The invention discloses a control method of a vehicle. The control method comprises the following steps of detecting the rotation speed of a driving wheel and the rotation speed of a driven wheel of the vehicle when an engine of the vehicle stays at a starting state and the vehicle stays at a forwarding gear; controlling a speed changer of the vehicle to enter a breakout mode when the rotation speed of the driving wheel is greater than a first speed threshold value, the rotation speed of the driven wheel is smaller than or equal to a second speed threshold value and the vehicle satisfies a preset condition, wherein the first speed threshold value is greater than the second speed threshold value. By adopting the control method, the success rate for the vehicle to get out of trouble can be greatly increased, the safety driving of the vehicle is guaranteed, and convenience can be brought to a user. The invention also discloses a control device of the vehicle and the vehicle with the control device.