The invention discloses a ceramic composite middle frame of a mobile terminal. The frame comprises a ceramic frame and a metal middle plate. The ceramic frame and the metal middle plate are connectedthrough a plastic framework. The metal middle plate and the ceramic frame are provided with lap joint structures. Meshing structures are arranged on the two sides of the plastic framework. A meshing structure on one side of the plastic framework is connected with the lap joint structure of the ceramic frame, and a meshing structure on the other side of the plastic framework is connected with the lap joint structure of the metal middle plate. The ceramic composite middle frame is formed by carrying out in-mold injection molding on a ceramic frame and a metal middle plate. The appearance surfaceof the middle frame has the texture that the ceramic is mild like jade and hard and wear-resistant. Local metallization can be achieved in the ceramic frame according to the antenna design requirement, natural design and layout are facilitated, and the overall middle frame is excellent in texture and effect. Meanwhile, the invention further discloses a preparation method of the ceramic compositemiddle frame for the mobile terminal.