发明公开
- 专利标题： HETEROCYCLIC RECEPTOR AGONISTS FOR THE TREATMENT OF DIABETES AND METABOLIC DISORDERS
- 专利标题（中）： 杂环受体激动剂糖尿病和代谢疾病的治疗
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申请号： EP07869989.9申请日： 2007-12-27
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公开(公告)号： EP2111107A2公开(公告)日： 2009-10-28
- 发明人: CHEN, Xin , CHENG, Peng , CLEMENS, L., Edward , JOHNSON, Jeffrey, D. , MA, Jingyuan , MURPHY, Alison , NASHASHIBI, Imad , RABBAT, Christopher, J. , SONG, Jiangao , WILSON, Maria, E. , ZHU, Yan , ZHAO, Zuchun
- 申请人： Metabolex Inc.
- 申请人地址： 3876 Bay Center Place Hayward, CA 94545 US
- 专利权人： Metabolex Inc.
- 当前专利权人： Metabolex Inc.
- 当前专利权人地址： 3876 Bay Center Place Hayward, CA 94545 US
- 代理机构： Marshall, Cameron John
- 优先权： US877903P 20061228; US964461 20071226
- 国际公布： WO2008083238 20080710
- 主分类号： A01N43/40
- IPC分类号： A01N43/40 ; A61K31/445 ; A61K31/497
摘要：
The present disclosure provides 2,4-disubstituted thiazoles of the general structure shown below that are agonists of G-protein coupled receptor (IC-GPCR2). Also, provided are compositions comprising these compounds as well as methods for using these compounds in a variety of applications including diabetes and metabolic disorders.
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