The invention discloses a tri-axial base plate drilling machine, and belongs to the technical field of circuit board processing equipment. According to the technical scheme, the key point is that the tri-axial base plate drilling machine comprises a rack, wherein three drilling units are distributed on the rack; upper end surfaces of platforms, which are used for placing a to-be-drilled base plate, on the three drilling units are positioned on the same horizontal plane; the three drilling units are matched for drilling the to-be-processed base plate; one drilling unit is fixedly arranged on the rack; the other drilling unit is connected to the rack through a horizontal transverse regulating mechanism; and the third frilling unit is connected to the rack through a horizontal four-way regulating mechanism. The invention aims to provide the tri-axial base plate drilling machine which is convenient to use, and is good in effect, and the tri-axial base plate drilling machine is used for drilling a base plate.