The invention discloses a method and device for measuring noise of a four-drive transfer case motor assembly. The device comprises an experiment table and an integrated control system arranged on the experiment table. A silence chamber is fixedly arranged on the experiment table through bolts; the silence chamber is internally and fixedly provided with a support bench; the four-drive transfer case motor assembly is arranged on the support bench; the top portion of the silence chamber is provided with a condenser microphone and an acceleration sensor; the four-drive transfer case motor assembly is connected with the integrated control system through a control line; and meanwhile, the condenser microphone and the acceleration sensor are connected with the integrated control system through signal lines. The measured four-drive transfer case motor assembly is placed in the sealed silence chamber, so that the measured noise source is isolated with the outside world, influence due to environment noise is filtered effectively, and an ideal detection effect is achieved.