发明公开
- 专利标题： DERIVES DE PYRROLE, LEUR PREPARATION ET LEUR UTILISATION EN THERAPEUTIQUE
- 专利标题（英）： Pyrrole derivatives, their preparation and their therapeutic use
- 专利标题（中）： 吡咯及其制备和治疗用途
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申请号： EP05796087.4申请日： 2005-08-02
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公开(公告)号： EP1781636A1公开(公告)日： 2007-05-09
- 发明人: BARTH, Francis , CONGY, Christian , HORTALA, Laurent , RINALDI-CARMONA, Murielle
- 申请人： Sanofi-Aventis
- 申请人地址： 174, Avenue de France 75013 Paris FR
- 专利权人： Sanofi-Aventis
- 当前专利权人： Sanofi-Aventis
- 当前专利权人地址： 174, Avenue de France 75013 Paris FR
- 代理机构： Kugel, Dominique
- 优先权： FR0408773 20040809
- 国际公布： WO2006024777 20060309
- 主分类号： C07D401/06
- IPC分类号： C07D401/06 ; C07D401/12 ; A61K31/435 ; C07D405/12 ; C07D403/12 ; C07D409/12
摘要：
The invention concerns compounds of formula (I), wherein: R1 represents hydrogen or a C1-C4 alkyl; R2 represents a C4-C10 group, a non-aromatic carbocyclic C3-C12 radical, an indianyl, a 1,2,3,4-tetrahydronaphthalenyl -1 or 2, a heterocyclic radical, a substituted C1-C3 alkylene group, a NR10R11 group; or R1 and R2 together with the nitrogen atom whereto they are bound form a heterocyclic radical. The invention also concerns the method for preparing said compounds and their therapeutic use.
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