiorly from the first jacket outer wall, and at least one jacketed cavity defined therebetween. The at least one jacketed cavity is configured to receive a molten component material therein. The jacketed core also includes a core positioned interiorly from the second jacket outer wall. The core includes a perimeter coupled against the second jacket outer wall. The jacket separates the perimeter from the interior wall by the predetermined thickness, such that the outer wall is formable between the perimeter and the interior wall.
US10981219B1
The casting mold is provided with: the molding wall portion forming the internal space; the supporting portion supports the heater to the molding wall portion; and the filling port allows the molten metal to flow into the internal space. The heater has: the end portion (the fixed portion) supported by supporting portion; and the extending portion extended from the end portion. The internal space has: the supporting region accommodating the end portion; and the extending region accommodating the extending portion. The filling ports respectively open to the portions of the molding wall portion facing the supporting regions.
US10981206B2
A method for manufacturing a high precision hollow metallic component, by obtaining, through extruding or roll forming, a precursor hollow metallic profile having a constant cross section and at least one precursor chamber; positioning the precursor hollow metallic profile in a split-die cavity, wherein at least two walls of said split die cavity have essentially outside dimensions of corresponding walls of the high-precision hollow metallic component; introducing a mandrel made of at least two parts into the precursor chamber; plastically deforming the precursor hollow metallic profile by expanding the mandrel to obtain finished dimensions of the high-precision hollow metallic component; removing the mandrel from the finished chamber after reversing an expanding action. A variable cross section hollow metallic component, with at least two chambers obtained with the method, is also described.
US10981196B2
A silicone bond coat composition having a viscosity of less than 1,600 centistokes is applied to substantially all external surfaces of the article and then cured. A liquid silicone elastomer outer coat composition comprising a high viscosity first liquid silicone elastomer formulation and a low viscosity second liquid silicone elastomer formulation is then applied and cured to provide a protected article having a complex shape. Optimal coatings result from a careful balancing of component viscosities. In an embodiment, the first formulation has a viscosity greater than 300,000 centistokes, and the second formulation has a viscosity less than 6,000 centistokes, and the liquid silicone elastomer outer coat composition comprises from about 60 to about 40 percent by weight of the first formulation and from about 40 to about 60 percent by weight of the second liquid silicone elastomer formulation.
US10981184B2
Disclosed are a coating apparatus and a coating method. The coating apparatus includes a chamber, a support located in an interior space of the chamber and configured to support a substrate which is to be coated, an ejection nozzle configured to eject a coating material toward the support, and an electric field forming unit configured to form an electric field in a movement path of the coating material to provide kinetic energy for the coating material.
US10981183B2
The present invention relates to a handpiece for spraying on a fluid jet with a handpiece casing in which a nozzle element for forming the jet geometry of the fluid jet is accommodated. The present invention is based on the object of specifying a handpiece for spraying on a fluid jet which can be produced in a more simple and inexpensive manner, and proposes to satisfy the object in that a nozzle element be fixedly connected to an integrally formed nozzle holder which sealingly abuts against the outer circumferential surface of the nozzle element and is fixed relative to the handpiece casing.
US10981174B1
The present invention relates to methods for detecting targets by employing a temperature control system with a microfluidic device. The system allows for non-contact heating by employing an infrared emitter. In some instances, the system can be used in conjunction with a centrifugal microfluidic device. Optionally, a mask can be implemented to provide selective heating of desired assay areas of the device.
US10981168B2
A method of operating an active matrix electro-wetting on dielectric (AM-EWOD) device provides for enhanced mutual capacitance sensing using integrated impedance sensing circuitry. Array element circuitry of each array element includes actuation circuitry configured to apply actuation voltages to the array element electrode for actuating the array element, and impedance sensor circuitry integrated into the array element circuitry and configured to sense impedance at the array element electrode. The method of operating includes the steps of: perturbing a voltage applied to the array element electrode of a first array element; coupling the voltage perturbation to the array element electrode of a second array element different from the first array element; and measuring the output current from the sensor readout transistor of the second array element for sensing in response to the voltage perturbation. The method may be performed by an AM-EWOD control system executing program code stored on a non-transitory computer readable medium.
US10981166B2
Described herein are pipette driven well plates for nano-liter droplet storage and methods of using same. Embodiments may include an inlet, an outlet, a bypass channel, and a fluidic trap containing a valve covered by a removable covering, in which the fluid enters the fluidic trap when the removable covering is removed. The fluid enters either the fluidic trap or the bypass channel, depending on which of the fluidic trap or bypass channel has the lower hydrodynamic resistance. Embodiments may be used by closing the valve, introducing a first fluid to fill the fluidic trap and partially fill a bypass channel, opening the valve, removing the first fluid surrounding the valve, and introducing a second fluid into the fluidic trap, in which the introducing results in a mixture of the first and second fluids.
US10981163B2
This disclosure concerns a method of providing a hydrophobic coating on a microfluidic chip that promotes the discrete flow of at least one liquid. It includes applying the hydrophobic coating onto an area of the microfluidic chip. The disclosure further includes a microfluidic chip that provides discrete flow of at least one liquid.
US10981157B2
In one aspect, phosphine compounds comprising three adamantyl moieties (PAd3) and associated synthetic routes are described herein. Each adamantyl moiety may be the same or different. For example, each adamantyl moiety (Ad) attached to the phosphorus atom can be independently selected from the group consisting of adamantane, diamantane, triamantane and derivatives thereof. Transition metal complexes comprising PAd3 ligands are also provided for catalytic synthesis including catalytic cross-coupling reactions.
US10981156B2
The invention relates to oligomerization of olefins, such as ethylene, to higher olefins, such as a mixture of 1-hexene and 1-octene, using a catalyst system that comprises a) a source of chromium b) one or more activators and c) a phosphacycle-containing ligating compound. Additionally, the invention relates to a phosphacycle-containing ligating compound and a process for making said compound.
US10981154B2
Disclosed are a novel catalyst system which is a catalyst system for selectively oligomerizing olefin including ethylene and may trimerize and tetramerize olefin, different from the catalyst system for olefin oligomerization reported until now, and a method for preparing an olefin oligomer using same. The present invention provides a catalyst system for olefin oligomerization, including a ligand compound represented by Formula 1 or 2; a chromium compound; and a metal alkyl compound, and a method for preparing an olefin oligomer using same.
US10981138B2
An electrochemical reactor includes an ion ON/OFF surface switch operating as an ionic conductor, which includes a pair of electrodes, an electrolyte aqueous solution present between the pair of electrodes, a water-repellent porous fluororesin membrane disposed such that at least one surface thereof is in contact with the electrolyte aqueous solution and including a plurality of pores communicating with each other and a pressing equipment configured to pressurize the electrolyte aqueous solution. As such, electrolysis, a secondary battery and a capacitor, which uses the water-repellent porous fluororesin membrane as an ion ON/OFF surface switch, can be provided.
US10981137B2
Provided herein is a method for capturing DNA molecules in solution. The method may comprise: extracting DNA from a sample that comprises endogenous DNA and environmental DNA to produce extracted DNA; ligating universal adaptors to the extracted DNA; hybridizing the extracted DNA, in solution, with affinity-tagged RNA probes generated by: in vitro transcribing a library of fragmented reference genomic DNA that has been ligated to an RNA promoter adaptor, in the presence of an affinity-tagged ribonucleotide; binding the product with a capture agent that is tethered to a substrate in the presence of RNA oligonucleotides that are complementary to the adaptors, thereby capturing the hybridized DNA molecules on the substrate; washing the substrate to remove any unbound DNA molecules; and releasing the captured DNA molecules. A kit for performing the method is also provided.
US10981135B2
The invention relates to a method for treating a nanofibrillar cellulose hydrogel, wherein the method comprises the steps of: providing a nanofibrillar cellulose hydrogel, wherein the nanofibrillar cellulose is oxidized nanofibrillar cellulose, wherein the oxidation has been carried out through N-oxyl mediated catalytic oxidation of cellulose-based raw material, and has at most 50 μmol of aldehyde groups per gram of dry nanofibrillar cellulose; and subjecting the nanofibrillar cellulose hydrogel to a heat treatment.
US10981132B2
The present application provides aerosol processes for selectively incorporating properties of solid precursor particles into processed materials is provided. In one aspect, a carrier gas and a precursor mixture are injected into an aerosol generator. The precursor mixture includes solid precursor particles and a liquid component. One or more ultrasonic transducers are applied to the precursor mixture in the aerosol generator to aerosolize a portion of the precursor mixture that comprises solid particles that are smaller than a predetermined size. The aerosolized portion of the precursor mixture is transferred, via the carrier gas, into a reactor. The aerosolized portion in the reactor is then dried and sometimes reacted to produce solid product particles, and the solid product particles are collected in a particle collector.
US10981114B2
A system has an alkaline capture stream as an input, an alkaline depleted stream as an output, a carbon dioxide removal unit operation having a return stream as an output, and a series of electrolyzers, each electrolyzer to receive a CO2-rich input stream and produce an acidified output stream that is more acidic than the CO2-rich input stream, and to receive a return stream and produce a basified output stream that is more alkaline than the input return stream. A method of removing carbon dioxide from an atmosphere and generating hydrogen includes capturing carbon dioxide from an atmosphere in an alkaline capture solution, sending the alkaline solution as a CO2-rich input solution to a series of electrolyzers in a CO2-rich path, removing carbon dioxide from the acidified CO2-rich solution at a removal unit to produce a CO2-poor solution, sending the CO2-poor solution to the series of electrolyzers in a return path, and returning the return solution to the alkaline capture stream. An electrolyzer is also discussed.
US10981109B2
A wet scrubber (14) useful for reducing flue gas sulphur oxides and particulate matter comprising an at least first spray level arrangement (34) arranged horizontally in a wet scrubber tower (16). The at least first spray level arrangement (34) may comprise downwardly, upwardly, and/or combination downwardly and upwardly spraying nozzles (40). Arranged between the nozzles (40) is a plurality of single plates (76, 76A) and/or double plates (82) to direct flue gas flow into absorbent liquid or slurry atomized by the nozzles (40) for flue gas sulphur oxide and particulate matter reduction.
US10981108B2
Moisture separation systems and condensation devices for gas extracted from drilling fluids while drilling are provided. The condensation devices include a body having a first end and a second end and an exterior wall defining an interior surface, an interior passage providing a connection from the first end to the second end, and an angled support path within the interior passage, the angled support path extending from the interior surface and angled with respect to gravity. The angled support path is configured to direct a condensate away from the interior surface by the operation of gravity.
US10981107B2
Methods of recirculating clean air in an atmosphere of an enclosure comprise directing an input air stream from the atmosphere of the enclosure through a coiled duct at a rate sufficient to stratify the input air stream within the coiled duct according to a molecular weight of components of the input air stream and to form a heavy fraction stream and a light fraction stream, wherein the heavy fraction stream is relatively enriched in carbon dioxide as compared to the light fraction stream; withdrawing the heavy fraction stream from the coiled duct; and returning the light fraction stream from the coiled duct to the atmosphere of the enclosure.
US10981090B2
A method of manufacturing a base pipe for use in horizontal well completion, the method includes wrapping an inner shroud around a base pipe, the inner shroud is disconnected from the base pipe and forms seams along each edge of the inner shroud; fusing the seams together; allowing the inner shroud to cool, the inner shroud shrinks around the base pipe to form a friction lock between the base pipe and the inner shroud; laying a filter medium onto an outer shroud, wherein the filter medium is disconnected from the outer shroud, thereby creating a mesh filter medium/outer shroud sheet; wrapping filter medium/outer shroud sheet around the inner shroud, the filter medium is positioned between the inner shroud and outer shroud, thereby creating a second set of seams; and fusing the second set of seams together, thereby creating a second friction lock between the outer shroud and the inner shroud.
US10981068B2
A plurality of game apparatuses function as a master, a client, and an audience. The master and the client register each other by performing therebetween an authentication process. The authentication process is not performed between the master and the audience. The audience receives a beacon from the master and registers the master in an own apparatus while the audience is not registered in the master. The master and the client execute a predetermined program, exchanging data by communicating with each other. The audience receives the data exchanged between the master and the client, and executes the predetermined program using the received data, thereby watches a game which is progressed between the master and the client, as a spectator.
US10981065B2
An example of an information processing apparatus places an object in a virtual space. The information processing apparatus counts, for at least one type of the object, a placement number of the objects placed in the virtual space. The information processing apparatus presents candidates of a clear condition including a condition relating to the object, on the basis of the counted placement number, in a selectable manner for a user. The clear condition is used for determining that a game using the virtual space has been cleared. The information processing apparatus sets a candidate selected by the user, as the clear condition.
US10981060B1
A virtual reality system comprising a headset, a primary battery, a secondary battery (provides backup power), an output device which displays a 3-D virtual world (VW) based on the orientation and position of the headset. Swapping of the primary battery with a physical battery is viewed in the (VW) using virtual counterparts of the primary battery and the secondary battery in an output device in the headset. A user physically swaps the batteries while “seeing” the swapping taking place in the VW. The locations the user sees (through the headset) the primary battery and secondary battery correspond to their locations in the real world relative to the headset so that while the user physically feels (with his/her hands) the primary battery and the secondary battery the locations of the primary battery and the secondary battery in the VW correspond to what the user feels so that the swapping feels “real.”
US10981054B2
Various embodiments are directed towards employing one or more physical sensors arranged on or in proximity to a video game player to obtain biofeedback measures that are then usable to dynamically modify a state of play of a video game. The sensors may be connected or even unconnected to the game player, replace, or otherwise augment traditional physical game controllers. The sensors gather various biofeedback measures and provide such measures to a biofeedback application programming interface (API). Before and/or during video game play, the video game queries the biofeedback API to request inferences about the game player's state of arousal. The response to the query is then used to modify the state of the video game play. Where the video game is a multi-player video game, biofeedback measures from other game players may also be obtained and used to further modify the state of the video game play.
US10981052B2
A game processing system for processing of a game that provides interaction with a virtual character according to one embodiment includes a storage that stores action data for specifying one or more actions of the virtual character and one or more computer processors. The one or more processors execute computer readable instructions to determine an action of a player performed toward the virtual character based on detection information obtained by a head mounted display attached to a head of the player, cause the virtual character to perform a first action based on the action of the player and first action data among the action data for specifying the one or more actions of the virtual character, and suspend execution of the first action when a suspension condition is satisfied during the execution of the first action.
US10981048B2
Methods and apparatus are discussed for an electric-powered personal transportation vehicle with a composite board to support a weight of a user, one or more wheels driven by one or more electric motors, where the electric motors are powered by one or more batteries. The composite board includes a heterogeneous mix of individual components making up the composite board. The composite board includes i) a spine of the composite board made of a hardwood material connected to ii) sides of the composite board made of a vibration-dampening, high-density, foam.
US10981036B2
An aquatic training aid includes a paddle member for wearing by a swimmer, a variable diaphragm disposed within the paddle member, the variable diaphragm including a plurality of fitted blades arranged to form an aperture, and a housing peripherally framing the plurality of fitted blades. The variable diaphragm is adjustable to change the aperture from a first expanded position to a second contracted position, and hydrodynamic characteristics of the aquatic training aid when moved through water are affected by the change of the aperture. Controlling the aperture enables the swimmer to adjust the resistance provided by the aquatic training aid when it is moved through water.
US10981034B1
A system includes companion device that has movement sensors and a separate wearable device that has core contraction sensors. The companion device can be coupled to moving objects such as exercise equipment. Signals from the companion device and wearable device sensors are transmitted to a processor which analyzes the object movement signals and determines when a qualifying movement is performed which benefits from core contraction. Signals from the core contraction sensors are also transmitted to the processor and are used to determine if the core is contracted during the qualifying movement. If the core is contracted during the qualifying movement, the movement is a protected qualifying movement. However, if the core is not contracted during the qualifying movement the movement is an unprotected qualifying movement. The system can inform the user when unprotected qualifying movements are performed.
US10981033B2
Methods for instructing a user to perform head and neck exercises with head and neck apparatuses are disclosed. The apparatus may include a member operatively arranged with a valve mechanism with a threshold pressure. The apparatus may further include an acoustic apparatus, membrane, chromogenic material, or moveable element that may be configured to respond when the pressure within the member is greater in magnitude than the threshold pressure. The head and neck exercise apparatus may also include a member operatively arranged with an acoustic apparatus, membrane, chromogenic material, or moveable element that may be configured, without a valve mechanism, to respond when the absolute pressure within the member is greater in magnitude than a threshold absolute pressure.
US10981031B1
A multifunctional abdominal exercise wheel with a pulling rope includes a first wheel assembly. The first wheel assembly includes a first main support, a first main wheel, a chassis cap and a first sucking disc. An end of the first main support is detachably connected to the first main wheel. The chassis cap is connected to the first main wheel by a bearing. The first sucking disc is connected to the chassis cap by a sucking disc support, and a sucking disc spring is arranged between the sucking disc support and the chassis cap. Another end of the first main support is disposed with a first beam, and the first beam is perpendicularly connected to the first main support. The multifunctional abdominal exercise wheel may have advantages of reasonable structure, multiple functions, high utilization, easy to carry, and being capable of meeting various occasions for fitness at any time.
US10981030B2
A weighted bag having an outer shell and a handle assembly. The outer shell has a plurality of panels and at least one of one of a pair of slots and a first end loop assembly and a second end loop assembly spaced apart from the first end loop assembly coupled to the plurality of panels. The handle assembly has a handle grasping member and a strapping assembly, the strapping assembly extending from the handle grasping member and interfacing with at least one of the pair of slots and the first and second end loop assemblies so as to couple the handle assembly to the outer shell.
US10981026B2
Embodiments of the present disclosure provide a system for the mounting of obstacles on a climbing wall in a manner which allows the obstacles to take on a number of different positions or orientations without a need to remove the obstacle mounting element from the climbing surface or perform any other significant disassembly. Embodiments of the present disclosure thus provide obstacles that can be repositioned by children during play to instantly create a variety of unique climbing challenge courses.
US10981024B1
A fire fighting vehicle includes a front axle, a rear axle, an engine, an energy storage device, an electromechanical transmission, a fluid tank configured to store a fluid, a pump configured to provide the fluid from the fluid tank to a fluid outlet, and a power divider positioned between the engine, the pump, and the electromechanical transmission. The power divider includes a first interface coupled to the engine, a second interface coupled to the pump, and a third interface coupled to the electromechanical transmission. The electromechanical transmission is (i) selectively mechanically coupled to the engine by the power divider and (ii) electrically coupled to the energy storage device to facilitate driving at least one of the front axle or the rear axle. The pump is selectively mechanically coupled to the engine by the power divider to facilitate pumping the fluid to the fluid outlet.
US10981022B2
A smart respirator includes a main respirator-body including a first open end and a second open end. A diameter of the first open end is smaller than a diameter of the second open end. The smart respirator further includes a front respirator-body arranged at the first open end. The front respirator-body includes a filter sheet arranged inside the front respirator-body and configured to absorb pollutants in air entering the front respirator-body, an air sensor arranged inside the front respirator-body and configured to detect an air index of filtered air filtered by the filter sheet, and a flow sensor arranged inside the front respirator-body and configured to determine a total respiratory amount. The smart respirator also includes a fixation band arranged at the second open end.
US10981019B2
An apparatus includes: one or more input communicatively coupled to one or more medium storing current treatment plan data and a current image of a patient, the one or more input configured to obtain the current treatment plan data and the current image of the patient, wherein the current treatment plan data is for processing by a treatment machine; and a re-planning decision processor configured to determine a re-plan information based at least in part on the current treatment plan data, the current image, and a re-plan triggering model, the re-plan triggering model based on previous treatment plan data and previous image(s), wherein the re-plan information indicates a recommendation regarding treatment re-planning; wherein the re-planning decision processor is configured to output the re-plan information for reducing a burden, or for obviating a need, for a user of the apparatus to manually decide whether the treatment re-planning is desirable or not.
US10981012B2
According to one aspect of the present invention, there is provided an implantable medical device comprising: an implantable component, comprising an implantable memory module, configured to receive and store recipient-specific operating parameters in the implantable memory module, an external component, comprising an external memory module, configured to communicate with the implantable component to receive the recipient-specific operating parameters, and to configure the external component using the recipient-specific operating parameters, wherein the implantable medical device is configured to transfer the recipient-specific operating parameters upon operationally coupling the implantable component with the external component.
US10981011B2
An operating room cable assembly for electrically coupling at least one implantable electrical stimulation lead to a trial stimulator includes an elongated body; a trial stimulator connector disposed at one end of the elongated body; and a lead connector disposed at another end of the elongated body. The lead connector can include one or more buttons that can be pushed to load a lead into the lead connector and released to retain the lead. Alternatively, the lead connector can include a lever that can be operated to load the lead. A further alternative is a slider with a lead engagement element that can be slid between positions allowing loading of a lead and engagement of the lead. Other alternatives include a lead connector with doors that can swing open to allow loading of a lead or a collet/sleeve that can be tightened on the lead.
US10980999B2
Paddle leads and delivery tools, and associated systems and methods are disclosed. A representative system is for use with a signal delivery paddle that is elongated along a longitudinal axis, and has a paddle length and a first cross-sectional area distribution that includes a first maxima. The system comprises a delivery tool including a proximal handle and a distal connection portion positioned to removably couple to the signal delivery paddle. The paddle and the delivery tool together have a combined second cross-sectional area distribution along the length of the paddle, with a second maxima that is no greater than the first maxima.
US10980998B1
A method for implanting a wireless neural stimulator device, the method including: inserting a device through on a patient's skin on a posterior side of the patient's neck region, wherein the device includes a proximal end, a distal end, a first opening at the proximal end, a second opening at the distal end, and a lumen extending between the first opening and the second opening; after inserting the device through the patient's skin, advancing the distal end into the epidural space of the patient; inserting the wireless neural stimulator device through the first opening; advancing the wireless neural stimulator from the first opening through the lumen until the wireless neural stimulator exits the second opening and into the patient's epidural space; and advancing the wireless neural stimulator through the epidural space until a target site is reached.
US10980990B1
Certain exemplary embodiments can provide a system, machine, device, manufacture, circuit, composition of matter, and/or user interface adapted for and/or resulting from, and/or a method and/or machine-readable medium comprising machine-implementable instructions for, activities that can comprise and/or relate to, controlling delivery of a transdermally-delivered medication, certain embodiments including a flux controller.
US10980988B2
A stent has a center length section, two end sections, and an elastically deformable woven wire mesh, which enables the stent to expand from a small diameter to a larger diameter, with the diameter of the end sections being larger than in the center length section in the expanded state. The wire extends in a zig-zag manner from an outer end of one end section toward the outer end of the other end section, and back in a zig-zag manner to the one end section. The peripheral direction of the woven wire changes at the transition from an end section to the center length section, such that the wire intersects on the return path to the one end section in the center length section and overall forms an 8-shaped loop having two closed eyes, wherein a plurality of interconnected loops are arranged offset to each other over the circumference.
US10980987B2
A balloon catheter is disclosed, which is capable of improving accuracy of an inspection result of a tube wall of an elongated member constituting a catheter shaft and achieving further improved product quality through the inspection, and a method of manufacturing an elongated member for a balloon catheter, which is used for the balloon catheter. In an outer tube of a balloon catheter, distal from a proximal end of a guide wire lumen is formed of a transparent material. From a distal end toward a proximal end, an inner tube of the balloon catheter has at least a first region and a second region, the second region being a transparent region that is more transparent than the first region.
US10980984B2
A guidewire retention clip is provided to prevent the accidental, complete insertion of a guidewire into a patient during various procedures. As provided herein, the guidewire retention clip may include a body having a portion configured to hold a guidewire; a sensor associated with the body configured to detect movement of the guidewire to and from the body; and an audio and/or visual indicator arranged on the body, wherein the audio and/or visual indicator is triggered when the sensor detects movement of the guidewire. Methods of using the guidewire retention clip are also provided.
US10980982B2
An apparatus includes a catheter having a balloon including at least one first radiopaque marking. A guidewire guides the balloon to the treatment area, and includes at least one second radiopaque marking adapted for corresponding to the at least one first radiopaque marking of the balloon when positioned at the treatment area. Related aspects and methods are disclosed.
US10980975B2
Provided is a system for advancing an article along a path. The system may include a head member; a dispatching member, and an eversion sleeve configured with an inverted portion having a sleeve end configured to be fixed to the dispatching member. The system may also include an everting portion configured for articulating to the head member and an un-inverted portion configured to extend from the everting portion towards the dispatching member, at least partially within the inverted portion.
US10980973B2
Devices, systems, and methods for releasing a catheter from an implant may include a catheter comprising first and second elongate elements, first and second elongate element lumens, a tissue anchor lumen, apertures corresponding to each of the lumens, and retaining portions between adjacent apertures. The first elongate element may extend out of its lumen through the first elongate element aperture, across the retaining portion transversely with respect to a longitudinal axis, and towards the second elongate element aperture. The first elongate element may then extend into the second elongate element aperture, loop over the second elongate element, and extend back across the retaining portion and into the first elongate element lumen. In some instances, the second elongate element is retracted to uncouple the first and second elongate elements from each other and to open a channel for the release of tethered tissue anchors.
US10980968B2
This disclosure describes a micro-cutting machine for forming cuts in catheters, guidewires, and similar products. The micro-cutting machine can directly control the dimensions of the resultant beams being cut into these types of products, and can also capture images of each cut for feedback control and accuracy verification. The micro-cutting machine has two cutting blades each with cutting edges aligned with a vertical axis. Motors operate to move the cutting blades in a direction perpendicular to the longitudinal axis of the stock material being cut to form a pair of opposing grooves in the stock material with each cut.
US10980967B2
A respiratory assistance apparatus has a gases inlet configured to receive a supply of gases, a blower unit configured to generate a pressurised gases stream from the supply of gases; a humidification unit configured to heat and humidify the pressurised gases stream; and a gases outlet for the heated and humidified gases stream. A flow path for the gases stream extends through the respiratory device from the gases inlet through the blower unit and humidification unit to the gases outlet. A sensor assembly is provided in the flow path before the humidification unit. The sensor assembly has an ultrasound gas composition sensor system for sensing one or more gas concentrations within the gases stream.
US10980958B2
A sleep mask valve structure for treating a patient suffering from obstructive sleep apnea is provided. The valve structure includes a rigid valve housing comprising an inspiratory valve and an adjustable expiratory valve. The housing defines an outside mask side and an intra-mask side, and further defines an expiratory airflow conduit accommodating airflow from the intra-mask side to the outside mask side and an inspiratory airflow conduit accommodating airflow from the outside mask side to the intra-mask side. The expiratory airflow conduit includes at least two changes of direction, with each direction change greater than or equal to 75 degrees, and the inspiratory airflow conduit includes at least one change of direction greater than or equal to 75 degrees. The two paths share at least one change of direction.
US10980957B2
Apparatus and methods automate selection of patient interface(s) according to their size, such as with processing in a processor(s) or in a server(s). Image data captured by an image sensor may be received. The captured image data may contain facial feature(s) of an intended user of the patient interface. The facial features may be captured in association with a predetermined reference feature of known dimension(s). The user's facial feature(s) and the reference feature may be detected in the captured image data. Image pixel data of the image may be processed to measure an aspect of the detected facial feature(s) based on the reference feature. A patient interface size may be detected from standard patient interface sizes based on a comparison between the measured aspect of the facial feature(s) and a data record relating sizing information of the standard patient interface sizes and the measured aspect of the facial feature(s).
US10980953B2
An electronic cigarette includes a liquid supply including liquid material, a heater operable to heat the liquid material to a temperature sufficient to vaporize the liquid material and form an aerosol, a wick in communication with the liquid material and in communication with the heater such that the wick delivers the liquid material to the heater, at least one air inlet operable to deliver air to a central air passage upstream of the heater, and a mouth end insert having at least two diverging outlets. The electronic cigarette can also include an air flow diverter which directs incoming air away from a heating zone of the heater.
US10980947B2
Drive and dosing devices for injection devices are disclosed. An embodiment may include a threaded piston rod moveable in a dispensing direction for dispensing a product. A rotation member may be operatively connected to a stop limiter and threadably engaged with the piston rod. Rotation of the rotation member may cause the piston rod to move in the dispensing direction. An embodiment may include a dose knob rotatable for changing a dose. The device may further include a stop element threadably engaged with the piston rod and having a catch. The dose knob may be coupled with the stop element such that during increase of a dose, the stop element is screwed toward the distal end of the piston rod and the catch is moved towards the stop limiter. The stop element prevents increasing a dose when the catch abuts the stop limiter.
US10980940B2
A method may include receiving, from a volume meter at a pump configured to deliver medication to a patient, data indicative of a volume of a medication present in a syringe inserted in the pump. A first counter may be updated, based on the data, in response to the medication being delivered to the patient as a first dose type. A second counter may be updated, based on the data, in response to the medication being delivered to the patient as a second dose type. The volume of the medication delivered to the patient may be determined based on the first counter and/or the second counter. An electronic alert may be sent to a mobile device in response to one or more anomalies being present in the volume of the medication delivered to the patient. Related methods and articles of manufacture, including apparatuses and computer program products, are also disclosed.
US10980939B2
A device includes: a first member comprising a first-member-side power transmission part; and a second member comprising a second-member-side power transmission part configured to be attachable to and detachable from the first member, the second member being a part of a medicinal-liquid administering device. The first-member-side power transmission part and the second-member-side power transmission part are configured to be engaged with each other for administering a medicinal liquid into a living body. The second member is configured to open a housing covering the first-member-side power transmission part to engage the second-member-side power transmission part with the first-member-side power transmission part at a time of attaching the first member to the second member.
US10980936B2
An attachable needle assembly (102) for use on a medication delivery pen (104), the needle assembly (102) comprising a housing (1 10) enclosing a hub (106) having a communication needle (108) configured to engage the medication delivery pen (104) and pierce a reservoir septum of the medication delivery pen (104), a communication septum (172, 176) of the needle assembly (102) defining a septum chamber (180, 182) that is in fluid communication with the communication needle (108), a plurality of needles (118) disposed in the communication septum (172, 176), a follower ring (130) that determines which needle (124) of the plurality of needles (118) is to be selected, and a snap ring (136) that exposes the selected needle (124) and moves the selected needle (124) in fluid communication with the septum chamber (180, 182), wherein when the housing (110) is in a first position, the plurality of needles (118) is not exposed, and when the housing (110) is in a second position, the selected needle (124) is in fluid communication with the septum chamber (180, 182) and exposed for medicament delivery.
US10980930B2
The invention relates to fluid flow paths and fluid connectors for use with detachable containers that can be seated in an infusate caddy for use in a dialysis machine. The detachable containers can contain infusates or other solutes or materials such as disinfectants or cleaners, and can be conveniently seated in the infusate caddy. The detachable containers can be removed from the infusate caddy for restocking, cleaning, or resupply, as needed. The infusate caddy can be positioned or seated in a receiving compartment of a dialysis machine, and can also be removed, as needed. The fluid path and fluid connectors of the present invention provide the required fluid fittings, valve arrangements, pumps, and paddle assemblies for using the infusate caddy.
US10980924B2
A reduced-pressure canister includes a canister body having a fluid reservoir, an inlet for receiving fluids from a patient, and an integral hydrophobic filter formed within a side or top portion of the canister body. The integral hydrophobic filter has a plurality of pores in the canister body that are covered by a hydrophobic coating. Other canisters, methods, and systems are also presented.
US10980915B2
A patellar implant including a base portion formed of a porous metallic material, a polymeric portion formed of a polymeric material and attached to the base portion, and a membrane embedded between the base portion and the polymeric portion to provide a barrier between the porous metallic material and the polymer material.
US10980907B2
The present disclosure provides advantageous tray and bracket assembly that is configured and adapted to promote modularity and withstand the harsh environment of central sterile processing processes. Modular bracket assembly may be removed and relocated on tray without additional fasteners or components. Tray and bracket assembly may further provide identification features to correctly associate cataloged reusable medical devices to identified trays.
US10980902B2
Disclosed are compositions comprising polymeric nanoparticles and methods of using the same. The polymeric nanoparticles can be conjugated with a targeting ligand that is a substrate for a solid tumor-specific cell protein. The polymeric nanoparticles can also comprises an imaging compound and/or a therapeutic agent encapsulated in the hydrophobic interior of the nanoparticle. A cancer therapeutic composition comprising the nanoparticle is also disclosed. The disclosed nanoparticles can be used to target and deliver imaging and/or therapeutic compounds to cancer cells, thereby identifying and/or treating a solid tumor cell target. Methods for treating cancer, such as lung cancer, using the polymeric nanoparticles are also disclosed.
US10980895B2
What is described is a compound of formula I consisting of a compound in which R1 is a branched chain alkyl consisting of 10 to 31 carbons; R2 is a linear alkyl, alkenyl, or alkynyl consisting of 2 to 20 carbons; L1 and L2 are the same or different, each a linear alkylene or alkenylene consisting of 2 to 20 carbons; X1 is S or O; R3 is a linear or branched alkylene consisting of 1 to 6 carbons; and R4 and R5 are the same or different, each a hydrogen or a linear or branched alkyl consisting of 1 to 6 carbons; or a pharmaceutically acceptable salt thereof.
US10980892B2
The present invention features a method of treating leptomeningeal carcinomatosis in a subject using a peptide-therapeutic conjugate as exemplified by the agent ANG1005.
US10980891B2
The present technology relates generally to oligolactic acid conjugates of paclitaxel, rapamycin, selumetinib, and other anticancer agents, micelle compositions containing such conjugates and methods of preparing and using such compositions to treat various cancers. Specifically, there are provided oligolactic acid conjugates wherein the oligolactic acid comprises 2 to 24 lactic acid subunits and is attached through an ester linkage to the oxygen of the 7-hydroxyl of the paclitaxel or paclitaxel derivative, the 40-hydroxyl of the rapamycin or rapamycin derivative, and the 2′-hydroxyl of the selumetinib or selumetinib derivative. Compositions comprising water and a micelle comprising a polylactic acid-containing polymer and the oligolactic acid conjugate may be readily prepared. Methods of inhibiting or killing cancer cells and treating paclitaxel, rapamycin, and/or selumetinib cancers are also provided.
US10980887B2
The present invention relates to a method for providing an embedded mammalian cell, comprising the steps of providing an alginate sulfate in aqueous solution; reacting the alginate sulfate to form a hydrogel in a gelation step, providing a precursor cell, and embedding the precursor cell in the sulfated alginate hydrogel in an embedding step, thus yielding an sulfated alginate hydrogel embedded cell. The invention further relates to sulfated alginate hydrogels, and cellular grafts comprising a mammalian cell embedded in sulfated alginate hydrogel.
US10980884B2
The invention provides stabilized aqueous pharmaceutical etanercept compositions suitable for long-term storage of etanercept, methods of manufacture of these compositions, methods of administration, and kits containing same.
US10980877B2
The present invention concerns methods and compositions for evoking protective immune responses against pathogen infection or cancer. In certain embodiments, the methods and compositions comprise a lymphangiogenesis inducer and an antigen.
US10980875B2
The present invention relates to particles comprising RNA, in which the RNA is associated with a cationic polymer or lipid or with both a cationic polymer and lipid, wherein the RNA comprises a cytotoxic nucleotide or cytotoxic nucleotide analog and/or the RNA is covalently attached to a cytotoxin, pharmaceutical compositions containing said particles and pharmaceutical uses of the particles and pharmaceutical compositions. The particles of the present invention are particularly useful as an immunostimulating medicament capable to block proliferation or induce death in dividing cells such as tumor cells.
US10980873B2
The invention relates to a genetically modified infectious measles virus derived from a live-attenuated measles virus strain, in which the gene encoding the viral accessory C protein has been knocked out (MV-deltaC). It concerns in particular the use of said genetically modified infectious MV-deltaC in the treatment of malignant tumour or cancer conditions, and for the preparation of agents or compositions for such treatment.
US10980869B2
The present invention includes compositions and methods for the expression, secretion and use of novel compositions for use as, e.g., vaccines and antigen delivery vectors, to delivery antigens to antigen presenting cells. In one embodiment, the vector is an anti-CD40 antibody, or fragments thereof, and one or more antigenic peptides linked to the anti-CD40 antibody or fragments thereof, including humanized antibodies.
US10980868B2
The present invention relates to an attenuated strain of Salmonella comprising at least one copy of a DNA molecule comprising an expression cassette encoding a VEGF receptor protein for use in cancer immunotherapy, wherein the cancer is characterized by VEGF receptor protein expressing cancer cells. The present invention further relates to an attenuated strain of Salmonella comprising at least one copy of a DNA molecule comprising an expression cassette encoding a VEGF receptor protein for use in cancer immunotherapy, wherein the cancer is characterized by VEGF receptor protein expressing cancer cells, and wherein the cancer is selected from the group consisting of glioblastoma, carcinoid cancer, kidney cancer, particularly renal cell carcinoma, thyroid cancer, lung cancer, particularly Non-Small Cell Lung Cancer (NSCLC), breast cancer, ovarian cancer, prostate cancer, gastrointestinal cancer, particularly colorectal cancer, more particularly colon cancer, and skin cancer, particularly melanoma. The present invention further relates to an attenuated strain of Salmonella comprising at least one copy of a DNA molecule comprising an expression cassette encoding a VEGF receptor protein for use in cancer immunotherapy in a patient comprising at least one VEGF receptor protein expressing cancer cell.
US10980867B2
The invention is directed to T cell epitopes wherein said epitopes comprises a peptide or polypeptide chain comprising at least a portion of an immunoglobulin constant or variable region. The invention also relates to methods of using and methods of making the epitopes of the invention.
US10980864B2
It is disclosed herein that microperoxidases are capable of binding carbon monoxide (CO) with high affinity and displacing CO from hemoglobin, thereby acting as CO scavengers. The present disclosure provides methods of treating carboxyhemoglobinemia (or CO poisoning) in a subject by administering a therapeutically amount of an isolated or recombinant microperoxidase. Methods of removing CO from hemoglobin in blood or tissue by administering a therapeutically amount of an isolated or recombinant microperoxidase are also described. Methods of determining the effectiveness of a microperoxidase for removing CO from hemoglobin are further described.
US10980861B2
The present invention relates to the use of liver-selective glucokinase activators and a GLP1 analog in restoring insulin sensitivity and treating type II diabetes, including reducing body weight in subjects undergoing type II diabetes treatment.
US10980860B2
The present invention relates to a polymeric prodrug for use in the treatment, prevention and/or diagnosis a disease of the joint and pharmaceutical compositions and medical devices comprising said polymeric prodrugs.
US10980853B2
The present invention provides a process for the preparation of a Crassocephalum crepidioides extract, and the extract prepared thereby. The present invention further relates to a pharmaceutical composition/combination comprising the Crassocephalum crepidioides extract. The use of the extract and the composition/combination comprising the extract in the prevention or treatment of cancer is also provided.
US10980850B2
Described herein is use of a Caspase activator and an oncolytic virus in the preparation of an anti-tumor drug. As described, Caspase activator can enhance the anti-tumor effect of oncolytic virus, and the combination of Caspase activator and oncolytic virus produces a significant synergistic anti-tumor effect, and demonstrates an effective therapy for the treatment of tumors that are less sensitive to other pharmaceutical treatments.
US10980841B2
Embodiments of the invention stimulate three levels of beta cell physiology: (i) glucose metabolism, (ii) membrane receptor function, and (iii) transcriptional factors that result in the in vivo formation of beta cells in the pancreas for the purpose of treating diabetes.
US10980836B1
The present disclosure provides compositions and methods for making and using engineered killer phagocytic cells for immunotherapy in cancer or infection by expressing a chimeric antigen receptor having an enhanced phagocytic activity, the chimeric receptor is encoded by a recombinant nucleic acid.
US10980835B2
The present invention relates to the treatment of Pin1-associated disorders (e.g., disorders characterized by elevated Pin1 activity) with arsenic trioxide, optionally in combination with a retinoic acid compound. Pin1-associated disorders may include, for example, proliferative disorders (e.g., cancers), inflammatory conditions, and autoimmune disorders associated with aberrant levels of Pin1 activity.
US10980828B2
Described are methods for using cyclodextrin to treat, inhibit, prevent, ameliorate, or cure diabetes or conditions relating to diabetes.
US10980826B2
The present application provides a pharmaceutical composition for treating and/or preventing a cancer comprising, as an active ingredient, a polynucleotide derived from miRNA associated with the cancer, a combination drug of the pharmaceutical composition and another antitumor agent, and a method for treating or preventing a cancer in a subject having the cancer using the pharmaceutical composition or the combination drug.
US10980823B2
The present invention relates to a foodstuff comprising feather hydrolysate for use in improving performance during exercise and/or improving recovery after exercise in a dog. It also relates to a method of improving the performance in a dog during exercise and/or improving recovery after exercise, the method comprising administering to a dog a foodstuff which comprises feather hydrolysate.
US10980822B2
Provided is a pharmaceutical composition comprising an antidiabetic agent and an antihypertensive agent as active ingredients.
US10980821B2
Tri-phenyl-phosphonium (TPP) is a non-toxic chemical moiety that functionally behaves as a mitochondrial targeting signaling in living cells. TPP-related compounds may be utilized to target mitochondria in cancer stem cells (CSCs), and may be used for treating and/or preventing tumor recurrence, metastasis, drug resistance, and/or radiotherapy resistance, as well as for anti-cancer therapies. Various TPP-related compounds validated for oxygen consumption inhibition (OCR), were non-toxic, and had little or no effect on ATP production in normal human fibroblasts. Yet these compounds selectively target adherent “bulk” cancer cells. These compounds also inhibit the propagation of CSCs in suspension. TPP-related compounds provide a novel chemical strategy for effectively targeting both i) “bulk” cancer cells and ii) CSCs, while specifically minimizing or avoiding off-target side-effects in normal cells, among other useful therapies.
US10980819B2
The present disclosure provides high concentration formulations of cortexolone-17α-propionate suitable for treating alopecia.
US10980796B2
The present invention relates to a drug delivery system having a double core-shell structure and, specifically, to a double nano-drug delivery system having an inner core-shell containing a poorly soluble camptothecin compound and a water-soluble camptothecin compound inside and an amphiphilic polymer shell, and to a manufacturing method therefor. The double core-shell structured particles manufactured by the present invention form very stable particles and show a mono-distribution of particles before and after freeze-drying. The particles of the present invention show excellent results compared with existing monolayer micelles in animal efficacy tests and pharmacokinetic tests, and do not use a surfactant causing hypersensitivity, and thus the use of the particles of the present invention can provide a pharmaceutical composition or a drug delivery system platform, which are safe for the human body.
US10980788B2
Provided are methods and compositions for treating cancers in patients carrying an IDH1 mutation using an inhibitor of a mutant IDH1 enzyme.
US10980767B2
Provided are compounds and methods for treating neurodegenerative diseases and conditions, such as multiple sclerosis, using an estrogen receptor-β ligand (ERβ ligand).
US10980763B2
Provided herein is technology relating to lipid compositions containing bioactive fatty acids and particularly, but not exclusively, to compositions and methods related to the production and use of structured lipid compositions containing sciadonic and/or pinoleic acid alone or in combination with other bioactive fatty acids including, but not limited to, eicosapentaenoic acid, docosahexaenoic acid, conjugated linoleic acid, and non-β-oxidizable fatty acid analogues such as tetradecylthioacetic acid.
US10980754B2
The present disclosure provides compounds of the formula (I), (II), (III), wherein the variables are as defined herein for use in the treatment of fungal infections. In some embodiments, the fungal infection is an infection of Cryptococcus neojormans fungus. Also provided herein are compositions comprising a compound of formula I, II, or III and a second anti-fungal agent.
US10980753B2
The present invention relates to transdermal therapeutic systems (TTS) for the transdermal administration of asenapine comprising a self-adhesive layer structure containing a therapeutically effective amount of asenapine, such asenapine TTS for use in a method of treatment, processes of manufacture of such TTS as well as asenapine and transdermal therapeutic systems containing asenapine for use in a method of treatment and to a method of treating a human patient by transdermal administration of asenapine.
US10980751B2
The invention refers to a pharmaceutical or nutraceutical composition comprising a core a) comprising an active ingredient and a water-insoluble polymer, a coating layer b) above the core a) comprising a salt of an alginic acid, and a coating layer c) above the coating layer b) comprising an anionic (meth)acrylate copolymer polymerized from a (meth)acrylate monomer mixture comprising 5-75% by weight in relation to the total weight of the (meth)acrylate monomer mixture of (meth)acrylate monomers with an anionic group, wherein the amount of the water-insoluble polymer in the core a) is 2 to 20% by weight in relation to the weight of the core a) and the amount of the salt of an alginic acid in the coating layer b) is 5 to 85% by weight in relation to the weight of the core a) and the amount of the anionic (meth)acrylate copolymer in the coating layer c) is 10 to 75% by weight in relation to the weight of the core a) and to the coating layer b).
US10980749B2
Embodiments of the invention provide swallowable devices, preparations and methods for delivering drugs and other therapeutic agents within the GI tract. Many embodiments provide a swallowable device for delivering the agents. Particular embodiments provide a swallowable device such as a capsule for delivering drugs into the intestinal wall or other GI lumen. Embodiments also provide various drug preparations that are configured to be contained within the capsule, advanced from the capsule into the intestinal wall and degrade to release the drug into the bloodstream to produce a therapeutic effect. The preparation can be operably coupled to delivery means having a first configuration where the preparation is contained in the capsule and a second configuration where the preparation is advanced out of the capsule into the intestinal wall. Embodiments of the invention are particularly useful for the delivery of drugs which are poorly absorbed, tolerated and/or degraded within the GI tract.
US10980746B2
The present invention features compositions comprising a plurality of therapeutic agents wherein the presence of one therapeutic agent enhances the properties of at least one other therapeutic agent. In one embodiment, the therapeutic agents are cystic fibrosis transmembrane conductance regulators (CFTR) such as a CFTR corrector or CFTR potentiator for the treatment of CFTR mediated diseases such as cystic fibrosis. Methods and kits thereof are also disclosed.
US10980712B2
Radically polymerizable dental material, which contains at least one encapsulated photochromic colorant.
US10980703B2
Disclosed embodiments provide an improved stimulation device. Embodiments of the improved stimulation device include a cup and a driver. The cup has a cavity surrounded by a rim. In use, a user positions the rim such that an opening to the cavity is over an area to be stimulated (for example, the clitoris). A sealed-, or substantially-sealed, chamber is formed by the cavity walls and the user's skin (surrounding the clitoris). A pressure field is generated in the chamber without generating a pressure below a reference pressure, which is gauge pressure reading of zero. In some embodiments, this is achieved by a driver configured to vary a volume of the cavity in such a way that the varied volume is not larger than an initial volume. In some embodiments, the stimulation device is a sex toy. In some embodiments, the stimulation device is a medical device.
US10980698B2
The current disclosure is directed to embodiments of an apparatus, method and systems for collapsing/lowering an exoskeleton device including at least one motor and at least one component. In some embodiments, the device is configured to be moved by the at least one motor. When at least one of any of a plurality of faults including power faults such as a low power fault and a power failure fault, electrical faults, software faults and mechanical faults, is detected in the powering the exoskeleton device, one or more components of the device may be decelerated via the at least one motor.
US10980696B2
Various implementations include a device for assisting with and controlling stretching of a limb of a patient. The device includes a limb support for receiving the limb, a base, and a coupling that rotatably couples the limb support and the base. The coupling allows the limb support to rotate through various axes of rotation individually, depending on the range of motion expected for the limb. For example, for a device designed for the foot, the coupling allows a foot support to rotate about a first axis, a second axis, and a third axis, wherein the three axes are orthogonal to each other. In other implementations, the device may be designed for other portions of limbs, such as the hand, the forearm, the upper arm, the lower leg, and the upper leg.
US10980694B2
A patient securing overlay is provided that includes a sheet of fabric for supporting a patient's torso on a surgical table. The sheet of fabric has an upper surface configured to face the patient and a lower surface configured to face a surgical table mattress or underbody support. The sheet of fabric includes friction enhancing elements applied to at least a portion of the upper surface thereof. The sheet of fabric can include an extension at a foot end of the sheet of fabric that provides material to be tucked under a foot end of the surgical table mattress or underbody support for securing the foot end of the sheet of fabric to the surgical table mattress or underbody support. The extension can include one or more friction enhancing elements.
US10980687B2
A patient support apparatus comprises a base and a support structure coupled to the base and being configured to support a patient. The apparatus also comprises a panel having a surface and being physically adapted to vibrate at one or more frequencies, a controller configured to generate an electrical signal, and a vibrational exciter. The vibrational exciter comprises a surface coupled to the surface of the panel and being configured to receive the electrical signal from the controller and to convert the electrical signal into vibrational energy. The surface of the vibrational exciter is configured to transfer the vibrational energy to the surface of the panel to vibrate the panel at the one or more frequencies.
US10980683B2
An autonomous stretcher intended for patients with reduced mobility, particularly quadriplegic and paraplegic, is adjustable in height and transformable between a horizontal position in the manner of a bed for housing the patient lying down and a staggered position in the manner of a chair. It incorporates transport litters destined for supporting the patient, endowed with movement in a transverse direction to the supports in both directions of movement: towards the exterior of the stretcher to remove the patient from the stretcher, for example towards a bed or a wheelchair and towards the interior of the stretcher to accommodate the patient therein. It makes it possible to modify its longitudinal or transverse orientation with respect to the frame and enables the patient to satisfy his or her physiological evacuation needs through the stretcher itself in a sitting position.
US10980659B2
A head positioning aid includes at least one head positioning assistor and at least one securing member. Some head positioning aids include positioning members secured to a headwear member. The positioning members maintain an infant's head in midline. An optional cheek flap protects the skin on the face. An optional support member supports the neck and an open airway. Size adjustment members may also be used to secure and orient tubing for a nasal cannula.
US10980657B2
A spinal orthosis includes posterior panels arranged with a flat spinal curvature to create a reverse three-point pressure system to the spine. The reverse three-point pressure system relieves pressure on the posterior side of the vertebrae beneficial for certain indications. Various arrangements allow for securing the posterior panel to the spinal orthosis. The spinal orthosis includes a belt member length adjustment system including belt members having end portions reducible in length and a belt panel adapted to secure to the end portion of the belt member reduced in length to form at least in part a belt circumference of the spinal orthosis.
US10980656B2
A removable and replaceable hip orthotic that includes a back panel formed from a rigid material that supports a patient's lumbar area; a front panel formed from the rigid material that supports the patient's abdomen area and is hinged to the back panel to allow application and removal of the orthotic to the patient; a leg support that extends from the back support that includes a space that allows a patient's leg to pass through into the leg support; and straps to secure the back panel to the front panel and the leg into the leg support. The back panel includes a pair of windows with a trochanter pad movably disposed within the windows. An adjustment mechanism selectively moves the trochanter pads relative to the greater trochanter regions of the hips of the patient to apply pressure to the hip joint to prevent dislocation of the femoral head.
US10980646B2
A measurement device is provided for measuring a resected femoral head. The device comprises a base (102) with a support rod (104) extending transversely from the base and extending in a direction corresponding to a height of a resected femoral head. A femoral head support (108) is attached to a base proximate an end of the support rod (104) for supporting a severed end of a femoral head at a selected incline between about 30° and 60° relative to the base such that a height of the resected femoral head extends in the general direction of the support rod. A transverse height indicating arm (120) is adjustable up the height of the support rod (104) so as to measure the height of a resected femoral head (106) positioned on the femoral head support in use. The transverse height indicating arm (120) may carry adjustable offset indicating arm (122).
US10980643B2
A joint implant system adapted for use in joint surgeries. Among other things, the joint implant has an anterior cutting edge and a rotatable cutter supported by a rotatable shaft.
US10980642B2
An expandable fusion device is capable of being installed inside an intervertebral disc space to maintain normal disc spacing and restore spinal stability, thereby facilitating an intervertebral fusion. The fusion device may include a body portion, a first endplate, and a second endplate, the first and second endplates capable of being moved in a direction away from the body portion into an expanded configuration or capable of being moved towards the body portion into an unexpanded configuration. The fusion device is capable of being deployed and installed in both configurations.
US10980639B2
The invention pertains to implants that facilitate tissue expansion while not substantially inhibiting normal anatomical movement. The implants may be made of different materials or made in different configurations such that such that a measured property at a first location on said implant is different than said same measured property at a second location on said implant. In one particular embodiment the implants may be a cosmetic penile implant.
US10980625B2
The invention generally relates to devices for fastening a hernia mesh. The invention provides a surgical fastening device that includes a shaft with a fastener carrier disposed at least partially within the shaft, in which the carrier is configured to accept fasteners of a plurality of different sizes. Different sized fasteners can be preloaded in interchangeable carriers or even mixed together within a carrier in the fastening device. The device can deliver the fasteners to different depths in a patient's tissue.
US10980616B2
A series of appliances including a first shell and a second shell can be designed to incrementally implement a treatment plan. The first and second shells can have cavities designed to receive teeth of a jaw. A first number of bite adjustment structures can be formed of a same material as the first shell and extend from the first cavities and be designed to interface with teeth of a second jaw. The first number of bite adjustment structures can have a first shape and location. A second number of bite adjustment structures can be formed of a same material as the second shell and extend from the second cavities and be designed to interface with teeth of the second jaw. The second number of bite adjustment structures can have a second shape and location, different than the first shape and location.
US10980610B2
Systems, methods, and computer-readable media are provided for robotic surgical device control. A system is provided including a robotic arm, an autosteroscopic display, a user image capture device, an image processor, and a controller. The robotic arm is coupled to a patient image capture device. The autostereoscopic display is configured to display an image of a surgical site obtained from the patient image capture device. The image processor configured to identify a location of at least part of a user in an image obtained from the user image capture device. The controller is configured to, in a first mode, adjust a three dimensional aspect of the image displayed on autostereoscopic display based on the identified location, and, in a second mode, move the robotic arm or instrument based on a relationship between the identified location and the surgical site image.
US10980609B2
A re-usable medical procedure power tool includes a subframe having a handle portion connected to a tool attachment portion and a power source portion. A removable, single use, contamination-blocking cover substantially covers the sub frame of the tool. At least the handle portion of the cover includes a flexible portion providing a tactile feel portion for a user. The tactile feel portion is movable sufficient to move an associated trigger attached to the subframe.
US10980608B2
Generally, a sterile adapter for use in robotic surgery may include a frame configured to be interposed between a tool driver and a surgical tool, a plate assembly coupled to the frame, and at least one rotatable coupler supported by the plate assembly and configured to communicate torque from an output drive of the tool driver to an input drive of the surgical tool.
US10980607B2
A steerable introduction system for deploying an interventional tool (e.g., a replacement valve) within an anatomical object (e.g. a heart). The steerable introduction system employs a steerable introducer (20) including an end-effector for positioning the interventional tool within the anatomical object (e.g., the end-effector passively guides or actively steers the interventional tool within the anatomical object). The steerable introduction system further employs an image guidance workstation (120) controlling an actuation of a translation, a pivoting and/or a rotation of the end-effector within the anatomical object responsive to surgical image data illustrative of a position of the end-effector within the anatomical object (e.g., ultrasound or X-ray image data illustrative of a surgical position of the end-effector within a heart). The motion actuation by the image guidance workstation (120) of the end-effector facilitates a coaxial alignment and/or a coplanar alignment of the interventional tool and a structure of the anatomical object (e.g., a diseased aortic valve of a heart).
US10980593B2
Concepts presented herein relate to an interface module that can be electrically coupled to an electrical stimulation generator, a radio frequency generator and an instrument. A selection module is coupled to the interface module and operates in a first mode to deliver electrical stimulation signals from the electrical stimulation generator to the instrument and in a second mode to deliver radio frequency signals from the radio frequency generator to the instrument.
US10980587B2
A adaptor is used with a driver, a drill, and a cannula to facilitate removal of material from bone and placement of the cannula in the bone. The adaptor includes an end portion provided at a proximal first end that is configured to engage a portion of the drill; a body portion attached to the end portion and extending from the end portion toward a distal second end; a head portion provided at the distal second end and attached to the body portion; and a passageway for receiving the drill that extends through the adaptor. Furthermore, the head portion includes a distal surface and at least one coupler provided on or adjacent the distal surface for releasably engaging, the cannula.
US10980585B2
A method for fixating or stabilizing a subject's mandible and maxilla includes providing multiple bone fasteners, providing two arch bars, attaching a first grouping of the bone fasteners to the subject's mandible, then securing the first arch bar to the first grouping of bone fasteners, attaching a second grouping of the bone fasteners to the subject's maxilla, then securing the second arch bar to the second grouping of bone fasteners, and then fastening the first arch bar to the second arch bar.
US10980584B2
A modular bone fixation linkage includes a plurality of interconnected links that can angulate with respect to an adjacent one of the links in-plane or out-of-plane. The links can further include fixation holes that are configured to receive fixation members that secure the links to an underlying anatomical structure.
US10980564B2
An ultrasonic surgical instrument has a shaft and a probe head, the shaft and the probe head have a lumen or channel and a longitudinal axis and the probe head having a distal end face. The probe head has at least one operative surface engageable with organic tissues for the application of ultrasonic vibratory energy to the tissues. The end face is oriented at least partially transversely to the axis. The lumen or channel has a first outlet opening in the end face and at least one second outlet opening in a lateral surface of either the shaft or the probe head at a position spaced from the end face. The probe head has a plurality of teeth extending laterally from the end face, in two rows on opposing side of the end face.
US10980561B1
A rotatory resectoscope is disclosed with a novel mechanism for endoscopic resection. Resection is performed by a rotary motion instead of the conventional linear motion. A novel resection loop and working element for controlling the movement of the resection loop allow the resection loop to move in clockwise and counterclockwise rotation. Embodiments include both monopolar and bipolar diathermy resectoscopes.
US10980548B2
Tools and methods for expanding a precursor hole in a host material to receive a fixture. The precursor hole is enlarged by a rotary tool having helical flutes and interposed lands. The flutes have a negative rake angle. The lands each have a working edge that cuts the host material when the tool is rotated in a cutting direction, and that condenses the host material when the tool is rotated in a densifying direction. The body of the rotary tool has a stopper section that plugs the hole when a certain depth is reached. When the tool is used with a copious wash of irrigating fluid at or below the necessary depth, hydraulic pressure builds inside the precursor hole. The hydraulic pressure can be advantageously exploited in cutting mode to autograft a slurry of host material particles into the sidewalls of the hole and create an incipient densifying crust.
US10980543B2
A stapler according to the present invention is provided with: a holder provided with an accommodating portion that accommodates a plurality of staples with tips thereof, which pass through a suturing target, directed in one direction; a plurality of pushers that push out the staples accommodated in the accommodating portion in accordance with a plurality of groups thereof; an anvil that presses and deforms the staples pushed out from the accommodating portion by the pushers; driving-force transmitting mechanisms that are respectively connected to the individual pushers, in which the movement thereof in directions other than the directions in which the staples are pushed out is restricted at the individual connection portions, and that transmit driving forces that move the individual pushers toward the anvil.
US10980537B2
A motorized surgical instrument is disclosed. The surgical instrument includes a displacement member configured to translate over a plurality of predefined zones. A motor comprising a shaft is coupled to the displacement member. A control circuit is coupled to the motor. A position sensor is coupled to the control circuit to monitor the rotation of the shaft. A timer circuit is coupled to the control circuit. The control circuit is configured to receive rotations of the shaft in a current zone defined by a set rotation interval, measure time at a set position of the rotation interval, wherein the measured time is defined as the time taken by the displacement member to traverse the rotation interval based on a predetermined number of shaft rotations, and set a command velocity of the displacement member for a subsequent zone based on the measured time in the current predefined zone.
US10980516B2
According to one embodiment, an ultrasonic diagnostic apparatus comprises plurality of processing circuitry and control circuitry. The control circuitry comprises a plurality of processing circuitry interfaces, a plurality of internal memories, and a control information interface. The plurality of processing circuitry interfaces respectively connected to the plurality of processing circuitry. The plurality of internal memory respectively connected to the plurality of processing circuitry interfaces. The control information interface configured to transfer control information associated with at least reception of the ultrasonic wave to at least one of the plurality of internal memories.
US10980505B2
A system and method for air calibration in a Computed Tomography (CT) imaging system are provided. A first set of data associated with air in a scanning area may be obtained. A second set of data associated with an object in the scanning area may be obtained. The second set of data based on the first set of data may be calibrated, and a set of reference values generated by a neural network model may be used to perform the calibration. A third set of data based on the calibration of the second set of data may be generated. Based on the third set of data, a CT image of the object may be generated.
US10980503B2
An X-ray fluoroscopy imaging apparatus that corrects to precisely remove a banding artifact in an X-ray image, includes an image processing unit that corrects an X-ray image by processing the image to remove the banding artifact (AF) from the X-ray image based on the average difference brightness value (DLa) relative to a plurality of pixels included in an array in an artifact extending direction (A-direction).
US10980494B2
Systems and related methods for stationary digital chest tomosynthesis (s-DCT) imaging are disclosed. In some aspects, systems include a stationary x-ray source array with an array of x-ray pixels configured to generate x-ray beams at different viewing angles relative to a subject to be imaged that is stationary, a stationary area x-ray detector configured to record x-ray projection images of the subject, a physiological gating apparatus for monitoring at least one physiological signal of the subject and defining a physiological phase and a time window based on the at least one physiological signal, and a computing platform configured to activate the x-ray pixels based on the physiological phase and the time window and upon receipt of the at least one physiological signal from the physiological gating apparatus in order to synchronize x-ray exposure with the at least one physiological signal of the subject.
US10980489B2
In a method and a device for quantification of a respiratory sinus arrhythmia, a heart-rate curve is measured first and then the time elapsed between two heartbeats is determined and quantified by an analysis in the phase domain. A more informative quantification is obtained when suitable coefficients are used or the heart-rate curve is interpolated and/or detrended for the quantification.
US10980480B2
Systems, devices, and methods are provided to assess connection quality between the electrodes of a bioelectrical signal measurement and/or electrical stimulation device and the tissue, typically skin, of the subject. A test signal is provided to a first electrode, voltage differences between the first electrode and additional electrodes are determined, an impedance of the first electrode is determined based on the voltages differences, and the determined impedance indicates connection quality. This process is typically repeated for all of the electrodes to determine connection quality. The user or subject can be alerted if the connection quality is poor, and the bioelectrical signal that is recorded can be provided with data points indicating connection quality during the signal recording.
US10980475B2
A method including a step of preparing a sampling apparatus for use. The sampling apparatus includes a tubular member having an opening on a distal end thereof. An orientation of the distal end of the tubular member is shapeable. The distal end is substantially rigid so as to maintain a manipulated shape after a direct application of a threshold level of force on the distal end of the tubular member. The tubular member also includes a joint member disposed on a proximal end of the tubular member. The joint member is configured to connect the tubular member to a systemic biomarker sampling device.
US10980467B2
An apparatus, module, methods and systems for automated, standardized assessment and analysis of a human olfactory system's odor detection ability as an indicator or predictor of cognitive impairment or change in cognitive health, and other health conditions such as diabetes. Notably, the present invention is operable for use across all age groups of humans and provides quantitative detection and analysis of a human olfactory system's detection ability compared to a relevant demographic population.
US10980453B2
Methods and apparatus are provided for communication among display devices and sensor electronics unit in an analyte monitoring system. The analyte monitoring system may include a sensor that is configured to perform measurements indicative of analyte levels. The sensor may be communicatively coupled to the sensor electronics unit. The sensor electronics unit may be configured to transmit data indicative of analyte levels to the display devices using one or more communication protocols. Furthermore, the sensor electronics unit may be configured to operate in multiple modes, and switch between the modes in response to commands received from the display devices. Related systems, methods, and articles of manufacture are also described.
US10980451B2
Methods and apparatus are provided for communication among display devices and sensor electronics unit in an analyte monitoring system. The analyte monitoring system may include a sensor that is configured to perform measurements indicative of analyte levels. The sensor may be communicatively coupled to the sensor electronics unit. The sensor electronics unit may be configured to transmit data indicative of analyte levels to the display devices using one or more communication protocols. Furthermore, the sensor electronics unit may be configured to operate in multiple modes, and switch between the modes in response to commands received from the display devices. Related systems, methods, and articles of manufacture are also described.
US10980447B2
Body joint tracking is applied in various industries and medical field. In body joint tracking, marker less devices plays an important role. However, the marker less devices are facing some challenges in providing optimal tracking due to occlusion, ambiguity, lighting conditions, dynamic objects etc. System and method of the present disclosure provides an optimized body joint tracking. Here, motion data pertaining to a first set of motion frames from a motion sensor are received. Further, the motion data are processed to obtain a plurality of 3 dimensional cylindrical models. Here, every cylindrical model among the plurality of 3 dimensional cylindrical model represents a body segment. The coefficients associated with the plurality of 3 dimensional cylindrical models are initialized to obtain a set of initialized cylindrical models. A set of dynamic coefficients associated with the initialized cylindrical models are utilized to track joint motion trajectories of a set of subsequent frames.
US10980446B2
The present invention relates to distinguishing different sedentary states of a subject. A sedentary state can refer to standing, sitting and/or lying. An apparatus for determining a sedentary state of a subject is presented that comprises a sensor interface for obtaining a movement signal indicative of a movement of the subject; an extraction unit for extracting a signal feature indicative of postural control oscillations of the subject from the movement signal, wherein the signal feature indicative of postural control oscillations is indicative of center of mass motion oscillations for preventing the subject from falling; and a classifier for classifying a sedentary state of the subject based on the signal feature indicative of postural control oscillations of the subject. Further, a corresponding method, computer program and system are presented.