发明公开
EP1132405A1 NOVEL G PROTEIN-COUPLED RECEPTOR PROTEIN, ITS DNA AND LIGAND THEREOF
审中-公开
灭菌剂G-PROTEIN GEKOPPELTES REZEPTORPROTEIN，DESSEN DNA UND LIGAND
- 专利标题： NOVEL G PROTEIN-COUPLED RECEPTOR PROTEIN, ITS DNA AND LIGAND THEREOF
- 专利标题（中）： 灭菌剂G-PROTEIN GEKOPPELTES REZEPTORPROTEIN，DESSEN DNA UND LIGAND
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申请号： EP99972224.2申请日： 1999-11-11
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公开(公告)号： EP1132405A1公开(公告)日： 2001-09-12
- 发明人: WATANABE, Takuya , KIKUCHI, Kuniko , TERAO, Yasuko , SHINTANI, Yasushi , HINUMA, Shuji , FUKUSUMI, Shoji , FUJII, Ryo , HOSOYA, Masaki , KITADA, Chieko
- 申请人： Takeda Chemical Industries, Ltd.
- 申请人地址： 1-1 Doshomachi 4-chome, Chuo-ku Osaka-shi, Osaka 541-0045 JP
- 专利权人： Takeda Chemical Industries, Ltd.
- 当前专利权人： Takeda Chemical Industries, Ltd.
- 当前专利权人地址： 1-1 Doshomachi 4-chome, Chuo-ku Osaka-shi, Osaka 541-0045 JP
- 代理机构： Keller, Günter, Dr.
- 优先权： JP32375998 19981113; JP6003099 19990308; JP10681299 19990414; JP16667299 19990614; JP22164099 19990804; JP25981899 19990914
- 国际公布： WO0029441 20000525
- 主分类号： C07K14/705
- IPC分类号： C07K14/705 ; C12N15/12 ; C12P21/02 ; C07K16/28 ; A61K39/395 ; G01N33/50 ; C07K2/00 ; A61K38/00
摘要：
The present invention relates to a novel polypeptide, its partial peptide or salt thereof, a method for manufacturing the polypeptide, a receptor of the polypeptide, a pharmaceutical composition comprising the polypeptide or the like, an antibody to the polypeptide, a method/kit for screening a compound that promotes or inhibits an activity of the polypeptide or salt thereof, a compound that can be obtained by the screening, a pharmaceutical composition comprising the compound, and the like.
The polypeptide, its partial peptide or the like of the present invention can be used, for example, as a therapeutic agent for nervous disease, a promoting agent for somatostatin secretion and the like. Further, the antibody of the present invention can be used for a quantification of the polypeptide of the present invention in a sample solution. Furthermore, the polypeptide of the present invention is useful for a reagent for screening a compound that promotes or inhibits the activity of the polypeptide of the present invention.
The polypeptide, its partial peptide or the like of the present invention can be used, for example, as a therapeutic agent for nervous disease, a promoting agent for somatostatin secretion and the like. Further, the antibody of the present invention can be used for a quantification of the polypeptide of the present invention in a sample solution. Furthermore, the polypeptide of the present invention is useful for a reagent for screening a compound that promotes or inhibits the activity of the polypeptide of the present invention.
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