发明公开
EP2205592A1 POLYCYCLIC ARYL SUBSTITUTED TRIAZOLES AND POLYCYCLIC HETEROARYL SUBSTITUTED TRIAZOLES USEFUL AS AXL INHIBITORS
有权
BY取代的三唑和多环杂芳基取代三唑本身AS AXL抑制剂SUITABLE环芳基
- 专利标题： POLYCYCLIC ARYL SUBSTITUTED TRIAZOLES AND POLYCYCLIC HETEROARYL SUBSTITUTED TRIAZOLES USEFUL AS AXL INHIBITORS
- 专利标题（中）： BY取代的三唑和多环杂芳基取代三唑本身AS AXL抑制剂SUITABLE环芳基
-
申请号： EP07870108.3申请日： 2007-12-29
-
公开(公告)号： EP2205592A1公开(公告)日： 2010-07-14
- 发明人: GOFF, Dane , ZHANG, Jing , SINGH, Rajinder , HOLLAND, Sacha , YU, Jiaxin , HECKRODT, Thilo , DING, Pingyu , LITVAK, Joane
- 申请人： Rigel Pharmaceuticals, Inc.
- 申请人地址： 1180 Veterans Boulevard South San Francisco, CA 94080 US
- 专利权人： Rigel Pharmaceuticals, Inc.
- 当前专利权人： Rigel Pharmaceuticals, Inc.
- 当前专利权人地址： 1180 Veterans Boulevard South San Francisco, CA 94080 US
- 代理机构： Grünecker, Kinkeldey, Stockmair & Schwanhäusser Anwaltssozietät
- 优先权： US983107P 20071026
- 国际公布： WO2009054864 20090430
- 主分类号： C07D403/04
- IPC分类号： C07D403/04 ; C07D403/14 ; C07D471/18 ; C07D491/14 ; A61K31/4196 ; A61P19/00 ; A61P35/00
摘要：
Polycyclic aryl and polycyclic heteroaryl substituted triazoles and pharmaceutical compositions containing the compounds are disclosed as being useful in inhibiting the activity of the receptor protein tyrosine kinase Axl. Methods of using the compounds in treating diseases or conditions associated with Axl catalytic activity are also disclosed.
公开/授权文献
信息查询
