发明授权
- 专利标题: NEUE SYSTEME ZUR REGULATION DER GENEXPRESSION
- 专利标题(英): New systems for regulating genetic expression
- 专利标题(中): 新系统的二对基因表达调控
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申请号: EP97944777.8申请日: 1997-08-21
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公开(公告)号: EP0935664B1公开(公告)日: 2009-06-24
- 发明人: LUBITZ, Werner , JECHLINGER, Wolfgang , SZOSTAK, Michael , WITTE,Angela
- 申请人: EVAX Technologies AG
- 申请人地址: Fraunhoferstrasse 10 82152 Martinsried/München DE
- 专利权人: EVAX Technologies AG
- 当前专利权人: EVAX Technologies AG
- 当前专利权人地址: Fraunhoferstrasse 10 82152 Martinsried/München DE
- 代理机构: Weiss, Wolfgang
- 优先权: DE19633698 19960821
- 国际公布: WO1998007874 19980226
- 主分类号: C12N15/73
- IPC分类号: C12N15/73 ; C12N15/10 ; A61K39/02
摘要:
The present invention concerns a process for selecting new PR- or PL-operator sequences of lambdoid phages which, compared to wild-type sequences, have a different thermostability for the binding of a repressor. In addition, the invention discloses new mutated PR- or PL- operator sequences and their use for temperature-regulated expression of genes and for producing improved vaccines.
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