US12130210B1
The present invention provides a geotechnical centrifuge platform-based earthquake fault simulation system, involving the field of earthquake disaster simulation technology. A bottom support system of the geotechnical centrifuge platform-based earthquake fault simulation system is used to support a horizontal actuation system and simulate earthquake faults and site covering layers. The horizontal actuation system is used to apply horizontal thrusts to simulated earthquake faults and site covering layers. The simulated earthquake faults are used to fill fault test blocks to simulate bedrock layers of earthquake faults and the site covering layers are used to fill sand layer materials onto surfaces of the simulated earthquake faults to simulate soil layers of the earthquake faults.
US12130208B2
When producing a high-pressure hydraulic line, a connection fitting is attached to a multi-layer high-pressure hose having a reinforcing layer. A portion of a reinforced high-pressure hose and a connection fitting to be joined to it are provided. The connection fitting is placed onto the end portion of the high-pressure hose and a joining operation is carried out to form a sealed connection. The quality of the connection is determined by applying an electrical test signal to at least one connection of a testing arrangement having two connections. A first connection is electrically and/or magnetically coupled to the connection fitting and a second connection is contactlessly electrically and/or magnetically coupled to a reinforcing layer of the high-pressure hose. An electrical response signal is detected and the response signal is compared with a setpoint-value range stored in a memory of the testing arrangement.
US12130201B2
A pressure detection device 1 includes: an enclosure assembly configured to be mounted in a communication hole in an internal combustion engine; a diaphragm head 32 provided at one end of the enclosure assembly and configured to receive pressure of combustion gas from the internal combustion engine; and a buffer member 80 located at the diaphragm head 32 and configured to supply the combustion gas to the diaphragm head 32 while reducing the temperature of the combustion gas. Female threads formed on a first buffer member 81 of the buffer member 80 and male threads formed on a second buffer member 82 of the buffer member 80 are configured to threadably engage each other.
US12130183B2
A fire measuring device for electric vehicles in a garage includes a fire parameter acquisition device for collecting fire parameters during the fire evolution process of electric vehicles in the garage, a fire monitoring device for dynamically recording the combustion process, a computer, a charging pile, and a water gun fire extinguishing mechanism. The fire monitoring device communicates with the computer. The fire parameters include heat release rate, temperature, radiation, released gas, and electric vehicle mass change. The invention adopts a fire measuring device for electric vehicles in the garage with the above structure. By measuring the parameters such as heat release rate, temperature, radiation, and released gas type during the firing process, the firing mechanism of the electric vehicle stored in the garage is further analyzed and studied to provide basic data for the technical development of electric vehicle fire safety and provide experimental guidance for personnel training.
US12130177B2
An image processing device includes a light receiving element, a light emitting element, a battery, a power source circuit electrically coupled to the battery, a first substrate provided with the light receiving element, a second substrate provided with the light emitting element, a third substrate provided with the power source circuit, and a casing storing the first substrate, the second substrate, and the third substrate, in which a portion of the battery facing the first substrate, the second substrate, and the third substrate has a smaller sectional area as the portion comes closer to the first substrate, the second substrate, and the third substrate.
US12130175B1
A system for locating optical fiber includes a vehicle's computing device transmitting an acoustic signal and its location, an optical fiber transmitting light signals, an optical detector detecting reflected light due to the acoustic signal, and a server analyzing the reflected light to determine the fiber's location. A method involves receiving a reflected light signal at a computing device, analyzing its properties to identify an acoustic signal's properties, comparing these to a known audio signature emitted from a vehicle, and determining the fiber's location based on the identified vehicle's location. Another method includes a vehicle's computing device transmitting an acoustic signal, determining the vehicle's location, and transmitting this location to a server to determine the optical fiber's location based on the acoustic signal's properties.
US12130174B2
An optical fiber sensing system for abnormal occurrence detection includes a receiving unit configured to receive an optical signal from an optical fiber for sensing. The system includes an identifying unit configured to identify an occurrence of an event and a type of the event that has occurred based on a vibration pattern included in the optical signal. The system includes an acquiring unit configured to acquire a detection condition pertaining to a period corresponding to the type of the event identified by the identifying unit. The system includes a determining unit configured to determine that the event identified by the identifying unit is an anomaly if the detection condition is satisfied.
US12130173B2
The optical fiber sensing system is provided. The optical fiber sensing system comprises an optical fiber measuring module, a floating module, and a containing structure. The floating module disposed in the containing structure has a plurality of floating units. Each floating unit has a mass element and a vibration absorbing structure. It is adapted to apply appropriate tensile force to the optical fiber measuring module by adjusting counterweight of the quality bodies. The vibrating influence to the optical fiber measuring system would be reduced through the vibration absorbing structure.
US12130157B2
Implementations of a resolver sensor system may include a signal amplifier portion configured to be coupled to a magnetoresistive sensor coupled with a movable element where the signal amplifier portion configured to receive a sine signal and a cosine signal from the magnetoresistive sensor; and a sensor offset canceling portion coupled with a signal amplifier portion. The sensor offset canceling portion may be configured to generate a direct current offset correction signal to the signal amplifier portion which uses two or more amplifiers included in the signal amplifier portion to receive the sine signal and the cosine signal and to generate corresponding adjusted digital sine and cosine signals. The signal amplifier portion may be configured to provide the adjusted digital sine signal and the adjusted digital cosine signal to one of the servo signal processor or the system controller for use in determining a position of the movable element.
US12130156B1
Systems and methods for remote Proof-of-Work (PoW) generation.
US12130154B2
An automatic electronic rangefinder has a central processing unit determining whether the rangefinder is perpendicular or parallel to a horizontal plane; a ranging module electrically connected to the central processing unit to detect the distance to a first target object to be measured; an inertial sensing unit electrically connected to the central processing unit to measure the angle between the lengthwise edge of the rangefinder and the horizontal plane; and a shell covering the central processing unit. When the central processing unit determines that the rangefinder is parallel or perpendicular to the horizontal plane, the central processing unit controls the ranging module to measure the distance between the rangefinder and the first target object.
US12130151B2
An information processing device that provides a travel route to a destination to an occupant of a vehicle includes a controller. The controller is configured to acquire travel information obtained by another vehicle that travels on a candidate route to the destination set by the occupant from a second point in time prior to a first point in time when the destination is set to the first point in time in relation to traveling of the other vehicle, and to decide the travel route optimal for driving of the vehicle to the destination based on the acquired travel information.
US12130150B2
An information processing device includes a video obtaining unit that obtains a video of the outside of a vehicle as taken by a camera installed in the vehicle; a position information obtaining unit that obtains the position information of the vehicle; a person detecting unit that detects persons based on the face images included in the video obtained by the video obtaining unit; an eye gaze direction determining unit that determines the direction of eye gaze of each person detected by the person detecting unit; a degree-of-interest determining unit that, based on the directions of eye gaze as determined by the eye gaze direction determining unit, determines the degrees of vehicle interest with respect to the vehicle; and a route setting unit that associates the position information and the degrees of vehicle interest, and sets a route that should be taken.
US12130149B2
A navigation system and a route search method thereof are provided. The navigation system includes a vehicle controller that performs platoon driving and a service server. The service server includes a communicator that communicates with the vehicle and receives traffic information, a database that stores platoon driving information received from the communicator, and a processor that generates a driving route based on the traffic information and the platoon driving information according to a route search request from the vehicle.
US12130144B2
A system can provide a set of expedition proposals that are each selectable by a service provider on a user interface of a computing device to commit the service provider to an expedition. Each expedition can be associated with a configured sequence of tasks to be performed for a given amount of time. Based on a selection of an expedition proposal from the set of expedition proposals, the system can initiate a corresponding expedition for the service provider by (i) matching the service provider with a sequence of tasks, and (ii) transmitting route data to the computing device to cause the user interface on the computing device to display route information for sequential destination locations for the sequence of tasks.
US12130141B2
A navigation system includes a star camera having a field of view. The star camera includes a sun shields that selectively block portions of the star camera's field of view, to prevent unwanted light, such as light from the sun or moon, reaching image sensors of the star cameras. Some sun shields include x-y stages or r-θ stages to selectively position a light blocker to block the unwanted light. Some sun shields use positionable partially overlapping orthogonally polarized filters to block the unwanted light. Some sun shields use counter-wound spiral windows that are selectively rotated to block the unwanted light. Some sun shields a curved surface that defines a plurality of apertures fitted with individual mechanical or electronic shutters.
US12130131B1
A method and apparatus for fitting pipe by creating a mock layout from a parts kit that can include adjustable components. Once the mock layout has been constructed and positioned as desired, a user can take precise measurements of the mock layout to construct the pipe weldment based on the lengths and angles of the mock layout, thus enabling a pipe fitter to construct a weldment to replace the mock layout with, thereby more easily constructing a weldment to fit within a desired location and orientation. The parts kit can include components having adjustable lengths and a plurality of adjustable and/or selectable angle portions.
US12130129B2
Methods, apparatus and systems for processing interferograms in metrology applications are described. In one example aspect, a method includes obtaining an input phase image based on the interferograms, segmenting the input phase image by classifying the input phase image into multiple regions based on the phase value and a location of each pixel, assigning an integer value to each of the multiple regions, and constructing an output phase image based on the input phase image and the phase offset of each of the multiple regions.
US12130121B1
A recording device for mounting on a gun. The recording device includes a recording unit that houses a recording module and a removable power source unit detachably coupled to the recording unit. The removable power source unit houses a battery and memory, wherein the battery is configured for providing power to the recording device while attached thereto and the memory stores recording data from the recording module. The memory of the removable power source unit includes data collected from the recording device and includes a hardware ID or ID code associated with a user of the recording device.
US12130117B2
An alignment mechanism has a base with a front right quadrant, a front left quadrant, a rear right quadrant, and a rear left quadrant. The base further defines a yaw axis and a pitch axis. A ball and socket linkage is located on the base at either the front right quadrant or front left quadrant at the intersection of the yaw axis and the pitch axis. A pressure plate assembly is also on the bottom surface of the base at the other of the front right quadrant and front left quadrant. A spring is in contact with one of the rear right quadrant and rear left quadrant and kitty-corner with the ball and socket linkage, with a yaw alignment surface on the other of the rear right quadrant and rear left quadrant. A pitch alignment surface is also on one of the rear right quadrant and rear left quadrant.
US12130112B1
In some embodiments, an archery bow comprises a limb assembly comprising a first limb and a second limb, the second limb comprising limb threads. An axle assembly is supported by the first limb and the second limb. The axle assembly comprises an axle comprising axle threads. A first connection between the axle assembly and the first limb comprises a fixed connection. A second connection between the axle assembly and the second limb comprises the limb threads engaged with the axle threads. Rotation of the axle with respect to the limb assembly adjusts a distance between the first limb and the second limb.
US12130111B2
An air gun, a removable magazine for an air gun, and associated methods. The air gun includes a safety mechanism that in a safety-on position prevents the trigger from actuating the firing mechanism and closes the gas supply duct, and in a safety-off position enables the trigger to actuate the firing mechanism and opens the gas supply duct to enable actuating the firing mechanism with compressed gas to fire a projectile. The removable magazine includes, a projectile feeder, a cavity for a gas canister, a push valve for selectively releasing pressurized gas from the gas canister, and a valve actuator. The valve actuator includes a socket that releasably receives a nipple of a gas supply coupling carried by an air gun, forms a seal with the nipple, and opens the aerosol valve when coupled with the gas supply coupling.
US12130099B2
A header for a high-pressure heat exchanger includes a first high-pressure transition section with inlets for multiple first high-pressure flow channels that are spaced from one another in a radial direction and collectively arranged in a substantially circular shape. The inlets for the multiple first high-pressure flow channels on a radially outer edge of the first high-pressure transition section are spaced further apart in a circumferential direction from adjacent inlets of the multiple first high-pressure flow channels than radially inward inlets are spaced from adjacent radially inward inlets of the multiple first high-pressure flow channels. The header also includes multiple first high-pressure flow channels extending from the first high-pressure transition section to a second-high pressure transition section that is configured to divide each of the multiple first high-pressure flow channels into at least two first high-pressure sub-flow channels.
US12130096B2
Provided is a heat sink having a clad structure of Co—Mo composite materials and Cu materials, satisfying high heat-sink properties required of the heat sink for use in a semiconductor package with a frame on which a high-output and small-sized semiconductor is mounted, and preventing, when applied to the semiconductor package with a frame, crack of the frame due to local stress concentration. The heat sink has three or more Cu layers and two or more Cu—Mo composite layers alternately stacked in a thickness direction so that the Cu layers are outermost layers on both sides thereof, the Cu layers as the outermost layers each having a thickness t1 of 40 μm or more, the heat sink satisfying 0.06≤t1/T≤0.27 (where T: heat sink thickness) and t2/T≤0.36/[(total number of layers−1)/2] (where t2: Cu—Mo composite layer thickness, the total number of layers: sum of numbers of Cu layers and Cu—Mo composite layers).
US12130095B2
Disclosed herein is a thermal interface material comprising a sheet extending between a first major surface and a second major surface, the sheet comprising a base material; and a filler material embedded in the base material comprising anisotropically oriented thermally conductive elements; wherein the thermally conductive elements are preferentially oriented along a primary direction from the first major surface towards the second major surface to promote thermal conduction though the sheet along the primary direction; and wherein the base material is substantially free of silicone.
US12130088B2
A heat exchanger including a plurality of fluid channel plates laminated on each other to form a cooling water fluid channel through which cooling water flows and an air fluid channel through which air flows. The fluid channel plates have a cooling water inlet hole through which the cooling water is introduced and a cooling water outlet hole through which the cooling water is discharged. Beads block the flow of the cooling water, protrude between the cooling water inlet hole and the cooling water outlet hole, are arranged to surround the periphery of the cooling water inlet hole and the cooling water outlet hole, and are spaced apart such that flow resistance of the cooling water decreases as a flow length of the cooling water increases, so that flow distribution of the cooling water can be uniform.
US12130083B1
Methods, apparatuses, and systems for a closed loop product drying process are disclosed. Heated dry air enters a drying chamber, extracts moisture from a product to be dried, and exits the drying chamber, cooler and wetter. A heat pump air handler dries and warms the air from the drying chamber exhaust, and returns it to the drying chamber, in a closed air loop. The heat pump air handler includes a dehumidifier means in the closed air loop flow path. The dehumidifier means removes entrained moisture from wet air exiting the drying chamber, reheats the air, and returns it to the drying chamber.
US12130078B2
An artificial intelligent food refrigerating device and a method for refrigerating food by using the same are disclosed. An artificial intelligent food refrigerating device according to the present disclosure identifies the size, volume, type, and quantity of food to be put into it and determines a target refrigeration temperature and refrigeration time for the food based on an identification result. The artificial intelligent food refrigerating device and method according to the present disclosure may be associated with an artificial intelligent module, a robot, an augmented reality (AR) device, a virtual reality (VR) device, a 5G service-related device, etc.
US12130065B1
A portable multi-function air conditioner comprises an insulated reservoir configured to hold a liquid and ice, a lid associated with the reservoir to provide selective access to the reservoir, a heat exchanger, at least one pump configured to move a first portion of the liquid through the heat exchanger as a first function and discharge a second portion of the liquid through a spray nozzle as a second function, a fan configured to move air across the heat exchanger, and discharge the air through an outlet port associated with one of the reservoir or the lid, the discharged air intermingling with the discharged second portion of the liquid to condition the air, and a power supply operatively coupled with and providing power to the at least one pump and the fan.
US12130062B2
This refrigeration device comprises: a high temperature side refrigerant circuit in which a high temperature side refrigerant circulates; a low temperature side refrigerant circuit in which a low temperature side refrigerant circulates; and a cascade heat exchanger that cools the low temperature side refrigerant with the high temperature side refrigerant. In the low temperature side refrigerant circuit, a low temperature side decompressor is disposed downstream of the cascade heat exchanger and a temperature sensor is installed in a piping portion between the cascade heat exchanger and the low temperature side decompressor.
US12130059B2
Provided is a heat pump system having a liquid-side on-off valve, a gas-side on-off valve, an ambient temperature detector configured to detect temperature of fluid which passes through a heatsource-side heat exchanger, and a controller. The controller is configured to perform a refrigerant recovery operation for recovering refrigerant from a utilization-side piping section to a heatsource-side piping section by operating a compressor while the liquid-side on-off valve is closed and the gas-side on-off valve is open, and control the compressor such that, when the ambient temperature is higher than or equal to a predetermined value, increase rate of compressor rotation speed is low compared with that of when the ambient temperature is lower than the predetermined value.
US12130053B2
A vent attachment facilitates attaching a coaxial air intake and exhaust vent of a tankless water heater to a Category I vent, such as B-vent. The vent attachment comprises a first end with a coaxial connector comprising a central exhaust pathway and a circumferential air intake pathway. The vent attachment also comprises a second end with a tubular exhaust vent connector in fluid communication with the central exhaust pathway. The vent attachment further comprises a frame that encloses the central exhaust pathway and comprises a mesh configured to provide fluid communication through the frame with the air intake pathway. Additionally, operation of the tankless water heater is modified to ensure that the exhaust generated is suitable for venting through a Category I vent. The tankless water heater maintains a high fuel consumption rate such that the temperature of hot water produced increases throughout each of a plurality of burner stages.
US12130045B1
Certain exemplary embodiments can provide a system, machine, device, and/or manufacture that is configured for operably releasing condensate received from a condensate-producing unit toward a drain without allowing a substantial quantity of gas to flow through the system, machine, device, and/or manufacture, those embodiments including a valve, a spring, and/or a housing.
US12130043B2
Disclosed herein are methods, systems, and devices for allowing access for maintenance and servicing of environmental control systems of prefabricated equipment enclosures. In one embodiment, an enclosure includes a first wall, a first environmental control unit, and a first door. The first door is mechanically coupled with the first environmental control unit and the first wall. The first door is configured to have a first closed position allowing in-service operation of the first environmental control unit for an internal space of the enclosure.
US12130039B2
The disclosed technology includes systems and methods for reducing temperature overshoot of a heating, ventilation, and air conditioning (HVAC) system. The disclosed technology can include a thermostat having a temperature sensor and a controller. The controller can be configured to receive temperature data from the temperature sensor, determine whether a time since the heating cycle of the HVAC unit began is greater than or equal to a predetermined amount of time, and determine whether a current temperature is less than or equal to a low threshold temperature, the low threshold temperature being less than a target temperature. If the current temperature is less than or equal to the low threshold temperature, the controller can determine whether a capacity of the HVAC unit at the end of the heating cycle is greater than a threshold capacity and adjust a response setting of the thermostat by a predetermined adjustment amount.
US12130031B2
A monitoring system for monitoring a home having a plurality of utility devices comprises operation sensors, environment sensors, and a central station. The operation sensors measure performance of the utility devices. The environment sensors generate environment data associated with the home. The central station is configured to: determine conditions of the utility devices based on at least the operation data and the environment data, manipulate at least one of the utility devices based on at least the operation data and the environment data, and make personalized recommendations based on at least the operation data, the environment data, and behaviors of at least one occupant of the home.
US12130022B2
The present disclosure discloses a heating system coupling a passive phase change energy storage sunlight room with an air source heat pump. The heating system includes a passive phase change energy storage sunlight room (7), phase change heat storage units, a to-be-heated room (8), and an air source heat pump air heater arranged between the passive phase change energy storage sunlight room (7) and the to-be-heated room (8), wherein each phase change heat storage unit (11) consists of a plurality of phase change heat storage modules (1). An opening in the front part of each phase change heat storage module faces an interior of the passive phase change energy storage sunlight room, and the phase change heat storage modules located on the top are spliced transversely, and the vent in the top of each phase change heat storage module is connected with the ventilation port of the room.
US12130016B1
A combustor for a turbine engine includes a main combustion chamber, an annular dome, and a secondary combustion chamber positioned downstream of the annular dome. A plurality of first mixing assemblies are disposed through the annular dome and include a pilot mixer. The pilot mixer injects a pilot mixer fuel-air mixture axially into the main combustion chamber and generates a first recirculation zone within the main combustion chamber. A plurality of second mixing assemblies are disposed at the secondary combustion chamber axially aft of the first mixing assemblies and include a main mixer. The main mixer injects a main mixer fuel-air mixture into the secondary combustion chamber to produce combustion gases and to generate a second recirculation zone within the secondary combustion chamber axially aft of the first recirculation zone. The secondary combustion chamber injects the combustion gases into the main combustion chamber.
US12130015B2
A combustion chamber of a gas turbine, wherein downstream of the combustion chamber an expansion turbine with a turbine inlet is arranged. The combustion chamber has an annular design with a component, which has a chamber wall and an end wall arranged next to the turbine inlet and a corner as connection of the chamber wall and the end wall. To increase the cooling performance the component further has an air guidance piece arranged at a distance from the chamber wall with a cooling channel in-between. Further, the corner is fluid tight, wherein the distance of the air guidance piece to the end wall is at least 0.5-times and at most 2-times the lowest width of the cooling channel.
US12130009B2
A steam generator includes a shroud and an annular stepwise helical baffle extending along at least part of a length of the shroud. There is a riser located in a central region of the steam generator. The helical baffle is made up of at least one annular sector of flat plates. The edges of the flat plates may be straight or corrugated.
US12130008B2
A light emission device includes a substrate, a light emission element, and a wavelength converter. The substrate has a first surface. The light emission element is mounted on the first surface and emits excitation light. The wavelength converter is positioned on at least a portion of the first surface and the light emission element. The wavelength converter converts the excitation light into illumination light. The substrate includes at least one of a recess or a projection. The recess has a second surface and a third surface. The second surface is positioned below the first surface. The third surface connects the second surface and the first surface to each other. The projection projects upward from the first surface. The wavelength converter is in contact with at least one of at least a portion of the second surface or at least a portion of the projection.
US12129987B1
A landscape lighting fixture utilizes a cylindrical bollard shroud member which houses an electrical light source, e.g. an LED module. The shroud number extends upwardly from an elongated riser element. A vertically adjustable path hat support system affixed to a path hat circumscribes the shroud member, thereby allowing the path hat to be vertically adjustable in relation to the shroud member. The path hat and path hat support system can also be vertically adjustable along the riser element, without an attached shroud member. In either case, the adjustability of the path hat allows the lighting fixture to provide a wider or narrower light beam angle from the light source without adjusting the illumination from the light source.
US12129980B2
A vehicle lamp includes a metal plate having a light source mounted thereon, a lens that light emitted from the light source enters and passes through to exit forward, and a holder that holds the lens. The metal plate and the lens are positioned to the holder.
US12129975B1
A device can include a body including a sensor and an accelerometer. The sensor can detect contact with the body. The accelerometer can detect a movement of the body. The device can also include at least one processor. The at least one processor can determine an action corresponding to the movement of the body. The action can include at least one of a thermal effect, a production of light, or a transmission of power. The at least one processor can also cause the device to perform the action.
US12129971B2
The cryostat may include an inner vessel configured to accommodate one or more superconducting coils, an outer vessel encompassing the inner vessel, and a thermal shield configured between the outer vessel and the inner vessel. The thermal shield may include an internal cylinder having a first end and an external cylinder encompassing the internal cylinder, the external cylinder having a second end. The thermal shield may also include a seal head configured between the internal cylinder and the external cylinder, the seal head having a first edge and a second edge. The thermal shield may further include a connecting component including a plurality of connectors. Each of the plurality of connectors may be configured to connect the first end of the internal cylinder with the first edge of the seal head and/or the second end of the external cylinder with the second edge of the seal head.
US12129970B2
Provided is a portable cylinder including a tank having a mounting collar coupled to an upper portion of the tank, and a handle assembly attached to the mounting collar. The mounting collar has an upwardly extending portion and a plurality of circumferentially spaced tabs extending radially outwardly from the upwardly extending portion, wherein a respective gap is formed between adjacent ones of the plurality of circumferentially spaced tabs. The handle assembly includes a handle having a shroud portion and a handle portion extending from the shroud portion, and an attachment member configured to be coupled to the shroud portion to prevent rotational movement of the handle relative to the collar, the attachment member having a body, a first projection projecting from a front wall of the body for engaging the shroud portion, and a second projection projecting from a back wall of the body for engaging the shroud portion.
US12129965B2
A manifold system that includes a cylinder assembly formed at least partially or fully of a manifold housing; a fluid reservoir; a gas cylinder assembly that is fluidly connected to the fluid reservoir by a fluid supply conduit fluidly; and wherein atomized non-solid lubricant that flows into a cylinder sleeve of the gas cylinder assembly is used to at least partially or fully lubricate an inner surface of an interior chamber of the cylinder sleeve during the operation of the gas cylinder assembly.
US12129964B2
Techniques for delivering lubricant to a packing assembly of a fluid end of a reciprocating pump include delivering lubricant to a stuffing box that is housing a packing assembly or to a manifold disposed in or around the stuffing box. The lubricant configured to decrease friction between an interior surface of the packing assembly and a reciprocating component moving along the interior surface. Prior to delivering the lubricant to the interior surface of the packing assembly, the lubricant is diverted to multiple radial flow paths circumferentially spaced around a bore in which the packing assembly is disposed. The multiple radial flow paths lead to the interior surface of the packing assembly and the lubricant flowing through the multiple radial flow paths is metered at different flow rates based on a friction gradient across the interior surface of the packing assembly.
US12129951B2
A quick connector includes a coupler fluidically connected by a passage to a first fluid tube. A retainer housing in axial alignment with the passage is installed on the coupler and a movable retainer is installed in the retainer housing in a first position. A second fluid tube having a raised bead formed proximate an end portion of the second fluid tube is permitted to be installed into the retainer housing cavity by the retainer when the retainer is in the first position. Moving the retainer to a second position latches the bead to the retainer housing retaining the second fluid tube to the quick connector.
US12129947B2
A quick connector comprises a sleeving component and a sliding lock. The sleeving component comprises a stop part configured to stop the automatic moving of the sliding lock toward the interior of the sleeve component in the transverse direction when a fluid pipeline is inserted into the sleeving component, and release the stopping of the sliding block when the fluid pipeline is completely pushed into a main body of the sleeving component. The sliding lock further comprises at least one locking hook, and the locking hooks matches a locking catch arranged in the main body of the sleeving component. When a fluid pipeline is completely pushed into the main body of the sleeving component, the locking hooks moves around the locking catch and finally surrounds the locking catch.
US12129945B2
A tube assembly includes a first tube, a second tube, and a tube coupling. The tube coupling is for coupling the first tube to the second tube. The tube coupling may include protrusions, indentations, compressive rings, compressive bands, and/or connection members. The protrusions and/or indentions may be located on the first tube, the second tube, the compressive band, and/or the connection member. The compressive ring and/or compressive band is placed on an outer surface of the first tube and/or the second tube. The compressive ring provides an elastic compressive force to the first tube and/or the second tube such that the protrusion is secured within the indentation. The tube coupling provides a weld-free connection between the first tube and the second tube.
US12129944B2
In an implementation, a method of forming a hydraulic connection between a hydraulic component and a hydraulic hose includes threading a ferrule onto an end section of the hydraulic hose, crimping the ferrule to the hydraulic hose, and threading an annular gasket onto the hydraulic hose between the ferrule and an open end of the end section of the hydraulic hose. The method may include securing the hydraulic hose to a body of the hydraulic component by forming a seal between the body and the hydraulic hose by compression. Threading the ferrule onto the hydraulic hose may include threading an annular ferrule having a profile of a first truncated cone with a first half-aperture, and urging the ferrule towards an interface in the body of the hydraulic component, the interface having a profile of a second truncated cone with a second half-aperture different from the first half-aperture.
US12129943B2
A nipple assembly includes nipple bodies configured so that one end portion of each of the nipple bodies is inserted into a housing so as to be coupled to a cooling medium inlet or a cooling medium outlet of a heat exchanger and a remaining end portion of each of the nipple bodies protrudes outwards from the housing, at least one first sealing unit sealing a gap between the one end portion of each of the nipple bodies and the cooling medium inlet or the cooling medium outlet, a flange portion formed at a position between two end portions of each of the nipple bodies to be coupled to the housing, and a second sealing unit including a first sealing portion sealing a gap between the flange portion and the housing and a second sealing portion configured to extend from the first sealing portion.
US12129942B2
A fitting apparatus for fluidly coupling a plurality of pipes together includes a flexible bladder which fluidly couples a plurality of pipes together. A rigid shell is positionable around the bladder in an attachment position. The rigid shell comprises two portions which are couplable to each other to position the shell in the attachment position. Collars are provided which threadably attach to the rigid shell.
US12129916B1
Systems and methods for a locking differential assembly. The locking differential assembly, in one example, includes an input gear configured to rotationally couple to an upstream component, a case coupled to the input gear, and a locking clutch configured to, in an engaged configuration, lock rotation of the case and a side gear. The locking differential assembly further includes an actuation system configured to engage and disengage the locking clutch based on a steering angle.
US12129913B2
The present disclosure relates to an electric drive axle, including a driving assembly, a power coupling gear, a first gear transmission assembly, a second gear transmission assembly and two half shafts connected by a differential, the driving assembly is used to drive the differential. In the above way, the electric drive axle and the electric vehicle realize 3 shifting speeds, and can timely engage in different speeds according to the vehicle load, road conditions, transportation time requirements, etc., so as to realize the efficient operation of the vehicle, improve the operation efficiency, reduce energy consumption, meet the power demand of commercial vehicles with diverse loads and working conditions, and obtain high transportation efficiency and economic benefits.
US12129911B2
The design of chain links for energy chains for movably carrying cables, hoses and the like. The chain link consists of a plurality of individual parts, namely two side plates made of plastic, comprising an interior side facing the interior of the chain link, an exterior side facing away therefrom and two narrow sides running substantially parallel to the longitudinal direction, and at least one, more particularly two transverse connecting pieces for detachably connecting the side plates, comprising a center part and a fastening portion at each end of the transverse connecting piece on both sides. The side plates have, on at least one narrow side, a corresponding fastening region for frictionally fastening a transverse connecting piece, namely a clamping receptacle which has two clamping surfaces, which are opposite one another in the longitudinal direction and between which a complementarily shaped fastening portion of the at least one separate transverse connecting piece is clamped. Each transverse connecting piece has two support protrusions on each fastening portion, each support protrusion having a support surface for resting against the interior side of the side plate in order to achieve a robust connection. Providing the side plate, in the central region between the fastening regions, with a special functional cut-out in the plate body, which cut-out facilitates additional functions or application expansions.
US12129895B2
A bistable electromagnetic clutch is provided that includes a first part, a second part and an spring part. The first part includes a yoke with a plurality of iron cores, and an electromagnetic coil on each of the iron cores. The second part includes a moving carrier disc and a magnetic conductive disc that is fixed on a side of the moving carrier disc that is away from the yoke. Several magnets are fixed on the moving carrier disc, and the iron cores and the magnets are provided in a correspondence relation. The spring part is configured to keep the moving carrier disc and the yoke in normally separated positions. Two adjacent electromagnetic coils form a group, two electromagnetic coils in a same group are wound to form a group of windings with identical magnetic polarities, and corresponding two magnets form a group of magnetomotive forces with identical magnetic polarities.
US12129876B2
Elastomeric actuators and methods of making the same are provided herein. In some examples, an actuator includes a body comprising a plurality of pairs of frustums, wherein the body is configured to receive a fluid to extend the actuator and to remove the fluid to contract the actuator. In some examples, each pair of frustums includes two thin frustum shells sharing a common base circle diameter.
US12129875B2
A flow path switching valve includes a block-shaped body having a first opening and a second opening which communicate with each other via a linear first oil path, and a third opening which communicates with the first oil path via a linear second oil path; a valve body which is provided so as to be rotatable relative to the body, and in which a communication flow path is formed that allows two openings to communicate with each other depending on the rotation position; and a locking protrusion which regulates the rotation range of the valve body in order to select the rotation position of the valve body to be a predetermined rotation position where two openings of a predetermined combination among the three openings communicate with each other via the communication flow path of the valve body.
US12129874B2
The present disclosure relates to a radial piston hydraulic device distributing flow by pilot operated check valves and an operating method thereof. The radial piston hydraulic device includes a housing, a plurality of piston assemblies, a main shaft, first pilot operated check valves, second pilot operated check valves, and a valve plate. The first pilot operated check valves have a same number as the plurality of piston assemblies and are one-to-one corresponding to the plurality of piston assemblies. The second pilot operated check valves have a same number as the plurality of piston assemblies and are one-to-one corresponding to the plurality of piston assemblies. The radial piston hydraulic device can be used not only as the hydraulic motor, but also as a hydraulic pump, and can be used in a hydraulic system that need to realize power recovery functions.
US12129868B2
A convector includes a rotor having a shaft extending along an axis of rotation, and a plurality of discs offset from one another along the axis of rotation and mechanically coupled to and rotatable with the shaft. The convector also includes a stator having a plurality of plates offset from one another along the axis of the shaft. Each plate of the plurality of plates defines a through-hole configured to receive the shaft and an opening configured to receive a corresponding disc of the plurality of discs. Rotation of the shaft causes each disc to rotate at least partially within the opening defined by the corresponding plate, and relative to the corresponding plate.
US12129860B2
This application provides a fan and an electronic device. The fan includes a body, and an air duct, an air outlet and a flow guiding inlet are formed in the body; the air duct includes an air inlet area and an air outlet area, and a flow guiding member is disposed in the air outlet area; the flow guiding member and the body form a first channel, a second channel, and a third channel. After a main airflow in the air inlet area enters the first channel and the third channel, a negative pressure area is formed at the flow guiding outlet, a differential pressure exists between air pressures in the negative pressure area and the second channel, and the differential pressure enables air to enter the flow guiding cavity from the flow guiding inlet to form an induced airflow, thereby increasing an air output.
US12129859B1
A compressor comprising: a first compressor wheel comprising a first chamber configured to retain a medium, a first impeller disposed within the first chamber and configured to revolve around a longitudinal axis of the compressor, and a first diffuser coupled to the first chamber; and a second compressor wheel comprising a second chamber disposed radially outwards of the first chamber relative to the longitudinal axis, wherein the second chamber is configured to receive the outputted medium from the first chamber, a second impeller disposed within the second chamber and configured to revolve around the longitudinal axis of the compressor within the second chamber, and a second diffuser coupled to the second chamber, wherein each blade of the first impeller defines a fillet extending along an outer edge of the blade, and wherein a width of the fillet along a surface of the respective blade varies along the longitudinal axis.
US12129852B2
The present invention discloses a compressor comprising: a vessel; a crankshaft including an annular mounting recessed groove which is formed on its outer circumferential surface; a compression mechanism disposed over the crankshaft, and configured to compress the refrigerant sucked from an outside through rotation of the crankshaft; and a stopper which consists of a first stopper member and a second stopper member, and includes a through-hole which is formed between the first stopper member and the second member. The crankshaft is inserted into the through-hole of the stopper, and the stopper is engaged and fixed on the annular mounting recessed groove.
US12129850B2
A screw rotor is made out of polymer. The screw rotor includes a shaft with a rotor body on it. The polymer of the shaft is reinforced with fibers. The shaft features elements that engage the rotor body or corresponding elements on the rotor body, such that the elements prevent an axial and/or rotational movement of the shaft with respect to the rotor body.
US12129849B2
One embodiment of a method for operating an internal combustion engine under a pressure less than atmospheric pressure includes the steps of positioning a vacuum pump such that said vacuum pump is in fluid communication with a crankcase of said internal combustion engine, connecting a discharge of said vacuum pump to a separator, wherein a portion of said discharge of said vacuum pump condenses in said separator, connecting a vapor discharge of said separator to a filter, wherein said filter removes a portion of volatile organic compounds from said vapor discharge, and venting said filter to an ambient atmosphere.
US12129843B2
A positive displacement pump includes a housing surrounding a drive chamber and a diaphragm compartment. A drive element is inside the drive chamber. A diaphragm is inside the diaphragm compartment and divides the diaphragm compartment into a fluid chamber and a cavity. A shaft connects the drive element and the diaphragm. A breather valve is fluidically connected to the cavity and is configured to allow air to exit the cavity. The cavity is fluidically disconnected from the drive chamber.
US12129841B2
A vacuum pumping apparatus may include: a common pumping line having a plurality of pumping line inlets and a pumping line outlet, each pumping line inlet being configured to couple with an outlet of an associated plurality of vacuum processing chambers; at least one primary vacuum pump in fluid communication with the pumping line outlet to pump gas from each vacuum processing chamber; and control logic operable to control operation of the primary vacuum pump in response to an indication of an operating state of the plurality of vacuum processing chambers. In this way, the performance of the primary vacuum pump can be adjusted to match the load provided by the processing chambers and when there is an excess capacity, the performance of the primary vacuum pumps can be reduced, which can lead to significant energy savings and reduce wear on the pump.
US12129840B2
A capacity control valve includes: a valve housing provided with a suction port through which a suction fluid of a suction pressure passes and a control port through which a control fluid of a control pressure passes; a valve body driven by a solenoid; a spring that biases the valve body in a direction opposite to a direction of driving by the solenoid; a CS valve that includes a CS valve seat and the valve body, and that moves the valve body to open and close a communication between the control port and the suction port, the capacity control valve opening and closing the CS valve to control the control pressure, in which the control fluid of the control pressure is suppliable to a back side of the valve body.
US12129839B2
A liquid delivery system includes a reciprocating drive and a liquid cylinder comprising a liquid piston, operably driven by the reciprocating drive, to pump a liquid along a flow path to a liquid applicator. The liquid delivery system includes a coupler configured to couple the liquid piston to the reciprocating drive. The coupler includes a plurality of collar elements and a biasing member configured to apply a biasing force on the plurality of collar elements to retain the collar elements in a position that forms a collar that couples the liquid piston to the reciprocating drive.
US12129837B2
An electrochemical heat transfer device for a hot water tank utilizes an electrochemical hydrogen compressor to pump hydrogen into and out of a tank having a metal hydride forming alloy therein. The absorption of hydrogen by the metal hydride forming alloy is exothermic, produces heat, and the desorption of the hydrogen from the metal hydride forming alloy is endothermic and draws heat in. An electrochemical hydrogen compressor may be configured between to tanks and pump hydrogen back and forth to form a heat transfer device, such as a hot water heater. A heat transfer device may be coupled with the tank or may comprise the outer surface of the tank to transfer heat to an object or to the surroundings. A closed loop may be configured having two tanks and one or two electrochemical hydrogen compressors to pump the hydrogen in a loop around the system.
US12129826B2
The invention provides a method for handling a blade (11) for a horizontal axis wind turbine (1), the blade extending longitudinally between a blade root (111) and a blade tip (112), the method comprising—supporting the blade (11) with one or more cranes (3), moving, by means of the one or more cranes (3), the supported blade (11) so as to be placed on one or more first support elements (4111) of a first support device (411) and on one or more second support elements (4121) of a second support device (412), removing the support of the one or more cranes (3), so as for the blade (11) to be supported by the one or more first support elements (4111) and the one or more second support elements (4121) on which the blade is placed, the second support device (412) being located between the blade root (111) and the blade tip (112), and the first support device (411) being, compared to the second support device, located closer to the blade root, moving the first and second support devices (411, 412) so as to move the blade (11) supported by the first and second support elements (4111, 4121), and/or moving a third support device (413), so that the third support device (413) assumes a support position between the second support device (412) and the blade tip (112), and removing, while the third support device (413) is in the support position, the support of the one or more second support elements (4121) so as for the blade (11) to be supported by one or more third support elements (4131) of the third support device, and by the one or more first support elements (4111).
US12129824B2
A method of installing an offshore wind turbine includes the step of raising a full-length tower for the offshore wind turbine by moving it longitudinally from a container in a substructure, the substructure being a support structure for the wind turbine, wherein the substructure is arranged with a container configured for housing a tower for the wind turbine substantially in its entirety.
US12129820B1
A tubular wave energy converter configured to remain afloat near the surface of a wave field and trap a water column oscillating asymmetrically to the wave field in which the converter is located. Water column oscillations create a pressure flux providing motive power for a generator. The converter, generator and a powered payload making up an autonomous wave powered device are packaged to fit within and be deployed by a torpedo launcher. The autonomous device may be deployed above or beneath the surface. Device buoyant characteristics are configured to maintain the device afloat and self-righting toward an upright oriented for operation in the wave field.
US12129797B2
A heat management system includes a fuel tank storing a fuel; a first heat exchanger thermally coupled to the fuel tank; a hydraulic pump for circulating a hydraulic fluid; a hydraulic circuit including first and second hydraulic lines fluidly coupled to the first heat exchanger and the hydraulic pump, such that the first heat exchanger brings the hydraulic fluid and the fuel into a heat exchange relationship; an oil circuit; and a second heat exchanger thermally coupled to the oil circuit and at least one of the first and second hydraulic lines, such that the second heat exchanger brings the hydraulic fluid and the oil into a heat exchange relationship, thereby allowing heat transfer between the fuel and the oil via the hydraulic fluid.
US12129794B2
A vane assembly for a gas turbine engine which is a single unitary component that includes an aerofoil. A leading edge passageway is disposed proximal to a leading edge of the aerofoil and configured to receive a flow of a fluid therein. The vane assembly further includes a connecting passageway fluidly communicating the leading edge passageway with a trailing edge distribution passageway that is spaced apart from the leading edge, the leading edge passageway and a trailing edge of the aerofoil. The vane assembly further includes a plurality of trailing edge passageways disposed proximal to a pressure surface of the aerofoil and extending from the trailing edge distribution passageway towards the trailing edge along a chordwise direction. Each trailing edge passageway is configured to discharge the fluid through a corresponding passageway outlet disposed on the pressure surface and in fluid communication with a corresponding trailing edge passageway.
US12129792B2
A method for cleaning a steam system including an intermittent operation processing step and a commissioning processing step are executed. The intermittent operation processing step includes: a no-load operation step in which a gas turbine is operated with no load, with a steam stop valve and a bypass valve closed; during the no-load operation step, a pressure accumulating step in which steam is accumulated in a pressure accumulation region; and, after the pressure accumulating step, an intermittent blowing step in which the bypass valve is opened, and steam in the pressure accumulation region is allowed to flow into a condenser. The commissioning processing step includes: a commissioning step in which the gas turbine is commissioned with the steam stop valve closed and the bypass valve open; and a continuous blowing step in which steam from a waste heat recovery boiler is allowed to flow into the condenser.
US12129781B2
An exhaust gas aftertreatment device 30 of an internal combustion engine 1 includes a catalyst 24 provided in an exhaust passage 4, a first branch passage 31 having one end 35 connected to an exhaust passage downstream of a catalyst, a second branch passage 32 having one end 38 connected to the exhaust passage upstream of the catalyst, a tank 33 to which the other end 36 of the first branch passage and the other end 39 of the second branch passage are connected and capable of storing exhaust, a valve mechanism 34 configured to switch open and closed states of the first branch passage, the second branch passage, and a downstream portion 41 of the exhaust passage downstream of a branch point 37 to which the one end of the first branch passage is connected, and a control unit 100 configured to control the valve mechanism.
US12129780B2
A combustion engine for a motor vehicle includes an output shaft, an intake tract, an exhaust gas tract, an exhaust gas aftertreatment device disposed in the exhaust gas tract, a heating element disposed in the exhaust gas tract upstream of the exhaust gas aftertreatment device, an electrically assisted exhaust gas turbocharger, and a conduit element which is fluidically connected to the exhaust gas tract at a first connection point disposed downstream of the exhaust gas aftertreatment device and at a second connection point disposed upstream of the heating element.
US12129778B2
A system comprising (i) a vehicular compression ignition engine comprising one or more engine cylinders and one or more electronically-controlled fuel injectors therefor; (ii) an exhaust line for the engine comprising: a first emissions control device comprising a first honeycomb substrate, which comprises a hydrocarbon adsorbent component; and a second emissions control device comprising an electrically heatable element and a catalysed second honeycomb substrate, which comprises a rhodium-free platinum group metal comprising platinum, wherein the electrically heatable element is disposed upstream from the catalysed second honeycomb substrate and wherein both the electrically heatable element and the catalysed second honeycomb substrate are disposed downstream from the first honeycomb substrate; a third emissions control device, which is a third honeycomb substrate comprising an ammonia-selective catalytic reduction catalyst disposed downstream from the second emissions control device; and one or more temperature sensors located: upstream of the electrically heatable element and/or upstream of the first honeycomb substrate; and between the electrically heatable element and the catalysed second honeycomb substrate; and (iii) an engine control unit comprising a central processing unit pre-programmed, when in use, to control both a heating activation state of the electrically heatable element; an injection timing strategy of the one or more electronically-controlled fuel injector to increase the temperature of at least the first emissions control device following key-on/cold-starting a vehicle comprising the system, wherein the one or more temperature sensors are electrically connected to the engine control unit for feedback control in the system.
US12129777B2
An internal combustion engine includes at least one cylinder crankcase, at least one cylinder head (1), at least one overhead camshaft (2), at least two rocker arms (3) which are driven by the camshaft (2) and actuate the combustion valves, the camshaft(s) (2) being mounted in the cylinder head housing, and an oil supply line (9) which is situated in particular in the area of the top face of the cylinder head (1) for lubricating camshaft bearing brackets (10) and the rocker arm brackets (11).
US12129768B2
A unitized build assembly for a gas turbine engine includes an exhaust duct, a hot section with a locking structure and including a combustor and turbine section. The hot section at least partially circumferentially surrounds the exhaust duct. The build assembly includes a compressor section with an interface structure and is proximal to the hot section. The hot section at least partially circumferentially surrounds at least part of the compressor section and the locking structure is configured to engage the interface structure to limit movement of the hot section relative to the compressor section.
US12129761B2
A casing of an aircraft turbomachine includes an annular shell extending around an axis A and made of a composite material having fibers that which are woven and embedded in a resin. An annular layer made of abradable material extends inside the shell, around axis A and is obtained by spreading and polymerizing a paste. Support panels extend around axis A and are interposed between the shell and the abradable layer.
US12129756B2
Optic fibers are embedded within the body of a casing section making up a wellbore casing string. The optic fibers are used to detect damage or deformation of the casing string over the lifespan of a wellbore.
US12129755B2
A system and method are provided for extracting information regarding a drill site including forming one or more documents having one or more raw comments regarding a well site. Raw data may be extracted from the one or more documents to produce extracted raw data. The extracted raw date may be pre-processed by removing ambiguity, artifacts, and/or formatting errors from the one or more raw comments to produce pre-processed data. Topics data may be extracted from the pre-processed data using a natural language processing (NLP) algorithm to produce extracted topics data. Measurement data may also be extracted from the pre-processed data using the NLP algorithm to produce extracted measurement data. The extracted topics data and the extracted measurement data may be aggregated to form a set of discrete data points, such as calibration points, per comment to produce aggregated data and one more calibration points may be identified from the aggregated data. The results of the one or more calibration points may then be presented.
US12129748B1
An Electric Submersible Pump (ESP) is installed in a production branch of a Y-tool apparatus. A bypass branch of the Y-tool apparatus permits an intervention tool on a coiled tubing string to bypass the ESP for intervention operations in the wellbore. A permanent dynamic seal in the bypass branch includes an inflatable elastomeric chamber that forms a seal around the coiled tubing string while the coiled tubing is run-in and pulled out. A ball valve is also provided in the bypass branch. The dynamic seal and ball valve eliminate the need for blanking plugs to be retrieved and reset with slickline operations.
US12129747B2
A downhole electric submersible pump (ESP) assembly. The downhole ESP assembly comprises a hybrid permanent magnet motor (PMM) comprising a first drive shaft, a stator, and a rotor comprising a first permanent magnet element, a second permanent magnet element, and an induction squirrel cage, wherein the rotor is mechanically coupled to the first drive shaft and disposed within the stator; a seal section having a second drive shaft coupled to the first drive shaft; and a pump assembly having a third drive shaft coupled to the second drive shaft.
US12129743B2
A downhole electrical power generation device is provided that includes at least one magnetic element, an electrically conductive element, and a member configured to be positioned within downhole fluid and to vibrate when the downhole fluid flows across a surface of the member. One of the magnetic element and the electrically conductive element is positioned on the member, and the other is configured to be positioned such that the electrically conductive element is located in a magnetic field produced by the at least one magnetic element to generate electrical power on vibration of the member. A method of generating electrical power downhole is further provided.
US12129740B2
A downhole component can include a support body that includes a surface that defines at least a portion of a fluid passage; a composite matrix for scale mitigation supported by the surface of the support body where the composite matrix includes a lattice material that defines a lattice and magnetic material disposed in interstices of the lattice; and a cover layer disposed on the composite matrix.
US12129737B1
It is desirable to prevent the unintended generation of electricity by permanent magnet motors in a submersible pumping system used to recover fluids from a wellbore. A pumping system designed to prevent the unintended generation of electricity includes a pump intake that provides a path for the wellbore fluids to enter the pump. The pumping system further includes a flow control valve assembly connected to the pump. The flow control valve assembly has a sliding sleeve and a valve control mechanism that moves the sliding sleeve between open and closed positions on the intake of the pump.
US12129728B2
A downhole blowout preventer has a blowout preventer tubing string containing a circulation unit, a packer unit and a pressure-building unit connected in sequence from top to bottom. The pressure-building unit is configured to be activated in response to a command, so as to build up pressure in a space inside the blowout preventer tubing string. The packer unit is configured to be activated when a pressure in said space reaches a first predetermined value, so as to seal an annulus between said blowout preventer tubing string and an external casing or borehole. The circulation unit is configured to be activated when the pressure in said space reaches a second predetermined value, thereby creating a circulation path between an interior and an exterior of the blowout preventer tubing string. The first predetermined value is less than the second predetermined value.
US12129725B2
A clamp for a line including a body, and a control line contact surface, the clamp being responsive to a selected input to facilitate displacement of the line. An expandable tool including a component having a first dimension prior to activation and a second dimension after activation, a control line disposed adjacent the component, and a clamp initially securing the control line, the clamp comprising at least one of 1) a fastener and 2) a body, at least a portion of either of which being responsive to a selected input to facilitate displacement of the control line. A method for deploying a tool with a control line including securing the control line to the tool, reacting the at least a portion of the clamp to the input, and displacing the control line. A borehole system including a borehole in a formation, and an expandable tool disposed in the borehole.
US12129723B2
Methods and systems for managing dielectric properties of a pulsed power drilling fluid are provided. In one embodiment, the methods include introducing a drilling fluid into a drilling pipe that extends into a portion of a wellbore; separating the drilling fluid into a solids rich portion and a solids lean portion in the drilling pipe at a location proximate to a pulsed power drill bit; allowing the solids lean portion of the drilling fluid to flow through the pulsed power drill bit; and drilling at least a portion of a wellbore. In some embodiments, the methods and systems include passing the drilling fluid through one or more hydrocyclones. In some embodiments, the methods and systems include passing the drilling fluid through one or more centrifuges.
US12129715B2
The invention relates to a safety apparatus for cable power lines of submersible electric motors used as drives of centrifugal pumps for the production of oil and other formation fluids. The apparatus contains a housing with a slot for a cable, and clamps arranged along the edges of a first side wall of the housing. Each clamp has one end hinged on the first side wall of the housing, and another end hingedly connected to a corresponding lock. Each lock contains connecting loops with protrusions, and the clamps each clamp is made with recesses and a thrust protrusion corresponding to the protrusions of the loops. Each lock further contains connecting protrusions to create a rigid connection a second side wall of the housing when the lock and the housing are pulled together.
US12129699B2
In a door hinge device for the vehicle, in the vehicle without a B pillar, the four-section link including the first link formed of the first vehicle body rod and the first door rod that are mutually hinged and the second link formed of the second vehicle body rod and the second door rod that are mutually hinged is applied between the vehicle body bracket and the door bracket fixed to each hinge portion of the vehicle body and the door, it enables the opening/closing operation of the door without a rotational interference with the vehicle body or other door.
US12129697B2
A lock with an extended bolt throw comprising a back plate, a locking bolt having a rack gear profile on at least a portion of one side, slidably mounted to the back plate movable between a first position and a second position. An accelerator gear mounted to the back plate movable along an arcuate path between a first and second position. The accelerator gear comprising a curved edge having teeth which engage the rack gear profile of the locking bolt, and an opposing edge having a centrally located notch for engagement of a cam of a lock cylinder. Wherein as the cam rotates about the lock cylinder it engages the notch and urges the accelerator gear from the first position to the second position, which urges the locking bolt from the first position to the second position.
US12129682B2
An energy dissipation device is disclosed. The device includes a container, where the container includes a top plate that is horizontally slotted on the container. In addition, the device includes at least one movable plate is inserted through a slot inside the container, and at least two holes inserted in the at least one movable plate. Moreover, the device includes at least two rods partially threaded at both sides of the container. In some implementations, the device may include a frame. In addition, the device includes a damper fixed inside the frame, and a plurality of braces installed in the frame to provide support to the damper. Moreover, the device includes at least one beam and at least one horizontal plate fixed to a bottom face of the at least one beam. A method of assembling an energy dissipation device is also disclosed.
US12129681B2
An alignment tool for aligning and installing a plurality of pickets on a fence segment. The alignment tool comprises a body portion, and a picket level indicator. One or more upper guides and a lower guide assembly can be separated by a guide gap. The guide gap is at least as wide as a first cross member height of a first cross member of the fence segment. The alignment tool is configured to selectively attach and slide along the first cross member of the fence segment and position the picket level indicator at a selected height relative to the first cross member. The one or more upper guides and the lower guide assembly are configured to slide a forward direction and a reverse direction on the first cross member.
US12129677B2
A modular crypt structure comprising a frame, a module insert defining a chamber and a closure panel and methods of constructing the same are disclosed. The chamber functions as a crypt module and receives bodily remains or portions thereof. The chamber is closed by attaching a closure panel, such as a stone crypt front to the frame. The modular crypt frame may comprise a plurality of horizontal bars and a plurality of vertical bars. A method of constructing a modular crypt structure comprises erecting a frame, providing at least one module insert, configuring the insert to define a chamber adapted to receive bodily remains, and closing the crypt module. A modular crypt system including a niche side wall is also disclosed having a niche side wall frame, a niche insert defining a plurality of niches positioned within the frame, and a closure panel positioned on the niche side wall frame.
US12129671B2
A device for leveling and aligning tiles and method for leveling and aligning tiles are disclosed. In one embodiment, the leveling device includes a body and two spaced and parallel strip members extending transversely from the body. Each of the spaced and parallel strip members extend to the front and rear of the body. Two opposing lateral open windows are formed in the body. A breakaway section is defined along the body. A wedge device is provided for penetrating one or more of the two opposing lateral open windows and exerting a force on the tiles for leveling them relative to each other.
US12129666B2
A method for determining an edge profile of a custom decorative article to be installed in an installation area is disclosed, the installation area having a perimeter having a plurality of corners. A computing device receives data indicative of a plurality of coordinates corresponding to the plurality of corners of the perimeter of the installation area. Based on at least first, second, and third coordinates respectively corresponding to first, second, and third corners of the plurality of corners of the perimeter of the installation area, the computing device determines dimensional and/or geometric characteristics of a pair of opposed portions of the edge profile that, in an installed position, are configured to meet to form a corner of the custom decorative article when installed at the second corner of the perimeter of the installation area.
US12129664B2
A method for manufacturing a panel having a substrate, a decorative layer that includes a digital print, and a translucent or transparent wear layer. The method may involve providing the substrate with the digital print by jetting one or more inks from a set of inks using a digital inkjet printer. The ink may include a binding agent and/or a primer or an adhesion layer may be provided between the digital print and the translucent or transparent wear layer. The digital print may be performed directly on the substrate.
US12129646B2
One variation of the tile display includes a set of tile assemblies, each tile assembly includes: a base plate; a tile panel; a tile interface; and a set of linear actuator assemblies arranged in a radial pattern about the base plate and cooperating to constrain the tile panel in angular roll, linear heave, and linear sway motion relative to the base plate. Each linear actuator assembly includes: a bearing housing defining a linear bearing, a floating bearing, and a through-hole; an actuator mounted to the bearing housing; a distal link coupled to the tile interface; a first support boom running through the linear bearing; a second support boom running through the floating bearing; and a driven boom running through the through-hole of the bearing housing. Each tile assembly also includes a primary controller configured to maneuver tile panels over ranges of angular pitch, angular yaw, and linear surge positions.
US12129641B1
A quick-cleaning drain for quick replacement of cleaning parts, including a drain body, the drain body is embedded with a drain core, the drain core is provided with a quick-cleaning mechanism which is quickly removable, the quick-cleaning mechanism matches a draining channel of the drain core, the quick-cleaning mechanism includes a lifting rod and a quick-cleaning member, the quick-cleaning member matches the draining channel for draining water and blocking debris in the water, the upper surface of the quick-cleaning member is provided with a connecting end, the bottom of the lifting rod is provided with an engaging end, and the engaging end matches and is removably fixed to the connecting end.
US12129637B2
The invention relates to a urinal system (10), a water consumer system having such a urinal system, and a method for operating a urinal system. A urinal controller (8) of the urinal system has a data processing system (9) and/or is connected to a data processing system (9) which is designed to retrieve and/or receive and computationally evaluate data captured by at least one HF motion sensor (5) provided on a urinal bowl (1) and/or a urinal outlet (4) of the urinal system, and to recognize one of the following malfunctions based on the evaluated data and/or to initiate an action in order to avoid one of the following malfunctions: that the urinal outlet is obstructed, and/or that there is a pressure fluctuation in a wastewater system connected to the urinal system, and/or that a fluid inlet (2) and/or an inlet valve (3) of the urinal system is malfunctioning, and/or that there is a failure of the HF motion sensor, and/or to recognize a predefined urinal usage situation and/or frequency of use on the basis of the evaluated data and, based on this, to adapt an opening time and/or an opening position and/or an opening frequency of the inlet valve to in a subsequent urinal flushing process.
US12129633B2
A handheld showerhead assembly including a handheld showerhead and a receiver to which the handheld showerhead is releasably securable. The handheld showerhead includes a push-button on a handle portion thereof for releasing the handheld showerhead from the receiver. The handheld showerhead is maintained securely engaged with the receiver until the push-button is depressed to permit removal of the handheld showerhead from the receiver. Cooperating magnetic components attract the handheld showerhead to the receiver.
US12129629B2
A control device and method for controlling a disengaging actuator (1) of a tool attachment, the device comprising a three-state switch (2), with a middle neutral position (20), a first end position (21), and a second end position (22), a control unit (3, 3′), having an input corresponding to an activation of the first end position (21), an electro-valve (4) coupled hydraulically to the disengaging actuator (1), having a coil (40), a first control line (41) and a second control line (42) coupled respectively to first and second terminals of the coil (40) of the electro-valve, wherein one of the first and second control lines is coupled to the second end position (22) of the three-state switch and the other of the first and second control lines is coupled to an output of the control unit, such that both control lines have to be activated to allow disengagement.
US12129628B2
A method for preventing prime mover stall for a work machine including a hydraulic system having a plurality of control valves served by a hydraulic pump. The method can include determining an actual required flow rate value for the plurality control valves and a total maximum flow rate to the plurality of control valves that will enable the prime mover to operate without stalling. The method can also include operating the plurality of control valves such that the combined total flow of the plurality control valves is at or below the total maximum flow rate such that the pump operates at a condition below which prime mover stall will occur. The method can also include setting a flow sharing allocated specific criteria in which the flow reduction takes place during a flow saturation condition for each of the plurality of control valves such that the total sum of the flow rates (calculated based on the criteria) is equal to or less than the total maximum flow rate.
US12129627B2
Provided is a work vehicle capable of satisfying a user's demand to brake performance in a flexible manner. A wheel loader 1 comprises a controller 5 storing a plurality of control characteristics each of which is set such that a brake valve control pressure Pi of a solenoid proportional valve 45 increases as a pedal angle θ of a brake pedal 43 increases, and under the condition where a pedal angle θ is equal to or less than a predetermined pedal angle θ, an increase rate of the brake valve control pressure Pi with respect to the pedal angle θ varies. In a case where the pedal angle θ detected by a potentiometer 33 is equal to or less than the predetermined pedal angle θth, the controller 5, calculates the brake valve control pressure Pi based on the selected one control characteristic.
US12129625B1
A hydraulic system for a service vehicle wherein a hydraulic pump is powered by the vehicle engine to energize a hydraulic circuit that can power multiple interchangeable implements and hand tools. The multiple interchangeable implements include a lift assembly mounted to the flatbed of the truck. The lift assembly includes a mini skid steer which is hydraulically lifted on and off the platform of the flatbed. Additionally, the interchangeable implements include a crane arm that is disposed on the flatbed of the truck. Furthermore, the interchangeable implements also include a hydraulic arm assembly with several hydraulic attachments. These attachments may include a bucket, a drill, a breaker and the like.
US12129621B2
A platform, system, and method for simulating critical rock collapse of surrounding rock in underground engineering includes: four vertically arranged reaction walls defining a square reaction space, and a base mounted at a lower end opening of the wall; and a row of horizontally arranged stress loading plates at a side of each wall close to the reaction space, and a reaction beam above this space, where the reaction beam, the stress loading plate, and the base define a loading space, and the loading space is configured for placement of a surrounding rock simulation block to be tested; the stress loading plate capable of moving horizontally in a direction of the reaction wall, and the reaction beam capable of moving in a vertical direction, so as to load the surrounding rock simulation block; and the stress loading plate and the reaction beam being driven by linear motion units for movement.
US12129620B1
Disclosed is a method for repairing an aquifer in a coal mine area by grouting, including: drilling a survey hole in a ground area corresponding to a water inflow position from ground surface to a caving zone in a goaf; determining a target layer for grouting in the survey hole based on drilling data collected from the survey hole while drilling; changing the survey hole to a grouting hole; measuring a first water level from the grouting hole; grouting through the grouting hole; changing the grouting hole to an observation hole; measuring a second water level from the observation hole; and determining a water retention level based on the first water level and the second water level.
US12129615B2
A steel serrated plow guard with combination carbide insert which can be mounted on most plow blades is provided. The plow guard can be mounted onto most plow blades through the universal mounting elongated slot. The exemplary plow guard for mounting to a snowplow includes a plow guard body, a plow guard wear surface along the plow guard body, at least one enlarged outer edge on the plow guard body, at least one serrated cutting surface attached to the plow guard wear surface, an elongated horizontal slotted punch aperture along the plow guard body, and at least one longitudinal carbide matrix groove.
US12129614B2
A barrier-wall structure having a retaining wall with a back support surface supported by backfill adjacent thereto, wherein the backfill is municipal solid waste processed into fill-material in the form of a multiplicity of biologically-inert compacted pieces.
US12129606B2
A method for permeable pavement of dirt interception comprises laying a permeable structure layer with a toothed groove between the base layer and the transition surface of the cushion layer or directly setting the upper surface of the cushion layer as a toothed structure; in the base layer, laying at least one layer of dirt interception trough; providing a water-permeable coating or fine sand at the bottom of the sewage interception trough; the present invention traps the dirt between the base layer and the cushion layer that are most likely to cause void blocking in the base layer, close to the shallow part of the surface layer is used to remove dirt by high-pressure flushing operations.
US12129601B2
Disclosed are non-treated, creped tissue webs, and tissue products produced therefrom, having low stiffness and surface lint. The inventive products may be produced by a print creping process adapted to dispose a non-crosslinked latex polymer on at least one of the outer surfaces of the tissue product. The non-crosslinked latex polymer creping composition does not negatively affect stiffness such that the products generally have a Stiffness Index less than about 5.0, such as from about 2.5 to about 5.0.
US12129600B2
The present invention provides rolled products, such as spirally wound rolls of bath tissue comprising a plurality of separably joined sheets, that may be repeatably and reliably dispensed by a user with a single hand. Single handed dispensing of the rolled products is facilitated by the web having a ratio of detach strength, typically having units of grams (g) to cross-machine direction (CD) tensile, having units of grams per 76.2 mm, of 0.65 or less, such as from about 0.10 to 0.65. In this manner rolled bath tissue products may have a CD tensile from about 400 to about 1,000 g/76.2 mm and a detach strength from about 100 to about 500 g.
US12129596B2
Silk coated and/or infused performance materials, apparel, and methods of preparing the same are disclosed herein. In some embodiments, silk performance apparel includes textiles, fabrics, consumer products, and other materials that are coated with aqueous solutions of pure silk fibroin-based protein fragments having low, medium, and/or high molecular weight in various ratios.
US12129595B2
A water repellent agent composition contains a compound represented by the following General Formula (1) and a silicone resin: wherein in Formula (1), R31 represents a monovalent hydrocarbon group having 4 to 30 carbon atoms, R32 represents a hydrogen, a monovalent hydrocarbon group having 1 to 30 carbon atoms, or an organic group represented by —R36—N(R37)—R38 (in the formula, R36 represents a divalent hydrocarbon group having 1 to 30 carbon atoms, and R37 and R38 each independently represent a hydrogen or a monovalent hydrocarbon group having 1 to 30 carbon atoms), R33 represents a divalent hydrocarbon group having 1 to 30 carbon atoms, R34 and R35 each independently represent a hydrogen or a monovalent hydrocarbon group having 1 to 30 carbon atoms, a represents an integer of 0 to 2, and when a is 2, the plurality of R32 and R33 each may be identical or different.
US12129589B2
A washing machine having a washed laundry/garment treatment system. The washing machine comprises a rotatable drum, a soap/laundry dispenser, a water supply flow valve, an ozone generator and a control panel for controlling operation of the rotatable drum, the soap/laundry dispenser, the water supply flow valve, and the ozone generator. The laundry/garment treatment system comprises a source of an additive/treating composition to be added a washing machine without any laundry/garments contained therein, and the source of the additive/treating composition is connected to the washing machine to supply a quantity of additive/treating composition thereto for mixing with water and formation of a treatment mixture. A circulating pump is connected to the washing machine for pumping the treatment mixture into a treatment holding tank. A mixture feed valve controls the flow of treatment mixture from the treatment holding tank back into the washing machine for treating the laundry/garments, following washing thereof.
US12129588B2
A washing machine appliance includes a wash basket that is rotatably mounted within a wash tub and that defines a wash chamber for receiving a load of clothes. A camera assembly is used to monitor articles for washing within the wash basket. Specifically, a controller of the washing machine appliance uses the camera assembly to obtain a reference image and one or more test images, which utilize image recognition to assess turn-over of the articles for washing during a given wash cycle. When turn-over performance is inadequate, a controller may adjust one or more operating parameters of the wash cycle to improve performance. Turn-over performance of the wash cycle is determined to be adequate once the image recognition process fails to find adequate correlation between the reference image and the test image a predetermined number of times.
US12129584B2
The operation information acquisition device includes the external detection device which is provided on the outer side of the main body frame of the sewing machine and detects the state change of the operating member that performs the periodic operation at the same cycle as the up-down movement operation of the sewing needle, the operation information acquisition device acquires operation information based on detection result of the external detection device. The operation information acquisition device can acquire the operation information such as the “number of stitches”, the “operating hours”, the “sewing speed”, and the “number of times of thread cutting”.
US12129583B2
The present invention relates to a method of producing a ribbon comprising bamboo fibers. The method comprises positioning the fibers on a conveyor and conveying the fibers in a transport direction, interconnecting the fibers by covering the fibers with thread and/or particles of a sticky material with at least one web forming device which is positioned above and/or below the conveyor and which ejects thread and/or particles. The formed thread and/or particles attaches to the fibers and forms a web which interconnects the fibers in order to form the ribbon and/or stitching the fibres together with at least one stitching device which is configured to stitch the individual fibers together in order to form the ribbon.
US12129572B2
There is provided a nitride semiconductor template, including: a substrate having a front surface and a back surface opposite to the front surface; a back side semiconductor layer provided on a back surface side of the substrate, comprising a polycrystalline group III nitride semiconductor, and having a linear expansion coefficient different from a linear expansion coefficient of the substrate; and a front side semiconductor layer provided on a front surface side of the substrate, comprising a monocrystalline group III nitride semiconductor, and having a linear expansion coefficient different from a linear expansion coefficient of the substrate, wherein a thickness of the front side semiconductor layer is a thickness exceeding a critical thickness at which cracks are generated in the front side semiconductor layer when only the front side semiconductor layer is formed without forming the back side semiconductor layer.
US12129567B2
Methods for producing flexible circuits can include creating treating a surface of the flexible circuit with at least one of an atmospheric plasma and a beam of ions. The atmospheric plasma is formed by directing a flow of gas between an electrode and the surface of the flexible circuit and generating a voltage between the electrode and the flexible circuit to create a plasma from the gas. A mean ion energy of the ions in the ion beam ranges from about 500 electron volts to about 1,500 electron volts.
US12129565B2
The present invention provides a pump device comprising a housing and a electrode device. The housing has an inlet and an outlet arranged at a side of the housing for allowing a first flow flowing into the housing. The electrode device is arranged in the housing, and comprises a rotating body having a fluid inlet, a plurality of first flow channels, at least one first electrode and at least one second electrode. The rotating body is driven to rotate thereby generating a negative pressure for drawing the first fluid into the plurality of first flow channels through the fluid inlet such that the first fluid is reacted with the first and second electrodes thereby generating micro bubbles and is exhausted from the plurality of first flow channels. The first flow having micro bubbles are exhausted from the housing through the outlet.
US12129563B2
The invention is related to a process for preparing a iodinating X-rays contrast agent. More specifically, it relates to a process for the preparation of N,N′-bis-(2,3-dihydroxypropyl)-5-hydroxy-2,4,6-triiodo-1,3-benzenedicarboxaniide (I) by electrochemical iodination of N,N′-(2,3-dihydroxypropyl)-5-hydroxy-1,3-benzenedicarboxamide (II) with molecular iodine (I2) which is in situ electrochemically generated from a source of iodide ions (I−). The iodide ions (I−) are obtained by the dissolution of hydrogen iodide (HI) or an alkali metal iodide in the reaction medium or produced during the reaction of N,N′-(2,3-dihydroxypropyl)-5-hydroxy-1,3-benzenedicarboxamide with I2. The invention also relates to the use of the intermediate compound of formula (I), obtained through the above electrochemical iodination of compound (II), in the preparation of N,N′-bis[2,3-dihydroxypropyl]-5(hydroxyacetyl)methylamino]-2,4,6-triiodo-1,3-benzenedicarboxamide (iomeprol).
US12129562B2
Systems and methods are provided for operating an electrolyzer. The systems and methods include operations comprising: forming an electrical series connection through the plurality of electrolytic cells; bypassing a first electrolytic cell using bypass circuitry included in a first bipolar plate to electrically remove the first electrolytic cell from the electrical series connection while maintaining flow of current through a second of electrolytic cell; monitoring one or more parameters of the plurality of electrolytic cells; and generating, based on the one or more parameters, a model representing operating conditions of the electrolytic cells on an individual electrolytic cell basis.
US12129561B2
A catalyst nanocomposite and methods of making the same. The catalyst nanocomposite includes a substrate; and a coating disposed on the substrate, the coating having a ruthenium and nitrogen co-doped carbon matrix. The coating may be melamine and formaldehyde and produced via pyrolizing the melamine and formaldehyde on a nanowire made of metals such as tellurium.
US12129554B2
A bi-layer protective coating for a metal component, the bi-layer protective coating comprising a bond coating that is metallurgically fused to a substrate of the metal component, wherein the bond coating comprises one or more rare metals and a top coating that is mechanically bonded to the bond coating, wherein the top coating comprises one or more metal oxides, or one or more metal carbides.
US12129538B2
A copper alloy for use as material for a casting mold or a casting mold component selected from the group consisting of mold plate, mold tube, casting wheel, casting drum, casting roller, and melting crucible. The copper alloy includes, in percent by weight (proportion by mass of the melt analysis in %): silver (Ag) 0.020-0.50, zirconium (Zr) 0.050-0.50, phosphorus (P) not more than 0.060, chromium (Cr) not more than 0.005, balance copper (Cu) and other alloying elements including unavoidable impurities, with a proportion of the other alloying elements being less than or equal to (≤) 0.50.
US12129535B2
Provided is a steel sheet for cans. A steel sheet for cans comprises: a chemical composition containing, in mass %, C: 0.010% or more and 0.130% or less, Si: 0.04% or less, Mn: 0.10% or more and 1.00% or less, P: 0.007% or more and 0.100% or less, S: 0.0005% or more and 0.0090% or less, Al: 0.001% or more and 0.100% or less, N: 0.0050% or less, Ti: 0.0050% or more and 0.1000% or less, and Cr: 0.08% or less, and satisfying a relationship 0.005≤(Ti*/48)/(C/12)≤0.700 where Ti*=Ti−1.5S, with a balance consisting of Fe and inevitable impurities; a microstructure in which a proportion of cementite in ferrite grains is 10% or less; and an upper yield strength of 550 MPa or more.
US12129533B2
Embodiments of an ultra-fine-grained, medium carbon steel are disclosed herein. In some embodiments, the ultra-fine grained steel can have high corrosion fatigue resistance, as well as high toughness and yield strength. The ultra-fine grained steels can be advantageous for use as sucker rods in oil wells having corrosive environments.
US12129525B2
An optimized Gamma-prime (γ′) strengthened austenitic transformation induced plasticity (TRIP) steel comprises a composition designed and processed such that the optimized γ′ strengthened austenitic TRIP steel meets property objectives comprising a yield strength of 896 MPa (130 ksi), and an austenite stability designed to have Msσ(sh)=−40° C., wherein Msσ(sh) is a temperature for shear, and wherein the property objectives are design specifications of the optimized γ′ strengthened austenitic TRIP steel. The optimized γ′ strengthened austenitic TRIP steel is Blastalloy TRIP 130.
US12129519B2
This present disclosure relates to systems, methods, and compositions useful for profiling T cell receptor (TCR) and B cell receptor (BCR) repertoire using next-generation sequencing (NGS) methods. The present disclosure also relates to systems and methods for diagnosing, treating, or predicting infection, disease, medical conditions, therapeutic outcome, or therapeutic efficacy based on the TCR/BCR profile data from a subject in need thereof.
US12129515B2
Techniques regarding screening for mutations using nanoscale deterministic arrays are provided. For example, one or more embodiments described herein can comprise a method, which can comprise cleaving a deoxyribonucleic acid segment hybridized with a molecular probe to form a sample fluid. The cleaving can occur at a first end and a second end of the molecular probe. Also, the cleaving can comprise a cleaving agent that targets base pair mismatches. The method can also comprise supplying the sample fluid to a nanoscale deterministic lateral displacement array to screen for a single nucleotide polymorphism.
US12129511B2
The present disclosure relates to methods, compositions, and kits for concentrating and purifying at least one target analyte from a clinical biological sample. In some embodiments, the methods involve one or more aqueous two-phase system (ATPS) compositions and at least one solid phase medium. Some embodiments provide a kit comprising one or more ATPS compositions, a binding buffer; and a solid phase medium. Other embodiments provide methods of treating cancers or infectious diseases in a patient in need thereof.
US12129509B2
Various methods, devices, and systems for determining the susceptibility of infectious agents to anti-infectives are disclosed herein. A method comprises introducing an inoculum solution comprising the infectious agent into a sample receiving space of a diagnostic device. The sample receiving space comprises a plurality of growth control wells devoid of the anti-infective and a plurality of active electrode wells comprising the anti-infective at differing concentrations. A water immiscible liquid can be introduced into the sample receiving space to seal the plurality of wells and the diagnostic device can be incubated for a period of time. The minimum inhibitory concentration (MIC) of the anti-infective on the infectious agent can be determined by monitoring and comparing one or more solution characteristics of the inoculum solution within the active electrode wells with the one or more solution characteristics of the inoculum solution with the growth control wells.
US12129506B2
This invention relates to metabolically engineered microorganism strains, such as bacterial strains, in which there is an increased utilization of malonyl-CoA for production of a fatty acid or fatty acid derived product, wherein the modified microorganism produces fatty acyl-CoA intermediates via a malonyl-CoA dependent but malonyl-ACP independent mechanism.
US12129503B2
Improving overall carbon capture specially carbon sequestration in soil and improving overall production yield of bio-derived chemical products and fuels by integrating microbial fermentation into nature-based solutions and natural climate solutions. Converting feedstock of biomass and optionally supplemental bio-derived material, wherein the biomass comprises harvested biodiverse above-ground plant material comprising at least about 2, 3, 5, 8, 10, 12, 15 or 20 different species of plants from an area of land wherein the biodiverse above-ground plant material is harvested no more than one, two, or three times in a 12-month period of time to one or more products. In certain aspects, also disclosed are to processes for producing desirable products, such as ethylene, from biodiverse biomass.
US12129500B2
Described herein are biological devices and methods for using the same to produce a polyactive carbohydrate. The biological devices include microbial cells transformed with a DNA construct containing genes for producing a chitin synthase, a chitosanase, and a chitin deacetylase. In some instances, the biological devices also include a gene for lipase. Methods for using the polyactive carbohydrate are also provided herein, including, but not limited to, enhancing the physiological properties of plants; medical applications; applications in the construction, materials science, and home goods industries; personal care, grooming, cosmetics, and oral care compositions containing the polyactive carbohydrate; methods for water decontamination; and the production of polyurethanes.
US12129498B2
Disclosed are variants of a cellulase having improved stability in the presence of a protease, and the use of such variants in laundry.
US12129497B2
The present invention relates to polypeptides, nucleotides encoding the polypeptide, as well as methods of producing the polypeptides. The present invention also relates to detergent compositions comprising polypeptides, a laundering method and the use of polypeptides.
US12129495B2
The present disclosure relates to engineered DNA polymerase polypeptides and compositions thereof, as well as polynucleotides encoding the engineered DNA polymerase polypeptides. The present disclosure also provides methods of using the engineered DNA polymerase polypeptides or compositions thereof for diagnostic and other purposes.
US12129494B2
The present invention provides engineered RNA polymerase variants and compositions comprising these variants. The present invention further provides engineered T7 RNA polymerase variants and compositions comprising these variants. These variants have been evolved for selective incorporation of the m7G(5′)ppp(5′)m7G cap analog over GTP at the initiation of in vitro transcription. The present invention also provides methods for selective capping of RNA transcripts.
US12129493B2
The present invention provides for a genetically modified host cell capable of producing an unnatural compound, such as terpenoid, comprising a P450 enzyme comprising an artificial cofactor, and the host cell is capable of uptaking the artificial cofactor by comprising a heterologous heme transport transmembrane protein, or homologue thereof.
US12129490B2
Methods for producing hepatocyte and/or cholangiocyte lineage cells from pluripotent stem cells, the method comprising (a) specifying the extended nodal agonist treated induced endodermal cell population to obtain a cell population comprising hepatocyte and/or cholangiocyte progenitors by contacting the extended nodal agonist treated induced endodermal cell population with specification media comprising a FGF agonist and a BMP4 agonist and/or active conjugates and/or fragments thereof; (b) inducing maturation, and optionally further lineage specification and/or expansion of the hepatocyte and/or cholangiocyte progenitors of the cell population to obtain a population comprising hepatocyte lineage cells such as hepatoblasts, hepatocytes and/or cholangiocytes, the inducing maturation step comprising generating aggregates of the cell population. Optionally, the method also comprises activating the cAMP pathway within the aggregates and forming co-aggregates.
US12129487B2
The present invention relates to a method for preparing lymphoid progenitors. The inventors took advantage of their original and relevant Warts, Hypogammaglobulinemia, Infections and Myelokathexis (WHIM) Syndrome (WS) model and the access to blood samples from five WS patients to investigate the impact of CXCR4 desensitization on BM and extra-medullary (i.e. splenic) hematopoiesis and hematopoietic stem and progenitor cells (HSPCs) recirculation. They developed, for the first time, an original in vitro system permitting to selectively expand HSPCs to obtain lymphoid progenitors by using an original cocktail of cytokines. In particular, the present invention relates to an in vitro method for preparing lymphoid progenitors by culturing HSPCs in an appropriate culture medium comprising an effective amount of a cocktail of cytokines consisting in SCF, IL-3, IL-6, IL-7, Flt-3, and CXCL12.
US12129476B2
The present disclosure presents improved analytical tools, systems and methods related to AADC viral vectors, including AADC potency assays for measuring and analyzing AADC expression potency (i.e. enzymatic activity) related to AADC vectors such as adeno-associated virus (AAV) AADC vectors.
US12129475B2
Disclosed herein are genetically modified plants having altered biological activity of 3-β-hydroxysteroid dehydrogenase/isomerase (GAME25), or 2-oxoglutarate-dependent dioxygenase (GAME31), or a combination thereof, wherein the genetically modified plants have an altered content of at least one cholesterol derived compound selected from the group including a steroidal alkaloid or a glycosylated derivative thereof and an unsaturated or saturated steroidal saponin or a glycoside derivative thereof. Further disclosed herein are genetically modified plants having altered expression of a gene encoding a 3-β-hydroxysteroid dehydrogenase/isomerase (GAME25), or a 2-oxoglutarate-dependent dioxygenase (GAME31), or a combination thereof, wherein the genetically modified plant has an altered content of at least one cholesterol derived compound selected from the group including a steroidal alkaloid or a glycosylated derivative thereof and an unsaturated or saturated steroidal saponin or a glycoside derivative thereof. Methods of producing these genetically modified plants are also disclosed.
US12129472B2
The present invention relates to genetically modified plants comprising a heterologous nucleic acid construct comprising a promoter sequence operably linked to a coding sequence encoding a gene product. The invention further relates to methods for producing such plants.
US12129469B2
Disclosed herein are short interfering nucleic acid (siNA) molecules comprising modified nucleotides and uses thereof. The siNA molecules may be double stranded and comprise modified nucleotides selected from 2′-O-methyl nucleotides and 2′-fluoro nucleotides. Further disclosed herein are siNA molecules comprising (a) a phosphorylation blocker, conjugated moiety, or 5′-stabilized end cap; and (b) a short interfering nucleic acid (siNA).
US12129460B2
Provided herein are methods of purifying messenger RNA (mRNA) by subjecting a preparation comprising in vitro synthesized mRNA to one or more steps of enzymatic digestion with a proteinase, optionally with a further oligo dT affinity chromatography step. Also provided are mRNA purified by the methods described herein.
US12129454B2
A method of making a non-fibrous laundry detergent sheet can include dispensing a microcapsule onto a precursor non-fibrous laundry detergent sheet, wherein the precursor non-fibrous laundry detergent sheet can include: (a) at least one surfactant; (b) at least one film former; and (c) a thickness ranging from 0.1 mm to 10 mm.
US12129453B2
A detergent composition includes a detersive surfactant and a graft polymer.
US12129448B2
Water-soluble unit dose article containing a laundry detergent composition containing a capsule having a core and a shell.
US12129437B2
The invention relates to the dissolution of amorphous dithiazine (a-DTZ) or polythioformaldehyde or other polymeric by-products of the treatment of hydrocarbon products (a-DZT) to remove them from surfaces. These are solids that build up on surfaces of processing plant and are resistant to most chemical treatment. The treatment requires treating the surface with an effective amount of a mercaptan or an amine. Surfactants to keep the dissolved a-DTZ or other components from redepositing elsewhere are also described, as is the use of hydrogen sulfide to add in removal by mercaptans.
US12129436B2
A process for separating one or more one-ring cycloparaffins and one or more multi-ring cycloparaffins from a hydrocarbon mixture is disclosed. The process comprises the steps of providing the hydrocarbon mixture; and contacting the hydrocarbon mixture with an adsorbent material comprising a metal organic framework to separate the one or more one-ring cycloparaffins and the one or more multi-ring cycloparaffins from the hydrocarbon mixture. The process is conducted in a liquid phase.
US12129435B2
The present invention relates to a system for producing synthetic fuels, in particular jet fuel (kerosene), gasoline and/or diesel, comprising: a) an apparatus for separately extracting carbon dioxide and water from ambient air, b) a synthesis gas production apparatus for producing a raw synthesis gas comprising carbon monoxide, hydrogen, carbon dioxide and water, the synthesis gas production apparatus having a supply line for carbon dioxide leading from the apparatus for separately extracting carbon dioxide and water from ambient air, a supply line for air and a supply line for water, c) a separating apparatus for separating carbon dioxide and water from the raw synthesis gas produced in the synthesis gas production apparatus, d) a Fischer-Tropsch apparatus for producing hydrocarbons by means of a Fischer-Tropsch process from the synthesis gas from which carbon dioxide and water were separated in the separating apparatus, e) a refining apparatus for refining the hydrocarbons produced in the Fischer-Tropsch apparatus into synthetic fuels, f) a desalination apparatus for desalinating water, the desalination apparatus having a water supply line from the apparatus for separately extracting carbon dioxide and water from ambient air and a water discharge line to the Fischer-Tropsch apparatus, and g) a water purification apparatus, which comprises a water supply line leading from the Fischer-Tropsch apparatus for purifying water produced therein, the system further comprising a pre-reformer for converting hydrocarbons other than methane into methane, carbon oxides, water and hydrogen and i) a water vapor supply line leading from the water purification apparatus to the pre-reformer, ii) a process gas supply line leading from the refining apparatus to the pre-reformer and/or a return gas line leading from the Fischer-Tropsch apparatus to the pre-reformer and iii) a circulation line leading from the pre-reformer to the supply line for water connected to the synthesis gas production apparatus.
US12129433B2
Methods and systems for treating a subterranean formation including kerogen are provided. An exemplary method includes forming a mixture including field water and oxygen, and injecting the mixture through a wellbore into the subterranean formation to oxidize at least a portion of the kerogen.
US12129413B2
Luminescent taggant compositions, luminescent materials that include luminescent taggants, and articles including luminescent taggants are provided herein. In an embodiment, a luminescent taggant composition includes a first luminescent taggant, a second luminescent taggant, and a third luminescent taggant. The first luminescent taggant includes a first emitting ion that produces a first emission in a first taggant emission band when exposed to excitation energy. The second luminescent taggant includes a second emitting ion that is different from the first emitting ion and that produces a second emission in a second taggant emission band that is different from the first taggant emission band when exposed to excitation energy. The first luminescent taggant is substantially free of the second emitting ion and the second luminescent taggant is substantially free of the first emitting ion. The third luminescent taggant includes the first emitting ion and the second emitting ion.
US12129412B2
A curable silicone composition is provided. The curable silicone composition comprises a cadmium-free quantum dot in an amount of from about 0.01 to about 10 mass % of the composition, wherein the composition can be cured by a hydrosilylation reaction and has at least about 10 mol % of aryl groups in all silicon atom-bonded organic groups. The curable silicone composition exhibits excellent dispersibility of the quantum dot, and cures to form a cured product exhibiting excellent color conversion efficiency.
US12129411B2
An electrically conductive bonding tape includes a conductive self-supporting first layer conductive in each of three mutually orthogonal directions and including conductive opposing first and second major surfaces, an conductive second layer coated on the first major surface of the self-supporting first layer and having at least 60% by weight of nickel, the second layer having an exposed major surface facing away from the first major surface of the self-supporting first layer and exposing at least some of the nickel in the second layer, and a conductive adhesive third layer bonded to the second major surface of the self-supporting first layer opposite the second layer. The adhesive third layer is conductive in at least one of the three mutually orthogonal directions and includes a plurality of conductive elements dispersed in an insulative material, at least some of the conductive elements physically contacting the self-supporting first layer.
US12129403B2
A polishing composition is for polishing a resin, and includes alumina abrasive grains, a dispersant, and water. A ratio between a primary average particle size of alumina particles in the alumina abrasive grains and an average particle size of the alumina particles measured by dynamic light scattering is 1:6.0 to 1:100.
US12129400B1
Provided is a method for preparing an alkaline red mud coating for preventing marine organism attachment, including: (1) mixing stearic acid and absolute ethanol by stirring to obtain a mixed solution; (2) mixing the mixed solution and a red mud powder to obtain a mixture, and drying the mixture to obtain a modified hydrophobic red mud powder; (3) adding benzyl glycidyl ether into an epoxy resin and conducting dispersion to be uniform to obtain a mixed system, adding the modified hydrophobic red mud powder into the mixed system, continuing the dispersion to be uniform to obtain a blend, and grinding the blend to obtain an antifouling coating material; and (4) during use, mixing the antifouling coating material with a polyamide curing agent to obtain a mixture system, and applying the mixture system onto a surface of building to form the alkaline red mud coating for preventing marine organism attachment.
US12129393B2
The present invention relates to a composition comprising a binder comprising one or more siloxane polymers, silicone resins, silicone based elastomers, and mixtures thereof, wherein said binder optionally comprises one or more cross-linker components comprising a silane and/or a siloxane containing silicon-bonded hydrolysable groups; and a hydrophilic powder and/or gel selected from one or more amorphous, porous hydrophilic silica (s) having a thermal conductivity at 20° C. and atmospheric pressure of 0.001 to 0.15 W/m·K and a surface area (SBET) of between 200 and 1500 m2/g, one or more hydrophilic aerogel (s) and mixtures thereof, wherein the binder is a solution, an emulsion, or a dispersion in water. The invention also relates to the use of the composition as or in thermally or acoustically insulating materials and to coated substrates, products and articles made by using the composition.
US12129389B2
Embodiments of the invention relate to ink compositions suitable for applications in the printing industry, for example continuous inkjet printing, including ultra-high speed continuous inkjet printing. The ink compositions use volatile C5 ketone (pentanone) solvents (e.g., 2-pentanone, 3-pentanone, or 3-methyl-2-butanone) as a major solvent or the only solvent, and also include a binder resin and a colorant, but preferably contain substantially no acetone, methanol, or methyl ethyl ketone, or other solvents listed on the Japan ISHL class II organic solvents list. Preferred ink compositions can contain up to 30% ethanol, n-propanol, or other solvents not listed on the Japan ISHL class II organic solvents list, but preferably contain substantially no ethanol.
US12129378B2
A composition is provided that restores and protects substrates to which it is applied including trim and tires on vehicles. The composition forms a high adhesion high cohesion film that protects the underlying substrate from the adverse effects of ultra violet (UV) rays, heat, rain, snow, and other environmental contaminants. A process of applying the same is also provided.
US12129377B2
A moisture-curing polyurethane composition having a content of monomeric diisocyanates of at most 0.1 wt %, containing: at least one isocyanate-group-containing polyurethane polymer having a content of monomeric diisocyanates of at most 0.5 wt %, obtained from reaction of at least one monomeric diisocyanate with at least one polyether polyol at a NCO/OH ratio of at least 3/1 and subsequent removal of a large part of monomeric diisocyanates by way of a suitable separating method; and at least one polyether having blocked hydroxyl groups and free of isocyanate groups, as a plasticizer. Moisture-curing polyurethane composition is highly storage-stable when moisture is excluded, can be safely handled without special safety precautions, can be sold without hazard label, can be well processed, has long open time and has fast curing to form elastic material of high strength and extensibility, high cold flexibility, good adhesion properties and high stability with respect to heat and moisture.
US12129373B2
Disclosed herein is a self-healing asphalt binder composition comprising i) an asphalt binder, ii) an oxetane substituted polysaccharide, and iii) a polyurethane, as well as asphalts comprising said self-healing asphalt binder and an asphalt mixture. Also disclosed are methods of making the self-healing asphalt binder.
US12129372B2
Powder particulates comprising a water-soluble polymer and production thereof by melt emulsification
Powder particulates comprising a water-soluble polymer may be formed by melt emulsification. Compositions comprising powder particulates may comprise a plurality of particulates comprising a water-soluble polymer and a plurality of nanoparticles, the water-soluble polymer defining at least an outer surface of the particulates and at least a majority of the plurality of nanoparticles being disposed upon the outer surface.
US12129370B2
A rubber composition is disclosed and comprises a rubber matrix and essential components. The rubber matrix comprises, based on 100 parts by weight of the rubber matrix, A parts of a branched polyethylene, wherein 0
US12129361B2
The present disclosure discloses methods for preparing a composite film based on reduced graphene oxide, cellulose nanocrystals, and cellulose nanofibers. The method mainly includes: 1. preparing a suspension mixed with graphite oxide and cellulose; 2. centrifuging the suspension obtained in the step (1) and washing the sediment after centrifuging with deionized water to obtain a solution, homogenizing the solution in a high-pressure homogenizer to obtain a suspension mixed with graphene oxide, cellulose nanocrystals, and cellulose nanofibers; and 3. drying the suspension mixed with graphene oxide, cellulose nanocrystals, and cellulose nanofibers in a petri dish, and soaking a dried film in a hydroiodic acid solution; and washing the soaked film with deionized water to obtain the composite film of reduced graphene oxide, cellulose nanocrystals, and cellulose nanofibers. The composite film obtained has a higher specific capacitance and a better cycle stability than pure reduced graphene oxide obtained under a same preparation condition.
US12129356B2
A crystalline pigment or colorant composition having high color intensity and/or low sugar content, and methods and processes of preparation. The composition may comprise purified fruit and/or vegetable color juices.
US12129353B2
Disclosed are cellulose-based flexible gels containing cellulose nanorods, ribbons, fibers, and the like, and cellulose-enabled inorganic or polymeric composites, wherein the gels have tunable optical, heat transfer, and stiffness properties. The disclosed gels are in the form of hydrogels, organogels, liquid-crystal (LC) gels, and aerogels, depending on the solvents in the gels.
US12129348B2
A hard coating film comprising a base layer including: a polymer binder resin; first inorganic particles dispersed in the polymer binder resin and having an average particle size of 5 nm or more and less than 70 nm; and second inorganic particles which are dispersed in the polymer binder resin and have an average particle size of 70 nm to 150 nm is provided.
US12129343B2
A method for purifying a contaminated reclaimed HDPE is provided. The method comprises obtaining the contaminated reclaimed HDPE, extracting it with a solvent to produce an extracted contaminated reclaimed HDPE, and then dissolving it in the solvent to produce a first suspension comprising dissolved HDPE and suspended contaminants. The first suspension is settled to produce a second suspension comprising dissolved HDPE and suspended remaining contaminants, and the second suspension is purified by contacting it with solid media to produce a third suspension comprising purer HDPE. Finally, the purer HDPE is separated from the third suspension and it has natural-like optical properties.
US12129342B2
Disclosed herein are processes for ethanol production from a lignocellulosic feedstock. These processes provide DMR of lignocellulosic biomass comprising two-stage deacetylation followed by mechanical refining so as to increase fermentable sugar yield while reducing hydrolytic enzyme loading requirements.
US12129340B2
The present invention relates to a procedure in which a functionalized polysiloxane is synthesized in the presence of a platinum catalyst, and halogen-functionalized polysiloxanes obtained according to the procedure. The procedure is defined herein by reacting a) at least one polysiloxane comprising at least one hydrogen atom bonded to a silicon atom; b) at least one heterocyclic compound; and c) at least one halogen-containing compound, wherein the reaction is catalyzed by at least one platinum catalyst. The synthetic pathway is described as a halosilation reaction in which a heterocyclic molecule is ring-opened in the presence of a platinum catalyst and a halogen source, resulting in a formal insertion of the opened heterocycle into the SiH bond. On the final product, the heteroatom of the former heterocycle is bonded to the silicon atom from the former hydrosiloxane moiety while the halogen is bonded to the last carbon atom of the opened chain.
US12129334B2
A modified polyurethane carrier substrate is provided. The modified polyurethane carrier substrate is formed from a modified polyurethane. The modified polyurethane includes a soft segment and a hard segment. The soft segment is formed from a polyol. The hard segment is formed from diisocyanate and a chain extender. The chain extender is dianhydride. A common logarithm of a ratio of a storage modulus of the modified polyurethane carrier substrate at −30° C. to a storage modulus of the modified polyurethane carrier substrate at 150° C. ranges from 0.40 to 1.30.
US12129332B2
The invention relates to a self-supporting polymer film comprising a thermoplastic polymer, a ketone, and at least one organic photochromic molecule comprising a chromophore, wherein preferably the at least one organic photochromic molecule comprising a chromophore is evenly distributed in the self-supporting polymer film. A typical self-supporting polymer film of the invention is a self-supporting photochromic aliphatic thermoplastic polyurethane film imbibed with a ketone such as acetone and cyclohexanone, further comprising one or more of a diarylethene, a spirooxazine and a naphthopyran, preferably a polydialkylsiloxane-substituted naphthopyran. The invention also relates to a method for the manufacturing of such a self-supporting polymer film of the invention, and to the use of such a self-supporting polymer film in the manufacturing of an article. Furthermore, the invention relates to an article comprising a self-supporting polymer film of the invention.
US12129331B2
The present disclosure provides soft block copolymer segments of Formula 1 for thermoplastic polyurethane or polyurethaneurea elastomer materials and their reaction products with divalent compounds, such as diisocyanates, chain extenders and optional additional polyols or polyamines. Also disclosed herein are methods for the production of the soft block copolymer segments, and possible applications of these materials in the formation of biomaterials for articles including medical devices such as implants, heart valves and drug delivery devices.
US12129323B2
Methods for forming latexes are provided. In an embodiment, such a method comprises adding a monomer emulsion comprising water, a monomer, an acidic monomer, a hydrophilic monomer, a difunctional monomer, a first reactive surfactant, and a chain transfer agent, to a reactive surfactant solution comprising water, a second reactive surfactant, and an initiator, at a feed rate over a period of time so that monomers of the monomer emulsion undergo polymerization reactions to form resin particles in a latex. The reactive surfactant solution does not comprise monomers other than the second reactive surfactant, the reactive surfactant solution does not comprise a resin seed, and the monomer emulsion does not comprise the resin seed. The latex is characterized by a viscosity in a range of from about 10 cP to about 100 cP as measured at a solid content of about 30% and at room temperature. The latexes are also provided.
US12129319B2
The invention relates to an efficient process for the preparation of isoolefin polymers such as polyisobutene or butyl rubber by polymerization of isobutene and optionally further monomers in the presence of an initiator system comprising at least one boron or aluminium compound and at least one tertiary alkyl ether.
US12129318B2
The present invention relates to a method for preparing a vinyl chloride-based polymer, including: bulk polymerizing a vinyl chloride-based monomer in a polymerization reactor to prepare a vinyl chloride-based polymer; and adding water and vapor to the polymerization reactor, and heating to remove an unreacted vinyl chloride-based monomer, wherein an addition amount of the water is 0.500 to 5.000 parts by weight based on 100 parts by weight of the vinyl chloride-based polymer.
US12129304B2
The present disclosure relates to administration speed of obinutuzumab.
US12129299B2
This invention relates to anti-CTLA-4 antibody compositions that bind to the human CTLA-4 molecule, and the use of the compositions in cancer immunotherapy and for reducing autoimmune side effects compared to other immunotherapeutic agents.
US12129294B2
The present invention is directed to methods for treating diseases in which IL-13 activity is detrimental, including eosinophilic esophagitis (EoE) and asthma, by administering to a subject in need of such treatment, a composition containing an interleukin-13 (IL-13) antibody, or an antigen binding fragment, thereof.
US12129292B2
Presented here are methods for producing a recombinant anti-TNF antibody having a heavy chain (HC) comprising SEQ ID NO:38 and a light chain (LC) comprising SEQ ID NO:37 and compositions comprising the recombinant anti-TNF antibody.
US12129290B2
Disclosed herein are monoclonal antibodies that specifically bind to human mature Factor D and that do not bind to human Pro-Factor D, monoclonal antibodies that specifically bind to human Pro-Factor D and do not bind to human mature Factor D, and monoclonal antibodies that bind to both human mature Factor D and human Pro-Factor D. Also disclosed are methods of using the monoclonal antibodies, and compositions comprising the same, for detection of the mature and/or the pro-form of Factor D in biological samples, to determine the status of the Alternative Pathway of Complement (APC) in a mammalian subject, or to determine the status of Factor D after treatment with a MASP-3 inhibitory agent which inhibits the conversion of Pro-Factor D to mature Factor D.
US12129289B2
The present invention relates to a class of monoclonal antibody that specifically binds the phosphorylated serine 396 residue on pathological hyperphosphorylated (PHF) tau (pS396) with improved affinity, as well as to methods of using these molecules and their tau binding fragments in the treatment of Alzheimer's disease and other tauopathies.
US12129286B2
This disclosure relates to, inter alia, cells expressing both a chimeric antigen receptor (CAR) and membrane bound IL-12 and the use of these cells to target and treat cancers (e.g., solid tumors and cancers expressing CD19, CD22, BCMA, PSCA, HER2, TAG-72, and PSCA). The disclosure also relates to cells expressing a membrane bound IL-12.
US12129285B2
A method of treating a neurodegenerative disease in a subject includes administering to the subject a therapeutically effective amount of a TDP-43 mitochondrial localization inhibitor.
US12129275B2
Compounds are provided according to Formula (I) and pharmaceutically acceptable salts thereof, wherein Z is a group of the formula (i), (ii), (iii), (iv), or (v), and wherein L1, L2, L3, X1, X2, Y, Rz4, Rz5, Rz6, n, R1, R2, R3a, R3b, R4a, R4b, R6a, R6b, R7a, R7b, R11a, R11b, R14, R17, R19, R20, R23a, R23b, and R24 are as defined herein, and pharmaceutical compositions thereof. Compounds of the present invention are contemplated useful for the prevention and treatment of a variety of CNS-related conditions in mammals.
US12129266B2
The present disclosure provides a substituted pyrazolo[1,5-a]pyridine compound, a composition including the same, and a use thereof. The substituted pyrazolo[1,5-a]pyridine compounds is a compound represented by formula (I) or the tautomers, stereoisomers, prodrugs, crystal forms, pharmaceutically acceptable salts, hydrates or solvates thereof. The compound of the present disclosure and composition thereof are useful for treating RET kinase-mediated diseases or conditions and have more excellent pharmacokinetic properties.
US12129263B2
The present disclosure relates generally to compounds and compositions, intermediates, processes for their preparation, and their use as kinase inhibitors.
US12129262B2
The disclosure is directed to compounds of Formula I pharmaceutical compositions comprising compounds of Formula I, as well as methods of their use and preparation, are also described.
US12129257B1
Novel imidazo[1,2-a]pyrazines, a method of synthesizing said compounds, a pharmaceutical composition comprising said compounds and a suitable carrier, and a method of using the compounds. The imidazo[1,2-a]pyrazine compounds, identified as CK2 inhibitors, are useful as anticancer and/or antitumor agents, and as agents for treating other kinase-associated conditions including inflammation, pain, and certain immunological disorders, and other types of diseases such as diabetes, viral infection, neurodegenerative diseases.
US12129256B2
A compound having the structure: or a pharmaceutically acceptable salt thereof, or a pharmaceutically acceptable solvate of said compound or pharmaceutically acceptable salt, wherein A, A′ and A″ are independently O, C═O, C—R′ or N—R″, where R′ and R″ may independently be H, amino, —NR7COR6, COR6, —CONR7R8, C1-C6 alkyl, or hydroxy(C1-C6 alkyl), and R″ may be present or absent, and is present where the rules of valency permit, and where not more than one of A, A′ and A″ is O or C═O; R0 and R are independently H, Br, Cl, F, or C1-C6 alkyl; R1 is H, C1-C6 alkyl, or hydroxy(C1-C6 alkyl); R2 is selected from the group consisting of H, C1-C6 alkyl, C1-C6 alkoxy, hydroxy(C1-C6 alkyl), phenyl(C1-C6 alkyl), formyl, heteroaryl, heterocyclic, —COR6, —OCOR6, —COOR6, —NR7COR6, —CONR7R8, and —(CH2)n—W, where W is cyano, hydroxy, C3-C8 cycloalkyl, —SO2NR7R8, and —SO2—R9, where R9 is C1-C6 alkyl, C3-C8 cycloalkyl, heteroaryl, or heterocyclic; wherein each of said alkyl, cycloalkyl, heterocyclic, or heteroaryl may be unsubstituted or substituted by halo, cyano, hydroxy, or C1-C6 alkyl; X is C—R3 or N, where R3 may be H or C1-C6 alkyl; R4 and R5 are independently H, amino, C1-C6 alkyl, or hydroxy(C1-C6 alkyl); R6, R7 and R8 are each independently H, C1-C6 alkyl, C1-C4 alkoxy(C1-C6 alkyl), or C3-C8 cycloalkyl, said C1-C6 alkyl is optionally substituted by halo, CN or hydroxy; or, R7 and R8 together with the atom bonded thereto form a 5- or 6-membered ring, said ring being optionally substituted by halo, hydroxy, CN, or C1-C6 alkyl; and, n is 0, 1, 2 or 3. Also provided are methods of treatment as Janus Kinase inhibitors and pharmaceutical compositions containing the compounds of the invention and combinations thereof with other therapeutic agents.
US12129253B2
A first object of the present invention is to provide a method for producing a cyclic imide compound with high yield and high purity. A second object of the present invention is to provide a composition that can be used in the method for producing a cyclic imide compound with high yield and high purity. A third object of the present invention is to provide an intermediate compound that can be used in the method for producing a cyclic imide compound with high yield and high purity. The method for producing a cyclic imide compound according to the present invention includes reacting a compound represented by formula (1) below with at least one amine compound to obtain a compound represented by formula (2) below.
US12129252B1
Novel pyrrolo[2,3-c][2,6]naphthyridine-8-carboxylic acid compounds, a method of synthesizing said compounds, a pharmaceutical composition comprising said compounds and a suitable carrier, and a method of using the compounds. The pyrrolo[2,3-c][2,6]naphthyridine-8-carboxylic acid compounds, identified as CK2 inhibitors, are useful as anticancer and/or antitumor agents, and as agents for treating other kinase-associated conditions including inflammation, pain, and certain immunological disorders, and other types of diseases such as diabetes, viral infection, neurodegenerative diseases.
US12129250B2
The invention provides a novel class of therapeutic agents that are safe and effective TYK2 inhibitors and pharmaceutical compositions of these compounds and methods of preparation and use thereof against various TYK2-mediated diseases and disorders.
US12129247B2
A compound of formula (I) where R1, R2, X, Y, n, m, R3, R4, R5, R6 and R7 are as defined herein, for use in the prophylaxis or treatment of a central and peripheral nervous system disorder, wherein the compound of formula (I) is administered prior to sleep, before bedtime or at bedtime.
US12129245B2
Disclosed is crystalline Form E of 6-(cyclopropanecarboxamido)-4-((2-methoxy-3-(1-methyl-1H-1,2,4-triazol-3-yl)phenyl) amino)-N-(methyl-d3)pyridazine-3-carboxamide. Form E is a neat crystalline form. Characterization data for Form E are disclosed.
US12129240B2
Provided are a novel sulfonium salt having high photosensitivity to g-rays or h-rays; a novel photoacid generator containing a sulfonium salt that has high photosensitivity to g-rays or h-rays, has high solubility in solvents and cationically polymerizable compounds such as epoxy compounds, and has an excellent storage stability in compositions containing the cationically polymerizable compounds; and the like. The present invention relates to a sulfonium salt represented by the formula (1), a photoacid generator containing the sulfonium salt, and the like.
US12129237B2
Provided herein are Diaminopyrimidine Compounds having the following structures: wherein R1, R2, R3, and R4 are as defined herein, compositions comprising an effective amount of a Diaminopyrimidine Compound, and methods for treating or preventing liver fibrotic disorders or a condition treatable or preventable by inhibition of a JNK pathway.
US12129234B1
The present disclosure relates to a crystalline N-ethyl-2-(5-fluoro-1H-indol-3-yl)-N-methylethan-1-amine salt selected from crystalline N-ethyl-2-(5-fluoro-1H-indol-3-yl)-N-methylethan-1-amine monophosphate, crystalline N-ethyl-2-(5-fluoro-1H-indol-3-yl)-N-methylethan-1-amine mono-p-tosylate, crystalline N-ethyl-2-(5-fluoro-1H-indol-3-yl)-N-methylethan-1-amine hemimalate, and crystalline N-ethyl-2-(5-fluoro-1H-indol-3-yl)-N-methylethan-1-amine monosuccinate, pharmaceutical compositions comprising same, and uses thereof for treating mood disorders.
US12129230B2
Provided is a dialkyl carbonate production method that enables a dialkyl carbonate to be produced in a simple manner and in a short reaction time and enables easy processing of by-products. This dialkyl carbonate production method involves generation reaction of a carbonate ester through reaction between carbon dioxide and an alcohol represented by formula (1), wherein the generation reaction of a carbonate ester is performed in the presence of a carbodiimide compound represented by formula (2) (R1-R3 in the formula are as described in the description of the present application). [Chemical formula 1] R1—OH (1) [Chemical formula 2] R2—N═C═N—R3 (2)
US12129226B2
Processes for converting ethanol and syngas (CO and H2) to isobutanol are disclosed. Syngas and ethanol are reacted in the first reaction zone in the presence of a first heterogeneous catalyst to produce a first reactor effluent comprising a first mixture of alcohols. The first reactor effluent is reacted a second reaction zone in the presence of a second heterogeneous catalyst to produce a second reactor effluent comprising a second mixture of alcohols. The second reactor effluent is separated into an overhead gas stream and a liquid bottom stream. The liquid bottom stream is separated into at least a C1-2 stream, a C3 stream, and a C4+ stream. The isobutanol is recovered from the C4+ stream.
US12129225B2
Some variations provide a process for producing mixed alcohols, comprising: purifying a biogas feedstock to generate a renewable natural gas stream comprising methane; introducing the renewable natural gas stream into a methane-to-syngas unit operated at effective conditions to convert the methane to a first syngas stream containing at least H2, CO, and CO2; purifying the first syngas stream, including separating the CO2 from the first syngas stream, and optionally separating some of the H2 from the first syngas stream, thereby generating a clean syngas stream; introducing the clean syngas stream into a mixed-alcohol reactor operated at effective alcohol synthesis conditions with an alcohol-synthesis catalyst, thereby generating mixed alcohols; and purifying the mixed alcohols to generate a mixed-alcohol product. The mixed-alcohol product may be blended with a hydrocarbon fuel, such as gasoline, to produce a blended fuel. The blended fuel has significantly lower carbon intensity than the base hydrocarbon fuel.
US12129221B2
The disclosed compounds inhibit cellular necrosis, and include corresponding sulfonamides, prodrugs and pharmaceutically acceptable salts, hydrates and stereoisomers thereof. The compounds are employed in pharmaceutical compositions, and methods of making and use, including treating a person in need thereof with an effective amount of the compound or composition, and detecting a resultant improvement in the person's health or condition.
US12129219B2
Provided is a calcium-based catalyst and a method for catalytically synthesizing an alkanolamide surfactant thereof. The method includes the preparation of the catalyst, and then catalyzing a reaction of fat and oil, or fatty acid ester and alkanolamine with the catalyst to synthesize a light colored alkanolamide surfactant with less free alkanolamine. The catalyst has a slow release feature, so that late in the reaction, the catalyst still has relatively high catalytic reactivity, guaranteeing a high conversion rate of the alkanolamine into the alkanolamide surfactant, the, product residual quantity of alkanolamine is low, while the risk of nitrosamine production due to product residual alkanolamine is greatly lowered. Due to catalyst slow release control, the early reaction period speed is greatly reduced, thereby avoiding a deepened product color caused by poor heat transfer due to an early reaction period being excessively fast.
US12129215B2
Described herein are agricultural compositions comprising an adduct of urea comprising: urea; and an inorganic salt; wherein the adduct has an average particle size ranging from about 0.1 microns to about 10 microns.
US12129208B2
Green ceramic batch mixtures include: at least one inorganic batch component, preferably cordierite; at least one binder, preferably polyisoprene, poly(vinyl formal), poly(vinyl methyl ether), polybutadiene carboxy terminated; and an inverse emulsion having a continuous phase, an aqueous dispersed phase, and at least one emulsifier, preferably at least one functionalized silicone compound having at least one functional group chosen from a hydroxyl group, a carboxyl group, hydroxyl-terminated ethylene oxide groups.
US12129202B2
A panel is disclosed. The panel has an exposed surface and a plurality of liquid-repelling elements disposed directly on the exposed surface in a discontinuous pattern. The liquid-repelling elements include a non-hydrophobic material.
US12129197B2
An apparatus is provided for producing thin glass ribbons from molten glass. The apparatus includes a drawing tank, a direct heater, and an indirect heater. The drawing tank has a lower elongated nozzle opening through which the molten glass can exit downwards. The direct heater has one or more heating circuits operable to heat the drawing tank in a first heating zone. The direct heater has a power source for each on the heating circuits. Each heating circuit has connections to connected to a wall of the drawing tank so that current from the power source flows through at least a portion of the wall and heats the wall. Each heating circuit also includes current-carrying portions of the wall. The indirect heater has one or more heating elements to heat the drawing tank in a second heating zone.
US12129189B2
The present disclosure includes systems and methods for enhancing evaporation rates of a fluid, such as fluid including dissolved solids (e.g., a wastewater pond). In one example, a system includes a pump configured to pressurize air and an agitation assembly fluidly coupled to the pump, where the agitation assembly is configured to emit an air stream that impacts a top surface of the fluid body to generate droplets.
US12129185B2
Disclosed is an α-phase nickel hydroxide and a preparation method and use thereof. The method for preparing an α-phase nickel hydroxide comprises the following steps: subjecting a biomass calcium source to a calcination to obtain a porous calcium oxide; under a protective atmosphere, mixing the porous calcium oxide with a first methanol-ethanol solvent to obtain a calcium oxide heterogeneous solution; under a protective atmosphere, mixing the calcium oxide heterogeneous solution with a nickel source homogeneous solution to obtain a mixture, and subjecting the mixture to a coprecipitation to obtain a nickel calcium hydroxide precursor, wherein the nickel source homogeneous solution is prepared with a nickel source containing crystal water as a solute and a second methanol-ethanol solvent as a solvent; and subjecting the nickel calcium hydroxide precursor to a calcium hydroxide removal treatment to obtain the α-phase nickel hydroxide.
US12129183B2
A method for preparing a basic copper carbonate is provided. The method includes: mixing a copper hydroxide with water to obtain a precursor slurry; adding an accelerator to the precursor slurry and mixing the two to obtain a first mixture; introducing gaseous carbon dioxide into the first mixture for reaction whereby obtaining a crude basic copper carbonate; and purifying the crude basic copper carbonate whereby obtaining the basic copper carbonate. The accelerator is at least one selected from the group consisting of an ammonia water and an ammonium salt.
US12129176B2
Systems and methods for converting metal oxide to metal using metal carbide as an intermediate, include: reacting the metal oxide with carbon to produce the metal carbide, wherein the metal carbide is in a form of powder or pellets; and subjecting the metal carbide produced from the metal oxide and the carbon to electrolysis in an electrorefiner to produce and purify the metal.
US12129169B2
Provided is a semi-finished product of an electronic device, including a substrate, a sensing module, and a lid. The substrate has a first surface and a second surface opposite to each other. The sensing module is disposed on the first surface. The lid is disposed on the first surface and forms a first cavity together with the substrate. An electronic device is also provided.
US12129167B1
A microelectromechanical systems (MEMS) inertial sensing device having a large proof mass with interlocking tabs is disclosed. The interlocking tabs limit motion of the proof mass when subjected to large inertial forces. The interlocking tabs are formed around the periphery of the proof mass and interact with corresponding interlocking tabs formed in a frame to which the proof mass is tethered. The motion of the proof mass is limited by the interlocking tabs, which are formed during MEMS fabrication of the inertial sensing device rather than as part of the packaging process. With a large proof mass, the inertial sensing device can provide high sensitivity in low inertial force environments while the interlocking tabs protect the device when subjected to high inertial forces.
US12129164B2
An integrated front-of-house and back-of-house restaurant operations system integrates automated and manual restaurant operations into an order-based system. The system interfaces with disparate devices and systems to provide order-based monitoring and control of operations within an establishment.
US12129135B2
A transportation device for fruit and vegetable picking in a solar greenhouse is provided, which may include a guide rail, a moving mechanism and a picking box. The guide rail is horizontally fixed on side surfaces of multiple supporting columns in the solar greenhouse, an upper side and a lower side of the guide rail are respectively provided with horizontally extended sliding grooves, and a top of the moving mechanism is slidably connected to the guide rail through the sliding grooves, and the picking box is hung at a bottom of the moving mechanism. The transportation device is used to hang the picking box at a bottom of the moving mechanism, so that the moving mechanism can carry the picking box to move along the sliding grooves to transport the picking box to a destination, thereby saving time, saving labor and reducing a labor cost.
US12129134B2
A temperature control docking system (TCDS) is configured for providing temperature controlled air for circulation within one or more freight trailers. The freight trailers are engaged with corresponding control docks of the TCDS, each control dock additionally defining a docking door configured between a closed configuration and an open configuration. The docking door separates the interior of the TCDS from an exterior thereof (and from the freight trailer). Upon engaging the freight trailer with the control dock, the docking door is configured to an open configuration, and a temperature maintenance unit positioned within the interior of the TCDS and corresponding with the control dock provides temperature controlled air for circulation within the interior of the freight trailer so as to maintain a desired temperature within the freight trailer.
US12129132B2
A robotic singulation system is disclosed. In various embodiments, sensor data image data associated with a plurality of items present in a workspace is received. The sensor data is used to determine and implement a plan to autonomously operate a robotic structure to pick one or more items from the workspace and place each item singly in a corresponding location in a singulation conveyance structure. The plan includes performing an active measure to change or adapt to a detected state or condition associated with one or more items in the workspace.
US12129125B2
A storage, retrieval and processing system for processing objects is disclosed that includes a plurality of bins including objects to be distributed by the storage, retrieval and processing system, the plurality of bins being provided on an input conveyance system, a programmable motion device that includes an end effector for grasping and moving any of the objects, a perception system for providing perception data regarding a selected object that is presented to the perception system by the programmable motion device, and a routing conveyance system for receiving the selected object, and for moving the selected object in each of horizontal and vertical directions toward a destination container responsive to the perception data, the destination container being provided among a plurality of destination containers in a row that are provided as a set on a destination conveyance system.
US12129124B2
A conveyor for transporting and elevating articles and a method and system for conveying articles up inclines is provided. The conveyor has a conveyor belt and a plurality of support elements extending outward from the article-conveying surface of the conveyor belt advancing upward along the incline. The conveyor may be positioned at an inclined angle relative to the horizontal ground, i.e., between about 5° and 85° or the conveyor can be substantially vertical, i.e., about 90° relative to the horizontal ground. The support elements prevent conveyed articles from sliding down the conveyor belt on the inclined conveyor and carry and hold articles on substantially vertical conveyors. The article-conveying surface of the conveyor belt may provide a low-friction retention surface to articles leaning away from the conveyor belt on the incline.
US12129119B2
A ripening schedule for produce is created and the ripening schedule when implemented at a ripening chamber is effective to control the environmental conditions and the time spent in the ripening chamber by the produce in order to conform ripening conditions of the produce to the target shipping date. The ripening schedule is applied to control ripening conditions in the ripening chamber.
US12129105B2
The present disclosure relates to a package for a delivery system. The package includes a container and a lid hingedly connected to the container about a hinge line, and an inner frame received in the container. The inner frame has a portion that extends from the container which is received in the lid when the lid is closed. The package further includes a raised seal line that is formed on the portion of the inner frame and/or on an inner surface of the lid. The raised seal line is configured to minimize a gap between the portion of the inner frame and the inner surface of the lid when the lid is closed. The present disclosure also relates to a method of manufacturing the package.
US12129103B1
The present invention provides an apparatus for storing, measuring and dispensing a desired quantity of semi-solid food, the apparatus being based on piston base with peripheral contact inside a rigid circular sleeve configured for storing at least 600 cubic centimeters of a semi-solid food substance k above the piston base inside the rigid circular cylinder. After filling, the apparatus is configured to enable pushing food material out the top of the cylinder toward the arm on a graduated rod until the desired preset quantity is above the top rim of the cylinder. That material can then be sliced of at the rim level for use and an included lid installed on the top rim of the circular cylinder to cover the remaining food material.
US12129098B2
Described are ovenable or cook-in packages that maintain a hermetic seal. The packages include an information-laden header portion, a product portion that includes the hermetic seal and a line of weakness. The information-laden header portion is removably connected to the product portion by the line of weakness. The hermetic seal is maintained after the information-laden header portion is removed from the product portion.
US12129096B2
An adapter (100) for connecting a refill container (200) with a container (300) during a refilling process. The adapter (100) has a first open end (10) and a second open end (11). The first open end (10) and the second open end (11) are connected to an, in particular, peripheral wall (12). A breaking element (20) is arranged inside the adapter (100). The breaking element (20) extends in the direction of the first open end (10) and is connected on one side via a web (21) to the wall (12).
US12129094B2
This present disclosure provides a vessel assembly for use in temperature sensitive shipping that can maintain a payload temperature across a range of temperatures. The vessel assembly of the present disclosure comprises a vessel having a single chamber, in which a plurality of PCMs are in contact, but immiscible, with each other. The present disclosure reduces the overall packaging materials used in a shipper box and prevents the “wrong” mixture of PCM-containing vessels from being used.
US12129090B2
A package or container contains a biodegradable resin and a microcapsule including therein a decomposition accelerator for the biodegradable resin. The microcapsule includes an outer shell containing a resin composition having photodegradability.
US12129079B2
A resealable airtight storage jar assembly that includes a portable jar body defining ajar opening, an inner cap member with an internal sidewall extending from an upper wall and an inner cap sidewall extending from the upper wall and defining a threaded configuration corresponding to a threaded configuration defined on a sidewall of the portable jar body, wherein the inner cap member is operably configured to have a hermetically sealed position covering the jar opening. The jar assembly also includes an outer cap member with a lip radially extending from a sidewall thereon and to restrict longitudinal movement of the inner cap member thereover. The jar assembly also includes an elastomeric gasket coupled to the inner cap member and operably configured to seat over and seal the jar body defining the jar opening.
US12129078B2
Systems and methods for coating one or more surfaces of a drinking container with diamond-like carbon. The systems and methods may position a metallic structure of a container into electrically-conducting contact with a first electrode, and use a probe that combines an electrode and gas channel to introduce a precursor gas into an internal compartment of a container for enhanced surface coating of the metallic structure.
US12129074B2
A food storage container stacking device includes a main body having a top surface and a bottom surface, a pair of ends and a pair of sides that define a perimeter of the top surface and the bottom surface. A lip extends from one end of the main body, the lip being oriented substantially perpendicular to the main body. The main body defines a central opening and a peripheral top support surface and a peripheral bottom support surface between the perimeter and the central opening.
US12129073B2
The present invention relates to an assembly composed of a container for a fluid and a dispenser packaging which makes it possible to receive said container and envelop it, at least partially, said container comprising a dispenser and at least one flexible wall, the container being suitable for dispensing said fluid by means of the dispenser by deforming said at least one flexible wall, the dispenser packaging being suitable so that at least part of said at least one flexible wall is accessible from outside of said dispenser packaging when the container is placed inside said dispenser packaging.
US12129071B2
A process for line production of plant growth medium pots or bags with a closed bottom end includes the steps of: i) continuously folding the free end of a continuous length of water and air permeable sheet material into a sheet material tube around and beyond a free end of a growth medium feeding tube; ii) forming a first sealing in the sheet material tube; iii) filling the sheet material tube with a measured amount of growth medium; iv) forming a second sealing in the sheet material tube; v) separating the part of the sheet material tube positioned downstream from the second sealing to form a first plant growth medium pot or bag with a closed end, repeating as needed to form a plurality of plant growth medium pots or bags.
US12129069B2
A system and a method for producing packages (100) provided with a reversible closing system (110) comprising a support (111) fixed to the package and a cap (112) reversibly applicable to the support are presented. The packages are formed by means of a forming tube (210), by forming a tubular structure of flexible material (300) wound around the forming tube. The reversible closing system is applied to the film of flexible material so that the support is fixed inside the packages. The application of the reversible closing system is performed when the film is wound around the forming tube.
US12129067B1
Separating devices for a blister tube include a blister tube feed device comprising a first transport means and an associated first transport means bearing, a blister discharging device arranged downstream of the blister tube feed device and comprising a second transport means and an associated second transport means bearing, a first drive coupled to the first transport means, and a second drive coupled to the second transport means, and a control device coupled to the first and second drives, the control device configured to temporarily exert a tensile force on the second portion of the blister tube in the transport direction with the aid of the second transport means, the tensile force being dimensioned in such a way that the second portion of the blister tube is separated from the first portion of the blister pouch at a separation aid. Methods and packaging devices using separating devices are also provided.
US12129066B2
There are provided systems and methods relating to assembling unpacked merchandise in containers. In one form, the system includes an order of merchandise items to be assembled in containers, and a predetermined set of containers defining different sizes and including at least two different types of containers. The system also includes a control circuit configured to: receive notification of the order, select a first type of container, determine a first subset of the plurality of merchandise items to be received in the selected type of container, select a size of the selected type of container to receive the first subset of merchandise items, and instruct the disposition of the first subset of merchandise items within the selected type and size of container.
US12129064B2
A hanger can include an elongated body defining: a first end defining at least one aperture; and a second end, the first end and the second end defined at opposite ends of the hanger along a longitudinal direction, the hanger being configured to support a hanging object at the second end; and a UV indicator.
US12129061B2
A lid for a vacuum sealing device may include a housing that supports a sealing station. The housing may define a sealing surface with a sealing perimeter that is able to seal against a canister body when the sealing surface is located on the canister body so that the sealing surface and the canister body together define a sealed volume. The sealing station is supported by the housing and extends from the housing. The sealing station is configured to heat seal an open bag, the sealing station being located within the sealing perimeter of the sealing surface such that when the lid is located onto the canister body, the sealing station is disposed within the sealed volume. The lid may have an internal pump for vacuum sealing operations or may receive a vacuum from an external source.
US12129056B2
A release system for the release of satellites from a launch vehicle is provided that includes: (i) a torsion bar, having a first end which is fixed by means of support means to a launch vehicle and is locked in rotation around a longitudinal axis of the torsion bar, and a second end which is connected by means of hinge means to the launch vehicle and is free to rotate around the longitudinal axis; (ii) at least one launch arm extending perpendicularly from the torsion bar and comprising (a) a torsion lever having a first end which is fixed to the torsion bar in an integral manner, and (b) a guide having a first end connected to a second end of the torsion lever, and a second free end; (iii) at least one slider which is fixed in an integral manner to a satellite to be launched and arranged to engage the guide in a sliding manner; and (iv) and a limit stop element designed to act upon the torsion lever to stop the rotation of the launch arm around the longitudinal axis.
US12129049B2
An electric pushback vehicle includes a frame having a forward portion and a rear portion. The vehicle further includes front drive axle and a rear drive axle configured to communicate power to ground engaging members. A traction battery is housed within the electric pushback vehicle and provides electric power to an electric motor to drive an output shaft. A transmission is connected to receive mechanical power from the electric motor through a torque converter.
US12129045B2
A sparging evaporator for an inerting system including an outer vessel, an inner vessel within the outer vessel, and a plenum formed between the inner and outer vessels. The outer vessel includes a gas inlet for receiving inlet gas into the plenum, and a liquid inlet for receiving liquid fuel into the plenum. The inlet gas in the plenum generates a gas pressure that is exerted against a free surface of the liquid fuel in the plenum thereby forcing the liquid fuel and the inlet gas through an inlet of the inner vessel. The inner vessel contains a structure that promotes liberation of fuel vapor from the liquid fuel and enables the inlet gas in the liquid fuel to sparge the fuel vapor in the liquid fuel, thereby forming a fuel-enriched gas mixture that can be fed to a reactor of the inerting system.
US12129044B2
A cooling architecture for an integrated hydrogen-electric engine having a radiator and a hydrogen fuel cell includes a t and a manifold. The turbine is disposed in fluid communication with the hydrogen fuel cell. The turbine is configured to compress a predetermined amount of air and direct a first portion of the predetermined amount of the compressed air to the fuel cell for generating electricity that powers the integrated hydrogen-electric engine. The manifold is disposed in fluid communication with the turbine and positioned to direct a second portion of the predetermined amount of compressed air to the radiator for removing heat from the radiator.
US12129042B2
An acoustic assembly including a multicellular acoustic panel having at least one through cavity along a direction X, wherein the acoustic assembly further includes at least one sealing element including a body enclosing one or more acoustic cells, the body being able to be inserted into the cavity and extending along the direction X between a first face and a second face, the sealing element further including a seal on the second face of the body able to ensure the sealing with the acoustic panel.
US12129035B2
The invention relates to an electrical air conditioning system for air conditioning a cabin (10) of an aircraft comprising a source (11) of fresh air, a dynamic air circulation duct (12), a motorized compressor (13) comprising an air inlet connected to said source of fresh air, and an air outlet connected to a primary cooling exchanger (PHx) housed in said dynamic air duct; an air cycle turbomachine (14) comprising at least a first compressor (15) and a first turbine (17) that are mechanically coupled to one another, said first compressor comprising an air inlet that can be connected either to said primary cooling exchanger (PHx) or to said source (11) of fresh air, and an air outlet connected to a main cooling exchanger (MHx) housed in said dynamic air duct, said first turbine (17) comprising an air inlet that can be connected either to a discharge port (54) for discharging stale air from said cabin or to said main cooling exchanger (MHx), and an air outlet that can be connected either to said cabin (10) or to an air injector (52) opening into said dynamic air duct.
US12129028B2
In a method of expanding a flight envelope of an aircraft comprising a pair of wing halves and extendable leading-edge flaps at leading wing edges of the wing halves towards higher transonic flight Mach numbers, at least one of the leading-edge flaps at one of the two wing halves is extended in flight direction, when approaching the flight envelope with increasing flight Mach number of the aircraft.
US12129021B2
A tail-rotor vibration dampener system for an aircraft is provided. The system includes a fuselage and an open rotor assembly including a powerplant and a set of rotor blades. The system further includes at least one actuator unit connecting the open rotor assembly to the fuselage. The actuator unit includes a hydraulic actuator controlling a position of the open rotor assembly in relation to the fuselage and a dampening device operable to cancel a vibration emanating from the open rotor assembly. The system further includes a computerized vibration dampening controller, including programming to determine a frequency of the vibration emanating from the open rotor assembly and control the dampening device to cancel the vibration emanating from the open rotor assembly based upon the frequency.
US12129019B2
An aircraft and flow guide system including a flow guide structure are provided. The aircraft has an airflow generator, and a duct extending from the airflow generator to an outlet through which an airflow generated by the airflow generator is expelled. The flow guide structure is positioned towards the outlet, and has a set of flow guide surfaces defining a plurality of channels. At least some of the flow guide surfaces divert at least some of the airflow from a first direction in which the airflow travels immediately upstream of the flow guide structure towards a second direction that is orthogonal to the first direction. The flow guide structure is reorientable to cause the at least some of the flow guide surfaces to divert at least some of the airflow towards a third direction that is orthogonal to the first direction.
US12129012B2
Resilient elongated tubular seals that are flexible and that comprise selected geometric cross-sections and that can absorb compressive forces to seal gaps between adjacently positioned aircraft cabin structure and that can further expand outwardly as compressive forces change or abate and methods of installation of such tubular seals are disclosed.
US12129009B2
A Flettner rotor that employs localized suction over its surface improves performance and fuel efficiency. Simulations and analysis show that such a method can significantly improve the performance of the Flettner rotor. Improvements in rotor performance enable reduction in fuel costs and greenhouse gas emission by ships or other modes of transport. Improvements in rotor performance can also reduce noise for applications such as drones or other devices having rotors.
US12129003B2
A boat having a transom and a rear platform extending at least partially across the transom. The rear platform includes a hatch defining at least partially the rear platform, the hatch having a bottom surface, and a hatch pivot for pivoting the hatch about a hatch pivot axis from a first hatch position to a second hatch position. The boat is free of an enclosed engine compartment. The hatch at least partially defines thereunder a space for receiving a marine outboard engine. The space extends rearwardly of the transom and is open at a rear of the boat.
US12129002B1
A system for joining modules having capillaries integrated in the module walls that may be fluidly coupled to the interior volume of modules comprising modular elements and attachable components, including a male end adapted to join a single-piece female end by rotating the male end into the single-piece female end such that data bus terminals align and power bus terminals align. The system can be assembled from these modular elements and components to meet desired mission and performance characteristics without the need to purchase specially designed systems for each mission. The joints connecting the modules are designed such that power and data connections between modules are reliably made.
US12128999B1
A system for joining ferry modules comprising modular elements and attachable components, including a male end adapted to join a single-piece female end by rotating the male end into the single-piece female end such that data bus terminals align and power bus terminals align. The system can be assembled from these modular elements and components to meet desired mission and performance characteristics without the need to purchase specially designed systems for each mission. The joints connecting the modules are designed such that power and data connections between modules are reliably made.
US12128980B2
The present disclosure describes various aspects of crank-based lighting, which may improve visibility of pedal-based vehicles or conveyances. In some aspects, a light generating apparatus includes a crank interface and lighting system. The crank interface may facilitate mounting of the apparatus to a crank (or crankarm) of a bicycle or other pedal-based vehicle. The lighting system may generate or emit light based on information indicating an angle, movement, and/or position of the crank, such as to cause light emission to emulate or project leg movement of a rider.
US12128977B2
A vehicle includes a chassis and a front axle assembly. The chassis includes a first frame rail defining a first vertical plane and a second frame rail defining a second vertical plane. The front axle assembly includes an axle and a steering assembly. The axle is coupled to a front end of the first frame rail and the second frame rail. The steering assembly includes a pair of wheel hubs coupled to opposing ends of the axle, a steering gear mechanism including a first gear box and a second gear box, and a linkage assembly coupling the steering gear mechanism to the pair of wheel hubs to facilitate steering the pair of wheel hubs through actuation of the steering gear mechanism. The first gear box and the second gear box are positioned between the first vertical plane and the second vertical plane.
US12128969B2
An electric power source device includes an auxiliary electric power source for a main electric power source that supplies electric power to electric power supply targets, including an electric circuit of a control system for controlling a specific control target and an electric circuit of a power system that requires larger electric power than the electric circuit of the control system; and a selection circuit configured to supply the electric power from one electric power source having a higher voltage, out of the main electric power source and the auxiliary electric power source, to at least the electric circuit of the control system among the electric power supply targets.
US12128967B2
To provide a control apparatus for AC rotary machine and an electric power steering apparatus which can reduce the error component of the current detection value close to the mechanical resonance period of AC rotary machine. A control apparatus for AC rotary machine detects currents which flow into three-phase windings at a current detection period which is a first natural number times of a carrier period; calculates current detection values, by performing a current addition processing which adds current detection values detected at this time, and current detection values detected before an addition period which is a second natural number times of the current detection period; and calculates the voltage command values of three-phase based on the current detection values after current addition processing, wherein the second natural number is set to a natural number that the addition period becomes the closest to the half period of the mechanical resonance period.
US12128953B2
A cowl cross bar assembly with a reduced weight and an increased stiffness. The cowl cross bar assembly includes a first pipe and a second pipe that are hollow and disposed laterally inside a chassis, a dash mounting member disposed between both ends of the first pipe, and a stiffener accommodated in an internal space of the dash mounting member and configured to absorb collision energy generated in a collision of a vehicle.
US12128952B2
Disclosed is a device for attaching, to a motor vehicle chassis, the rear end of the side rails of an engine cradle receiving an electric drive propulsion system for the vehicle. According to the device of the invention and for each of the side rails (3a, 3b), the attachment device comprises a junction interface (5a, 5b) that includes at least a first junction member (7a, 7b). The first junction member (7a, 7b) is, on one hand, attached longitudinally (L1) to the rear end (4) of the side rail (3a, 3b) via a front end (8a) of the first junction member (7a, 7b) and, on the other hand, attached transversely (T1) to a lateral side member (1a, 1b) constituting the chassis (1) via a rear end (8b) of the first junction member (7a).
US12128946B2
A steering device includes: an upper column having a cylindrical shape that is disposed on a radially outer side of a steering shaft; a lower column having a cylindrical shape that is fitted to the upper column and is capable of relatively moving in an axial direction with respect to the upper column; an attachment portion that is attached to the upper column and provided with a column long hole; a column bracket that includes a side plate portion located on a side of the upper column and is attached to a vehicle body; a liner slot that is inserted into the column long hole of the attachment portion and restricts an axial movement; and a pin that extends along a vehicle width direction and penetrates through the side plate portion and the liner slot, in which the liner slot is provided with a through-hole through which the pin penetrates.
US12128937B2
The disclosure relates to a valve assembly and a method for controlling the air suspension level of a rail vehicle. A system is provided, which is constructionally simple to build and easy to parameterise, for controlling the air suspension level of a rail vehicle. The object of the disclosure is achieved by a valve assembly for controlling the air suspension level of a rail vehicle, comprising a proportional directional valve, a sensor means for continuously detecting a distance variable representing the distance of a carriage body from a chassis or bogie of the rail vehicle, and a digital control device, wherein the control device is designed to be programmable for determining a control deviation based on the actual distance detected by the sensor means and a comparison with a predefinable target distance, and for continuously generating control variables as a linear function of the determined control deviation and the carriage body travelling speed. The object is also achieved by a method for controlling the air suspension level of a rail vehicle with a proportional directional valve, a sensor means for continuously detecting a distance variable representing the distance of the carriage body from a chassis or bogie, and a digital control device, wherein a control deviation is determined by the control device based on a comparison of the actual distances detected by the sensor means with a predefinable target distance, and a control variable is generated continuously as a linear function of the determined control deviation and the carriage body travelling speed.
US12128935B2
A bolster beam is correspondingly connected to a connection base by means of a damping unit; the radial dimensions of an outer wall of an inner supporting member and an inner wall of an outer supporting member gradually decrease from one end to the other end in a vertical direction; one of the inner supporting member and the outer supporting member is connected to the connection base, and the other one is connected to the bolster beam; when in use, the inner supporting member and the outer supporting member tend to be close to each other, and since surfaces, close to each other, of the two are configured to be tapered, the two can-not be relatively separated; when getting closer to each other, the inner supporting member and the outer supporting member produce a compression action on an intermediate buffer member, and the intermediate buffer member is elastically deformable.
US12128929B2
Methods and systems for controlling navigation of a vehicle are disclosed. The system will first identify a plurality of goal points corresponding to a drivable area that a vehicle is traversing or will traverse, where the plurality of goal points are potential targets that an uncertain road user (URU) within the drivable area can use to exit the drivable area. The system will then receive perception information relating to the URU within the drivable area, and identify a target exit point from the plurality goal points based on a score. The score is computed based on the received perception information and a loss function. The system will generate a trajectory of the URU from a current position of the URU to the target exit point, and control navigation of the vehicle to avoid collision with the URU.
US12128927B2
A method for situation aware processing, the method may include detecting a situation, based on first sensed information at a first period; selecting, from reference information, a situation related subset of the reference information, wherein the situation related subset of the reference information is related to the situation; and performing, by a situation related processing unit, a situation related processing, wherein the situation related processing is based on the situation related subset of the reference information and on second sensed information sensed at a second period, wherein the situation related processing comprises at least one out of object detection and object behavior estimation.
US12128918B2
An in-vehicle sensor cleaning system installed in a vehicle includes: a cleaning unit configured to automatically or manually perform cleaning of an in-vehicle sensor installed in the vehicle; a setting unit configured to set an automatic cleaning function to on and off, the automatic cleaning function causing the cleaning unit to automatically perform the cleaning of the in-vehicle sensor; and a notification unit configured to provide a notification about switching a setting of the automatic cleaning function, based on information on past cleaning of the in-vehicle sensor, when the automatic cleaning function is set to off by the setting unit.
US12128916B2
A detection device 1 is provided with: a detection unit 121 which detects an object present around a vehicle V; a specification unit 122 which specifies a detection continuation time period in which the detection unit 121 has continuously detected the object; and an information output unit 123 which, on the condition that the detection continuation time period specified by the specification unit 122 has exceeded a determination time period for determining whether or not the object is a detection target object, outputs presence information indicating detection of the target object by the detection unit 121.
US12128915B2
A device for providing image data of an image to be output on a display apparatus in a motor vehicle. The device having an integrated circuit, which includes a computing unit as a component in a first circuit section and a superimposition unit as a component in a second circuit section. The computing unit determines first partial image data relating exclusively to a portion of the image that is safety-relevant. The superimposition unit superimposes second partial image data that are not safety-relevant onto the first partial image data in such a way that the image data in the entire portion of the image, or in regions of the portion for which the first partial image data are not transparent, are predefined by the first partial image data.
US12128906B2
Technologies assessing driver behavior include a vehicle telematics device configured to analyze sensor data from one or more vehicle sensors to detect whether a vehicle event has occurred and to communicate with a vehicle camera system to obtain video data associated with the detected vehicle event. The vehicle telematics device may transmit the obtained sensor data and/or video data to a remote server system. The vehicle telematics device may also receive a notification from the vehicle camera system that indicates the vehicle camera system has detected a vehicle event. In response to the notification, the vehicle telematics device may obtain sensor data form the one or more vehicle sensors and/or video data from the vehicle camera system and transmit the sensor and/or video data to the remove server system.
US12128904B2
The invention concerns a method and a system for recognizing the presence of any irregularities of any road pavement.
US12128895B2
An autonomous driving device includes an execution network configured to determine a target speed of a driving vehicle according to state information history including a plurality of state information for road environment. The plurality of state information are generated at a plurality of times. The execution network includes a spatial attention network configured to receive the state information history and to generate feature data reflecting spatial importance based on the state information history; and a temporal attention network configured to determine the target speed of the driving vehicle by applying temporal importance to an output of the spatial attention network.
US12128882B2
A vehicle 1 as a host vehicle includes: detection unit that detects a translationally-moving two-wheeled vehicle 9 traveling in front of or alongside the host vehicle; an on-board communication device capable of communicating with a communication device mounted on the vehicle 9; an ECU that determines whether the host vehicle is at either one of blind spots BR and BL of the vehicle 9, based on a detection result of the detection unit, and that transmits a warning notification from the on-board communication device to the communication device mounted on the vehicle 9 when determining that the host vehicle is at the blind spot BR or BL. In this case, it is preferable that the ECU changes an actuation condition so that an automatic operation according to contact avoidance control is started more promptly than when the host vehicle is determined to be outside the blind spots BR, BL.
US12128878B1
Techniques for controlling a vehicle to select parking spaces are discussed herein. The vehicle may receive a request to travel to a destination and obtain information about a first set and a second set of parking spaces within a threshold distance of the destination. The vehicle may determine a first likelihood of availability associated with the first set of parking spaces and a second likelihood of availability associated with the second set of parking spaces. The vehicle may determine a first cost associated with a first route to the first set of parking spaces and a second cost associated with a second route to the second set of parking spaces by the cost function. Upon determining that the first cost is equal to or less than the second cost, the vehicle may navigate based on the first route and park within one of the first set of parking spaces.
US12128877B2
Signals usable to determine a path of a vehicle towards a particular stopping point in a vicinity of a destination are detected from an individual authorized to provide guidance with respect to movements of the vehicle. Based at least in part on the signals and a data set pertaining to the external environment of the vehicle, one or more vehicular movements to be implemented to proceed along the path are identified. A directive is transmitted to a motion control subsystem of the vehicle to initiate one of the vehicular movements.
US12128864B2
A system and method of checking sealing of a brake caliper housing. The method may include determining a level of moisture in a cavity of a brake caliper housing with a sensor. In another configuration, the method may determine whether a detected pressure inside the cavity remains stable for a predetermined period of time.
US12128857B2
An example operation includes one or more of detecting, by a component in a transport, that another component has been removed, detecting, by the component, that a replacement component has been added in the transport, providing, by the component, data to the replacement component, wherein the data attempts to subvert an authorized functionality of the replacement component, and responsive to a non-subversion of the authorized functionality, permitting, by the component, use of the authorized functionality of the replacement component.
US12128856B2
The present invention relates to a device for cleaning the interior of the vehicle chassis rail. The chassis cleaning device having a body with a first end spaced apart from a second end with a longitudinal central axis extending through the body. An inlet connector extends from the first end of the body with the inlet connector adapted to connect to a liquid source. An elongate outlet extends from the second end of the body with the elongate outlet fluidly connected to the inlet connector. At least one discharge outlet is aligned adjacent to an end of the elongate outlet and a plurality of magnets are mounted within the second end of the body and equidistantly positioned around the longitudinal central axis. In use, the elongate outlet is inserted through an aperture in a wall of the chassis rail, the plurality of magnets are adapted to releasably couple the body of the chassis cleaner to the chassis rail and when the liquid source is connected to the inlet connector the liquid is expelled through the at least one discharge outlet to clean the interior of the chassis rail.
US12128854B2
A cleaning device for a vehicle, with which at least one cleaning location is cleaned with pressurized cleaning liquid and/or pressurized ambient air, is proposed, including: a pump-compressor stage for sucking up and conveying the cleaning liquid and/or the ambient air, a fluid path which fluidically connects the pump-compressor stage upstream to a cleaning liquid tank and to an environment of the cleaning device, and a fluid distribution apparatus downstream of the pump-compressor stage, which is fed with the cleaning liquid and/or the ambient air by the pump-compressor stage, the fluid distribution apparatus being fluidically connected to the cleaning location. A vehicle with such a cleaning device, the first and the second use, and a cleaning method for a vehicle are also proposed.
US12128851B2
A motor vehicle (1) has a driver's seat (8) which is assigned a safety belt (20) for a driver. The safety belt (20) here is held on a pivotable bracket (13). This bracket (13) is pivotable between a releasing position, which permits entry, and a restraining position, which protects the driver. The bracket (13) here is disposed in such a manner that said bracket (13) in the releasing position holds the safety belt (20) in a position in which the latter impedes the driver. In order to avoid any impediment of the driver in the restraining position of the bracket (13), the bracket (13) above the driver's seat is elbowed away from the latter.
US12128844B2
The present disclosure provides an occupant protection system protecting an occupant in a vehicle by a protection device provided in the vehicle the occupant protection system having a gas generator, a prediction unit, and a control unit.
US12128842B2
Systems and methods are provided for improving safety of one or more vehicle occupants. An example method for improving safety of one or more vehicle occupants includes accessing interior vehicle configuration data that is generated by, or derived from data generated by an interior data collection component, the data representing an interior space of a vehicle; determining, by processing the interior vehicle configuration data, location and orientation of one or more vehicle occupants; selecting a plurality of vehicle safety components to be active based on the location and orientation of the one or more vehicle occupants, and setting the plurality of vehicle safety components to an active state in which the plurality of vehicle safety components are deployed, when an emergency condition is detected.
US12128832B2
The radome for vehicles comprises a radio transmissive transparent layer (9) and a decorative element (6), wherein the decorative element (6) comprises a brightness and tone element (62) comprising a metal layer (621) and one or more metalloid layers (622). The brightness and tone element (62) preferably comprises two metalloid layers (622, 623), each metalloid layer being made from a different metalloid. It permits to provide a radome for vehicles that allows to match a wider range of appearance specifications (brightness and color tone) defined by the car manufacturers.
US12128824B2
An automatic control apparatus and a method of in-vehicle infotainment volume are proposed. The automatic control apparatus is configured to detect obstacle (people or object) around a vehicle using a parking assistance system sensor, and to adjust the playback volume of an in-vehicle infotainment (IVI) to be automatically reduced when an obstacle is detected around the vehicle, and to automatically adjust the playback volume of the IVI during not only reversing but also forward moving of the vehicle.
US12128816B2
A safety zone system that includes a vehicle and at least one safety cantilevered arm that is operably engaged with the vehicle. The vehicle include a front end, a rear end opposite to the front end, a longitudinal direction that extends from the rear end to the front end, and one or more pairs of wheel assemblies engaged at least at the rear end. The at least one safety cantilevered arm is also moveable between a stored position and an operating position and is a single unit. The movement of the at least one safety cantilevered arm is also performed entirely along an arm axis that is perpendicular to the longitudinal direction of the vehicle. In the operating position, the at least one safety cantilevered arm is positioned at the bottom end of the vehicle and positioned above the one or more pairs of wheel assemblies of the vehicle.
US12128805B2
A vehicle system includes a seat of a vehicle, and a vibration generation device provided in the seat. The vibration generation device includes a housing, a diaphragm supported on the housing, an actuator attached to at least one of the housing and the diaphragm, and a sensor, including a detection electrode, and configured to detect a user approaching the detection electrode. The diaphragm and the detection electrode are famed by a common member.
US12128803B2
The present disclosure relates to an armrest tilting device provided on a seat and capable of tilting and adjusting an armrest capable of supporting a user's arm. The armrest tilting device includes: a shaft which is installed on a seat and has one end installed on an armrest in such a way as to be relatively rotated; a housing which is fastened to the armrest and supports the shaft in the state where the shaft is installed on the armrest; a bracket which is fastened and fixed to the shaft; a ratchet which is rotatably fastened to a hinge member fastened to the bracket; a sector gear portion which is fastened to and rotates together with the armrest and is engaged with the ratchet; a guide plate which is provided on the sector gear portion and where the ratchet moves in one area while being separated from the sector gear portion; and an elastic member which applies an elastic force such that ratchet gear teeth formed on the ratchet are meshed with sector gear teeth formed on the sector gear portion.
US12128802B2
Disclosed are a vehicle seat cover made of an artificial suede. The vehicle seat cover includes a top layer provided in the top portion, a bottom layer provided in the bottom portion, and a intermediate layer positioned between the top layer and the bottom layer. Each of the layers has a tricot texture, and the top layer includes the first yarn having a configuration in which the dope dyed microfiber yarn and the first high shrinkage yarn are interlaced. Thus, the suede material may have superior friction fastness and the light fastness and the vehicle seat cover is manufactured at less cost than a vehicle seat cover made of a conventional artificial suede.
US12128798B2
Disclosed is a seat for a vehicle configured to variously adjust a seat position between, for example, a full-flat mode, a relaxation mode, a cushion tip-up mode, a full-bed mode, a walk-in mode, and a rear-view mode using a first hinge shaft to rotate the entire seat, including a seatback and a seat cushion, and a second hinge shaft to rotate the seatback.
US12128792B2
A system for predicting degradation of a battery for use in an electric vehicle is presented. The system includes a computing device communicatively connected to at least a pack monitor unit, wherein the at least a pack monitor unit is configured to detect a battery pack datum of a plurality of battery modules incorporated in a battery pack. The computing device is further configured to receive the battery pack datum as a function of the at least a pack monitor unit, generate, as a function of the battery pack datum, a battery pack model associated with the battery pack of the electric vehicle, and determine a battery degradation prediction as a function of the battery pack datum and the battery pack model.
US12128787B2
A battery use system includes a battery removably mounted on an electric power device, a charging device configured to charge the battery, and a server configured to communicate with the charging device. The charging device is configured to transmit the identification information of the battery accommodated in the accommodation unit to the server via a first communicator and control charging of the battery and/or detachment of the battery on the basis of reception information received by the first communicator from the server. The server is configured to determine whether or not the charging of the battery and/or the detachment of the battery accommodated in the accommodation unit are available on the basis of the identification information received by a second communicator from the charging device and provision information provided from an information provider and transmit transmission information on an availability determination result to the charging device via the second communicator.
US12128786B2
A system for checking metering accuracy of an EVSE unit includes an EVSE unit including a cable and a charge handle. The system includes an electric vehicle including a charging port configured to be coupled to the charge handle. The electric vehicle is configured to be charged by the EVSE unit using the cable and the charge handle. In place of the electric vehicle, an electric vehicle-emulating electric load can be used. The system includes an inline electric meter device having a terminal end and a distal end. The charging port of the electric vehicle is configured to be coupled to the terminal end of the inline electric meter device. The charge handle is configured to be coupled to the distal end of the inline electric meter device. The inline electric meter device may be connected in various configurations. The inline electric meter device includes a display, a microprocessor, test and diagnostic logic, a report generator, a camera, and/or a GPS receiver.
US12128766B2
An in-vehicle display device according to the present disclosure includes a front plate and a housing. In the front plate, a first arc surface bulging outward is formed on a front surface side in an outer peripheral edge portion. The housing supports the front plate from a rear surface side. In the housing, a second arc surface bulging outward is formed on a side surface side, and a part on the side surface side protrudes toward the front surface side from a rear surface of the front plate, and faces the outer peripheral edge portion of the front plate.
US12128765B2
An embodiment vehicle includes an audio video navigation (AVN) device configured to execute an application, a display configured to display a screen of the application, an input device configured to receive a command from a user, and a processor configured to receive a backup command through the input device, in response to the backup command, generate snapshot data of the application being executed, extract a keyword based on the screen displayed on the display, generate metadata corresponding to the snapshot data and including a keyword, receive a restoration command that includes the keyword, the restoration command received thorough the input device, based on the received restoration command, select the metadata including the keyword, and restore data of the application based on the snapshot data corresponding to the selected metadata.
US12128761B2
A work vehicle is provided with a support member that supports an output shaft of a wheel differential mechanism between a differential case and a planetary reduction mechanism. The support member is configured to engage the output shaft relatively immovably in a direction along the axis of the output shaft.
US12128757B2
In a lid assembly structure 1 which includes a base member 2, a lid 3, and an opening/closing mechanism 5 and in which the opening/closing mechanism 5 includes a biasing member 8, during assembling of the base member 2 and the opening/closing mechanism 5, the biasing member 8 is guided by a guide portion 90 which is a part of the opening/closing mechanism 5, and a state of the biasing member 8 is changed from a temporary assembled state where a second engagement end 82 of the biasing member 8 and a temporary engagement portion 93 engage with each other to a main assembled state where the second engagement end 82 and a main engagement portion 91 of a mating member engage with each other, thereby accumulating at least a part of a biasing force in the biasing member 8.
US12128755B2
A coolant system includes a first and a second coolant tank, the first and second coolant tanks are connectable to each other by means of a coolant supply conduit and a first coolant feeding conduit, wherein the first coolant feeding conduit comprises a fluid pump. The coolant system hereby provides an active coolant pressure control with service filling ability.
US12128749B2
The present disclosure relates to an energy store housing assembly for a motor vehicle. The energy store housing assembly includes an energy store housing and an underride guard coupled to a bottom side of the energy store housing. The underride guard includes a sandwich arrangement, which includes an upper cover plate disposed on the top side of the sandwich arrangement facing the energy store housing, a lower cover plate disposed on the bottom side of the sandwich arrangement, and a filling material disposed between the upper cover plate and the lower cover plate. The underride guard includes a plurality of ribs extending along the top side of the sandwich arrangement.
US12128746B2
In accordance with embodiments of the invention, an automobile cover is provided. The automobile cover includes an inner cover operable to envelope a vehicle and an outer cover attached to the inner cover. The outer cover is operable to cover the inner cover in a covered position. The outer cover includes a first opposing flap and a second opposing operable to overlap in the covered position and operable to be pulled from the covered position into an uncovered position. One or more straps are attached to the first opposing flap and operable to pull the first opposing flap from the covered position to the uncovered position. One or more straps are attached to the second opposing flap, said one or more straps operable to pull the second opposing flap from the covered position to the uncovered position.
US12128743B2
A resin window panel provided in a vehicle including a vehicle body that has a peripheral edge surrounding a window frame, the resin window panel that is attached to the peripheral edge with an adhesive containing a plasticizer, the resin window panel includes: a first resin panel part whose top surface has a hard coating layer, the first resin panel part made of polycarbonate; and a second resin panel part stacked on a backside surface of the first resin panel part, the second resin panel part made of polyethylene terephthalate.
US12128738B2
A cabin air extraction assembly for a vehicle that utilizes an air extractor input port disposed in the rear portion of the cabin of a vehicle that conduits cabin air to a snorkel assembly disposed within a sealed or substantially sealed body panel or side structure near the rear wheel well of the vehicle, for example. This snorkel assembly includes a one-way pressure relief valve. Because the snorkel assembly is positioned such that it is not prone to obstruction or the intake of water in a wading application, there is no risk of water intrusion into the cabin of the vehicle, even if the bottom portion of the snorkel assembly is disposed below the wading line during vehicle operation. Thus, the cabin air extraction assembly and associated method promote passenger comfort by allowing the HVAC system of a vehicle to be operated using fresh, outside air without cabin pressure problems, even during a wading application.
US12128737B2
A headliner trim for a motor vehicle includes a main body, at least one air channel formed in the main body for conducting an air flow through the main body, and at least one air outlet opening formed in the main body, through which air outlet opening the air flow conducted in the air channel can flow into the interior of the motor vehicle. The main body is formed from a particle foam, such as expanded polypropylene (EPP) or expanded polyethylene (EPE).
US12128726B2
Systems, computer-implemented methods, and computer program products relating to jerk of a vehicle damper are provided. According to an embodiment, a system can comprise a memory that stores computer executable components and a processor that executes the computer executable components stored in the memory. The computer executable components can comprise a control signal determination component that determines movement of a front damper of a vehicle, an amount of time between a first time when the movement of the front damper occurs and a second time when a rear damper of the vehicle will experience a condition which caused the movement of the front damper, and a front damping coefficient of the front damper, and determines a rear damping coefficient of the rear damper configured to mitigate rear suspension impact with an end stop caused by rear suspension compression or rebound based on the movement of the front damper, the amount of time, and the front damping coefficient, and a damper adjustment component that adjusts the rear damper to the rear damping coefficient.
US12128722B1
A gravity-assist energy harvesting system incorporates a gravitational positive displacement pump. The gravitational positive displacement pump has a cylinder and a reciprocating piston inside the cylinder. The piston is adapted for movement along a compression stroke and an opposite extension stroke in response to a gravitational bounce. A fluid drive assembly is operatively connected to the gravitational positive displacement pump and a fluid source, such that operational movement of the gravitational positive displacement pump circulates the fluid thereby actuating the fluid drive assembly. A generator is operatively connected to the fluid drive assembly and is adapted for generating electrical energy upon actuation of the fluid drive assembly.
US12128719B2
A hitch assembly adapted for securement in a tube receiver connected to a towing vehicle below its bumper includes a hitch base with a recessed profile. The hitch base includes a shaft sized for reception in the tube receiver and a draw bar connected to the shaft. The shaft is connected at a first end to an upper portion of the draw bar. The draw bar includes a plurality of pin receiving apertures extending laterally through a lower portion of the draw bar in vertical spaced alignment. The upper portion of the draw bar includes a recessed geometry or reduced profile relative to the lower portion of the draw bar.
US12128711B2
A pneumatic tire including a belt constituted by at least one belt layer on a tire radial-direction inner side of a tread portion. The belt layer includes a reinforcing element containing plural metal filaments aligned in a single row without being twisted together is embedded in an elastomer. The tread portion includes: two or more circumferential main grooves arranged within a width of a ground-contact surface; and land portions, and widthwise sipes are arranged in at least one of center land portion. The widthwise sipes each include: a linear portion linearly extending from the surface of the tread portion toward the tire radial-direction inner side; and a bent portion extending from the linear portion toward the tire radial-direction inner side, and the length of the linear portion increases from an extending length center portion of each widthwise sipe toward at least one of tread widthwise end portions.
US12128694B2
A recording apparatus includes: a housing; a recording section that performs a recording operation on a medium and is disposed inside the housing; a storage section that stores the medium; a transport route along which the medium is transported; a transport section that transports the medium; a reading section that reads an original sheet and is positioned higher than the recording section; a supply section that supplies the original sheet to the reading section; and a supply route through which the original sheet passes. Each of the supply and transport routes is formed at substantially right angles to a width of the housing. The transport route has a curved section in which the medium is turned over. The reading section is positioned behind the recording section in a depth direction from the front to rear surface of the housing.
US12128693B2
There is provided a tank including a liquid storage chamber and an outlet. The liquid storage chamber includes a base portion and a protruding portion, the base portion includes a first lateral wall and a second lateral wall which faces the first lateral wall in a left-right direction, the protruding portion protrudes from the second lateral wall in a direction away from the first lateral wall in the left-right direction, and the left-right direction is defined based on a usable posture in which the tank is disposed such that a lower surface of the liquid storage chamber is located below an upper surface of the liquid storage chamber. A distance between the outlet and the second lateral wall in the left-right direction is smaller than a distance between the outlet and the first lateral wall in the left-right direction.
US12128691B2
A recording apparatus includes a white ink jet head, a non-white ink jet head, and a control section that controls performing recording by performing a main scan a plurality of times in which, while a position of an ink jet head relative to the recording medium is moved, an ink composition is ejected from the ink jet head and is applied to the recording medium. The control section performs recording in a first recording mode in which the white ink composition and the non-white ink composition are applied to the same scan region of the recording medium by the same main scan and recording in a second recording mode in which the white ink composition and the non-white ink composition are applied to the same scan region of the recording medium by different main scans.
US12128688B2
A recording device is a recording device receiving liquid supplied from a liquid accommodation unit, and includes a recording unit configured to eject the liquid onto a transported medium, a support unit configured to support the medium at a position facing the recording unit, a first side frame and a second side frame that are configured to support one end side and the other end side of the support unit, a coupling frame configured to couple the first side frame and the second side frame, and a holding unit configured to hold the liquid accommodation unit. The coupling frame is located below the support unit, and the holding unit is located between the support unit and the coupling frame and between the first side frame and the second side frame.
US12128681B2
A temperature sensor detects temperature of ink to be supplied to a plurality of nozzles. When, upon receiving a print request, a detection temperature detected by the temperature sensor is lower than a reference temperature, a control portion executes a preliminary vibration control to cause an ink meniscus oscillation to occur in each of the nozzles by vibrating the piezoelectric elements, and after the detection temperature increases up to the reference temperature, executes an ink ejection control to cause the ink to be ejected from the nozzles by vibrating the piezoelectric elements in correspondence with an output target image of a print request. When, upon receiving the print request, the detection temperature is higher than the reference temperature, the control portion executes the ink ejection control without executing the preliminary vibration control.
US12128680B2
A recording apparatus includes a recording head that has a plurality of nozzles that eject liquid onto a medium and a control section that controls an ejection of liquid by the recording head, wherein the control section controls the recording head to record a plurality of first patterns having mutually different densities on the medium in a intersecting direction that intersects a nozzle alignment direction in which the nozzles are arranged, and to record a plurality of second patterns for identifying positions of the nozzles in the nozzle alignment direction on the medium in the intersecting direction such that each of the plurality of first patterns is adjacent to the second patterns on at least one of one end side and the other end side in the intersecting direction.
US12128678B2
A recording device including a medium support portion configured to support a medium, a recording unit configured to perform recording on the medium, a movement unit configured to support the recording unit, and move relative to the medium support portion along a first axis, a first guide shaft provided on one side of the medium support portion, and extending along the first axis, and a second guide shaft provided on another side of the medium support portion, and extending along the first axis, and a driving unit configured to move the movement unit along the first axis.
US12128676B2
A printing apparatus includes: a printing section; a print conveyor conveying a medium in the printing section; a constant-speed conveyor conveying the medium at a variable constant conveying speed in a circulation route for duplex printing; a registration roller pair against which the medium to be conveyed to the printing section is caused to abut; and a processor determining a conveyance schedule for the medium based on at least one of a first conveyance route length between a downstream end portion in a conveying direction of the print conveyor and an upstream end portion in the conveying direction of the constant-speed conveyor and a second conveyance route length between a downstream end portion in the conveying direction of the constant-speed conveyor and the registration roller pair, and a medium length in the conveying direction of the medium.
US12128671B2
A printing apparatus 10 includes support member 12 that supports a core body Ra of a roll medium R, a transport mechanism 17 that transports the print medium S drawn out from the roll medium R, a first accommodation sidewall 27 and a second accommodation sidewall 28 arranged in a width direction, a print head 22, and a trailing edge detection section 60 that detects that all of the print medium S that is drawable out from the roll medium R has been drawn out by the transport mechanism 17, wherein the first accommodation sidewall 27 has groove 50, and the roll medium R is accommodated in an accommodation section 11 by engaging the support member 12 with the groove 50 and the trailing edge detection section 60 detects that the support member 12 is separated from an engagement surface 52 of the groove 50.
US12128662B1
An air bubble remover and an applicator for a tempered glass screen protector of an electronic device are provided. The air bubble remover includes a base and a rolling rod, where the base is provided with a mounting space for mounting an electronic device; the rolling rod is rotatably connected to the base and rotatable around a central axis of the rolling rod; and the rolling rod is automatically movable from one side of the mounting space across the mounting space to the other side of the mounting space, so as to remove a remaining air bubble between a tempered glass screen protector and the electronic device. When the rolling rod moves from one side of the mounting space across the mounting space to the other side of the mounting space, the rolling rod is abutted against the tempered glass screen protector to remove the remaining air bubble.
US12128657B2
A display device includes a display panel and a cushion layer disposed below the display panel. The cushion layer includes a first foam layer having a first density, a second foam layer disposed above the first foam layer and having a second density less than the first density, and a third foam layer disposed above the second foam layer and having a third density greater than the first density. The third form layer is disposed closer to the display panel than the first foam layer. The display device provides improved surface quality, impact resistance, and restoration properties.
US12128654B2
The present invention provides a low-gloss decorative sheet having an appropriately low level of wiping resistance, and thereby enables strongly adhering grime to be easily wiped off, thus being excellent in terms of easy cleanability. The present invention provides a decorative sheet comprising a base material sheet and at least a surface-protecting layer on the base material sheet, (1) the base material sheet being a thermoplastic resin sheet, (2) the surface-protecting layer having a surface free energy of 40 mJ/m2 or more, (3) an arithmetic average roughness (Ra0.08) measured on the surface side of the surface-protecting layer at a cutoff value of 0.08 mm with an evaluation length of 0.4 mm by a measurement method in accordance with JIS B0601:2001 being 0.60 μm or less, and (4) a specular glossiness on the surface-protecting layer side of the decorative sheet at an incident angle of 60° being 23 or less.
US12128648B2
A paper based overlay is provided. The overlay has a paper impregnated with a resin composition having an acrylic resin having a glass transition temperature in a range of from about −20° C. to about 40° C. and a resin content from about 15 to about 35 wt. % based on the weight of the overlay. The acrylic composition may include wax in the amount of about 0.005 to about 3.5 wt. % based on the weight of the resin composition. A method of producing the overlay is also provided. The overlay is highly water and abrasion resistant with low volatile content.
US12128639B2
A forming device includes: a forming jig extending along an axial direction; a forming die having a shape corresponding to a top part region and a wall part region of the forming jig; and a movement mechanism that moves the forming die so as to approach a bottom part region along a height direction HD. The forming die includes: a body part; a plate-shaped forming part that is attached to the body part so as to be swingable around a swing shaft; and a pressurization part that generates a pressurization force which causes a distal end part of the forming part to push a layered body against the wall part region when the forming die is moved by the movement mechanism so as to approach the bottom part region. In accordance with the distal end part, the part causes a contact surface to contact a region of the layered body.
US12128632B2
A 3D printing apparatus including a tank, a print platform, a motor, a force sensor, and a controller is provided. The tank is configured to accommodate a photocurable resin. The print platform is arranged adjacent to the tank. The motor is mechanically connected to the print platform. The motor is configured to drive the print platform to move. The force sensor includes a position encoder. The controller is electrically connected to the force sensor and the motor. The controller is configured to confirm whether the print platform is configured to reach a target position through a value of the position encoder.
US12128630B2
A method is disclosed for additively manufacturing a composite structure. The method may include receiving from a user a sketch of a cross-section of the composite structure and a desired height. The method may also include automatically generating a virtual model of the composite structure having a plurality of layers, each with a thickness related to the height. The method may further include receiving from the user at least one infill pattern for at least one of the plurality of layers, and causing an additive manufacturing machine to deposit a continuous fiber along segments of the at least one infill pattern.
US12128626B2
The invention relates to a method for producing three-dimensional, preferably porous, hydrogel structures by means of layer build-up technique, wherein the method comprises the following steps. Providing (S1) of a liquid hydrogel solution, preferably a liquid alginate solution, and a, preferably transportable, sample carrier. Layerwise applying (S2) the liquid hydrogel solution onto the sample carrier in a temperature environment, the temperature of which is below the freezing point of the hydrogel solution, to produce a frozen 3D layered hydrogel structure. In order to increase advantageously the porosity of the 3D layered hydrogel structure, i.e. the proportion of small voids, cavities and/or depressions in the 3D layered hydrogel structure, the method according to the invention further comprises the step of drying (S3) of the frozen 3D layered hydrogel structure, e.g. by means of freeze-drying, to produce a porous 3D hydrogel structure. The invention relates further also to a device for the layerwise building-up of three-dimensional hydrogel structures.
US12128620B2
A portable and ruggedized 3D printing system that is suitable for deployment in extreme environments for combat situations or disaster relief or in remote locations. The 3D printing system includes an enclosure that is openable, water resistant, and made of materials that are impact resistant. A 3D printer within the enclosure includes active and passive suspension systems that provide shock absorption. The 3D printing system further includes one or more internal and/or external sensors that monitor, in real time, various aspects of the printer, its environment, and/or the object being printed. Data from the one or more sensors is used to adjust internal print operating parameters via sensor fusion machine learning algorithms on an onboard processor.
US12128618B2
A three-dimensional printing support device includes: a variable table which includes an installation surface, and has a configuration configured to enable a shape of the installation surface to be freely modified; a drive unit for: (i) driving the variable table to change the shape of the installation surface; and a control unit for acquiring shape data relating to a shape of a printed article, which is a printing target; and (ii) controlling the drive unit based on the shape data such that the shape of the installation surface corresponds to the shape of the printed article.
US12128602B2
A method for manufacturing a part for an aircraft seat includes positioning a heating frame around a stacked structure, locally heating an edge of the stacked structure using a heating frame, externally heating the entire stacked structure, positioning the stacked structure inside a thermoforming mould provided with cutting punches, closing the thermoforming mould and applying a vacuum to the interior of the thermoforming mould, to simultaneously perform, during the same step of shaping the first cover and the second cover, a step of heat sealing an edge of the first cover to an edge of the second cover, bonding the first cover and the second cover to the foam core, and cutting the stacked structure along the circumference thereof using cutting punches.
US12128586B2
In a first aspect of the invention there is provided a method of manufacturing a wind turbine blade. The method comprises providing a mould for a shell of the wind turbine blade, the mould extending in a longitudinal direction from a root end to a tip end; providing a plurality of elongated root inserts; providing a root plate with a plurality of arcuately arranged connection points; at the connection points, connecting the root inserts to the root plate, such that the connected root inserts jointly form a contour of a portion of a root section of the wind turbine blade; and positioning the root plate relative to the mould in order to place the contour formed by the root inserts at least partially into the mould. The method further comprises providing a spacer having a decreasing thickness, and the connecting of the root inserts to the root plate comprises providing the spacer between the root inserts and the root plate.
US12128582B2
A method to provide a floor covering, including the steps of: providing a sheet vinyl; providing a PVC intermediate including at least a first layer of PVC material and at least a first reinforcing sheet, the first layer of PVC material providing the upper side of the PVC intermediate. The method also includes adhering the sheet vinyl to the PVC intermediate by laminating the lower side of the sheet vinyl to the upper side of the PVC intermediate.
US12128578B2
A winder unit for winding cutting line, for vehicle glazing panel removal, has a rotatable spindle shaft for winding the cutting line and a ratchet device mounted to the spindle shaft by means of a one-way rotational bearing or clutch. Typically the ratchet device has a component mounted to rotate in unison with the one-way rotational bearing or clutch. The improvement provides a rotational directional control providing 2 one-way rotational control devices in concert.
US12128575B2
A computer-implemented method of determining a location of a personal care device with respect to a skin surface of a subject, the personal care device being configured to perform a personal care treatment to the skin when in contact with the skin surface. The method includes receiving data representative of a measured degree of curvature of the skin surface within a first region of the skin surface of the subject, with which the personal care device is in contact; determining, by comparing the measured degree of curvature with curvature information for a plurality of regions of the skin surface of the subject contained in a database, an indication of a location of the first region of the skin surface on the subject; and performing, based on the determined indication of the location of the first region, an action in respect of the personal care device. A processing apparatus, a system, a personal care device, and a computer program product are also disclosed.
US12128572B2
Methods, apparatus, computing devices, computing entities, and/or the like associated with a robotic sortation system are provided. An example method may include receiving imaging data associated with a first item at a first sorting location of a material handling system, determining a sorting destination for the first item based at least in part on the imaging data, determining a plurality of first-tier robotic devices and a plurality of second-tier robotic devices based at least in part on the first sorting location and the sorting destination, and generating a first sortation scheme for the first item.
US12128567B2
Using machine learning to recognize variant objects is disclosed, including: identifying an object as a variant of an object type by inputting sensed data associated with the object into a modified machine learning model corresponding to the variant of the object type, wherein the modified machine learning model corresponding to the variant of the object type is generated using a machine learning model corresponding to the object type; and generating a control signal to provide to a sorting device that is configured to perform a sorting operation on the object, wherein the sorting operation on the object is determined based at least in part on the variant of the object type associated with the object.
US12128552B2
A collaborative robot line management system comprises a first bracket and a second bracket. The collaborative robot line management system is operable to manage the positioning and routing of a plurality of flexible lines relative to a collaborative robot. The first bracket comprises a support portion having a plurality of apertures formed therein, and a collaborative robot mounting portion configured to interface with a first mount of a collaborative robot. The second bracket comprises a support portion having a plurality of apertures formed therein, and a collaborative robot mounting portion configured to interface with a second mount of a collaborative robot. The collaborative robot mounting portions of the first and second brackets facilitate mounting of the first and second brackets to the collaborative robot at first and second mounting locations, respectively.
US12128545B2
A robot is for transferring a substrate. The robot includes an arm, a hand, and a tilter. The arm is movable. The hand is installed to the arm to project from it and holds and transfers the substrate. The tilter tilts an orientation of the hand. The hand includes a holder. The holder contacts the top surface and the bottom surface of the substrate. With the tilter, the holder holds the substrate keeping in contact with the top surface and the bottom surface of the substrate and applying forces to only one of two halves of the substrate bisected.
US12128544B2
An embodiment device for controlling a service robot includes a communication device configured to communicate with the service robot and a controller configured to detect a present situation of the service robot by using various pieces of sensor information acquired from the service robot, determine a task appropriate to the present situation of the service robot, wherein the task includes one or more behaviors, and control the service robot based on an action set for each of the one or more behaviors of the task.
US12128543B2
An information processing device is provided including a recognition unit that executes recognition processing used to determine an action of an autonomous operating body on the basis of sensor information collected, in which the recognition unit includes a feedback recognizer that recognizes feedback from a user on behavior executed by the autonomous operating body, and the feedback recognizer recognizes a degree of the feedback on the basis of recognition results of a contact action and a non-contact action by the user for the autonomous operating body.
US12128532B2
A universal joint includes a first joint member having a first end to which a second joint member is coupled and a second end to which a third joint member is coupled. The first and the second joint members are pivotally connected with each other about a first axis of rotation. The first and third joint member are pivotally connected with each other about a second axis of rotation. A retaining device which includes a first resilient member and a first retainer working cooperatively for preventing inadvertent relative movements between the first and the second joint members. The first retainer is urged by the first resilient member.
US12128526B2
The present disclosure provides abrasive articles that include an abrasive layer having a contact surface, a first layer coupled to the abrasive layer, and a second layer coupled to the first layer. The first layer is configured to provide contact pressure to the abrasive layer, such as through a higher hardness than the second layer. The second layer is configured to provide conformability to the abrasive layer, such as through a higher compressibility than the first layer. The resulting abrasive articles may exert a consistent contact pressure against a substrate with increased conformability around the substrate, reduced hysteresis, improved removal rate consistency, and/or improved lifetime over abrasive articles that do not use the multiple layer construction described above.
US12128510B2
An end assembly for use with a welding device having a chamber between the diffuser sleeve and the insert which allows for cooling the insert and for controlling the flow of gas through the end assembly. Some of the components of the end assembly such as the contact tip, insert and gooseneck are constructed of a conductive material which are securely held together in contact by a diffuser sleeve constructed of a dissimilar material. The end assembly provides better conductivity of the current through the end assembly for use of less energy during welding.
US12128507B2
A method for determining operating parameters to process a workpiece using a manufacturing processing system including a plasma arc gouging torch. The method includes positioning a plasma arc gouging torch at a location relative to a workpiece and determining a start point and an end point for each gouging path based on the location and a gouge profile. The method further includes using the gouging profile to determine first operating parameters for the plasma arc gouging torch for a first gouging path and determining second operating parameters for the plasma arc gouging torch for a second gouging path based on the gouge profile and the first gouging path. The second operating parameters include at least one of a second torch speed or a torch offset. The method also includes using at least one of the first or second operating parameters to process the workpiece with the plasma arc gouging torch.
US12128506B2
The invention relates generally to welding and, more specifically, to welding wires for arc welding, such as Gas Metal Arc Welding (GMAW) or Flux Core Arc Welding (FACW). In one embodiment, a tubular welding wire includes a sheath and a core, and the core comprises a rare earth silicide component (cerium, lanthanum, or a combination thereof). The core may also comprise an organic stabilizer component, a carbon component, and an agglomerate. The organic stabilizer component may comprise an organic molecule or organic polymer bound to one or more Group I or Group II metals. The carbon component may comprise graphite, graphene, carbon black, lamp black, carbon nanotubes, diamond, or a combination thereof. The agglomerate may comprise oxides of one or more Group I or Group II metals, titanium, and manganese.
US12128497B2
An ophthalmic laser surgical system has a built-in imaging sensor for measuring laser focal spot size. An objective lens focuses the laser beam to a focal spot near a reflective surface, scans the focal spot in the depth direction, and focuses light reflected by the reflective surface to form a back-reflected light. A two-dimensional imaging sensor receives a sample of the back-reflected light to generate images of the back-reflected light. During the depth scan, the image contains a well-focused light spot when the laser focal spot is located at a fixed offset distance before the reflective surface, but the light spot in the images is otherwise defocused. The images generated during the scan are analyzed to find the smallest light spot size among the images. The laser focal spot size is then calculated from the smallest light spot size using a magnification factor which is a system constant.
US12128496B2
A casting mold (6) consists of two mold halves (4, 5), which are intended for setting up on both sides of the welding groove (3) between two rail ends (1, 2) to be connected, thereby forming a casting space (8) representing a cross-sectional profile of the rails. For sealing the casting space (8) between the rail bodies on both sides of the welding groove (3) and the wall portions (9, 10) of the casting mold (6) that are facing this welding groove, inserted in gaps (11, 12) are strips consisting of a compound at least containing expandable graphite, which as a result of heat being supplied during a preheating process expands and forms a reliable seal. In comparison with using filler sand at this point, there is the advantage that a much smaller quantity of compound has to be carried along when working on the laid track.
US12128479B2
An orthopedic device, such as an intramedullary nail for internal fixation of a bone and a method of manufacturing the same. The orthopedic device may be formed from a medical grade powder via an additive manufacturing process. The forming process may include heat treating the additive manufactured component and machining the heat treated additive manufactured component to form the orthopedic device. Further, the orthopedic device may be formed to include an internal sensor probe channel that extends within at least a portion of the wall of the device, but which does not protrude through an outer portion of the wall. Embodiments further include a dynamizing intramedullary nail that accommodate adjustments in the relative axial positions of one or more sections of the orthopedic device. The devise may include features in an inner region of the orthopedic device that may alter an elastic modulus of the orthopedic device.
US12128477B2
An additive method of forming a metallic nanoparticle microdot on a substrate is disclosed. The method includes: (A) estimating or obtaining a position of an outlet of a capillary tube at zero height above the substrate (zero-height position); (B) extruding a metallic nanoparticle composition from the outlet at a first height h1 above the zero-height position, including forming a fluid bridge between the outlet and the substrate; (C) optionally lifting the capillary tube relative to the substrate by a height increment of Dh while continuing to extrude the metallic nanoparticle composition from the outlet; and (D) rapidly lifting the capillary tube to separate the outlet from the fluid bridge.
US12128476B2
A system and method of manufacturing an aluminum fuel cell cradle includes providing a negative cast mold having cavities to form the cradle having a length greater than a width to define a longitudinal axis and providing a feeding mechanism disposed about the mold and in fluid communication with the cavities thereof. The feeding mechanism includes primary risers connected to and in fluid communication with the cavities. The method further includes melting a first metallic material to define a molten metallic material, moving the mold to a vertical orientation about the longitudinal axis while feeding molten metallic material through the runner to the cavities, and moving the cast mold to a horizontal orientation. A second solidification time in the risers is greater than a first solidification time in the mold such that shrinkage of the solidified metallic material occurs in the risers away from the mold.
US12128474B2
A method for preparing a negative pressure film-covering frozen sand mold includes: directly obtaining a mold cavity of a sand mold through numerically controlled machining of a frozen sand blank; covering a surface, brushed with a thermal insulation coating, of the mold cavity of the sand mold with a softened thin film, and covering an outer surface of the sand mold with a back film to seal a sand box; fixing the frozen sand mold in an air extraction sand box with a vacuum chamber, and extracting air through a vacuum pump, so that the thin film tightly adheres to the sand mold through vacuum suction force; and closing the box to obtain an integral sand mold, and pouring a casting at room temperature or low temperature under negative pressure. The method is environment-friendly, and the prepared frozen sand mold has high strength and is convenient for sand cleaning.
US12128471B2
An ejecting system for a workpiece from a die cavity in a stamping machine is disclosed. The ejecting system has a spring plunger mechanism to fetch the workpiece from the die cavity of the die platen of the stamping machine. The spring plunger mechanism is provided with a picker which is integrated with a vacuum system to hold the workpiece. Underneath the spring plunger mechanism, there is an actuator, including a positioning sensor, for triggering both synchronous upward and downward movement of the linear actuator to the punch of a die set.
US12128462B1
A method for processing organics includes the introduction of mixed organic and inorganic material into a separator and reducing the material into large and small fragments of inorganic material and a recovered organic stream. Removing a portion of the large fragments of inorganic material from the separator. Transporting the recovered organic stream to a de-pulping machine and processing the recovered organic stream in the de-pulping machine. Removing at least a portion of the small fragments of inorganic material providing a de-pulped organic stream. Depositing the de-pulped organic stream into a de-pulped organics container where the de-pulped organic stream may be post processed into recycled material.
US12128446B1
Disclosed herein are a substrate sorter, an inspection and sorting system having the substrate sorter, and a method for the inspection and sorting system. The substrate sorter includes an annular gripper comprising a rotator and a plurality of vacuum applicators concyclically disposed around an axis, a carrier operable to move a substrate towards the rotator and into a loading region below the rotator, and an actuator coupled with the annular gripper and operable to rotate the rotator about the axis relative to the plurality of vacuum applicators while one or more of the plurality of vacuum applicators hold the substrate against the rotator.
US12128442B2
Coating compositions for coating fluid handling components, and related methods, may include in some aspects a coating composition having a trifunctional silane, a silanol, and a filler. The coating composition may be applied to a surface of a fluid handling component that is configured to be exposed to a fluid. The coating composition may be applied to at least partially cover or coat the surface. The coating composition may be configured to chemically bond with a cured primer composition that includes an epoxy.
US12128439B1
Embodiments of the present disclosure discloses an adjustable pressure cleaning machine including a host machine and a water gun. The main machine is provided with a main control circuit board, the water gun is provided with a remote controller. The main control circuit board is connected to the remote controller through communication; an outer shell of the host machine is provided with a pressure gear button and a power source button, the remote controller is provided with a remote control gear button. The main control circuit board includes a power source module, a button control module, and a voltage control module; the power source module is connected to an external power source to provide working voltage to the button control module and voltage control module. An output end of the voltage control module is connected to a power input end of a motor of the cleaning machine.
US12128432B2
Disclosed is a height and rotational adjustment system for a spray gun used in a line striper comprising: (a) a control device to set a dimension of a line to be sprayed and set an angle at which the line is to be sprayed; (b) a spray gun mount bar having a gun holder assembly to retain a spray gun; (c) a height adjustment mechanism coupled to the spray gun mount bar; (d) an angular adjustment mechanism coupled to the spray gun mount bar; and wherein the control device transmits signals (e.g., wirelessly) to: (1) the height adjustment mechanism to raise or lower the spray gun mount bar to spray the line with the dimension in (a), and (2) the angular adjustment mechanism to rotate, in a clockwise or counter-clockwise manner, the spray gun mount bar to spray the line at the angle in (a).
US12128426B2
A base unit and a modular centrifugal separator are disclosed. The base unit includes a stationary frame, a rotatable member, and a drive unit. The rotatable member delimits an inner space being configured for receiving at least one part of an exchangeable separation insert therein. The rotatable member is provided with a first opening at a first axial end configured for a first fluid connection of the exchangeable separation insert to extend through the first opening. The rotatable member includes a second opening at a second axial end configured for a second fluid connection of the exchangeable separation insert to extend through the second opening.
US12128415B2
An apparatus for loading and imaging a microfluidic chip can comprise a housing having walls that define a vacuum chamber and a first receptacle disposed within the vacuum chamber, the first receptacle defining a space for receiving one or more microfluidic chips. The apparatus can also include a negative pressure source, a light source, and an optical sensor coupled to the housing. The negative pressure source can be configured to reduce pressure within the vacuum chamber, the light source can be positioned to illuminate at least a portion of the space for receiving the chip(s), and the optical sensor can be positioned to capture an image of at least a portion of the space for receiving the chip(s).
US12128411B2
An electrowetting system is disclosed. The system includes electrodes configured to manipulate droplets of fluid in a microfluidic space. Each electrode is coupled to circuitry operative to selectively apply a driving voltage to the electrode. The system includes a dielectric stack including a first dielectric pair comprising a first layer having a first dielectric constant and a second layer having a second dielectric constant. The second dielectric constant is larger than the first dielectric constant. The dielectric stack includes a second dielectric pair comprising a third layer having a third dielectric constant and a fourth layer having a fourth dielectric constant. The fourth dielectric constant is larger than the third dielectric constant. A ratio of a thickness of the fourth layer to a thickness of the third layer (T4:T3) is in the range from about 2:1 to about 8:1. The second dielectric pair is thinner than the first dielectric pair.
US12128409B2
There is provided a microchip comprising: a main flow path through which a liquid containing microparticles flows; and a branch flow path that branches from the main flow path. A cross-sectional area of a portion of the main flow path is substantially constant up to a branch start position or decreases toward the branch start position, and a radius of curvature R of a side wall that connects a side wall of the main flow path and a side wall of the branch flow path is 0.5 mm or less and more than 0 mm.
US12128407B2
Microfluidic chips and cartridges and systems that include such chips are disclosed. In some embodiments, the chips include a microfluidic channel disposed in a substrate with the channel comprising at least one expansion region. The channel is configured to generate a vortex within the at least one expansion region in response to fluid through the microfluidic channel to trap cells or particles. The substrate in which the channel is formed may be relatively rigid to resist deformation.
US12128406B2
A biological fluid filtration system for scanning a biological fluid so as to filter potentially undesirable constituents from the biological fluid for therapeutic or diagnostic purposes. The biological fluid filtration system generally includes a fluid receiving device adapted to receive a biological fluid. A valve including an inlet, a first outlet, and a second outlet is fluidly connected to the fluid receiving device. The biological fluid within the fluid receiving device is scanned by a scanner to produce scanned data relating to the biological fluid. A control unit in communication with the scanner and the valve receives the scanned data and controls the valve based on the scanned data. The valve is controlled to direct the biological fluid through either the first or second outlet of the valve depending upon the constituents of the biological fluid identified by the control unit.
US12128404B2
A microfluidic test system is disclosed. The system includes a test substrate including parallel channels and reaction chambers. The reaction chambers are adapted to accommodate optical transmittance, absorbance and reflectance testing. The movement of the fluid within the system is controlled and synchronized in real time with the optical measurements of the reagents and analytes within each individual reaction chamber. The optical testing of each reaction chamber is customized regarding the color and intensity of the source light. The system includes an easy-to-use applicator for the capture of the test fluid and a fully automated measurement and test system. The microfluidic test system may be incorporated into clothing or apparel such as in a diaper. A device and method are also disclosed.
US12128398B2
This dispenser comprises a syringe (52), a piston (56) that moves inside the syringe (52), and a tip-connecting part (51) for connecting the syringe (52) with a tip (53). The tip-connecting part (51) comprises: a first flow channel (61); a second flow channel (62); two grooves (54a) and (54b), which are each provided over the entire circumference of the side surface of the distal end where the tip (53) is to be installed and are mutually separated in the tip (53) insertion direction; and elastic bodies (55a) and (55b), which are respectively provided in the two grooves (54a) and (54b). The first flow channel (61) extends in the movement direction of the piston (56) and passes through the tip-connecting part (51). The second flow channel (62) is separated from the first flow channel (61), and one end is exposed between the two grooves (54a) and (54b).
US12128393B2
Provided are a denitration catalyst regeneration method and a denitration catalyst regeneration system, which are capable of recovering denitration performance to a high level and reducing the SO2 oxidation rate of a catalyst. A denitration catalyst regeneration method according to the present invention includes: a chemical solution cleaning step for immersing a denitration catalyst in a chemical solution containing a fluorine compound and an inorganic acid; a step for extracting the denitration catalyst from the chemical solution; and a finish washing step for washing the denitration catalyst extracted from the chemical solution with a finish cleaning solution containing an organic acid.
US12128389B2
The disclosure generally provides zeolites having the CHA crystalline framework and methods of preparing the same. Provided herein are CHA zeolites containing intergrowths, a controlled framework aluminum distribution, or both. Further provided are CHA zeolites wherein crystals of the zeolite material have a predominantly flake-like morphology as determined by scanning electron microscopy (SEM). Further provided are catalyst compositions, articles, and systems including CHA zeolites promoted with a metal.
US12128382B1
Devices, methods, and systems for carbon dioxide (CO2) sequestration using a cellulose nanofiber (CNF) aerogel, having a monolithic structure. The monolithic structure includes an aerogel matrix, a plurality of crosslinked CNFs, and a plurality of cellulose nanocrystal acetone (a-CNC) suspension particles, where the plurality of crosslinked CNFs and the plurality of a-CNC suspension particles are dispersed throughout the aerogel matrix. Systems and methods for CO2 sequestration include locating a CO2 producing process, separating, using a first membrane system, a feed stream into a mixed solid and liquid stream and a first gas stream and separating, using a second membrane system, the first gas stream to produce a second gas stream and a CO2 rich stream. Systems and methods further include directing the CO2 rich stream to a cellulose nanofiber (CNF) aerogel unit and adsorbing CO2 from the CO2 rich stream.
US12128375B2
The present invention relates to a method for preparing a metal powder intended for an additive manufacturing process, of the type that involves scanning a bed of powder by a near-infrared laser beam, characterized in that the method comprises: an initial step for selecting a powder, which has an optical reflectivity of higher than 70% for a wavelength ranging between 800 and 1500 nm; then a step for treating said powder, which is different from particle grafting, and which induces a physical and/or chemical surface modification of the grains of said powder, making it possible to lower its optical reflectivity, at the given wavelength. The invention also relates to the use of such a powder, the grains having, after treatment, a median grain size d50 of between 5 and 50 μm.
US12128373B2
A mixer for combining food constituents into a homogeneous mass includes an eccentric drive mounted on a mixing head of the mixer, where the eccentric drive is configured to rotate around a central axis of a mixing area and rotate an offset rotational axis of a drive shaft in an orbit about the central axis of the mixing area. An angled beater attachment for the mixer further includes a top mounting portion operably coupled to the drive shaft of the stand mixer, a bottom beater portion disposed above the mixing area, and a beater support member operably coupled with a support shaft of the bottom beater portion. The bottom beater portion is driven by the drive shaft about an angled rotational axis that extends at an acute angle relative to the central axis of the mixing area.
US12128366B2
A monolayer membrane containing gelling polymer particles having at least one of a basic functional group and an acidic functional group, and having a thickness of less than 5 μm. A composite having a porous carrier and gelling polymer particles having at least any one of a basic functional group and an acidic functional group and filling up the surface pores of the porous carrier. The invention can provide a novel material capable of efficiently separating an acid gas from a mixed gas.
US12128363B2
A membrane having a first outer surface having a plurality of pores in a skin layer and the plurality of pores having a closed perimeter in the skin layer. The membrane having a second outer surface and a porous supporting layer connecting the first outer surface to the second outer surface. The first outer surface of the membrane is a melt-fused skin layer from exposure to ultra-violet light.
US12128362B2
A method is presented for checking the integrity of a hollow-fibre fluid filter, in particular a hollow-fibre dialyzer (1), which is constructed from a plurality of hollow fibres (15) enclosed by a membrane, with the steps of: perfusing the inside or outside of the hollow fibres (15) with a fluid, supplying the outside or inside of the hollow fibres (15) with a gas, wherein the gas has a higher pressure than the fluid, and determining a quantity of the gas which penetrates into the fluid through holes in the membrane. The method is characterized in that, after flowing through the hollow-fibre fluid filter (1), the fluid is channelled through a bubble trap (30), and in that a volume of gas (41) collecting in the bubble trap (30) during a predefined or predefinable reference period is determined. Furthermore, equipment for checking the integrity of a hollow-fibre fluid filter (1) is presented.
US12128356B1
A method for removing hydrogen sulfide (H2S) from a H2S-containing gas composition, including charging an aqueous media to a reactor under continuous agitation, dispersing particles of a composite in the aqueous media to form a composite mixture, continuously agitating the composite mixture, introducing the H2S-containing gas composition to the reactor containing the composite mixture under continuous agitation and passing the H2S-containing gas composition through the composite mixture, and adsorbing and removing H2S from the gas composition by the composite mixture to form a purified gas composition. The composite contains a CuMnAl mixed metal oxide (MMO) and zeolitic imidazolate framework-67 (ZIF-67) nanoparticles. The ZIF-67 nanoparticles are dispersed between layers of the CuMnAl MMO.
US12128355B2
The present invention relates to the conversion of flue gas to valuable products, in particular to the conversion of carbon dioxide in flue gas to liquid fuels and valuable carbons in a carbon negative manner.
US12128350B2
A water-lean carbon dioxide absorbent according to the present invention comprises a cyclodiamine and a polyalkylene glycol alkyl ether and further comprises an alkanolamine, wherein the absorbent shows an excellent reaction rate with carbon dioxide, is resistant to degradation due to oxygen and heat, and can greatly reduce energy consumption due to latent heat of water when regenerated, and thus leads to a water-lean carbon dioxide absorbent with improved regeneration efficiency.
US12128343B2
The invention relates to a filter arrangement comprising a filter cartridge, having an opening and a wall which is formed by a filter medium and has an inner side delimiting a clean side of the filter and an outer side delimiting a raw side of the filter, a fan for conveying air to be purified first through the wall and subsequently through the opening of the filter cartridge, and a purification device, which is configured to convey a jet of compressed air through the opening into the filter cartridge and through the wall out of the filter cartridge, for conveying dirt away from an outer wall of the wall. The invention also relates to a method for detecting a leak of a filter cartridge, wherein the filter cartridge has an opening and a wall which is formed by a filter medium and has an inner side delimiting a clean side of the filter and an outer side delimiting a raw side of the filter.
US12128340B2
Various embodiments relate to a filter element. The filter element includes a first filter end, second filter end, filter media, and filter frame. The second filter end is disposed axially away from the first filter end. The filter media extends axially between a first filter end and a second filter end. The filter frame is adjacent to the first filter end. The filter frame includes a first frame end, a second frame end, a first frame endwall, a second frame endwall, a first frame sidewall, and a second frame sidewall. The second frame end is disposed axially away from the first frame end. The first frame endwall extends axially away from the first frame end toward the second frame end. The second frame endwall extends axially away from the first frame end toward the second frame end. The second frame endwall is disposed longitudinally away from the first frame endwall.
US12128339B2
A filtering material for air filters, the filtering material including a base material; and an enzyme-containing antibacterial material, an inorganic anti-allergenic material, and a fungal inhibitor, all being supported on the base material.
US12128335B2
The present invention relates to a filter panel (1) intended for a drum filter (2), said filter panel (1) having multiple filter holes (3) wherein each filter hole (3) has a length L and a width W, wherein at least a substantial amount of the filter holes (3) has a length L which is at least 1.5 times the width W, wherein the filter panel (1) has a free surface area which is higher than 81%, preferably at least 83%, more preferably at least 85%, on a side of the filter panel (1) intended to be in contact with a filter cloth of the drum filter (2).
US12128329B1
Solid phase extraction (SPE) disks are manufactured by introducing a series of components and/or liquid suspensions into a mold and evacuating the liquid to form a cohesive filter or SPE disk. After all the free liquid has been substantially removed, the SPE disk is removed from the mold and dried. SPE disks are for use in analytical chemistry procedures.
US12128326B2
A water attraction having one or more inflatable areas and/or features for reducing turbulence of water flow over a ride surface is disclosed. The water attraction includes a ride surface, a water delivery section, and a recovery section. The water delivery section provides water flow on the ride surface. The ride surface may include the assembly of multiple segments and may be fully or partially inflatable. The water delivery section may include one or more water delivery mechanisms, for example, nozzles. A water delivery mechanism may deliver a water flow different from the water flows from other water delivery mechanisms.
US12128323B2
A flipper system for retrofitting existing flippers of a pinball game which rotate in operative engagement with a solenoid, with new flippers. The new flippers have an opening which is removably engageable upon an engagement end of a rotatable actuator shaft and can include hollow cavities within a metal body of the new flipper. An improved connection to the existing solenoid is provided by inclusion of a actuator shaft and clamp with the system.
US12128319B2
Disclosed are new and innovative methods and systems for coordinating a game having a plurality of players. One of the methods comprises: enabling each of the plurality of players to create a team of champions; and creating a one or more real-time battles between a plurality of human players.
US12128317B2
A computer realizes: a management function for managing first management information and second management information as information for managing game media having assigned thereto medium identifiers that are common for each same kind, the first management information indicating the medium identifiers and the number of game media possessed by a player, and the second management information indicating the medium identifiers and usage periods of game media having the usage periods set therefor; a determination function for determining game media available to the player based on the first management information and the second management information; and a set creation function for creating a medium set that includes a plurality of game media and that can include a plurality of game media of the same kind, based on an operation performed by the player to select from the game media available to the player, determined by the determination function.
US12128313B2
This specification provides a computer-implemented method, the method comprising obtaining a machine-learning model. The machine-learning model is being trained with expert data comprising a plurality of training examples. Each training example comprises: (i) game state data representing a state of a video game environment, and (ii) scored action data representing an action and a score for that action if performed by a video game entity of the video game environment subsequent to the state of the video game environment. An action is performed by the video game entity based on a prediction for the action generated by the machine-learning model. The method further comprises determining whether the action performed by the video game entity was optimal. In response to determining that the action performed by the video game entity was suboptimal, a healed training example is generated. The healed training example comprises: (i) the state of the instance of the video game environment, and (ii) healed scored action data indicative that the action performed by the video game entity was suboptimal. The machine-learning model is updated based on the healed training example.
US12128308B2
System, process and device configurations are provided for game environment customized generation of gaming music. A method can include detecting a gameplay location for a game environment of an electronic game and at least one environmental parameter for the gameplay location. Gaming music based may be updated based on the at least one environmental parameter to account for one or more of proximity to gaming objects and landscape descriptions for openness and enclosed spaces. Gameplay locations may be detected based on a mapping of the game environment for two-dimensional (2D) and three-dimensional (3D) mapping. Gaming music may be updated to adjust parameters for generating the gaming music based on emotional impact data of the location and direction of one or more objects in the gameplay location relative to a user character. Coordination of music and game environments may provide an immersive and intuitive sense of objects.
US12128282B2
The present application discloses an accessory for items of sporting equipment. Implementations may provide an accessory comprising a structure configured to be affixed to a first end of an item of sporting equipment meant to be swung or rotated, such as a baseball bat, lacrosse stick, or tennis racquet. The addition of the accessory results in movement of the center of mass of the sporting item. Implementations may be varied in weight and dimension such that the center of mass of the sporting item is moved to a location optimal for the demands of the sport and individual athletes' needs. Implementations may also provide for modifiable weight or dimension of the accessory.
US12128274B2
According to an aspect of an embodiment, an adjustable pull-up bar may include a bar, a structural mount, a lever arm, and a control system. The structural mount may be sized and configured to be attached to a stationary object. The lever arm may include a proximal end and a distal end. The proximal end may be coupled to the structural mount. The distal end may be sized and configured to support the bar. The control system may be configured to adjust the height of the bar relative to the ground.
US12128268B1
A hands-free human exercise apparatus and method, including a method of use. The stretching apparatus and method promote beneficial stretching of ambulatory muscles for a broad spectrum of users, to maintain and increase flexibility and dexterity, improved joint health, mobility, or pain management, and facilitating greater balance and proprioception and stimulating rehabilitation. The apparatus includes a multi-directional, multi-configurable, and adjustable harness comprising a one or dual strap configuration having a unique multi-joint activating foot anchor. The apparatus and method facilitate stretching of a single leg, or both legs, through the ambulatory chain of muscles and joints, and with the foot anchor exploiting the flexion of the spine, full extension of the leg and pelvis, and the full flexion of the user's foot.
US12128265B2
A fire protection sprinkler system includes a horizontal barrier that covers two adjacent racks, and the vertical flue space between the racks. The horizontal barrier is provided at a predetermined height, and has a width that is at least equal to a width of the rack, and a depth that is at least equal to a sum of a depth of the rack, a depth of the other rack, and a depth of the vertical flue space. In addition, the horizontal barrier is a sheet having one or more apertures. The system also includes a rack level fire protection sprinkler connected to a fluid supply conduit, and being disposed in the vertical flue space below the horizontal barrier. The rack level sprinkler has a K-factor of 11.2 gpm/(psi)1/2 or greater, and is vertically spaced from commodities stored on the rack and the other rack covered by the horizontal barrier.
US12128235B2
This disclosure is directed to devices, systems, and techniques for controlling electrical stimulation therapy. In some examples, a medical device includes stimulation generation circuitry configured to deliver a first stimulation pulse to a patient, sensing circuitry configured to sense the first stimulation pulse, and processing circuitry. The processing circuitry is configured to determine that a value of a characteristic of the sensed first stimulation pulse exceeds a target stimulation pulse value and responsive to determining that the value of the characteristic of the sensed first stimulation pulse exceeds the target stimulation pulse value, change a first value of a parameter to a second value of the parameter that at least partially defines a second stimulation pulse deliverable by the stimulation generation circuitry after the first stimulation pulse was sensed.
US12128222B2
A safety housing based implant/medicament injecting system. The system includes a needle assembly prefilled with an implant/medicament for injection and an injecting needle/cannula, a housing for accommodating the needle assembly under usual bias inside said housing, a plunger means having a plunger rod configured for stage-wise forward motion including an initial-injecting plunger forward motion with the needle assembly within the housing to first engage the needle assembly with the housing and a subsequent continuing-injecting plunger forward motion independent of the needle assembly for injecting the implant/medicament. The needle assembly configured to return post-injecting to be secured inside said housing blocking any subsequent use thereof.
US12128221B2
A mixing device configured to hold two containers, each having a separate medicament component disposed therein. A fluidic channel is provided that upon creating fluidic communication with each container once seals about each container are opened. Then a transfer mechanism can transfer the medicament components from one container to the other container until ready to be delivered or transferred through the fluidic channel through a delivery assembly.
US12128220B2
A data collection device for attachment to an injection device and for collecting medicament dosage information therefrom.
US12128216B2
Methods, systems, and apparatuses for integrating medical device data are disclosed. In an example embodiment, a server receives infusion therapy progress data that is generated by an infusion pump and renal failure therapy progress data that is generated by a renal failure therapy machine. The server also receives physiological data that is generated by at least one physiological sensor. The server determines fluid balance data based on a difference between the infusion therapy progress data and the renal failure therapy progress data. The server stores the fluid balance data in conjunction with hemodynamic information from the physiological data to a patient's medical record.
US12128209B2
A computing device comprises a memory and a data interface for connecting to a corresponding interface in a storage assembly. The memory comprises instructions which, on connection with the storage assembly, cause a processor of the storage assembly to: detect, using a device sensor of the storage assembly, one or more medicament delivery devices stored in the storage assembly; and display, on a display screen provided on the storage assembly, information relating to a medicament stored in the storage assembly.
US12128206B2
A disclosed antimicrobial medical device includes a fluid transfer device configured to couple between a patient and a fluid reservoir, a fluid pathway extending through the fluid transfer device, a first electrode coupled to the fluid transfer device, and a second electrode coupled to the fluid transfer device and spaced apart from the first electrode. The first electrode includes a first conductive material and the second electrode includes a second conductive material different from the first conductive material. The second electrode is configured to form a galvanic cell with the first electrode.
US12128204B2
Systems and methods are adapted for treating the carotid artery. The systems include interventional catheters and blood vessel access devices that are adapted for transcervical insertion into the carotid artery. Embodiments of the systems and methods can be used in combination with embolic protection systems including blood flow reversal mechanisms, arterial filters, and arterial occlusion devices.
US12128201B2
An oral delivery capsule device for delivering an active agent to a part of a gastrointestinal (GI) tract of a subject may include a capsule body configured to travel along the GI tract. The capsule device may include a reservoir configured to contain an active agent for delivery to the GI tract of the subject. The oral delivery capsule device may include an actuation feature configured to provide a delivery force thereby causing the dispensing of the active agent. The oral delivery capsule device may include an actuation control feature configured to prevent actuation of the actuation feature under a first condition and allow actuation under a second condition.
US12128200B2
A system and method to irrigate a user's auditory canal. A fluid can be dispensed from a reservoir through a fluid path and out through openings of a delivery element into the auditory canal. A pump may be used to facilitate the process of dispensing the fluid. The fluid can be delivered to the user's auditory canal for a predetermined period of time. Such a time period may be user selectable. The discharge from the irrigation is removed from the user's auditory canal via a discharge port located on the delivery element. The discharge exits the delivery element and proceeds to a discharge reservoir via a discharge path. A vacuum may be used to generate a negative pressure to facilitate the removal of the discharge from the auditory canal.
US12128199B2
An apparatus is disclosed for an optimized transseptal procedure that reduces the number of devices that are used in order to minimize procedural time, complexity and cost. The apparatus comprises a hybrid dilator that comprises the combined functionality of a transseptal sheath and dilator assembly. The hybrid dilator comprises: a dilator shaft defining a lumen for receiving a crossing device therethrough, a distal tip having an outer diameter which tapers down to an outer diameter of the crossing device for providing a smooth transition and a hub coupled with a side arm coupled to the dilator shaft.
US12128196B2
A protective cover for an affected area of a patient, particularly associated with an insertion site of a catheter or other puncture or opening in a patient's skin, comprising a body portion including an aperture, and a window portion, wherein the body portion and window portion each optionally comprises an antimicrobial composition. Aspects of the present invention provide articles, systems and kits for covering an incision, wound or catheter insertion site with a protective cover, and methods of using and making the protective cover.
US12128195B2
Embodiments of a deployment system may include a catheter having a distal end and a proximal end. An actuator may be disposed at the distal end of the catheter and may be operatively connected to electrical connectors extending longitudinally along the catheter from the proximal end to the actuator. The electrical connectors may be configured for transmission of signals to the actuator. One or more connections may be coupled to the actuator and to a deployable medical device disposed at the distal end of the catheter.
US12128188B2
Embodiments disclosed herein are directed to a dynamic pressure response drainage system including control logic configured to enable measuring of residual fluid disposed within the drainage lumen. The residual fluid volume is measured by detecting the magnitude of the dynamic pressure response in the system containing the residual fluid when a sudden displacement (e.g. increase or decrease) of air volume occurs inside the system. The pressure burst magnitude is related to the pressure needed to move the mass of fluid, thus the fluid volume can be calculated from measurements of the burst pressure. The magnitude of the measured air pressure exhibits a dynamic pressure response corresponding to the mass of fluid in the tube. Either positive or negative pressure bursts can be used to produce and measure the corresponding positive or negative dynamic response spike pressure.
US12128187B2
A method can be utilized to reduce the kinetosis effect in passengers of motor vehicles having an autonomous and/or semi-autonomous driving mode. By means of a display unit, an image generated from image data is displayed to at least one passenger in a display area of the display unit while the motor vehicle is moving. The method may involve estimating a future change in an acceleration of the motor vehicle and modifying the image data based on the estimated future change in acceleration by way of a correction algorithm such that an effect of a relative movement between the displayed image and the passenger is reduced.
US12128184B2
An air delivery conduit for conveying breathable gas from a positive airway pressure device to a patient interface includes a tubular wall structure constructed from a textile material. A reinforcing structure may be provided to the wall structure that is structured to prevent kinking or collapsing of the wall structure. The wall structure may include a warp having a plurality of lengthwise textile warp threads arranged in a circle and a weft having a textile weft thread that is woven through the warp threads.
US12128183B2
Patient interface components and/or associated head gear and adjustment systems improve sealing and/or patient comfort and/or ease of use. The interface includes an inflating or ballooning seal. The headgear assembly can be connected to the interface with an elastic component and an inelastic component. The elastic component enabling a course fitting of the interface to the patient and the inelastic component enabling a final fitting of the interface to the patient.
US12128180B2
Deformable valves and atomizer designs for a vaporizer (e.g., electronic cigarette). The vaporizer may be used for vaporization of liquid and/or organic material. The vaporizer may enable enhanced flow control of fluid and may generate high quality and quantity of vapor efficiently. In some instances, flow path of the vaporizer may allow bulk fluid flow, e.g., in contrast to capillary flow, to deliver fluid to a vicinity of the vaporizer. In some instances, the vaporizer may utilize improved atomizer designs for vaporizing devices, where said designs can be configured optionally, with various embodiments of a breath-modulating deformable valve.
US12128177B2
A blister packaging for a pharmaceutical cartridge or capsule and methods of forming same are disclosed.
US12128176B2
The present invention provides for the integration of drug dispersion methods into a drug or medicine delivery system. The drug dispersion methods used include shear (e.g., air across a drug, with or without a gas assist), capillary flow or a venturi effect, mechanical means such as spinning, vibration, or impaction, and turbulence (e.g., using mesh screens, or restrictions in the air path). These methods of drug dispersion allow for all of the drug in the system to be released, allowing control of the dosage size. These methods also provide for drug metering, fluidization, entrainment, deaggragation and deagglomeration. The present invention also provides for the integration of a drug sealing system into the device. The drug sealing system provides a way of blocking the migration of drug from one area of the package to another. The drug seal system can also provide a method of tightly containing the drug until the package is opened, of directing airflow through the package and of managing and containing the drug during the package/device manufacturing process.
US12128170B2
Disclosed herein are embodiments of a wound treatment apparatus with electronic components integrated within a wound dressing. In some embodiments, a wound dressing apparatus can comprise a wound dressing. The wound dressing can comprise an absorbent material, an electronics unit comprising a negative pressure source, the electronics unit integrated within the wound dressing and at least partially encapsulated by a flexible film. The electronics unit can include translucent or transparent components that allow light to travel through to reach adhesives or coatings on the electronic components that would otherwise be obscured.
US12128163B2
The invention relates to an air treatment apparatus for a domestic appliance, with at least one air flow device being provided, by means of which an air flow into and/or out of the air treatment apparatus can be generated, the air flow passing through at least one treatment device, and the air treatment apparatus having a closure device by means of which the air treatment apparatus can be sealingly closed.
US12128156B2
The present invention generally relates to an orthopedic implant. Specifically, the present invention relates to an implant that incorporates a purposefully designed material that optimizes bony ingrowth combined with a support material configured to provide structural integrity.
US12128154B2
The present invention has a special filling (WIE) property parameter value developed using microrheology technology, and thus exhibits improved high viscoelasticity flow properties, has low mobility when injected into skin whilst still maintaining the shape thereof, and thus has excellent soft tissue restoration properties, for example for the cheeks, breasts, nose, lips or bottom, and excellent volume expansion and wrinkle alleviation properties.
US12128153B2
Described herein is a decontamination device for use in vehicle applications. The decontamination device includes a device body and an ultraviolet (UV) light, and the decontamination device is 12-24 inches in length and has a narrow form factor for fitting into crevices and nooks of a vehicle. The UV light includes a first UV light source disposed on a first side of the device body and a second UV light source disposed on a second side of the device body and that is opposite the first side. The first and second UV light sources are coupled to the device body and configured to move together relative to the device body. The first UV light source is operable to emit light in an opposite direction than light emitted from the second UV light source.
US12128152B2
Aspects of the present disclosure relate to systems and methods for injection and retraction of a fluid. The system includes a switch configured to be activated, wherein activation of the switch activates an electrical control system. The system further includes a linear actuator that interfaces with the electrical control system. The electrical control system causes the linear actuator to depress a plunger, keep the plunger depressed for a predetermined time, and retract the plunger after the predetermined time. The system further includes a fluid reservoir engageable with the plunger, wherein the depression of the plunger causes fluid to be injected from the fluid reservoir into a connector and the retraction of the plunger causes fluid to be retracted into the fluid reservoir and out of the connector.
US12128151B2
The invention relates to a disinfection lighting device (10) comprising a first light source (14), wherein the first light source (14) comprises a solid-state light source, wherein the solid-state light source comprises one or more light emitting diodes (14a, 14b), lasers and/or superluminescent diodes; wherein the first light source (14) is configured to generate first light source light having a first spectral power distribution, wherein the first spectral power distribution comprises first light source light (140) in the UV wavelength range and/or visible wavelength range, a second light source (13), wherein the second light source (13) is configured to generate second light source light (130) having a second spectral power distribution different from the first spectral power distribution, wherein the second spectral power distribution comprise in the UV wavelength range, wherein the second light source (13) is arranged at a distance D from the first light source (14), the second light source (13) comprises a light input face (13b) configured in a light receiving relationship with the first light source (13), and the second light source (14) comprises a light exit face (13a), wherein the second light source (13) is transmissive for at least, a major, part of the first light source light (140); and wherein the disinfection lighting device (10) is configured to generate lighting device light comprising the second light source light (130) and the first light source light (140) emanating from the light exit face (13a), wherein the disinfection lighting device (10) comprises a light exit window (12), wherein the light exit face (13a) is the light exit window (12).
US12128148B2
A system for disinfecting an enclosed space includes a housing, ultraviolet (UV) emitters, a sensor to detect occupancy in or entry into an enclosed space, a UV directing mechanism, and a controller. The housing includes an air flow passageway. When the UV directing mechanism is in the closed state, the UV emitters are positioned in the air flow passageway and transmission of UV electromagnetic radiation into the enclosed space is substantially blocked. UV electromagnetic radiation is transmitted into the enclosed space when the UV directing mechanism is in the at least one open state. Disinfection operations can be activated when the UV directing mechanism is in the open state or the closed state. When the UV directing mechanism is in the open state, the disinfection operation is activated when the sensor indicates no occupancy in or no entry into the enclosed space.
US12128141B1
Muco-adhesive, controlled release formulation of levodopa and/or esters of levodopa and uses thereof
The invention provides an oral solid formulation comprising (a) a controlled release component comprising a core comprising levodopa, wherein the core is coated with a muco-adhesive coating and the muco-adhesive coating is externally coated with an enteric coating; and (b) an immediate release component comprising levodopa. The invention further provides a method for making and using the oral solid formulation.
US12128138B2
A mouthwash and method for oral care benefits includes a swishable powder delivery system having a content of at least two types of sugar alcohol particles with different particle size distributions and one or more active ingredients, the powder delivery system being a dry and flowable population of particles suitable for resembling a liquid mouthwash by swishing the powder delivery system, thereby generating fluid in the oral cavity without adding water.
US12128137B2
Topical pharmaceutical compositions include tazarotene or a pharmaceutically acceptable salt of tazarotenic acid and an oil-in-water emulsion vehicle that forms a lotion. The compositions are used to treat skin diseases, such as acne vulgaris.
US12128136B2
The present disclosure provides microRNA-based therapies using a hydrogel delivery system that provides regenerative approach to myocardial infarction by targeting cardiomyocytes. The hydrogel provides for local and sustained cardiac delivery of microRNAs, such miR-302 mimics that can be used to promote cardiomyocyte proliferation. Also provided are compositions suitable for local and sustained release and methods for intramyocardial gel delivery of a miRNA oligonucleotide.
US12128131B2
Disclosed herein are methods for treating epithelial cysts, including pancreatic cysts, in a subject by intracystic injection of compositions comprising antineoplastic particles, including taxane particles such as paclitaxel particles and docetaxel particles.
US12128128B2
In one aspect, a composition for topical application is provided. The composition comprises a base. Dispersed within the base is elemental silver as a colloidal suspension, and plant extract from at least 6 plants. The plants are selected from the group consisting of Echinacea purpurea, Stellaria media, Aloe vera, Matricaria recutita, Hypericum perforatum, Calendula officinalis, Equisetum arvense, Symphytum officinale, Panax ginseng, Rumex crispus, Arctium lappa, Trifolium pratense, Chelidonium majus, Thuja occidentalis, Urtica dioica, Mahonia aquifolium, and Galium aparine.
US12128126B2
The present invention is in the field of rinse-off conditioner compositions; in particular, relates to rinse-off conditioner compositions with improved conditioning benefits. Silicones are a commonly used conditioning agent and thus improved deposition of silicones is always desired. It is therefore an object of the present invention to provide improved silicone deposition and also improved sensory of hair. It has been found that the above objects can be achieved by a conditioner composition comprising a specific combination of silicones.
US12128123B2
The present disclosure is directed to providing a moldable solid washing agent composition and an article molded from the same. The composition of the present disclosure can be stored easily at room temperature for a long time. It is applicable to a system that can be manufactured on site and can satisfy customer needs because it can be molded immediately by a simple method and the shape, size, etc. can be controlled. In addition, the solid washing agent composition disclosed in the present specification has superior compatibility with water.
US12128122B2
The present disclosure provides recombinant nucleic acids comprising one or more polynucleotides encoding one or more cosmetic proteins (e.g., one or more human collagen proteins); viruses comprising the recombinant nucleic acids; compositions (e.g., cosmetic formulations) comprising the recombinant nucleic acids and/or viruses; methods of their use; and articles of manufacture or kits thereof.
US12128115B2
A method of performing a chelating reaction comprising contacting a divalent metal with a compound of Formula (I): or a salt thereof wherein: each of R1-R4 is independently selected from the group consisting of CH2COORa and CH2C(═O)NHRa; each of R5-R12 is independently selected from the group consisting of H and -L-X; each Ra is independently selected from the group consisting of H and -L-X; each L is independently selected from the group consisting of absent and a linking group; and each X is a biological agent; and wherein the contacting occurs at a temperature below about 40° C. to form a chelated composition.
US12128105B2
The disclosure describes compounds of Formula Ia, which in non-limiting aspects contain an asialoglycoprotein receptor (ASGPR) binding moiety and an anti-β1AR binding moiety. Compounds of Formula Ia are useful in preventing, treating, and/or ameliorating heart failure in a subject when administered in therapeutically effective amounts.
US12128103B2
Methods are provided for the adjuvant treatment of operable HER2-positive primary breast cancer in human patients by administration of pertuzumab in addition to chemotherapy and trastuzumab. The methods reduce the risk of recurrence of invasive breast cancer or death for a patient diagnosed with HER2-positive early breast cancer (eBC) compared to administration of trastuzumab and chemotherapy, without pertuzumab.
US12128102B2
The invention relates to COnditional Bispecific Redirected Activation constructs, or COBRAs, that are administered in an active pro-drug format. Upon exposure to tumor proteases, the constructs are cleaved and activated, such that they can bind both tumor target antigens (TTAs) as well as CD3, thus recruiting T cells expressing CD3 to the tumor, resulting in treatment.
US12128091B2
A food supplement is disclosed that comprises an extracellular matrix composition of hydrolyzed collagen, hyaluronic acid and glucosamine, ascorbic acid and, optionally, a cannabinoid composition. The food supplement can be given to pet animals for the relief of or prophylaxis of degenerative joint diseases, such as arthritis.
US12128090B2
The present invention relates to a method for prophylactic treatment of spontaneous bleeding in a subject with severe von Willebrand Disease comprising administering a therapeutic amount of recombinant von Willebrand Factor (rVWF) to the subject.
US12128089B2
Stable injectable compositions comprising glucagon or a pharmaceutically acceptable salt, solvate, or hydrate thereof are disclosed, which comprise (a) a therapeutically effective amount of glucagon; (b) at least one pharmaceutically acceptable solvent; (c) at least one stabilizing agent; (d) at least one sugar; and (e) optionally, at least one pharmaceutically acceptable excipient; wherein said injectable solution is stable and ready-to-use, and wherein pH of the said solution ranges from 3.8 to 4.2. Preferably, the composition is provided in a sealed container, e.g., an ampoule, a vial, a pre-filled syringe or an auto-injector. Further, stable injectable solutions are disclosed, which comprise glucagon or a pharmaceutically acceptable salt, solvate, or hydrate thereof, and which are suitable for subcutaneous, intravenous or intramuscular administration. Methods for manufacturing stable injectable solutions of glucagon are also disclosed.
US12128088B2
This disclosure relates to treating a connective tissue injury. The treatment involves injecting, or otherwise administering, a therapeutic composition into an animal, such as a human being, in need thereof. The therapeutic composition may contain transforming growth factor beta 1 (TGF-β1) and/or transforming growth factor β2 (TGF-β2), connective tissue growth factor (CTGF), and a pharmaceutically acceptable excipient or a secondary agent.
US12128081B2
A process for obtaining enriched fractions of assets from the genus Artemisia, enriched fractions obtained by the process and bioactive composition having fraction enriched from Artemisia. The process uses extraction with supercritical fluid in which the differential consists of sequential extraction, in an unprecedented association of specific conditions and steps with an advantageous effect not previously found, thus obtaining enriched fractions of bioactives with different chemical compositions for a given application. The enriched fractions of assets of the genus Artemisia and/or its so-called bioactive compositions having fraction enriched from Artemisia obtained have application mainly in the pharmaceutical and cosmetic fields.
US12128078B2
Disclosed are immunogenic pharmaceutical compositions comprising yeast lysates for inducing cellular immune responses, methods of making immunogenic compositions comprising yeast lysates, methods of treatment comprising administration of said compositions, and kits comprising said yeast lysate compositions. Disclosed immunogenic compositions further comprise an antigen heterologous to the yeast, and may comprise whole yeast and immunostimulatory agents. Induced cellular immune responses comprise cytotoxic T cell activation with specificity to the antigen comprising the immunogenic composition. Various methods of formulation and administration to a patient are described herein, especially wherein the patient suffers from an infectious disease and/or cancer.
US12128077B2
The present invention relates to a bacterial strain having a genetic homology of at least 95% to one or more of the bacterial strains selected from the group consisting of: Weissella viridescens LB10G, which is deposited as DSM 32906; Lactobacillus paracasei LB113R, which is deposited as DSM 32907; Lactobacillus plantarum LB244R, which is deposited as DSM 32996; Lactobacillus paracasei LB116R, which is deposited as DSM 32908; Enterococcus faecium LB276R, which is deposited as DSM 32997; Lactobacillus plantarum LB316R, which is deposited as DSM 33091; Leuconostoc mesenteriodes LB341R; Leuconostoc mesenteriodes LB349R, which is deposited as DSM 33093; Lactobacillus plantarum LB356R, which is deposited as DSM 33094; Lactobacillus plantarum LB312R, which is deposited as DSM 33098.
US12128073B2
The present invention has developed methods of producing a canine-specific therapeutic composition that is clear, safe, and physiologically and biologically active liquid injectable. The tissue processing protocols described herein include methods for processing and cleaning the incoming dark green placentas to produce a clear amnion injectable product while maintaining its physiological and biological properties. Thus, the present invention features canine-specific therapeutic compositions comprising placental-derived materials and methods of use.
US12128067B2
The present invention relates to a nasal solution used for elimination of nasal occlusions, for cleaning of the inner section of the nose and for the treatment of nasal diseases, wherein bicarbonate (HCO3−) is provided with weight proportion between 0.05% and 1.50% and carbonate (CO3−2) is provided with weight proportion between 0.05% and 1.50% as the active substance in the ingredient thereof and it has alkali pH characteristic and preferably it is obtained from alkaline, closed basin natural spring waters.
US12128058B2
Disclosed are novel multi-substituent psilocybin derivative compounds and pharmaceutical and recreational drug formulations containing the same. The compounds may be produced by reacting a reactant psilocybin derivative with a substituent containing compound.
US12128044B2
A fused tricyclic compound and application thereof in medicine, especially as a medicament for the treatment and/or prevention of hepatitis B. Specifically, the present invention relates to a compound having Formula (I) or a stereoisomer, a tautomer, an N-oxide, a solvate, a metabolite, a pharmaceutically acceptable salt or a prodrug thereof, wherein each variable is as defined in the specification. The present invention also relates to the use of a compound having Formula (I) or a stereoisomer, a tautomer, an N-oxide, a solvate, a metabolite, a pharmaceutically acceptable salt or a prodrug thereof as a medicament, especially as a medicament for the treatment and/or prevention of hepatitis B.
US12128036B2
The present invention is related to methods of stabilizing an ophthalmic drug by adding a surfactant and a viscosity enhancer to the ophthalmic drug to create a composition wherein the composition has a viscosity of about 25 centipoise or less at a shear rate of 1/1000 per second at 25 degrees Celsius and a viscosity of about 70 centipoise or more at shear rate of 1 per second at 25 degrees Celsius, filling the composition into a container; and storing the container at a temperature from about 2 degrees Celsius to about 25 degrees Celsius. The present invention is further directed to a container prepared by the methods of the present invention.
US12128033B2
The present disclosure relates to the fields of chemistry and medicine, more particularly to processes for making 4-(2-chloro-4-methoxy-5-methylphenyl)-N-[(1S)-2-cyclopropyl-1-(3-fluoro-4-methylphenyl)ethyl]-5-methyl-N-prop-2-ynyl-1,3-thi-azol-2-amine (Compound 1), pharmaceutically acceptable salts, and crystalline forms thereof, for the treatment of congenital adrenal hyperplasia (CAH).
US12128026B2
This invention provides novel indole, indazole, benzimidazole, benzotriazole, indoline, quinolone, isoquinoline, and carbazole selective androgen receptor degrader (SARD) compounds, pharmaceutical compositions and uses thereof in treating hyperproliferations of the prostate including pre-malignancies and benign prostatic hyperplasia, prostate cancer, advanced prostate cancer, castration resistant prostate cancer, other AR-expressing cancers, androgenic alopecia or other hyper androgenic dermal diseases, Kennedy's disease, amyotrophic lateral sclerosis (ALS), abdominal aortic aneurysm (AAA), and uterine fibroids, and to methods for reducing the levels (through degradation) and/or activity (through inhibition) of any androgen receptor including androgen receptor-full length (AR-FL) including pathogenic and/or resistance mutations, AR-splice variants (AR-SV), and pathogenic polyglutamine (polyQ) polymorphisms of AR in a subject.
US12128024B2
In certain aspects, the invention relates to methods of treating proliferative cervical disorders (such as cervical cancer and cervical dysplasia) and treating virus infection by administering artemisinin-related compounds. In certain aspects, the invention relates to methods of treating a tumor induced by an oncogenic virus, methods of killing or inhibiting a squamous cell carcinoma, and methods of inhibiting the replication of a virus, by administering artemisinin-related compounds.
US12128021B1
Modified release formulations of gamma-hydroxybutyrate having improved dissolution and pharmacokinetic properties are provided, and therapeutic uses thereof.
US12128015B2
Apurinic/apuyrimidinic endonuclease 1/Redox Factor-1 (APE/Ref-1) inhibitors are provided along with methods of using the same. The inhibitor has the structure of Formula I: or a pharmaceutically acceptable salt thereof. n is an integer from 4 to 14, X and X′ are each independently H or OH, and Y and Y′ are each independently H or OH.
US12128011B2
A method involves dissolving a curcuminoid in glycerol to make an administrable solution. An alkali salt is added to the glycerol to increase the solubility of the curcuminoid in the glycerol to more than 20 milligrams curcuminoid per millilitre of glycerol (and up to in excess of 200 milligrams curcuminoid per millilitre of glycerol with the addition of sufficient alkali salt in embodiments). The resulting administrable solution can be administered (such as by way of intramuscular injection) as is without the need of an aqueous emulsion and can be stored for more titan 24 hours without curcuminoid precipitation.
US12128010B2
The present invention is directed to compositions comprising semifluorinated compounds and their use as medicaments for topical administration to the eye.
US12127999B2
The disclosed CPR devices, systems, and methods adjust a compression depth of a compression mechanism to account for chest collapse of the patient receiving CPR. Compression depth can be adjusted up to a maximum depth in some examples. The compression depth can also be adjusted linearly or non-linearly as the zero point or starting position of the patient's chest changes due to chest collapse. Other factors can also be used to adjust the compression depth such as patient parameters that can be observed by a rescuer or sensed by sensors wirelessly connected to or integrated into the system. CPR devices that include active decompression can also use the disclosed techniques for adjusting the chest compression depth as the patient's chest collapses.
US12127993B1
A massager includes a massager main body, a driving source, a vibrating piece, and a vibrating assembly. The massager main body includes an installing portion and a massage portion connected to each other. The installing portion defines an installing cavity. The massage portion defines an accommodating cavity. The driving source is installed in the installing cavity. A first end of the vibrating piece is connected to the driving source and is driven to vibrate. A second end of the vibrating piece extends out of the installing cavity and is located on one side of the massage portion. The vibrating assembly is installed in the accommodating cavity and enables the massage portion to vibrate. The massage portion and the vibrating piece extend into a human body cavity and massage the human body cavity. A length of the vibrating piece is less than a length of the massage portion.
US12127990B2
A gravity compensator applied to a wearable muscular strength assisting apparatus includes a first link configured to extend parallel to a first body portion of a wearer, a second link configured to extend parallel to a second body portion and which is rotatably coupled to an end of the first link, an elastic body, which is fixed at an end thereof to the first link so as to exert an elastic force, which varies according to a length between the two ends thereof, and a connection unit, which is connected an end thereof to the other end of the elastic body and extends in a longitudinal direction of the first link and which is connected at an end thereof to the second link so as to vary a length of the elastic body by relative rotation between the first link and the second link.
US12127989B2
Provided is a system for muscle strength support. The system includes an exoskeleton which is configured to be attached to a body of a human during use of the system, and a control unit for controlling a supportive force provided by the exoskeleton during use of the system.
US12127982B2
A surgical table having a tabletop to be rotatable about a trend axis, the trend axis extending in a transverse direction across the tabletop; and an actuator mechanism coupled to the movable framework and arranged to raise and lower the movable framework relative to the column and to raise and lower the trend axis and to rotate the movable framework about the trend axis, and a control mechanism arranged to control the actuator mechanism to cause (i) the height of the trend axis to be translationally variable within a first dimensional range having a lowermost position, at which the trend axis extends through the column, and an uppermost position, at which the trend axis is above the upper end of the column the trend axis and is spaced at spacing height above the upper end of the column, and, simultaneously and/or independently (ii) the location of the trend axis in a lateral direction orthogonal to the trend axis to be translationally variable within a second dimensional range extending between first and second end positions.
US12127981B2
A goggle includes a frame, a lens, and a roll-off system. The frame has a first lateral end and an opposing second lateral end. The frame defines a lens cavity. The lens is disposed within the lens cavity of the frame. The roll-off system includes a first canister, a second canister, and an actuator mechanism. The first canister is at least partially integrally formed with the first lateral end of the frame. The first canister defines a first interior cavity configured to store a roll of film. The second canister is at least partially integrally formed with the opposing second lateral end of the frame. The second canister defines a second interior cavity configured to receive a strip of film from the roll of film. The actuator mechanism is configured to facilitate selectively dispensing the strip of film from the first canister across the lens to the second canister.
US12127971B2
A catheter includes a working fluid supply path communicating with a source of working fluid. The catheter also includes a working fluid return path communicating with the working fluid supply path to return working fluid from the supply path to the source of working fluid. At least one of the paths is contained in a distal heat exchange region of the catheter, where the distal heat exchange region includes first and second helical paths and is made of a shape memory material.
US12127965B2
In an embodiment, an orthopedic device in the form of a lumbar support includes first and second elongate belt members, an anatomically shaped plate, and a closure system connecting the belt members to the plate. The closure system is arranged to move the belt members relative to the plate, and connects to the belt members via a flexible belt attachment which removably secures to the belt members. The closure system includes tensioning elements corresponding to the belt members, and a pulley system connecting to the tensioning elements. The closure system is slidably mounted to the plate and arranged to the belt members relative to the plate between opposed linear directions. The plate has various contours which provide pressure distribution over a lumbar region of a back. Anatomically shaped and resiliently formed handles secure to the tensioning elements and the belt members.
US12127962B2
A sock device comprising: a first anchor; a sock; a strap, wherein the strap removably secures the first anchor to the sock; and a distributor. The strap can be used to fit through an attachment ring on the first anchor, pulled down towards a user's ankle, and secured to the sock thereby providing temporary flexion to the foot, which stretches the muscles and tendons of the heel region, calf region, and underneath area of the feet to help treat plantar fasciitis. The distributor provides an even distribution of flexion to the entire width of the foot.
US12127956B2
Universal endovascular grafts are provided for evaluation and repair of damaged or aneurismal blood vessels. More particularly, the present invention relates to universal fenestrated and universal branched endografts for repair of blood vessels with branches, methods for implanting the endografts in the vessel and for making connection with one or more branches. The universal fenestrated endografts have a body with a first end, a second end, a first wall, a second wall, and an interior passage or lumen. The body further includes openings in communication with the passage at the first and second ends and one or more lateral fenestrations in communication with the lumen. The body further has a necked portion between the ends and a cannulation member. The universal branched endografts have a tubular body with a main lumen and four branch lumens. A large branch extends from the body. The four lumens are positioned about a circumference of the tubular body.
US12127954B2
An implant removal tool for use in removing an expandable spinal implant device from a patient and a method of use. The tool includes a shaft having a distal end with a plurality of tabs and a central bore having a threaded section with an internal threaded wall. The plurality of tabs may include two curved tabs having blunt distal ends for cooperating with an implant. The threaded section is configured to receive a threaded shaft of an implant and lock the implant thereon for removal.
US12127946B2
A system includes a first prosthesis. The first prosthesis may include a body extending along a length from a first side to a second and including a third side disposed between the first side and the second side. The body may include a pair of spaced apart rails between which a channel is defined. A stem and a first fixation element may extend upwardly from the third side. A method may include coupling the first prosthesis to bone.
US12127945B2
The present disclosure provides a glenoid implant system for a reverse shoulder implant system that includes a glenoid implant having a center post, and also includes an angled baseplate comprising a bone facing surface to face an implant site prepared in a glenoid region of a patient, and an implant facing surface to face and engage the glenoid implant and receive the center post of the glenoid implant, wherein the implant facing surface being at an angle with respect to a centerline of the bone facing surface.
US12127942B2
An augment for supporting an acetabular shell at an acetabulum of a hip bone. In some examples, the augment can include a body having a first surface and a second surface opposite the first surface. The body can extend from a first end portion that is adapted to be fixed to an acetabular shell, to a second end portion. The body can include a first hole and a second hole, each of the first and second holes extending through the body from the first surface to the second surface. The body can be formed of a porous material that promotes boney ingrowth and can further include a trim marker located in between the first hole and the second hole.
US12127915B2
The present invention relates to a wound dressing comprising or consisting of (a) a covering layer; (b) a sheath on the wound facing side of the covering layer, (c) an absorbent core within the sheath, and (d) an adherent layer on the wound facing side of the sheath; wherein the sheath comprises (b1) an adhesive sheath layer, (b2) a proximal sheath layer on the proximal sides of the absorbent core and the adhesive sheath layer and (b3) a distal sheath layer on the distal sides of the absorbent core and the adhesive sheath layer; wherein the adherent layer comprises an opening, and wherein the adherent layer has (i) a wound facing proximal side adapted to adhere to a body part, and (ii) a distal side adhering to an outer rim of the covering layer.
US12127913B2
An absorbent wound dressing (1) comprising a superabsorbent material (13) that is in fluid communication with the surface of a wound to which the dressing is applied when in use. The superabsorbent material (13) is enclosed in an envelope (14,15) having a wound-facing surface that is knitted or woven from a yarn comprising gelling fibres.
US12127912B2
A wound dressing, a method of manufacturing a wound dressing, and a method of treating a patient are disclosed. The wound dressing may include an absorbent layer for absorbing wound exudate; and an obscuring element for at least partially obscuring a view of wound exudate absorbed by the absorbent layer in use.
US12127911B2
A pressure bandage including an elastic sheet having a first coefficient of elasticity and an adhesive side. The pressure bandage may also include a resilient pad having a second coefficient of elasticity and affixed to the adhesive side of the elastic sheet. The elastic sheet has a first predetermined shape that is configured to be applied to a corresponding anatomical location on the body of a patient. The first coefficient of elasticity and the second coefficient of elasticity are related such that, when the elastic sheet is stretched and adhered to the body of the patient, the resilient pad applies a predetermined amount of pressure to the body of the patient.
US12127907B1
A method that includes the step of engaging an orthodontic protection device with a surface within a person's mouth chosen from the group consisting of: a tooth surface; an orthodontic appliance affixed to the tooth surface and a combination of the tooth surface and the orthodontic appliance affixed to the tooth surface. The orthodontic protection device includes an extruded base material that includes an uncured, uncross-linked silicone high consistency rubber base and the extruded base material has at least one dry, powdered hydrophilic polymeric substance on a surface of the extruded base material.
US12127903B2
The present disclosure provides a dental procedure safety device including a face mask and a face shield attached to each other to form a modified face mask shield device, where the face shield overlaps in front of the face mask. The device further includes a dental dam frame including a plurality of nibs projecting outwardly from an outer perimeter of the dental dam frame for attachment of a dental dam membrane, such that a portion of the dental dam membrane is attached over an upper horizontal member of the dental dam frame. An attachment device, positioned over the portion of the dental dam membrane attached over the upper horizontal member, detachably connects to a rear surface of a lower end of the face mask, such that the modified face mask shield device is positioned in front of the attachment device.
US12127896B2
An electronic identification band can be tightly attached to and surrounded around operating room instruments of various types or specifications for wireless identification by appropriately trimming the length thereof and then peeling off a release paper. The electronic identification band includes a protective housing directly formed on a mounting portion of an elongated flexible substrate to encase an RFID unit therein, such that the RFID unit can be isolated from an ambient environment by a simple structure, thereby achieving the protective function and thus significantly enhancing the economic efficiency in manufacturing the electronic identification band.
US12127888B2
The invention relates to an ultrasound system for imaging a volumetric region comprising a region of interest (ROI). The system comprises a probe; an ultrasound wave controlling unit adapted to control ultrasound wave transmission and provide ultrasound image data of the volumetric region; an image processor; and a ROI identifier, which is adapted to generate identification data indicating the ROI within the volumetric region; wherein the ultrasound wave transmission is configurable by a plurality of use cases in response to respective identifiers of said use cases, each use case being associated with a particular imaging procedure and comprising an anatomical model for said imaging procedure; and wherein the ROI identifier is configurable by the respective anatomical models of said use cases. A method of configuring such an ultrasound system is also disclosed.
US12127887B2
The present invention relates to a method for obtaining elastic properties of a soft solid by means of quasi-omnidirectional transverse waves generated by a focused ultrasound beam, with a helical phase profile that produces an acoustic vortex that generates a transverse wave front, not only in the direction perpendicular to the ultrasound beam but also in the same direction as the ultrasound beam. The invention also allows control of the transverse wave front generated, which facilitates the carrying out of elastography studies at different frequencies and increases the amplitude of the transverse waves produced, thereby improving the signal-to-noise ratio.
US12127874B2
Systems and methods are provided for the combination and display of both live and non-live patient images. The features described include collecting angiographic image data, and correlating angiographic image frames to time-varying data relating to the patient's heart cycle. This time-varying data may then be compared with the patient's live heart cycle data so that the collected angiographic image frames can be interlaced within a display of live fluoroscopic images of the patient.
US12127872B2
Embodiments are provided for improved analysis of surgically explanted pathology samples or other varieties of tissue sample by guiding the sectioning of those samples using high-resolution volumetric imaging data. Such imaging data can include micro-CT imaging data. Improved sample imaging and visualization methods facilitate pathological analysis of the sample, guiding the sectioning of the sample to planes most likely to provide highly valuable and accurate data about sample margins relative to tumors or other target structures, tissue type cell morphology or other properties of a tumor or other target structure, or other clinically relevant data that could be missed were the tissue sample not sectioned along such image-guided plane(s). A projector or augmented-reality device can be used to indicate, to a pathologist, the location of structures of interest within the sample and/or the location of a sectioning gig could be detected/controlled relative to a display of the imaging data.
US12127869B2
A protective case for a handheld x-ray emitter device, and a handheld x-ray emitter device protected by the protective case. Conventional handheld x-ray emitter devices include a tube barrel and a trigger handle connected to the tube barrel. The junction where the trigger handle connects to the tube barrel can be a point of structural weakness in the handheld x-ray emitter device. The protective case covers portions of the handheld x-ray emitter device so as to structurally reinforce the junction between the tube barrel and trigger handle, while still allowing the handheld x-ray emitter device to be operated.
US12127861B2
Systems and methods for handling and packaging instruments are fully automated thereby eliminating human handling and increasing accuracy of packaging and labeling of the instruments. One system includes an instrument identification element, an element that determines packaging requirements, an element that creates the packaging such as a labeled peel pouch. The system makes the package including the instrument or instruments. The completed packaging is ready of next steps including sterilization.
US12127860B2
In one embodiment, a method to track cardiac health of a patient is described. The method includes communicating, via a mobile device, to a cardiac device worn by the patient, wherein the cardiac device includes at least one sensor. The method also includes receiving cardiac device data from the cardiac device and filtering the cardiac device data based at least in part on patient logic rules. The method includes pushing the cardiac device data to one or more personnel based at least in part on the patient logic rules.
US12127852B2
The invention is directed to systems and methods that can determine a user's fitness based on a single factor such as oxygen lung volume (pmVO2). A heart rate measurement is conducted on the user after the user performs a physical test specified by a fitness application of the system. The heart rate measurement is converted into a pmVO2 value and compared to pmVO2 values of other individuals. The system assigns the user a fitness grade based on the comparison result. The system further includes an artificial intelligent system that helps the user to move from a grade to a higher grade.
US12127845B2
A method for delivering a liquid allergen to a patient, by dispensing an amount of the liquid allergen into an allergen reservoir. A pliable cap is placed on the allergen reservoir, where the pliable cap has a hole formed therein. The pliable cap is depressed with a finger that is disposed over the hole, thereby motivating a desired amount of the liquid allergen to flow out from the allergen reservoir and into an allergen dispensing well, where the liquid allergen is absorbed by a wettable material. An allergen delivery barb is pressed into the wettable material, so as to receive a dosage of the liquid allergen. The patient is scratched with the allergen delivery barb.
US12127844B2
Disclosed herein are implementations of a method and apparatus for stroke self-detection. The method and apparatus may include a mobile platform for stroke detection. The method may include receiving sensor data. The method may include comparing the sensor data with a baseline test result to determine a test score. The method may include determining a passing test result based on a threshold. The method may include transmitting the results or an alert to one or more of an emergency contact, emergency medical services, a physician, or a telemedicine provider.
US12127832B2
A method of fabricating a wearable device having one or more integrated electronic components, including providing a substrate having an elastomeric material, at least one metal additive, and/or a carbon source additive; forming electrical circuitry within the elastomeric material by structuring one or more electrically conductive traces and plating the one or more electrically conductive traces; and providing the electrical circuitry with a sensor, wherein the sensor is configured to come in direct contact with skin of an individual.
US12127821B2
A measurement device includes a pressure acquisition unit configured to acquire pressure information representing pressure in a pressing cuff, a cuff pressure control unit configured to control, based on the pressure information, the pressure in the pressing cuff during each of a pressurizing step of pressurizing the pressing cuff, a pressurized state maintaining step of maintaining the pressing cuff in a pressurized state after end of the pressurizing step, and a depressurizing step of depressurizing the pressing cuff after end of the pressurized state maintaining step, a blood pressure calculation unit configured to calculate a blood pressure of a user based on the pressure information, and an electrocardiographic measurement unit configured to measure an electrocardiogram of the user during the pressurized state maintaining step.
US12127819B2
A system and method for calibration a system of determining blood pressure based on pulse wave transit time.
US12127815B2
Systems configured to acquire temperature signals from an Abreu Brain Thermal Tunnel (ABTT), to analyze the temperatures signals, and to determine a condition of a human body from the analysis, and a method for doing the same, are described. In addition, systems for application of thermal signals to the ABTT for treatment of conditions are described.
US12127811B2
A patient support for use with a foundation frame is disclosed. The foundation frame includes a first column and a second column. The patient support includes a base beam, a leg support, and a guide. The base beam is coupleable to the foundation frame to be supported by the first column and the second column. The leg support has a first end pivotably coupled to the base beam and a second end spaced apart from the first end. The, guide is coupled to the base beam and to the second end of the leg support. The guide is configured to guide the second end of the leg support along an arcuate path when the leg support pivots relative to the base beam.
US12127809B2
A medical device includes a first link, a second link, and a band. A proximal end portion of the first link is coupled to a shaft. A proximal end portion of the second link is rotatably coupled to a distal end portion of first link about a first axis. The distal end portion of the second link includes a connector coupled to a tool member that is rotatable relative to the second link about a second axis that is non-parallel to the first axis. The first link defines a first guide channel and the second link defines a second guide channel. A distal end of the band is disposed within the first guide channel and the second guide channel, and is coupled to the tool member. The second link is rotatable relative to the first link about the first axis when the distal end of the band is moved.
US12127806B1
An example system may include a processor of a computer node operatively connected to a computer-guided robotic arm configured to manipulate a medical instrument attachable to the robotic arm and comprising a laser beam emitter located at a distal end of the medical instrument; a memory on which are stored machine readable instructions that when executed by the processor, cause the processor to: cause the robotic arm to perform movements comprising extend, retreat or spin, acquire imaging data of a patient concurrent to the movements of the robotic arm, and configure emission parameters of the laser beam based on the imaging data.
US12127805B1
Catheter device and driving system configured to navigate the catheter through complex narrow tissue openings such as lung bronchi pathway openings of 3 millimeters or less. The device comprises a proximal catheter portion containing a hollow torque shaft, with a distal catheter portion connected to the proximal portion connected to this torque shaft. The distal position of the catheter is controlled by at least one steering cable/tensioning cable arrangement. The system uses processor-controlled actuators that simultaneously rotate the torque shaft and the at least one steering cable/tensioning cable in a 1:1 relationship, while also actuating the steering cable. The catheter is tipped by a tool plate, which can be equipped with various sensors and other instruments and connected to the outside via other conduits.
US12127791B1
A computer-implemented method for updating a surgical plan for placement of a joint implant is disclosed. The surgical plan is obtained, including an implant model, an implant size, and an initial value for each of a plurality of placement parameters. At least one knee performance equation is selected from a library based on the surgical plan information, wherein each knee performance equation relates an output response associated with a post-operative influence to the plurality of placement parameters. Each output response is calculated across a range of values for each of a subset of the plurality of placement parameters. A graphical representation of the output response across each range is displayed, and input related to a selected value for each placement parameter of the subset is received. The surgical plan is updated based on the selected values. Devices and non-transitory computer readable media for carrying out the method are also disclosed.
US12127781B2
Jaw members of end effector assemblies include sealing plates configured to direct the amount and flow of energy through the sealing plates. The sealing plates may have a height varying from a minimal height to a maximum height along a width or a length of the sealing plate and/or a sealing surface including at least two impedance zones having different impedance values.
US12127780B2
A method of forming an energy delivery portion of a medical device includes contacting a distal portion of an electrode shaft with an insulating material, and heating the insulating material to couple the insulating material to the distal portion of the electrode shaft to form an insulation tip. The distal portion of the electrode shaft includes one or more surface contours to entrain the insulating material.
US12127779B2
Example methods and apparatuses are disclosed for providing tissue ablation through electrolysis, electroporation, or a combination thereof. A pulse that has an element of decay may be applied to a target for tissue ablation while the decay is modulated. In some examples, apparatus including a controller and switches may be used to modulate the decay and/or selectively apply the pulse to the target. The apparatus may further include resistors and/or other elements to modulate a magnitude of the pulse and/or a slope of a decay of the pulse.
US12127778B2
Devices, systems, and methods for more efficiently ablating tissue with pulsed field ablation energy while minimizing collateral injury to non-target tissue. In one embodiment, a system for ablating tissue at a treatment site comprises: an energy delivery device; and a control unit including: a source of impedance-modifying fluid in fluid communication with the energy delivery device; an energy generator in electrical communication with the energy delivery device, the energy generator being configured to transmit energy to the energy delivery device and the energy delivery device being configured to deliver energy to the treatment site; and processing circuitry configured to control delivery of the impedance-modifying fluid from the energy delivery device to the treatment site. In one embodiment, a method for ablating tissue comprises delivering an impedance-modifying fluid to a treatment site and delivering pulsed field ablation energy to the treatment site.
US12127773B2
An orthopedic fixation system includes an orthopedic implant and a compression insert transitionable between a natural shape and an insertion shape. The orthopedic implant includes first and second plates with insert slots configured to receive therein a portion of the compression insert. The first and second plates secure with a bone in an opposed relationship while being separated by an expansion whereby the insert slots of the first and second plates align across the expansion. The compression insert, in the insertion shape, inserts into the insert slots of the first and second plates such that the compression insert spans the expansion. The compression insert, due to an attempted transition thereof from the insertion shape to the natural shape, delivers energy stored therein to the first plate and the second plate whereby the orthopedic implant affixes the bone.
US12127771B2
A tether tensioner includes a handle assembly, an elongate member extending distally from the handle assembly, and an engaging portion. The handle assembly includes a stationary member, a trigger pivotably coupled to the stationary member, and a spool rotatably supported on the stationary member. The spool is configured to wrap a tether thereabout. The spool is operatively coupled with the trigger such that pivoting of the trigger relative to the stationary member causes rotation of the spool. The elongate member includes a channel configured to slidably receive a tether therethrough. The engaging portion is configured to receive a head portion of a bone screw such that a tether extends from the head portion disposed in the engaging portion to the spool through the channel of the elongate member.
US12127763B2
A surgical access assembly includes a housing, a tubular member, and a valve assembly. The tubular member extends from the housing. The valve assembly is positioned in the housing and includes a centering mechanism, a guard assembly disposed on a first side of the centering mechanism, and an instrument seal disposed on a second side of the centering mechanism. The instrument seal including petals that are arrange in an overlapping arrangement.
US12127762B2
A surgical access assembly includes a cannula, a valve housing attached to the cannula, and a valve assembly positioned in the valve housing. The valve assembly includes a centering mechanism with a hoop and fingers, a ring with a flange at one end of the ring, a retainer having first and second discs, a guard having a frame and flaps attached to the frame, and a seal with petals attached to a support. The guard is at least partially disposed in the first disc and the seal is at least partially disposed in the second disc.
