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发明公开
CN103361743A 一种用于产前诊断的DNA文库构建方法 无效 - 撤回

一种用于产前诊断的DNA文库构建方法
摘要：
本发明提供一种可用于产前诊断的DNA文库构建方法。本发明，直接运用孕妇血浆建库，减少了DNA提取步骤，从而减少了孕妇血浆使用量，同时较少了胎儿DNA含量出现偏差的可能，而且大幅度的减少了DNA文库构建的成本和时间；本发明的另一方面涉及根据上述的任一种制备方法制得的DNA 文库；本发明的再一方面涉及一种DNA 测序方法。该发明具有很好的应用前景。
摘要（英）：

The invention provides a DNA library construction method for prenatal diagnosis. According to the DNA library construction method for the prenatal diagnosis, pregnant woman blood plasma is directly used for library construction, and a DNA extraction step is omitted, so that use amount of the pregnant woman blood plasma can be reduced, at the same time, possibility of deviation of fetal DNA content can be reduced, and cost and time for the DNA library construction are greatly reduced. Another aspect of the invention relates to DNA libraries prepared by any of above preparation methods. The third aspect of the invention relates to a DNA sequencing method. The DNA library construction method has good application prospect.

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